Assessment of Regional Differences in Tariquidar-Induced P-Glycoprotein Modulation at the Human Blood–Brain Barrier - Bauer, Martin; Karch, Rudolf; Neumann, Friederike; Wagner, Claudia C; Kletter, Kurt; Müller, Markus; Löscher, Wolfgang; Zeitlinger, Markus; Langer, Oliver (Journal of cerebral blood flow and metabolism, 2010)
Keywords: Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1 - physiology; Biological and medical sciences; Blood-Brain Barrier - drug effects; Blood-Brain Barrier - physiology; Brain - diagnostic imaging; Brief Communication; Calcium Channel Blockers - metabolism; Drug Resistance, Multiple - drug effects; Epilepsy - chemically induced; Epilepsy - physiopathology; Humans; Image Processing, Computer-Assisted; Infusions, Intravenous; Investigative techniques, diagnostic techniques (general aspects); Male; Medical sciences; Nervous system; Neurology; Positron-Emission Tomography; Quinolines - pharmacology; Ultrasonic investigative techniques; Vascular diseases and vascular malformations of the nervous system; Verapamil - metabolism; P-glycoprotein; blood–brain barrier; tariquidar; positron emission tomography (PET); regional; (R)-[11C]verapamil; Antineoplastic agent; Human; blood-brain barrier; Nervous system diseases; regional tariquidar; Tariquidar; Calcium antagonist; Glycoprotein; C]verapamil; Antiarrhythmic agent; Blood brain barrier; Cerebral disorder; Central nervous system disease; Aralkylamine; Verapamil; Positron emission tomography; (R)-; Cerebrovascular disease; Emission tomography