High-Intensity Interval Training in Older Adults: a Scoping Review

High-intensity interval training (HIIT) is an increasingly popular form of aerobic exercise which includes bouts of high-intensity exercise interspersed with periods of rest. The health benefits, risks, and optimal design of HIIT are still unclear. Further, most research on HIIT has been done in you...

Full description

Saved in:
Bibliographic Details
Published inSports medicine - open Vol. 7; no. 1; p. 49
Main Authors Marriott, Catherine F. S., Petrella, Andrea F. M., Marriott, Emily C. S., Boa Sorte Silva, Narlon C., Petrella, Robert J.
Format Journal Article
LanguageEnglish
Published Cham Springer International Publishing 01.12.2021
Springer Nature B.V
Subjects
Online AccessGet full text

Cover

Loading…
Abstract High-intensity interval training (HIIT) is an increasingly popular form of aerobic exercise which includes bouts of high-intensity exercise interspersed with periods of rest. The health benefits, risks, and optimal design of HIIT are still unclear. Further, most research on HIIT has been done in young and middle-aged adults, and as such, the tolerability and effects in senior populations are less well-known. The purpose of this scoping review was to characterize HIIT research that has been done in older adults including protocols, feasibility, and safety and to identify gaps in the current knowledge. Five databases were searched with variations of the terms, “high-intensity interval training” and “older adults” for experimental or quasi-experimental studies published in or after 2009. Studies were included if they had a treatment group with a mean age of 65 years or older who did HIIT, exclusively. Of 4644 papers identified, 69 met the inclusion criteria. The average duration of training was 7.9 (7.0) weeks (mean [SD]) and protocols ranged widely. The average sample size was 47.0 (65.2) subjects (mean [SD]). Healthy populations were the most studied group ( n = 30), followed by subjects with cardiovascular ( n = 12) or cardiac disease ( n = 9), metabolic dysfunction ( n = 8), and others ( n = 10). The most common primary outcomes included changes in cardiorespiratory fitness (such as VO 2peak ) as well as feasibility and safety of the protocols as measured by the number of participant dropouts, adverse events, and compliance rate. HIIT protocols were diverse but were generally well-tolerated and may confer many health advantages to older adults. Larger studies and more research in clinical populations most representative of older adults are needed to further evaluate the clinical effects of HIIT in these groups.
AbstractList High-intensity interval training (HIIT) is an increasingly popular form of aerobic exercise which includes bouts of high-intensity exercise interspersed with periods of rest. The health benefits, risks, and optimal design of HIIT are still unclear. Further, most research on HIIT has been done in young and middle-aged adults, and as such, the tolerability and effects in senior populations are less well-known. The purpose of this scoping review was to characterize HIIT research that has been done in older adults including protocols, feasibility, and safety and to identify gaps in the current knowledge. Five databases were searched with variations of the terms, “high-intensity interval training” and “older adults” for experimental or quasi-experimental studies published in or after 2009. Studies were included if they had a treatment group with a mean age of 65 years or older who did HIIT, exclusively. Of 4644 papers identified, 69 met the inclusion criteria. The average duration of training was 7.9 (7.0) weeks (mean [SD]) and protocols ranged widely. The average sample size was 47.0 (65.2) subjects (mean [SD]). Healthy populations were the most studied group ( n = 30), followed by subjects with cardiovascular ( n = 12) or cardiac disease ( n = 9), metabolic dysfunction ( n = 8), and others ( n = 10). The most common primary outcomes included changes in cardiorespiratory fitness (such as VO 2peak ) as well as feasibility and safety of the protocols as measured by the number of participant dropouts, adverse events, and compliance rate. HIIT protocols were diverse but were generally well-tolerated and may confer many health advantages to older adults. Larger studies and more research in clinical populations most representative of older adults are needed to further evaluate the clinical effects of HIIT in these groups.
High-intensity interval training (HIIT) is an increasingly popular form of aerobic exercise which includes bouts of high-intensity exercise interspersed with periods of rest. The health benefits, risks, and optimal design of HIIT are still unclear. Further, most research on HIIT has been done in young and middle-aged adults, and as such, the tolerability and effects in senior populations are less well-known. The purpose of this scoping review was to characterize HIIT research that has been done in older adults including protocols, feasibility, and safety and to identify gaps in the current knowledge. Five databases were searched with variations of the terms, "high-intensity interval training" and "older adults" for experimental or quasi-experimental studies published in or after 2009. Studies were included if they had a treatment group with a mean age of 65 years or older who did HIIT, exclusively. Of 4644 papers identified, 69 met the inclusion criteria. The average duration of training was 7.9 (7.0) weeks (mean [SD]) and protocols ranged widely. The average sample size was 47.0 (65.2) subjects (mean [SD]). Healthy populations were the most studied group (n = 30), followed by subjects with cardiovascular (n = 12) or cardiac disease (n = 9), metabolic dysfunction (n = 8), and others (n = 10). The most common primary outcomes included changes in cardiorespiratory fitness (such as VO ) as well as feasibility and safety of the protocols as measured by the number of participant dropouts, adverse events, and compliance rate. HIIT protocols were diverse but were generally well-tolerated and may confer many health advantages to older adults. Larger studies and more research in clinical populations most representative of older adults are needed to further evaluate the clinical effects of HIIT in these groups.
High-intensity interval training (HIIT) is an increasingly popular form of aerobic exercise which includes bouts of high-intensity exercise interspersed with periods of rest. The health benefits, risks, and optimal design of HIIT are still unclear. Further, most research on HIIT has been done in young and middle-aged adults, and as such, the tolerability and effects in senior populations are less well-known. The purpose of this scoping review was to characterize HIIT research that has been done in older adults including protocols, feasibility, and safety and to identify gaps in the current knowledge. Five databases were searched with variations of the terms, “high-intensity interval training” and “older adults” for experimental or quasi-experimental studies published in or after 2009. Studies were included if they had a treatment group with a mean age of 65 years or older who did HIIT, exclusively. Of 4644 papers identified, 69 met the inclusion criteria. The average duration of training was 7.9 (7.0) weeks (mean [SD]) and protocols ranged widely. The average sample size was 47.0 (65.2) subjects (mean [SD]). Healthy populations were the most studied group (n = 30), followed by subjects with cardiovascular (n = 12) or cardiac disease (n = 9), metabolic dysfunction (n = 8), and others (n = 10). The most common primary outcomes included changes in cardiorespiratory fitness (such as VO2peak) as well as feasibility and safety of the protocols as measured by the number of participant dropouts, adverse events, and compliance rate. HIIT protocols were diverse but were generally well-tolerated and may confer many health advantages to older adults. Larger studies and more research in clinical populations most representative of older adults are needed to further evaluate the clinical effects of HIIT in these groups.
ArticleNumber 49
Author Petrella, Andrea F. M.
Petrella, Robert J.
Boa Sorte Silva, Narlon C.
Marriott, Emily C. S.
Marriott, Catherine F. S.
Author_xml – sequence: 1
  givenname: Catherine F. S.
  surname: Marriott
  fullname: Marriott, Catherine F. S.
  organization: Centre for Studies in Family Medicine, Department of Family Medicine, Schulich School of Medicine and Dentistry, Western University
– sequence: 2
  givenname: Andrea F. M.
  surname: Petrella
  fullname: Petrella, Andrea F. M.
  organization: Centre for Studies in Family Medicine, Department of Family Medicine, Schulich School of Medicine and Dentistry, Western University
– sequence: 3
  givenname: Emily C. S.
  surname: Marriott
  fullname: Marriott, Emily C. S.
  organization: Centre for Studies in Family Medicine, Department of Family Medicine, Schulich School of Medicine and Dentistry, Western University
– sequence: 4
  givenname: Narlon C.
  surname: Boa Sorte Silva
  fullname: Boa Sorte Silva, Narlon C.
  organization: Centre for Studies in Family Medicine, Department of Family Medicine, Schulich School of Medicine and Dentistry, Western University, Aging, Mobility, and Cognitive Neuroscience Lab, Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Department of Physical Therapy, Faculty of Medicine, University of British Columbia
– sequence: 5
  givenname: Robert J.
  surname: Petrella
  fullname: Petrella, Robert J.
