Measuring Drug Occupancy in the Absence of a Reference Region: The Lassen Plot Re-Visited - Cunningham, Vincent J; Rabiner, Eugenii A; Slifstein, Mark; Laruelle, Marc; Gunn, Roger N (Journal of cerebral blood flow and metabolism, 2010)
Keywords: Algorithms; Biological and medical sciences; Brain - diagnostic imaging; Brief Communication; Drug toxicity and drugs side effects treatment; Humans; Image Processing, Computer-Assisted; Medical sciences; Miscellaneous (drug allergy, mutagens, teratogens...); Monte Carlo Method; Neurology; Pharmaceutical Preparations - metabolism; Pharmacology. Drug treatments; Piperazines - metabolism; Positron-Emission Tomography; Pyridines - metabolism; Receptor, Serotonin, 5-HT1A - drug effects; Receptors, Drug - metabolism; Serotonin Antagonists - metabolism; Vascular diseases and vascular malformations of the nervous system; occupancy; PET; graphical analysis; Nervous system diseases; Central nervous system disease; Positron emission tomography; Cerebrovascular disease; Cerebral disorder; Emission tomography