Report of the Tunisian Registry of Primary Immunodeficiencies: 25-Years of Experience (1988–2012)

• Published in: Journal of clinical immunology Vol. 35; no. 8; pp. 745 - 753
• Main Authors: Mellouli, Fethi, Mustapha, Imen Ben, Khaled, Monia Ben, Besbes, Habib, Ouederni, Monia, Mekki, Najla, Ali, Meriem Ben, Larguèche, Beya, Hachicha, Mongia, Sfar, Tahar, Gueddiche, Neji, Barsaoui, Siheme, Sammoud, Azza, Boussetta, Khadija, Becher, Saida Ben, Meherzi, Ahmed, Guandoura, Najoua, Boughammoura, Lamia, Harbi, Abdelaziz, Amri, Fethi, Bayoudh, Fethi, Jaballah, Najla Ben, Tebib, Neji, Bouaziz, Asma, Mahfoudh, Abdelmajid, Aloulou, Hajer, Mansour, Lamia Ben, Chabchoub, Imen, Boussoffara, Raoudha, Chemli, Jalel, Bouguila, Jihène, Hassayoun, Saida, Hammami, Saber, Habboul, Zakia, Hamzaoui, Agnès, Ammar, Jamel, Barbouche, Mohamed-Ridha, Bejaoui, Mohamed
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.11.2015; Springer Nature B.V; Springer Verlag
• Subjects: Age of Onset; Antibodies - genetics; Antibodies - metabolism; B-Lymphocytes - physiology; Biomedical and Life Sciences; Biomedicine; Complement System Proteins - genetics; Consanguinity; Female; Humans; Immunologic Deficiency Syndromes - classification; Immunologic Deficiency Syndromes - epidemiology; Immunologic Deficiency Syndromes - mortality; Immunology; Infant; Infectious Diseases; Internal Medicine; Life Sciences; Male; Medical Microbiology; Original Article; Prevalence; Registries; Survival Analysis; T-Lymphocytes - physiology; Tunisia; Tunisia; diagnosis; Primary immunodeficiencies; management; Tunisia; treatments

Purpose Primary immunodeficiencies (PIDs) are a large group of diseases characterized by susceptibility to not only recurrent infections but also autoimmune diseases and malignancies. The aim of this study was to describe and analyze the distribution, clinical features and eventual outcome of PID am...