  email: petrella@uwo.ca
  organization: Centre for Studies in Family Medicine, Department of Family Medicine, Schulich School of Medicine and Dentistry, Western University, School of Kinesiology, Western University, School of Kinesiology, Faculty of Education, University of British Columbia, Department of Family Practice, Faculty of Medicine, University of British Columbia
BackLink https://www.ncbi.nlm.nih.gov/pubmed/34279765$$D View this record in MEDLINE/PubMed
BookMark eNp9UctKAzEUDVLRWv0BFzLgejTPmcSFUIvagiD4WIfMJFMjY6Ym00r_3kxbn4uucsl53MM9B6DnGmcAOEbwDCGenQcKc8FTiFEKIaE0pTugj1H8EnmGeqtZpAjlcB8chWALyCCllECyB_YJxXmksT64GtvpSzpxrXHBtsukm_xC1cmTV9ZZN02sS-5rbXwy1PO6DReJSh7LZtZBD2Zhzcch2K1UHczR5h2A55vrp9E4vbu_nYyGd2nJctGmCOtCC4gYVFRkOayoMDRXGeecMlpURHNIKop0HkEFK4ZNpgiqtDFZBYUmA3C59p3NizejS-Nar2o58_ZN-aVslJV_EWdf5LRZSI65EAxFg9ONgW_e5ya08rWZexczS8wYQZgJwiPr5Peab_-vm0UCXhNK34TgTfVNQVB23ch1NzJ2I1fdSBpF_J-otK1qbdNFtfV2KVlLQ9zjpsb_xN6i-gSD6qI1
CitedBy_id crossref_primary_10_1038_s41598_025_91833_z
crossref_primary_10_1080_01924788_2022_2148416
crossref_primary_10_1371_journal_pone_0293357
crossref_primary_10_23736_S0022_4707_23_14596_8
crossref_primary_10_1681_ASN_0000000636
crossref_primary_10_1152_japplphysiol_00491_2023
crossref_primary_10_7600_jpfsm_11_263
crossref_primary_10_1186_s40798_024_00767_9
crossref_primary_10_1093_ehjci_jeac106
crossref_primary_10_1007_s11332_024_01308_3
crossref_primary_10_1093_eurheartj_ehac244
crossref_primary_10_1159_000536363
crossref_primary_10_1007_s00395_024_01034_4
crossref_primary_10_1186_s11556_024_00337_8
crossref_primary_10_1186_s12889_024_20357_4
crossref_primary_10_3390_jcm13051299
crossref_primary_10_1186_s12877_022_03208_y
crossref_primary_10_1038_s41514_022_00089_8
crossref_primary_10_31146_1682_8658_ecg_228_8_226_241
crossref_primary_10_3390_ijerph182211809
crossref_primary_10_1016_j_jnha_2024_100401
crossref_primary_10_5812_mejrh_121818
crossref_primary_10_12998_wjcc_v10_i23_8323
crossref_primary_10_1042_CS20231197
crossref_primary_10_14814_phy2_70136
crossref_primary_10_3389_fphys_2023_1223069
crossref_primary_10_1038_s41598_025_90719_4
crossref_primary_10_1177_00912174241291716
crossref_primary_10_24859_SaberDigital_2024v17n3_1585
crossref_primary_10_3390_life14101343
crossref_primary_10_3389_fragi_2024_1356954
crossref_primary_10_3389_fnins_2023_1229307
crossref_primary_10_1016_j_arr_2022_101698
crossref_primary_10_1186_s40798_023_00613_4
crossref_primary_10_2196_41421
crossref_primary_10_3389_fcvm_2024_1376861
crossref_primary_10_3390_life13051224
crossref_primary_10_1111_jch_14610
crossref_primary_10_12779_dnd_2022_21_3_93
crossref_primary_10_1016_j_psychsport_2024_102647
Cites_doi 10.1080/1364557032000119616
10.3390/ijerph17031083
10.1016/j.jsams.2018.11.026
10.1177/1741826711430926
10.1123/japa.2020-0093
10.1123/japa.2018-0309
10.1249/MSS.0b013e3182199834
10.3389/fimmu.2020.00729
10.1161/STROKEAHA.119.027450
10.3389/fphys.2019.00264
10.7717/peerj.4738
10.3389/fpubh.2017.00335
10.1007/s40279-015-0365-0
10.1093/ptj/86.4.489
10.1249/MSS.0000000000001229
10.1186/s12967-020-02261-8
10.1249/MSS.0000000000002226
10.1007/s00421-009-1011-z
10.1007/s11357-016-9882-5
10.1007/s11739-013-0980-4
10.1002/bjs.10669
10.1186/s12877-015-0017-0
10.1007/s00421-019-04162-1
10.1002/agm2.12127
10.1249/MSS.0000000000001070
10.1007/s40279-014-0259-6
10.1123/jpah.2018-0189
10.1152/ajpheart.00379.2017
10.1016/j.ijcard.2011.11.086
10.1007/s40279-013-0029-x
10.1152/japplphysiol.00935.2016
10.1249/MSS.0b013e31828bbbd4
10.3389/fphys.2019.00019
10.1161/CIRCULATIONAHA.116.022924
10.3389/fendo.2017.00132
10.1007/s11332-018-0498-2
10.4061/2011/984683
10.1016/j.jsams.2009.09.008
10.1519/JSC.0000000000003933
10.1016/S0140-6736(14)61347-7
10.1016/j.jash.2016.02.011
10.2340/16501977-2043
10.3389/fphys.2018.00203
10.18632/oncotarget.4031
10.1007/s11357-016-9897-y
10.1016/j.cjca.2017.09.019
10.1089/rej.2018.2069
10.3233/JAD-150817
10.1055/s-0029-1246140
10.1007/s00421-009-1287-z
10.1016/j.exger.2018.12.013
10.1016/j.exger.2017.02.069
10.1186/s13195-021-00774-y
10.1152/japplphysiol.00518.2014
10.1111/obr.12532
10.1177/2047487313519345
10.1080/17437199.2017.1326011
10.1186/s13075-018-1605-0
10.31729/jnma.318
10.14814/phy2.13219
10.1113/jphysiol.2012.235127
10.24095/hpcdp.35.6.01
10.1016/j.diabet.2016.07.031
10.1177/1479972315598691
10.1113/JP277648
10.1152/japplphysiol.00852.2004
10.1136/bjsports-2013-092576
10.1249/MSS.0000000000001501
10.1186/s13075-018-1786-6
10.1139/apnm-2019-0495
10.1111/apha.12601
10.1177/1545968317718269
10.1152/ajpheart.00344.2017
10.1016/j.ijcard.2011.10.075
10.1111/obr.12536
10.1016/j.pcad.2017.03.006
10.1016/j.apunts.2017.11.003
10.1007/s12603-011-0087-4
10.1111/acel.12861
10.1016/j.ijcard.2019.07.023
10.3390/brainsci10110796
10.3390/sports7040094
10.1212/WNL.0000000000000644
10.1249/MSS.0b013e318260ff92
10.1016/j.exger.2016.06.009
10.1111/crj.12189
10.1155/2018/8913187
10.1186/s11556-017-0184-4
ContentType Journal Article
Copyright The Author(s) 2021
2021. The Author(s).
The Author(s) 2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
Copyright_xml – notice: The Author(s) 2021
– notice: 2021. The Author(s).
– notice: The Author(s) 2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
DBID C6C
AAYXX
CITATION
NPM
3V.
7RV
7TS
7XB
8FI
8FJ
8FK
ABUWG
AFKRA
AZQEC
BENPR
CCPQU
DWQXO
FYUFA
GHDGH
KB0
NAPCQ
PHGZM
PHGZT
PIMPY
PKEHL
PPXIY
PQEST
PQQKQ
PQUKI
PRINS
5PM
DOI 10.1186/s40798-021-00344-4
DatabaseName Springer Nature OA Free Journals
CrossRef
PubMed
ProQuest Central (Corporate)
Nursing & Allied Health Database
Physical Education Index
ProQuest Central (purchase pre-March 2016)
Hospital Premium Collection
Hospital Premium Collection (Alumni Edition)
ProQuest Central (Alumni) (purchase pre-March 2016)
ProQuest Central (Alumni)
ProQuest Central UK/Ireland
ProQuest Central Essentials
ProQuest Central
ProQuest One Community College
ProQuest Central Korea
Health Research Premium Collection
Health Research Premium Collection (Alumni)
Nursing & Allied Health Database (Alumni Edition)
Nursing & Allied Health Premium
ProQuest Central Premium
ProQuest One Academic
ProQuest Publicly Available Content
ProQuest One Academic Middle East (New)
ProQuest One Health & Nursing
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Academic
ProQuest One Academic UKI Edition
ProQuest Central China
PubMed Central (Full Participant titles)
DatabaseTitle CrossRef
PubMed
Publicly Available Content Database
ProQuest One Academic Middle East (New)
ProQuest Central Essentials
ProQuest One Academic Eastern Edition
ProQuest Central (Alumni Edition)
ProQuest One Community College
ProQuest One Health & Nursing
ProQuest Nursing & Allied Health Source
ProQuest Hospital Collection
Health Research Premium Collection (Alumni)
ProQuest Central China
ProQuest Hospital Collection (Alumni)
Physical Education Index
ProQuest Central
Nursing & Allied Health Premium
Health Research Premium Collection
ProQuest One Academic UKI Edition
ProQuest Central Korea
ProQuest Nursing & Allied Health Source (Alumni)
ProQuest Central (New)
ProQuest One Academic
ProQuest One Academic (New)
ProQuest Central (Alumni)
DatabaseTitleList

PubMed
CrossRef
Publicly Available Content Database
Database_xml – sequence: 1
  dbid: C6C
  name: (Open Access) Springer Nature eJournals
  url: http://www.springeropen.com/
  sourceTypes: Publisher
– sequence: 2
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 3
  dbid: BENPR
  name: ProQuest Central
  url: https://www.proquest.com/central
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
EISSN 2198-9761
ExternalDocumentID PMC8289951
34279765
10_1186_s40798_021_00344_4
Genre Journal Article
Scoping Review
GrantInformation_xml – fundername: schulich school of medicine and dentistry
  grantid: SROP
  funderid: http://dx.doi.org/10.13039/501100008093
– fundername: schulich school of medicine and dentistry
  grantid: SROP
– fundername: ;
  grantid: SROP
GroupedDBID 0R~
4.4
53G
5VS
7RV
8FI
8FJ
AAFWJ
AAJSJ
AAKKN
ABEEZ
ABUWG
ACACY
ACGFS
ACULB
ADBBV
ADINQ
ADRAZ
AFGXO
AFKRA
AFPKN
AHBYD
AHSBF
AHYZX
ALIPV
ALMA_UNASSIGNED_HOLDINGS
AMKLP
AOIJS
ASPBG
AVWKF
BAPOH
BCNDV
BENPR
BFQNJ
BKEYQ
BPHCQ
BVXVI
C24
C6C
CCPQU
EBLON
EBS
EIHBH
EJD
FYUFA
GROUPED_DOAJ
HYE
IAO
IHR
ITC
KQ8
M48
M~E
NAPCQ
OK1
PGMZT
PIMPY
PQQKQ
PROAC
RPM
RSV
SOJ
UKHRP
AASML
AAYXX
CITATION
IPT
PHGZM
PHGZT
NPM
3V.
7TS
7XB
8FK
AZQEC
DWQXO
PKEHL
PPXIY
PQEST
PQUKI
PRINS
5PM
ID FETCH-LOGICAL-c579t-12dbd90150a49670f49e47a6888454bf3d803f41d7670a0f52e6a31fdee6f09d3
IEDL.DBID M48
ISSN 2199-1170
IngestDate Thu Aug 21 14:08:53 EDT 2025
Sun Jul 13 03:09:14 EDT 2025
Mon Jul 21 05:27:32 EDT 2025
Thu Apr 24 23:12:30 EDT 2025
Tue Jul 01 03:39:46 EDT 2025
Fri Feb 21 02:48:04 EST 2025
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 1
Keywords High-intensity interval training
Chronic disease
Older adults
Seniors
Language English
License 2021. The Author(s).
Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c579t-12dbd90150a49670f49e47a6888454bf3d803f41d7670a0f52e6a31fdee6f09d3
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
content type line 14
ObjectType-Literature Review-2
ObjectType-Feature-3
OpenAccessLink http://journals.scholarsportal.info/openUrl.xqy?doi=10.1186/s40798-021-00344-4
PMID 34279765
PQID 2553125938
PQPubID 4402907
ParticipantIDs pubmedcentral_primary_oai_pubmedcentral_nih_gov_8289951
proquest_journals_2553125938
pubmed_primary_34279765
crossref_primary_10_1186_s40798_021_00344_4
crossref_citationtrail_10_1186_s40798_021_00344_4
springer_journals_10_1186_s40798_021_00344_4
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate 2021-12-01
PublicationDateYYYYMMDD 2021-12-01
PublicationDate_xml – month: 12
  year: 2021
  text: 2021-12-01
  day: 01
PublicationDecade 2020
PublicationPlace Cham
PublicationPlace_xml – name: Cham
– name: Switzerland
– name: Heidelberg
PublicationTitle Sports medicine - open
PublicationTitleAbbrev Sports Med - Open
PublicationTitleAlternate Sports Med Open
PublicationYear 2021
Publisher Springer International Publishing
Springer Nature B.V
Publisher_xml – name: Springer International Publishing
– name: Springer Nature B.V
References Munch GW, Iepsen UW, Ryrsø CK, Rosenmeier JB, Pedersen BK, Mortensen SP. Effect of 6 weeks of high-intensity one-legged cycling on functional sympatholysis and ATP signaling in patients with heart failure. Am J Physiol Circ Physiol; 2017;314:ajpheart.00379.
BruseghiniPTamECalabriaEMilaneseCCapelliCGalvaniCHigh intensity interval training does not have compensatory effects on physical activity levels in older adultsInt J Environ Res Public Health.2020173108310.3390/ijerph170310837037169
UcEYDoerschugKCMagnottaVDawsonJDThomsenTRKlineJNRizzoMNewmanSRMehtaSGrabowskiTJBrussJBlanchetteDRAndersonSWVossMWKramerAFDarlingWGPhase I/II randomized trial of aerobic exercise in Parkinson disease in a community settingNeurology.201483541342510.1212/WNL.0000000000000644249910374132568
ThijssenDHJBendaNMMKerstensTPSeegerJPHvan DijkAPJHopmanMTE12-week exercise training, independent of the type of exercise, attenuates endothelial ischaemia-reperfusion injury in heart failure patientsFront Physiol20191026430930798642876310.3389/fphys.2019.00264
O’BrienMWJohnsJARobinsonSABungayAMekarySKimmerlyDSImpact of high-intensity interval training, moderate-intensity continuous training, and resistance training on endothelial function in older adultsMed Sci Sport Exerc2020521057106710.1249/MSS.00000000000022261:CAS:528:DC%2BB3cXntl2ktbw%3D
HoffmannKSobolNAFrederiksenKSBeyerNVogelAVestergaardKModerate-to-high intensity physical exercise in patients with Alzheimer’s disease: a randomized controlled trialJ Alzheimers Dis.20155044345310.3233/JAD-150817
AngadiSSMookadamFLeeCDTuckerWJHaykowskyMJGaesserGAHigh-intensity interval training vs. moderate-intensity continuous exercise training in heart failure with preserved ejection fraction: a pilot studyJ Appl Physiol20151197537581:CAS:528:DC%2BC28XltV2kt7k%3D2519073910.1152/japplphysiol.00518.201425190739
WindsorMTBaileyTGPerissiouMGreavesKJhaPLeichtASAcute inflammatory responses to exercise in patients with abdominal aortic aneurysmMed Sci Sport Exerc20185064965810.1249/MSS.0000000000001501
CurrieKDMcKelvieRSMJMDFlow-mediated dilation is acutely improved after high-intensity interval exerciseMed Sci Sport Exerc2012442057206410.1249/MSS.0b013e318260ff92
MaillardFRoussetSPereiraBTraoreAde Pradel Del AmazePBoirieYHigh-intensity interval training reduces abdominal fat mass in postmenopausal women with type 2 diabetesDiabetes Metab20164264334411:STN:280:DC%2BC2szkslCjsw%3D%3D10.1016/j.diabet.2016.07.0312756712527567125
WilliamsCJGurdBJBonafigliaJTVoisinSLiZHarveyNA multi-center comparison of O2peak trainability between interval training and moderate intensity continuous trainingFront Physiol2019101930804794637074610.3389/fphys.2019.00019
SmartNADiebergGGiallauriaFIntermittent versus continuous exercise training in chronic heart failure: a meta-analysisInt J Cardiol.2013166235235810.1016/j.ijcard.2011.10.0752210017922100179
BaileyTGPerissiouMWindsorMTSchulzeKNamMMageeRLeichtASGreenDJGreavesKGolledgeJAskewCDEffects of acute exercise on endothelial function in patients with abdominal aortic aneurysmAm J Physiol Circ Physiol20183141H19H301:CAS:528:DC%2BC1cXhslWmurzI10.1152/ajpheart.00344.2017
IellamoFCaminitiGSposatoBVitaleCMassaroMRosanoGVolterraniMEffect of high-intensity interval training versus moderate continuous training on 24-h blood pressure profile and insulin resistance in patients with chronic heart failureIntern Emerg Med.20149554755210.1007/s11739-013-0980-42385703623857036
AtellaVPiano MortariAKopinskaJBelottiFLapiFCricelliCTrends in age-related disease burden and healthcare utilizationAging Cell201918e128611:CAS:528:DC%2BC1cXitlentbbJ3048864110.1111/acel.1286130488641
U.S. Department of Health and Human Services. Physical activity guidelines for Americans. 2nd ed. U.S. Department of Health and Human Services, editor. Okla, Nurse. Washington, DC; 2018.
Mejías-PeñaYRodriguez-MiguelezPFernandez-GonzaloRMartínez-FlórezSAlmarMde PazJAEffects of aerobic training on markers of autophagy in the elderlyAge (Omaha)2016383310.1007/s11357-016-9897-y1:CAS:528:DC%2BC28XktVOhu7o%3D
RodríguezDAArbillagaABarberan-GarciaARamirez-SarmientoATorralbaYVilaróJGimeno-SantosEGeaJOrozco-LeviMRocaJMarcoEEffects of interval and continuous exercise training on autonomic cardiac function in COPD patientsClin Respir J.201610183891:CAS:528:DC%2BC28XpsFOlug%3D%3D10.1111/crj.121892504373425043734
VogelTLeprêtreP-MBrechatP-HLonsdorferEBenetosAKaltenbachGEffects of a short-term personalized intermittent work exercise program (IWEP) on maximal cardio-respiratory function and endurance parameters among healthy young and older seniorsJ Nutr Health Aging.201115109059111:STN:280:DC%2BC38%2Fnt1SisQ%3D%3D10.1007/s12603-011-0087-42215978122159781
OsukaYMatsubaraMHamasakiAHiramatsuYOhshimaHTanakaKDevelopment of low-volume, high-intensity, aerobic-type interval training for elderly Japanese men: a feasibility studyEur Rev Aging Phys Act2017141428855969557157810.1186/s11556-017-0184-4
Aboarrage JuniorAMTeixeiraCVLSdos SantosRNMachadoAFEvangelistaALRicaRLA high-intensity jump-based aquatic exercise program improves bone mineral density and functional fitness in postmenopausal womenRejuvenation Res2018215355402988681510.1089/rej.2018.206929886815
ReichertTKanitzACDelevattiRSBagatiniNCBarrosoBMLFMKContinuous and interval training programs using deep water running improves functional fitness and blood pressure in the older adultsAge (Omaha)2016382010.1007/s11357-016-9882-5
FiorelliCMCiolacEGSimieliLSilvaFAFernandesBChristofolettiGDifferential acute effect of high-intensity interval or continuous moderate exercise on cognition in individuals with Parkinson’s diseaseJ Phys Act Heal20191615716410.1123/jpah.2018-0189
BuchheitMLaursenPBHigh-Intensity Interval Training, Solutions to the Programming PuzzleSport Med.201343531333810.1007/s40279-013-0029-x
StockwellTBMcKeanMRBurkettBJResponse to constant and interval exercise protocols in the elderlyJ Exerc Physiol Online.2012153039
BoukabousIMarcotte-ChénardAAmamouTBoulayPBrochuMTessierDLow-volume high-intensity interval training versus moderate-intensity continuous training on body composition, cardiometabolic profile, and physical capacity in older womenJ Aging Phys Act2019278798893103430410.1123/japa.2018-030931034304
BrownBMFrostNRainey-SmithSRDoeckeJMarkovicSGordonNWeinbornMSohrabiHRLawsSMMartinsRNEricksonKIPeifferJJHigh-intensity exercise and cognitive function in cognitively normal older adults: a pilot randomised clinical trialAlzheimers Res Ther.20211313310.1186/s13195-021-00774-y335229617849126
KarlsenTAamotI-LHaykowskyMRognmoØHigh intensity interval training for maximizing health outcomesProg Cardiovasc Dis.2017601677710.1016/j.pcad.2017.03.0062838555628385556
GuiraudTJuneauMNigamAGaydaMMeyerPMekarySPaillardFBosquetLOptimization of high intensity interval exercise in coronary heart diseaseEur J Appl Physiol2010108473374010.1007/s00421-009-1287-z1991585919915859
MohammadiRFathiMHejaziKIlkhaniBThe effect of eight weeks high-intensity interval aerobic training on chimerin and visfatin in overweight menJ Phys Educ Sport Sci.201711200206
NederveenJPJoanisseSSéguinCMLBellKEBakerSKPhillipsSMThe effect of exercise mode on the acute response of satellite cells in old menActa Physiol.20152151771901:CAS:528:DC%2BC2MXhs1CntLvJ10.1111/apha.12601
Moore JL, Nordvik JE, Erichsen A, Rosseland I, Bø E, Hornby TG, et al. Implementation of high-intensity stepping training during inpatient stroke rehabilitation improves functional outcomes. Barkenaes T, Byhring M, Grimstad I, Haga M, Halvorsen J, Henderson C, Mbalilaki JA, Rimehaug SA, Saether K, Tomren T, Vergoossen K BH, editor. Stroke; 2020;51:563–570.
