Effect of progressive resistance exercise on strength evolution of elderly patients living with HIV compared to healthy controls

Human Immunodeficiency Virus (HIV) infection worsens the frailty of elderly people, compromising their quality of life. In this study we prospectively evaluated eleven patients living with HIV and 21 controls older than 60 years and without prior regular physical activity, who engaged in a one-year...

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Published inClinics (São Paulo, Brazil) Vol. 66; no. 2; pp. 261 - 266
Main Authors de Souza, Paula Maria Loiola, Jacob-Filho, Wilson, Santarém, José Maria, Zomignan, Adriana Almeida, Burattini, Marcelo Nascimento
Format Journal Article
LanguageEnglish
Portuguese
Published Brazil Elsevier España, S.L.U 01.01.2011
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
Faculdade de Medicina / USP
Elsevier España
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Abstract Human Immunodeficiency Virus (HIV) infection worsens the frailty of elderly people, compromising their quality of life. In this study we prospectively evaluated eleven patients living with HIV and 21 controls older than 60 years and without prior regular physical activity, who engaged in a one-year progressive resistance exercise program to compare its effects on muscular strength, physical fitness and body composition. Exercises for major muscular groups were performed 2 times/week, under professional supervision. Strength increase was evaluated bimonthly, while body composition, lipid and glycaemic profiles (only of those living with HIV) and physical fitness were evaluated before and after the one-year training. The participants living with HIV were lighter, had smaller Body Mass Index and were initially much weaker than controls. However, their strength increased more (1.52-2.33 times the baseline values for those living with HIV x 1.21-1.48 times for controls, p<0.01), nullifying the differences initially seen. These effects were seen independently of gender, age or baseline physical activity. In addition, those living with HIV improved their fasting glucose levels and showed a tendency to improve their lipids after the one year training program. These effects were slightly more pronounced among those not using protease inhibitors, although not significantly. Resistance exercise safely increased the strength of older patients living with HIV adults, allowing them to achieve performance levels observed among otherwise healthy controls. These findings favor the recommendation of resistance exercise for elderly adults living with HIV adults.
AbstractList OBJECTIVES: Human Immunodeficiency Virus (HIV) infection worsens the frailty of elderly people, compromising their quality of life. In this study we prospectively evaluated eleven patients living with HIV and 21 controls older than 60 years and without prior regular physical activity, who engaged in a one-year progressive resistance exercise program to compare its effects on muscular strength, physical fitness and body composition. METHODS: Exercises for major muscular groups were performed 2 times/week, under professional supervision. Strength increase was evaluated bimonthly, while body composition, lipid and glycaemic profiles (only of those living with HIV) and physical fitness were evaluated before and after the one-year training. RESULTS: The participants living with HIV were lighter, had smaller Body Mass Index and were initially much weaker than controls. However, their strength increased more (1.52-2.33 times the baseline values for those living with HIV x 1.21-1.48 times for controls, p<0.01), nullifying the differences initially seen. These effects were seen independently of gender, age or baseline physical activity. In addition, those living with HIV improved their fasting glucose levels and showed a tendency to improve their lipids after the one year training program. These effects were slightly more pronounced among those not using protease inhibitors, although not significantly. CONCLUSIONS: Resistance exercise safely increased the strength of older patients living with HIV adults, allowing them to achieve performance levels observed among otherwise healthy controls. These findings favor the recommendation of resistance exercise for elderly adults living with HIV adults.
OBJECTIVESHuman Immunodeficiency Virus (HIV) infection worsens the frailty of elderly people, compromising their quality of life. In this study we prospectively evaluated eleven patients living with HIV and 21 controls older than 60 years and without prior regular physical activity, who engaged in a one-year progressive resistance exercise program to compare its effects on muscular strength, physical fitness and body composition. METHODSExercises for major muscular groups were performed 2 times/week, under professional supervision. Strength increase was evaluated bimonthly, while body composition, lipid and glycaemic profiles (only of those living with HIV) and physical fitness were evaluated before and after the one-year training. RESULTSThe participants living with HIV were lighter, had smaller Body Mass Index and were initially much weaker than controls. However, their strength increased more (1.52-2.33 times the baseline values for those living with HIV x 1.21-1.48 times for controls, p<0.01), nullifying the differences initially seen. These effects were seen independently of gender, age or baseline physical activity. In addition, those living with HIV improved their fasting glucose levels and showed a tendency to improve their lipids after the one year training program. These effects were slightly more pronounced among those not using protease inhibitors, although not significantly. CONCLUSIONSResistance exercise safely increased the strength of older patients living with HIV adults, allowing them to achieve performance levels observed among otherwise healthy controls. These findings favor the recommendation of resistance exercise for elderly adults living with HIV adults.