CapelláILBenito PeinadoPJBarriopedro MoroMIRevengaJBEstevesNKCalderón MonteroFJDetermining the ventilatory inter-threshold area in individuals with different endurance capacitiesApunt Med l’Esport.201853199919710.1016/j.apunts.2017.11.003
MitropoulosAGumberACrankHAkilMKlonizakis M. The effects of upper and lower limb exercise on the microvascular reactivity in limited cutaneous systemic sclerosis patientsArthritis Res Ther2018201121:STN:280:DC%2BC1Mbkt1GnsQ%3D%3D29871697598943510.1186/s13075-018-1605-0
Jaul E, Barron J. Age-related diseases and clinical and public health implications for the 85 years old and over population. Front Public Heal. 2017;5.
BartlettDBSlentzCAWillisLHHoseltonAHuebnerJLKrausVBMossJMuehlbauerMJSpielmannGMuoioDMKovesTRWuHHuffmanKMLordJMKrausWERejuvenation of neutrophil functions in association with reduced diabetes risk following ten weeks of low-volume high intensity interval walking in older adults with prediabetes – a pilot studyFront Immunol.2020117291:CAS:528:DC%2BB3cXitVWnu7jJ10.3389/fimmu.2020.00729324316987214668
WindsorMTBaileyTGPerissiouMMeitalLGolledgeJRussellFDCytokine responses to acute exercise in healthy older adults: the effect of cardiorespiratory fitnessFront Physiol2018920329599722586285410.3389/fphys.2018.00203
StØrenØHelgerudJSÆbØMEMSØBratland-SandaSUnhjemRJThe effect of age on the V˙O2max response to high-intensity interval trainingMed Sci Sport Exerc201749788510.1249/MSS.0000000000001070
BruseghiniPCalabriaETamEMilaneseCOliboniEPezzatoAEffects of eight weeks of aerobic interval training and of isoinertial resistance training on risk factors of cardiometabolic diseases and exercise capacity in healthy elderly subjectsOncotarget20156169981701526046575462728710.18632/oncotarget.4031
SosnerPGaydaMDupuyOGarzonMLemassonCGremeauxVAmbulatory blood pressure reduction following high-intensity interval exercise performed in water or dryland conditionJ Am Soc Hypertens2016104204282702657010.1016/j.jash.2016.02.01127026570
DonathLKurzERothRZahnerLFaudeODifferent ankle muscle coordination patterns and co-activation during quiet stance between young adults and seniors do not change after a bout of high intensity trainingBMC Geriatr2015151925888336440999510.1186/s12877-015-0017-0
KeatingSEJohnsonNAMielkeGICoombesJSA systematic review and meta-analysis of interval training versus moderate-intensity continuous training on
GA Tew (344_CR57) 2017; 104
K Isaksen (344_CR64) 2016; 48
A Pandey (344_CR75) 2017; 33
BJ Andonian (344_CR68) 2018; 20
KC Roberts (344_CR97) 2015; 35
JL Devin (344_CR77) 2019; 597
A Mitropoulos (344_CR81) 2018; 20
A Kovacevic (344_CR30) 2020; 45
K Nakajima (344_CR36) 2010; 31
I Boukabous (344_CR70) 2019; 27
344_CR94
F Iellamo (344_CR62) 2014; 9
344_CR96
Y Osuka (344_CR39) 2017; 14
J-K Yoo (344_CR46) 2017; 91
Ø Ellingsen (344_CR60) 2017; 135
C-L Hwang (344_CR28) 2016; 82
R Mohammadi (344_CR74) 2017; 11
Y Mejías-Peña (344_CR34) 2016; 38
JM Northey (344_CR82) 2019; 22
I Butt (344_CR88) 2008; 47
MJ Gibala (344_CR16) 2012; 590
P Sosner (344_CR56) 2016; 10
K Hoffmann (344_CR79) 2015; 50
NA Smart (344_CR89) 2013; 166
MS Hood (344_CR17) 2011; 43
MJ Stork (344_CR9) 2017; 11
T Karlsen (344_CR8) 2017; 60
IL Capellá (344_CR15) 2018; 53
RF Spee (344_CR66) 2020; 299
MT Windsor (344_CR44) 2018; 9
JM dos Santos (344_CR50) 2018; 21
SS Angadi (344_CR59) 2015; 119
CM Fiorelli (344_CR78) 2019; 16
DB Bartlett (344_CR69) 2020; 11
MW O’Brien (344_CR38) 2020; 52
J-F Nepveu (344_CR54) 2017; 31
SE Keating (344_CR92) 2017; 18
TG Bailey (344_CR20) 2017; 122
344_CR32
344_CR33
T Venckunas (344_CR42) 2019; 119
Z Yasar (344_CR41) 2019; 7
MT Windsor (344_CR58) 2018; 50
K Karstoft (344_CR72) 2017; 8
S Banerjee (344_CR76) 2017; 26
M Wewege (344_CR93) 2017; 18
Z Milanovic (344_CR90) 2015; 45
TB Stockwell (344_CR40) 2012; 15
JW Keogh (344_CR80) 2018; 6
DHJ Thijssen (344_CR67) 2019; 10
T Reichert (344_CR55) 2016; 38
344_CR65
J Helgerud (344_CR52) 2009; 106
K Isaksen (344_CR63) 2015; 22
PJJ Herrod (344_CR26) 2020
PJJ Herrod (344_CR27) 2020; 3
K Norton (344_CR14) 2010; 13
F Maillard (344_CR73) 2016; 42
CK Roberts (344_CR4) 2005; 98
EY Uc (344_CR85) 2014; 83
CJ Williams (344_CR91) 2019; 10
P Bruseghini (344_CR23) 2020; 17
KS Weston (344_CR7) 2014; 48
VL Wyckelsma (344_CR45) 2017; 5
TG Bailey (344_CR47) 2018; 314
344_CR53
JP Nederveen (344_CR37) 2015; 215
AM Aboarrage Junior (344_CR18) 2018; 21
H Arksey (344_CR10) 2005; 8
T Vogel (344_CR43) 2011; 15
T Guiraud (344_CR51) 2010; 108
H-K Kim (344_CR29) 2017; 49
V Atella (344_CR95) 2019; 18
KD Currie (344_CR48) 2012; 44
AK Rizk (344_CR83) 2015; 12
M Buchheit (344_CR86) 2013; 43
S Mekari (344_CR35) 2020; 10
KD Currie (344_CR49) 2013; 45
T Fu (344_CR61) 2013; 167
J Sundell (344_CR11) 2011; 2011
C-L Hwang (344_CR71) 2019; 116
DA Rodríguez (344_CR84) 2016; 10
344_CR1
344_CR2
L Vanhees (344_CR13) 2012; 19
S Adamson (344_CR19) 2019; 15
H Littbrand (344_CR12) 2006; 86
VS Coswig (344_CR24) 2020; 18
344_CR5
BM Brown (344_CR21) 2021; 13
MJ Gibala (344_CR6) 2014; 44
344_CR3
P Bruseghini (344_CR22) 2015; 6
L Donath (344_CR25) 2015; 15
Ø StØren (344_CR87) 2017; 49
R Krusnauskas (344_CR31) 2018; 2018
References_xml – reference: VenckunasTKrusnauskasRSnieckusAEimantasNBaranauskieneNSkurvydasAAcute effects of very low-volume high-intensity interval training on muscular fatigue and serum testosterone level vary according to age and training statusEur J Appl Physiol2019119172517331:STN:280:DC%2BB3M3jtlyksg%3D%3D3116524110.1007/s00421-019-04162-131165241
– reference: IellamoFCaminitiGSposatoBVitaleCMassaroMRosanoGVolterraniMEffect of high-intensity interval training versus moderate continuous training on 24-h blood pressure profile and insulin resistance in patients with chronic heart failureIntern Emerg Med.20149554755210.1007/s11739-013-0980-42385703623857036
– reference: StockwellTBMcKeanMRBurkettBJResponse to constant and interval exercise protocols in the elderlyJ Exerc Physiol Online.2012153039
– reference: BanerjeeSManleyKShawBLewisLCucatoGMillsRVigorous intensity aerobic interval exercise in bladder cancer patients prior to radical cystectomy: a feasibility randomised controlled trialSupport Care Cancer.201726151515232918180429181804
– reference: NortheyJMPumpaKLQuinlanCIkinATooheyKSmeeDJCognition in breast cancer survivors: a pilot study of interval and continuous exerciseJ Sci Med Sport2019225805853055492310.1016/j.jsams.2018.11.02630554923
– reference: McSween M-P, McMahon KL, Maguire K, Coombes JS, Rodriguez AD, Erickson KI, et al. The acute effects of different exercise intensities on associative novel word learning in healthy older adults: a randomized controlled trial. J Aging Phys Act. 2021. p. 1–14. https://doi.org/10.1123/japa.2020-0093. Online ahead of print.
– reference: Mejías-PeñaYRodriguez-MiguelezPFernandez-GonzaloRMartínez-FlórezSAlmarMde PazJAEffects of aerobic training on markers of autophagy in the elderlyAge (Omaha)2016383310.1007/s11357-016-9897-y1:CAS:528:DC%2BC28XktVOhu7o%3D
– reference: KovacevicAFenesiBPaolucciEHeiszJJThe effects of aerobic exercise intensity on memory in older adultsAppl Physiol Nutr Metab2020455916003166561010.1139/apnm-2019-049531665610
– reference: GibalaMJGillenJBPercivalMEPhysiological and health-related adaptations to low-volume interval training: influences of nutrition and sexSport Med.201444S212713710.1007/s40279-014-0259-6
– reference: United Nations, Department of Economic and Social Affairs PD. World population ageing 2019. New York; 2020;ST/ESA/SER.A/444.
– reference: UN General Assembly. 67th session, December 2012. Resolution A/RES/67/81.
– reference: VanheesLGeladasNHansenDKouidiENiebauerJReinerŽCornelissenVAdamopoulosSPrescottEBörjessonMBjarnason-WehrensBBjörnstadHHCohen-SolalAConraadsVCorradoDde SutterJDohertyPDoyleFDugmoreDEllingsenØFagardRGiadaFGielenSHagerAHalleMHeidbüchelHJegierAMazicSMcGeeHMellwigKPMendesMMezzaniAPattynNPellicciaAPiepoliMRauchBSchmidt-TrucksässATakkenTvan BuurenFVanuzzoDImportance of characteristics and modalities of physical activity and exercise in the management of cardiovascular health in individuals with cardiovascular risk factors: recommendations from the EACPR (Part II)Eur J Prev Cardiol.2012195100510331:STN:280:DC%2BC38nms1OgtA%3D%3D10.1177/17418267114309262263774122637741
– reference: YasarZDewhurstSHayesLDSports2019794652435010.3390/sports7040094
– reference: WindsorMTBaileyTGPerissiouMGreavesKJhaPLeichtASAcute inflammatory responses to exercise in patients with abdominal aortic aneurysmMed Sci Sport Exerc20185064965810.1249/MSS.0000000000001501
– reference: BrownBMFrostNRainey-SmithSRDoeckeJMarkovicSGordonNWeinbornMSohrabiHRLawsSMMartinsRNEricksonKIPeifferJJHigh-intensity exercise and cognitive function in cognitively normal older adults: a pilot randomised clinical trialAlzheimers Res Ther.20211313310.1186/s13195-021-00774-y335229617849126
– reference: NederveenJPJoanisseSSéguinCMLBellKEBakerSKPhillipsSMThe effect of exercise mode on the acute response of satellite cells in old menActa Physiol.20152151771901:CAS:528:DC%2BC2MXhs1CntLvJ10.1111/apha.12601
– reference: Moore JL, Nordvik JE, Erichsen A, Rosseland I, Bø E, Hornby TG, et al. Implementation of high-intensity stepping training during inpatient stroke rehabilitation improves functional outcomes. Barkenaes T, Byhring M, Grimstad I, Haga M, Halvorsen J, Henderson C, Mbalilaki JA, Rimehaug SA, Saether K, Tomren T, Vergoossen K BH, editor. Stroke; 2020;51:563–570.
– reference: YooJ-KPintoMMKimH-KHwangC-LLimJHandbergEMSex impacts the flow-mediated dilation response to acute aerobic exercise in older adultsExp Gerontol20179157632821641210.1016/j.exger.2017.02.06928216412
– reference: FiorelliCMCiolacEGSimieliLSilvaFAFernandesBChristofolettiGDifferential acute effect of high-intensity interval or continuous moderate exercise on cognition in individuals with Parkinson’s diseaseJ Phys Act Heal20191615716410.1123/jpah.2018-0189
– reference: ButtIShresthaBMTwo-hit hypothesis and multiple organ dysfunction syndromeJ Nepal Med Assoc20084782851:STN:280:DC%2BD1crisVGjtg%3D%3D10.31729/jnma.318B. M. Shrestha, Sheffield Kidney Institute, Herries Road, Sheffield, S5 7AU, United Kingdom. E-mail: shresthabm@doctors.net.uk: Nepal Medical Association (Exhibition Road, post box 189, Kathmandu, Nepal)
– reference: BartlettDBSlentzCAWillisLHHoseltonAHuebnerJLKrausVBMossJMuehlbauerMJSpielmannGMuoioDMKovesTRWuHHuffmanKMLordJMKrausWERejuvenation of neutrophil functions in association with reduced diabetes risk following ten weeks of low-volume high intensity interval walking in older adults with prediabetes – a pilot studyFront Immunol.2020117291:CAS:528:DC%2BB3cXitVWnu7jJ10.3389/fimmu.2020.00729324316987214668
– reference: Statistics Canada. Table 13-10-0466-01 Healthy aging indicators, Canadian Community Health Survey, Healthy Aging. 2010.
– reference: BuchheitMLaursenPBHigh-Intensity Interval Training, Solutions to the Programming PuzzleSport Med.201343531333810.1007/s40279-013-0029-x
– reference: NortonKNortonLSadgroveDPosition statement on physical activity and exercise intensity terminologyJ Sci Med Sport.201013549650210.1016/j.jsams.2009.09.0082000517020005170
– reference: RobertsKCRaoDPBennettTLLoukineLJayaramanGCPrevalence and patterns of chronic disease multimorbidity and associated determinants in CanadaHeal Promot Chronic Dis Prev Canada20153587941:STN:280:DC%2BC287lvFKqsA%3D%3D10.24095/hpcdp.35.6.01
– reference: NepveuJ-FThielATangAFungJLundbye-JensenJBoydLAA single bout of high-intensity interval training improves motor skill retention in individuals with strokeNeurorehabil Neural Repair2017317267352869164510.1177/154596831771826928691645
– reference: AdamsonSKavaliauskasMYamagishiTPhillipsSLorimerRBabrajJExtremely short duration sprint interval training improves vascular health in older adultsSport Sci Health.201915112313110.1007/s11332-018-0498-2
– reference: HelgerudJWangEMostiMPWiggenØNHoffJPlantar flexion training primes peripheral arterial disease patients for improvements in cardiac functionEur J Appl Physiol2009106220721510.1007/s00421-009-1011-z1923842519238425
– reference: BruseghiniPCalabriaETamEMilaneseCOliboniEPezzatoAEffects of eight weeks of aerobic interval training and of isoinertial resistance training on risk factors of cardiometabolic diseases and exercise capacity in healthy elderly subjectsOncotarget20156169981701526046575462728710.18632/oncotarget.4031
– reference: ReichertTKanitzACDelevattiRSBagatiniNCBarrosoBMLFMKContinuous and interval training programs using deep water running improves functional fitness and blood pressure in the older adultsAge (Omaha)2016382010.1007/s11357-016-9882-5
– reference: IsaksenKMunkPSValborglandTLarsenAIAerobic interval training in patients with heart failure and an implantable cardioverter defibrillator: a controlled study evaluating feasibility and effectEur J Prev Cardiol2015222963032440329510.1177/204748731351934524403295
– reference: Linares AM, Goncin N, Stuckey M, Burgomaster KA, Dogra S. Acute cardiopulmonary response to interval and continuous exercise in older adults. J Strength Cond Res. 2020. https://doi.org/10.1519/JSC.0000000000003933. Publish ahead of print.
– reference: RodríguezDAArbillagaABarberan-GarciaARamirez-SarmientoATorralbaYVilaróJGimeno-SantosEGeaJOrozco-LeviMRocaJMarcoEEffects of interval and continuous exercise training on autonomic cardiac function in COPD patientsClin Respir J.201610183891:CAS:528:DC%2BC28XpsFOlug%3D%3D10.1111/crj.121892504373425043734
– reference: HwangC-LLimJYooJ-KKimH-KHwangM-HHandbergEMEffect of all-extremity high-intensity interval training vs. moderate-intensity continuous training on aerobic fitness in middle-aged and older adults with type 2 diabetes: A randomized controlled trialExp Gerontol201911646533057671610.1016/j.exger.2018.12.01330576716
– reference: LittbrandHRosendahlELindelöfNLundin-OlssonLGustafsonYNybergLA high-intensity functional weight-bearing exercise program for older people dependent in activities of daily living and living in residential care facilities: evaluation of the applicability with focus on cognitive functionPhys Ther.200686448949810.1093/ptj/86.4.4891657966616579666
– reference: HerrodPJJLundJNPhillipsBETime-efficient physical activity interventions to reduce blood pressure in older adults: a randomised controlled trial2020EnglandAge Ageing
– reference: MilanovicZSporisGWestonMEffectiveness of high-intensity interval training (HIT) and continuous endurance training for VO2max Improvements: a systematic review and meta-analysis of controlled trialsSports Med201545146914812624301410.1007/s40279-015-0365-026243014
– reference: WestonKSWisløffUCoombesJSHigh-intensity interval training in patients with lifestyle-induced cardiometabolic disease: a systematic review and meta-analysisBr J Sports Med201448122712342414453110.1136/bjsports-2013-09257624144531
– reference: WewegeMvan den BergRWardREKeechAThe effects of high-intensity interval training vs. moderate-intensity continuous training on body composition in overweight and obese adults: a systematic review and meta-analysisObes Rev2017186356461:CAS:528:DC%2BC2sXntVOlt7o%3D2840163810.1111/obr.1253228401638
– reference: TewGABatterhamAMCollingKGrayJKerrKKothmannENawazSWestonMYatesDDanjouxGRandomized feasibility trial of high-intensity interval training before elective abdominal aortic aneurysm repairBr J Surg201710413179118011:STN:280:DC%2BC1M%2FmsFKrtg%3D%3D10.1002/bjs.106692899065128990651
– reference: StØrenØHelgerudJSÆbØMEMSØBratland-SandaSUnhjemRJThe effect of age on the V˙O2max response to high-intensity interval trainingMed Sci Sport Exerc201749788510.1249/MSS.0000000000001070
– reference: CoswigVSBarbalhoMRaiolRDel VecchioFBRamirez-CampilloRGentilPEffects of high vs moderate-intensity intermittent training on functionality, resting heart rate and blood pressure of elderly womenJ Transl Med.20201818810.1186/s12967-020-02261-8320664607027031
– reference: FuTWangC-HLinP-SHsuC-CCherngW-JHuangS-CLiuMHChiangCLWangJSAerobic interval training improves oxygen uptake efficiency by enhancing cerebral and muscular hemodynamics in patients with heart failureInt J Cardiol20131671415010.1016/j.ijcard.2011.11.0862219712022197120
– reference: ThijssenDHJBendaNMMKerstensTPSeegerJPHvan DijkAPJHopmanMTE12-week exercise training, independent of the type of exercise, attenuates endothelial ischaemia-reperfusion injury in heart failure patientsFront Physiol20191026430930798642876310.3389/fphys.2019.00264
– reference: VogelTLeprêtreP-MBrechatP-HLonsdorferEBenetosAKaltenbachGEffects of a short-term personalized intermittent work exercise program (IWEP) on maximal cardio-respiratory function and endurance parameters among healthy young and older seniorsJ Nutr Health Aging.201115109059111:STN:280:DC%2BC38%2Fnt1SisQ%3D%3D10.1007/s12603-011-0087-42215978122159781
– reference: Aboarrage JuniorAMTeixeiraCVLSdos SantosRNMachadoAFEvangelistaALRicaRLA high-intensity jump-based aquatic exercise program improves bone mineral density and functional fitness in postmenopausal womenRejuvenation Res2018215355402988681510.1089/rej.2018.206929886815
– reference: MaillardFRoussetSPereiraBTraoreAde Pradel Del AmazePBoirieYHigh-intensity interval training reduces abdominal fat mass in postmenopausal women with type 2 diabetesDiabetes Metab20164264334411:STN:280:DC%2BC2szkslCjsw%3D%3D10.1016/j.diabet.2016.07.0312756712527567125
– reference: Munch GW, Iepsen UW, Ryrsø CK, Rosenmeier JB, Pedersen BK, Mortensen SP. Effect of 6 weeks of high-intensity one-legged cycling on functional sympatholysis and ATP signaling in patients with heart failure. Am J Physiol Circ Physiol; 2017;314:ajpheart.00379.