Human Immunodeficiency Virus (HIV) infection worsens the frailty of elderly people, compromising their quality of life. In this study we prospectively evaluated eleven patients living with HIV and 21 controls older than 60 years and without prior regular physical activity, who engaged in a one-year progressive resistance exercise program to compare its effects on muscular strength, physical fitness and body composition. Exercises for major muscular groups were performed 2 times/week, under professional supervision. Strength increase was evaluated bimonthly, while body composition, lipid and glycaemic profiles (only of those living with HIV) and physical fitness were evaluated before and after the one-year training. The participants living with HIV were lighter, had smaller Body Mass Index and were initially much weaker than controls. However, their strength increased more (1.52-2.33 times the baseline values for those living with HIV x 1.21-1.48 times for controls, p<0.01), nullifying the differences initially seen. These effects were seen independently of gender, age or baseline physical activity. In addition, those living with HIV improved their fasting glucose levels and showed a tendency to improve their lipids after the one year training program. These effects were slightly more pronounced among those not using protease inhibitors, although not significantly. Resistance exercise safely increased the strength of older patients living with HIV adults, allowing them to achieve performance levels observed among otherwise healthy controls. These findings favor the recommendation of resistance exercise for elderly adults living with HIV adults.
Author Santarém, José Maria
Burattini, Marcelo Nascimento
de Souza, Paula Maria Loiola
Jacob-Filho, Wilson
Zomignan, Adriana Almeida
AuthorAffiliation Universidade de São Paulo
Universidade Federal de São Paulo
AuthorAffiliation_xml – name: Universidade de São Paulo
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  givenname: Paula Maria Loiola
  surname: de Souza
  fullname: de Souza, Paula Maria Loiola
  organization: Discipline of Medical Informatics & LIM 01 – Department of Pathology, Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, Brazil
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  givenname: Wilson
  surname: Jacob-Filho
  fullname: Jacob-Filho, Wilson
  organization: Medical Clinics Department, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil
– sequence: 3
  givenname: José Maria
  surname: Santarém
  fullname: Santarém, José Maria
  organization: Medical Clinics Department, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil
– sequence: 4
  givenname: Adriana Almeida
  surname: Zomignan
  fullname: Zomignan, Adriana Almeida
  organization: Centro de Estudos em Ciências da Atividade Física – CECAFI, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil
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  givenname: Marcelo Nascimento
  surname: Burattini
  fullname: Burattini, Marcelo Nascimento
  email: mnburatt@usp.br
  organization: Discipline of Medical Informatics & LIM 01 – Department of Pathology, Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, Brazil
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Issue 2
Keywords Exercise
Muscular strength
HIV
Elderly adults
Resistance exercise
Language English
Portuguese
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Snippet Human Immunodeficiency Virus (HIV) infection worsens the frailty of elderly people, compromising their quality of life. In this study we prospectively...
OBJECTIVESHuman Immunodeficiency Virus (HIV) infection worsens the frailty of elderly people, compromising their quality of life. In this study we...
OBJECTIVES: Human Immunodeficiency Virus (HIV) infection worsens the frailty of elderly people, compromising their quality of life. In this study we...
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StartPage 261
SubjectTerms Aged
Body Composition - physiology
Case-Control Studies
Clinical Science
Elderly adults
Exercise
Female
Frail Elderly
HIV
HIV Infections - physiopathology
Humans
Male
MEDICINE, GENERAL & INTERNAL
Muscle Strength - physiology
Muscular strength
Physical Fitness - physiology
Prospective Studies
Resistance exercise
Resistance Training
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Title Effect of progressive resistance exercise on strength evolution of elderly patients living with HIV compared to healthy controls
URI https://dx.doi.org/10.1590/S1807-59322011000200014
https://www.ncbi.nlm.nih.gov/pubmed/21484044
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https://pubmed.ncbi.nlm.nih.gov/PMC3059853
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https://doaj.org/article/f2d1487a8ed14053afda3aa6f6e89553
Volume 66
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