– reference: WindsorMTBaileyTGPerissiouMMeitalLGolledgeJRussellFDCytokine responses to acute exercise in healthy older adults: the effect of cardiorespiratory fitnessFront Physiol2018920329599722586285410.3389/fphys.2018.00203
– reference: GuiraudTJuneauMNigamAGaydaMMeyerPMekarySPaillardFBosquetLOptimization of high intensity interval exercise in coronary heart diseaseEur J Appl Physiol2010108473374010.1007/s00421-009-1287-z1991585919915859
– reference: MohammadiRFathiMHejaziKIlkhaniBThe effect of eight weeks high-intensity interval aerobic training on chimerin and visfatin in overweight menJ Phys Educ Sport Sci.201711200206
– reference: RizkAKWardiniRChan-ThimEBaconSLLavoieKLPepinVAcute responses to exercise training and relationship with exercise adherence in moderate chronic obstructive pulmonary diseaseChron Respir Dis.201512432933910.1177/14799723155986912627250026272500
– reference: BaileyTGPerissiouMWindsorMRussellFGolledgeJGreenDJAskewCDCardiorespiratory fitness modulates the acute flow-mediated dilation response following high-intensity but not moderate-intensity exercise in elderly menJ Appl Physiol201712251238124810.1152/japplphysiol.00935.20162820974228209742
– reference: SosnerPGaydaMDupuyOGarzonMLemassonCGremeauxVAmbulatory blood pressure reduction following high-intensity interval exercise performed in water or dryland conditionJ Am Soc Hypertens2016104204282702657010.1016/j.jash.2016.02.01127026570
– reference: BoukabousIMarcotte-ChénardAAmamouTBoulayPBrochuMTessierDLow-volume high-intensity interval training versus moderate-intensity continuous training on body composition, cardiometabolic profile, and physical capacity in older womenJ Aging Phys Act2019278798893103430410.1123/japa.2018-030931034304
– reference: OsukaYMatsubaraMHamasakiAHiramatsuYOhshimaHTanakaKDevelopment of low-volume, high-intensity, aerobic-type interval training for elderly Japanese men: a feasibility studyEur Rev Aging Phys Act2017141428855969557157810.1186/s11556-017-0184-4
– reference: KimH-KHwangC-LYooJ-KHwangM-HHandbergEMPetersenJWAll-extremity exercise training improves arterial stiffness in older adultsMed Sci Sport Exerc20174971404141110.1249/MSS.0000000000001229
– reference: HwangC-LYooJ-KKimH-KHwangM-HHandbergEMPetersenJWNovel all-extremity high-intensity interval training improves aerobic fitness, cardiac function and insulin resistance in healthy older adultsExp Gerontol2016821121191:CAS:528:DC%2BC28XhtFWhtrnL27346646497515410.1016/j.exger.2016.06.009
– reference: KrusnauskasRVenckunasTSnieckusAEimantasNBaranauskieneNSkurvydasABrazaitisMLiubinskieneAKamandulisSVery low volume high-intensity interval exercise is more effective in young than old womenBiomed Res Int20182018191:CAS:528:DC%2BC1cXitl2ls73F10.1155/2018/8913187
– reference: IsaksenKMunkPGiskeRLarsenAEffects of aerobic interval training on measures of anxiety, depression and quality of life in patients with ischaemic heart failure and an implantable cardioverter defibrillator: a prospective non-randomized trialJ Rehabil Med. Sweden201648330030610.2340/16501977-2043
– reference: PandeyASuskinNPoirierPThe impact of burst exercise on cardiometabolic status of patients newly diagnosed with type 2 diabetesCan J Cardiol.201733121645165110.1016/j.cjca.2017.09.0192917360429173604
– reference: EllingsenØHalleMConraadsVStøylenADalenHDelagardelleCLarsenAIHoleTMezzaniAvan CraenenbroeckEVidemVBeckersPChristleJWWinzerEMangnerNWoitekFHöllriegelRPresslerAMonk-HansenTSnoerMFeiereisenPValborglandTKjekshusJHambrechtRGielenSKarlsenTPrescottELinkeASMARTEX Heart Failure Study (Study of Myocardial Recovery After Exercise Training in Heart Failure) GroupHigh-intensity interval training in patients with heart failure with reduced ejection fractionCirculation2017135983984910.1161/CIRCULATIONAHA.116.022924280823875325251
– reference: U.S. Department of Health and Human Services. Physical activity guidelines for Americans. 2nd ed. U.S. Department of Health and Human Services, editor. Okla, Nurse. Washington, DC; 2018.
– reference: MitropoulosAGumberACrankHAkilMKlonizakis M. The effects of upper and lower limb exercise on the microvascular reactivity in limited cutaneous systemic sclerosis patientsArthritis Res Ther2018201121:STN:280:DC%2BC1Mbkt1GnsQ%3D%3D29871697598943510.1186/s13075-018-1605-0
– reference: AngadiSSMookadamFLeeCDTuckerWJHaykowskyMJGaesserGAHigh-intensity interval training vs. moderate-intensity continuous exercise training in heart failure with preserved ejection fraction: a pilot studyJ Appl Physiol20151197537581:CAS:528:DC%2BC28XltV2kt7k%3D2519073910.1152/japplphysiol.00518.201425190739
– reference: RobertsCKBarnardRJEffects of exercise and diet on chronic diseaseJ Appl Physiol.200598133010.1152/japplphysiol.00852.20041559130015591300
– reference: AndonianBJBartlettDBHuebnerJLWillisLHoseltonAKrausVBKrausWEHuffmanKMEffect of high-intensity interval training on muscle remodeling in rheumatoid arthritis compared to prediabetesArthritis Res Ther.20182012831:CAS:528:DC%2BC1MXit1yhsb8%3D10.1186/s13075-018-1786-6305872306307310
– reference: MekariSNeyedliHFFraserSO’BrienMWMartinsREvansKEarleMAucoinRChiekweJHollohanQKimmerlyDSDupuyOHigh-intensity interval training improves cognitive flexibility in older adultsBrain Sci.2020101179610.3390/brainsci101107967693870
– reference: KeoghJWGriggJVertulloCJIs high-intensity interval cycling feasible and more beneficial than continuous cycling for knee osteoarthritic patients? Results of a randomised control feasibility trialPeerJ20186e473829761054594905610.7717/peerj.4738
– reference: CapelláILBenito PeinadoPJBarriopedro MoroMIRevengaJBEstevesNKCalderón MonteroFJDetermining the ventilatory inter-threshold area in individuals with different endurance capacitiesApunt Med l’Esport.201853199919710.1016/j.apunts.2017.11.003
– reference: ArkseyHO’MalleyLScoping studies: towards a methodological frameworkInt J Soc Res Methodol.200581193210.1080/1364557032000119616
– reference: WilliamsCJGurdBJBonafigliaJTVoisinSLiZHarveyNA multi-center comparison of O2peak trainability between interval training and moderate intensity continuous trainingFront Physiol2019101930804794637074610.3389/fphys.2019.00019
– reference: Jaul E, Barron J. Age-related diseases and clinical and public health implications for the 85 years old and over population. Front Public Heal. 2017;5.
– reference: HoodMSLittleJPTarnopolskyMAMyslikFGibalaMJLow-volume interval training improves muscle oxidative capacity in sedentary adultsMed Sci Sport Exerc.20114310184918561:CAS:528:DC%2BC3MXhtF2jtr%2FF10.1249/MSS.0b013e3182199834
– reference: Prince MJ, Wu F, Guo Y, Gutierrez Robledo LM, O’Donnell M, Sullivan R, et al. The burden of disease in older people and implications for health policy and practice. Lancet. 2015;385(9967):549-62. https://doi.org/10.1016/S0140-6736(14)61347-7. Epub 2014 Nov 6.
– reference: CurrieKDDubberleyJBMcKelvieRSMacdonald. MJ. Low-volume, high-intensity interval training in patients with CADMed Sci Sport Exerc2013451436144210.1249/MSS.0b013e31828bbbd4
– reference: HoffmannKSobolNAFrederiksenKSBeyerNVogelAVestergaardKModerate-to-high intensity physical exercise in patients with Alzheimer’s disease: a randomized controlled trialJ Alzheimers Dis.20155044345310.3233/JAD-150817
– reference: SpeeRFNiemeijerVMSchootsTTuinenburgAHouthuizenPWijnPFDoevendansPAKempsHMHigh intensity interval training after cardiac resynchronization therapy: An explorative randomized controlled trialInt J Cardiol.202029916917410.1016/j.ijcard.2019.07.0233135315831353158
– reference: GibalaMJLittleJPMacDonaldMJHawleyJAReply from M. J. Gibala, J. P. Little, M. J. MadDonald and J. A. HawleyJ Physiol201259033911:CAS:528:DC%2BC38Xht1Oks7bE345905110.1113/jphysiol.2012.235127
– reference: HerrodPJJBlackwellJEMBoereboomCLAthertonPJWilliamsJPLundJNPhillipsBEThe time course of physiological adaptations to high-intensity interval training in older adultsAging Med20203424525110.1002/agm2.12127
– reference: dos SantosJMGouveiaMCde Souza JúniorFAda Silva RodriguesCEdos SantosJMde OliveiraAJSEffect of a high-intensity interval training session on post-exercise hypotension and autonomic cardiac activity in hypertensive elderly subjectsJ Exerc Physiol Online.2018215870
– reference: KarstoftKBrinkløvCFThorsenIKNielsenJSRied-LarsenMResting metabolic rate does not change in response to different types of training in subjects with type 2 diabetesFront Endocrinol (Lausanne)2017813210.3389/fendo.2017.00132
– reference: BruseghiniPTamECalabriaEMilaneseCCapelliCGalvaniCHigh intensity interval training does not have compensatory effects on physical activity levels in older adultsInt J Environ Res Public Health.2020173108310.3390/ijerph170310837037169
– reference: DonathLKurzERothRZahnerLFaudeODifferent ankle muscle coordination patterns and co-activation during quiet stance between young adults and seniors do not change after a bout of high intensity trainingBMC Geriatr2015151925888336440999510.1186/s12877-015-0017-0
– reference: NakajimaKTakeokaMMoriMHashimotoSSakuraiANoseHHiguchiKItanoNShioharaMOhTTaniguchiSExercise effects on methylation of ASC geneInt J Sports Med.201031096716751:CAS:528:DC%2BC3cXhtlemsrbK10.1055/s-0029-12461402020080320200803
– reference: SmartNADiebergGGiallauriaFIntermittent versus continuous exercise training in chronic heart failure: a meta-analysisInt J Cardiol.2013166235235810.1016/j.ijcard.2011.10.0752210017922100179
– reference: KeatingSEJohnsonNAMielkeGICoombesJSA systematic review and meta-analysis of interval training versus moderate-intensity continuous training on body adiposityObes Rev2017189439641:STN:280:DC%2BC1crotFKnsA%3D%3D2851310310.1111/obr.1253628513103
– reference: O’BrienMWJohnsJARobinsonSABungayAMekarySKimmerlyDSImpact of high-intensity interval training, moderate-intensity continuous training, and resistance training on endothelial function in older adultsMed Sci Sport Exerc2020521057106710.1249/MSS.00000000000022261:CAS:528:DC%2BB3cXntl2ktbw%3D
– reference: StorkMJBanfieldLEGibalaMJMartin GinisKAA scoping review of the psychological responses to interval exercise: is interval exercise a viable alternative to traditional exercise?Health Psychol Rev2017113243442846060110.1080/17437199.2017.132601128460601
– reference: CurrieKDMcKelvieRSMJMDFlow-mediated dilation is acutely improved after high-intensity interval exerciseMed Sci Sport Exerc2012442057206410.1249/MSS.0b013e318260ff92
– reference: DevinJLHillMMMourtzakisMQuadrilateroJJenkinsDGSkinnerTLAcute high intensity interval exercise reduces colon cancer cell growthJ Physiol.20195978217721841:CAS:528:DC%2BC1MXlsFers7c%3D10.1113/JP277648308120596462486
– reference: WyckelsmaVLLevingerIMurphyRMPetersenACPerryBDHedgesCPIntense interval training in healthy older adults increases skeletal muscle [3H]ouabain-binding site content and elevates Na+,K+-ATPase α2 isoform abundance in type II fibersPhysiol Rep20175e1321928373411539251110.14814/phy2.132191:CAS:528:DC%2BC2sXmtFCmt78%3D
– reference: AtellaVPiano MortariAKopinskaJBelottiFLapiFCricelliCTrends in age-related disease burden and healthcare utilizationAging Cell201918e128611:CAS:528:DC%2BC1cXitlentbbJ3048864110.1111/acel.1286130488641
– reference: UcEYDoerschugKCMagnottaVDawsonJDThomsenTRKlineJNRizzoMNewmanSRMehtaSGrabowskiTJBrussJBlanchetteDRAndersonSWVossMWKramerAFDarlingWGPhase I/II randomized trial of aerobic exercise in Parkinson disease in a community settingNeurology.201483541342510.1212/WNL.0000000000000644249910374132568
– reference: KarlsenTAamotI-LHaykowskyMRognmoØHigh intensity interval training for maximizing health outcomesProg Cardiovasc Dis.2017601677710.1016/j.pcad.2017.03.0062838555628385556
– reference: SundellJResistance training is an effective tool against metabolic and frailty syndromesAdv Prev Med.201120111710.4061/2011/984683
– reference: BaileyTGPerissiouMWindsorMTSchulzeKNamMMageeRLeichtASGreenDJGreavesKGolledgeJAskewCDEffects of acute exercise on endothelial function in patients with abdominal aortic aneurysmAm J Physiol Circ Physiol20183141H19H301:CAS:528:DC%2BC1cXhslWmurzI10.1152/ajpheart.00344.2017
– volume: 8
  start-page: 19
  issue: 1
  year: 2005
  ident: 344_CR10
  publication-title: Int J Soc Res Methodol.
  doi: 10.1080/1364557032000119616
– volume: 17
  start-page: 1083
  issue: 3
  year: 2020
  ident: 344_CR23
  publication-title: Int J Environ Res Public Health.
  doi: 10.3390/ijerph17031083
– volume: 22
  start-page: 580
  year: 2019
  ident: 344_CR82
  publication-title: J Sci Med Sport
  doi: 10.1016/j.jsams.2018.11.026
– volume: 19
  start-page: 1005
  issue: 5
  year: 2012
  ident: 344_CR13
  publication-title: Eur J Prev Cardiol.
  doi: 10.1177/1741826711430926
– ident: 344_CR33
  doi: 10.1123/japa.2020-0093
– volume: 27
  start-page: 879
  year: 2019
  ident: 344_CR70
  publication-title: J Aging Phys Act
  doi: 10.1123/japa.2018-0309
– volume: 43
  start-page: 1849
  issue: 10
  year: 2011
  ident: 344_CR17
  publication-title: Med Sci Sport Exerc.
  doi: 10.1249/MSS.0b013e3182199834
– volume: 11
  start-page: 729
  year: 2020
  ident: 344_CR69
  publication-title: Front Immunol.
  doi: 10.3389/fimmu.2020.00729
– ident: 344_CR53
  doi: 10.1161/STROKEAHA.119.027450
– volume: 10
  start-page: 264
  year: 2019
  ident: 344_CR67
  publication-title: Front Physiol
  doi: 10.3389/fphys.2019.00264
– volume: 6
  start-page: e4738
  year: 2018
  ident: 344_CR80
  publication-title: PeerJ
  doi: 10.7717/peerj.4738
– ident: 344_CR94
  doi: 10.3389/fpubh.2017.00335
– volume: 45
  start-page: 1469
  year: 2015
  ident: 344_CR90
  publication-title: Sports Med
  doi: 10.1007/s40279-015-0365-0
– volume: 86
  start-page: 489
  issue: 4
  year: 2006
  ident: 344_CR12
  publication-title: Phys Ther.
  doi: 10.1093/ptj/86.4.489
– volume: 49
  start-page: 1404
  issue: 7
  year: 2017
  ident: 344_CR29
  publication-title: Med Sci Sport Exerc
  doi: 10.1249/MSS.0000000000001229
– volume: 18
  start-page: 88
  issue: 1
  year: 2020
  ident: 344_CR24
  publication-title: J Transl Med.
  doi: 10.1186/s12967-020-02261-8
– volume: 52
  start-page: 1057
  year: 2020
  ident: 344_CR38
  publication-title: Med Sci Sport Exerc
  doi: 10.1249/MSS.0000000000002226
– volume: 106
  start-page: 207
  issue: 2
  year: 2009
  ident: 344_CR52
  publication-title: Eur J Appl Physiol
  doi: 10.1007/s00421-009-1011-z
– volume: 38
  start-page: 20
  year: 2016
  ident: 344_CR55
  publication-title: Age (Omaha)
  doi: 10.1007/s11357-016-9882-5
– volume: 9
  start-page: 547
  issue: 5
  year: 2014
  ident: 344_CR62
  publication-title: Intern Emerg Med.
  doi: 10.1007/s11739-013-0980-4
– volume: 104
  start-page: 1791
  issue: 13
  year: 2017
  ident: 344_CR57
  publication-title: Br J Surg
  doi: 10.1002/bjs.10669
– volume: 15
  start-page: 19
  year: 2015
  ident: 344_CR25
  publication-title: BMC Geriatr
  doi: 10.1186/s12877-015-0017-0
– volume: 119
  start-page: 1725
  year: 2019
  ident: 344_CR42
  publication-title: Eur J Appl Physiol
  doi: 10.1007/s00421-019-04162-1
– volume: 3
  start-page: 245
  issue: 4
  year: 2020
  ident: 344_CR27
  publication-title: Aging Med
  doi: 10.1002/agm2.12127
– volume: 49
  start-page: 78
  year: 2017
  ident: 344_CR87
  publication-title: Med Sci Sport Exerc
  doi: 10.1249/MSS.0000000000001070
– volume: 44
  start-page: 127
  issue: S2
  year: 2014
  ident: 344_CR6
  publication-title: Sport Med.
  doi: 10.1007/s40279-014-0259-6
– volume: 16
  start-page: 157
  year: 2019
  ident: 344_CR78
  publication-title: J Phys Act Heal
  doi: 10.1123/jpah.2018-0189
– ident: 344_CR5
– ident: 344_CR65
  doi: 10.1152/ajpheart.00379.2017
– volume: 167
  start-page: 41
  issue: 1
  year: 2013
  ident: 344_CR61
  publication-title: Int J Cardiol
  doi: 10.1016/j.ijcard.2011.11.086
– volume: 43
  start-page: 313
  issue: 5
  year: 2013
  ident: 344_CR86
  publication-title: Sport Med.
  doi: 10.1007/s40279-013-0029-x
– volume: 122
  start-page: 1238
  issue: 5
  year: 2017
  ident: 344_CR20
  publication-title: J Appl Physiol
  doi: 10.1152/japplphysiol.00935.2016
– volume: 45
  start-page: 1436
  year: 2013
  ident: 344_CR49
  publication-title: Med Sci Sport Exerc
  doi: 10.1249/MSS.0b013e31828bbbd4
– volume: 10
  start-page: 19
  year: 2019
  ident: 344_CR91
  publication-title: Front Physiol
  doi: 10.3389/fphys.2019.00019
– volume: 135
  start-page: 839
  issue: 9
  year: 2017
  ident: 344_CR60
  publication-title: Circulation
  doi: 10.1161/CIRCULATIONAHA.116.022924
– volume: 8
  start-page: 132
  year: 2017
  ident: 344_CR72
  publication-title: Front Endocrinol (Lausanne)
  doi: 10.3389/fendo.2017.00132
– volume: 15
  start-page: 123
  issue: 1
  year: 2019
  ident: 344_CR19
  publication-title: Sport Sci Health.
  doi: 10.1007/s11332-018-0498-2
– volume: 2011
  start-page: 1
  year: 2011
  ident: 344_CR11
  publication-title: Adv Prev Med.
  doi: 10.4061/2011/984683
– volume: 26
  start-page: 1515
  year: 2017
  ident: 344_CR76
  publication-title: Support Care Cancer.
– volume: 21
  start-page: 58
  year: 2018
  ident: 344_CR50
  publication-title: J Exerc Physiol Online.
– volume: 13
  start-page: 496
  issue: 5
  year: 2010
  ident: 344_CR14
  publication-title: J Sci Med Sport.
  doi: 10.1016/j.jsams.2009.09.008
– ident: 344_CR32
  doi: 10.1519/JSC.0000000000003933
– ident: 344_CR2
  doi: 10.1016/S0140-6736(14)61347-7
– volume: 10
  start-page: 420
  year: 2016
  ident: 344_CR56
  publication-title: J Am Soc Hypertens
  doi: 10.1016/j.jash.2016.02.011
– volume: 48
  start-page: 300
  issue: 3
  year: 2016
  ident: 344_CR64
  publication-title: J Rehabil Med. Sweden
  doi: 10.2340/16501977-2043
– volume: 9
  start-page: 203
  year: 2018
  ident: 344_CR44
  publication-title: Front Physiol
  doi: 10.3389/fphys.2018.00203
– volume: 6
  start-page: 16998
  year: 2015
  ident: 344_CR22
  publication-title: Oncotarget
  doi: 10.18632/oncotarget.4031
– volume: 38
  start-page: 33
  year: 2016
  ident: 344_CR34
  publication-title: Age (Omaha)
  doi: 10.1007/s11357-016-9897-y
– volume: 11
  start-page: 200
  year: 2017
  ident: 344_CR74
  publication-title: J Phys Educ Sport Sci.
– volume: 33
  start-page: 1645
  issue: 12
  year: 2017
  ident: 344_CR75
  publication-title: Can J Cardiol.
  doi: 10.1016/j.cjca.2017.09.019
– volume: 21
  start-page: 535
  year: 2018
  ident: 344_CR18
  publication-title: Rejuvenation Res
  doi: 10.1089/rej.2018.2069
– volume: 50
  start-page: 443
  year: 2015
  ident: 344_CR79
  publication-title: J Alzheimers Dis.
  doi: 10.3233/JAD-150817
– volume: 31
  start-page: 671
  issue: 09
  year: 2010
  ident: 344_CR36
  publication-title: Int J Sports Med.
  doi: 10.1055/s-0029-1246140
– volume: 108
  start-page: 733
  issue: 4
  year: 2010
  ident: 344_CR51
  publication-title: Eur J Appl Physiol
  doi: 10.1007/s00421-009-1287-z
– volume: 116
  start-page: 46
  year: 2019
  ident: 344_CR71
  publication-title: Exp Gerontol
  doi: 10.1016/j.exger.2018.12.013
– volume: 91
  start-page: 57
  year: 2017
  ident: 344_CR46
  publication-title: Exp Gerontol
  doi: 10.1016/j.exger.2017.02.069
– volume: 13
  start-page: 33
  issue: 1
  year: 2021
  ident: 344_CR21
  publication-title: Alzheimers Res Ther.
  doi: 10.1186/s13195-021-00774-y
– volume: 119
  start-page: 753
  year: 2015
  ident: 344_CR59
  publication-title: J Appl Physiol
  doi: 10.1152/japplphysiol.00518.2014
– volume: 18
  start-page: 635
  year: 2017
  ident: 344_CR93
  publication-title: Obes Rev
  doi: 10.1111/obr.12532
– volume: 22
  start-page: 296
  year: 2015
  ident: 344_CR63
  publication-title: Eur J Prev Cardiol
  doi: 10.1177/2047487313519345
– volume: 11
  start-page: 324
  year: 2017
  ident: 344_CR9
  publication-title: Health Psychol Rev
  doi: 10.1080/17437199.2017.1326011
– ident: 344_CR3
– volume: 15
  start-page: 30
  year: 2012
  ident: 344_CR40
  publication-title: J Exerc Physiol Online.
– volume: 20
  start-page: 112
  year: 2018
  ident: 344_CR81
  publication-title: Arthritis Res Ther
  doi: 10.1186/s13075-018-1605-0
– volume: 47
  start-page: 82
  year: 2008
  ident: 344_CR88
  publication-title: J Nepal Med Assoc
  doi: 10.31729/jnma.318
– volume: 5
  start-page: e13219
  year: 2017
  ident: 344_CR45
  publication-title: Physiol Rep
  doi: 10.14814/phy2.13219
– volume: 590
  start-page: 3391
  year: 2012
  ident: 344_CR16
  publication-title: J Physiol
  doi: 10.1113/jphysiol.2012.235127
– volume: 35
  start-page: 87
  year: 2015
  ident: 344_CR97
  publication-title: Heal Promot Chronic Dis Prev Canada
  doi: 10.24095/hpcdp.35.6.01
– volume: 42
  start-page: 433
  issue: 6
  year: 2016
  ident: 344_CR73
  publication-title: Diabetes Metab
  doi: 10.1016/j.diabet.2016.07.031
– volume: 12
  start-page: 329
  issue: 4
  year: 2015
  ident: 344_CR83
  publication-title: Chron Respir Dis.
  doi: 10.1177/1479972315598691
– volume: 597
  start-page: 2177
  issue: 8
  year: 2019
  ident: 344_CR77
  publication-title: J Physiol.
  doi: 10.1113/JP277648
– volume: 98
  start-page: 3
  issue: 1
  year: 2005
  ident: 344_CR4
  publication-title: J Appl Physiol.
  doi: 10.1152/japplphysiol.00852.2004
– ident: 344_CR96
– volume: 48
  start-page: 1227
  year: 2014
  ident: 344_CR7
  publication-title: Br J Sports Med
  doi: 10.1136/bjsports-2013-092576
– volume: 50
  start-page: 649
  year: 2018
  ident: 344_CR58
  publication-title: Med Sci Sport Exerc
  doi: 10.1249/MSS.0000000000001501
– volume: 20
  start-page: 283
  issue: 1
  year: 2018
  ident: 344_CR68
  publication-title: Arthritis Res Ther.
  doi: 10.1186/s13075-018-1786-6
– volume: 45
  start-page: 591
  year: 2020
  ident: 344_CR30
  publication-title: Appl Physiol Nutr Metab
  doi: 10.1139/apnm-2019-0495
– volume: 215
  start-page: 177
  year: 2015
  ident: 344_CR37
  publication-title: Acta Physiol.
  doi: 10.1111/apha.12601
– volume: 31
  start-page: 726
  year: 2017
  ident: 344_CR54
  publication-title: Neurorehabil Neural Repair
  doi: 10.1177/1545968317718269
– volume: 314
  start-page: H19
  issue: 1
  year: 2018
  ident: 344_CR47
  publication-title: Am J Physiol Circ Physiol
  doi: 10.1152/ajpheart.00344.2017
– volume: 166
  start-page: 352
  issue: 2
  year: 2013
  ident: 344_CR89
  publication-title: Int J Cardiol.
  doi: 10.1016/j.ijcard.2011.10.075
– volume: 18
  start-page: 943
  year: 2017
  ident: 344_CR92
  publication-title: Obes Rev
  doi: 10.1111/obr.12536
– volume: 60
  start-page: 67
  issue: 1
  year: 2017
  ident: 344_CR8
  publication-title: Prog Cardiovasc Dis.
  doi: 10.1016/j.pcad.2017.03.006
– volume: 53
  start-page: 91
  issue: 199
  year: 2018
  ident: 344_CR15
  publication-title: Apunt Med l’Esport.
  doi: 10.1016/j.apunts.2017.11.003
– volume: 15
  start-page: 905
  issue: 10
  year: 2011
  ident: 344_CR43
  publication-title: J Nutr Health Aging.
  doi: 10.1007/s12603-011-0087-4
– ident: 344_CR1
– volume: 18
  start-page: e12861
  year: 2019
  ident: 344_CR95
  publication-title: Aging Cell
  doi: 10.1111/acel.12861
– volume: 299
  start-page: 169
  year: 2020
  ident: 344_CR66
  publication-title: Int J Cardiol.
  doi: 10.1016/j.ijcard.2019.07.023
– volume: 10
  start-page: 796
  issue: 11
  year: 2020
  ident: 344_CR35
  publication-title: Brain Sci.
  doi: 10.3390/brainsci10110796
– volume: 7
  start-page: 94
  year: 2019
  ident: 344_CR41
  publication-title: Sports
  doi: 10.3390/sports7040094
– volume: 83
  start-page: 413
  issue: 5
  year: 2014
  ident: 344_CR85
  publication-title: Neurology.
  doi: 10.1212/WNL.0000000000000644
– volume: 44
  start-page: 2057
  year: 2012
  ident: 344_CR48
  publication-title: Med Sci Sport Exerc
  doi: 10.1249/MSS.0b013e318260ff92
– volume: 82
  start-page: 112
  year: 2016
  ident: 344_CR28
  publication-title: Exp Gerontol
  doi: 10.1016/j.exger.2016.06.009
– volume: 10
  start-page: 83
  issue: 1
  year: 2016
  ident: 344_CR84
  publication-title: Clin Respir J.
  doi: 10.1111/crj.12189
– volume: 2018
  start-page: 1
  year: 2018
  ident: 344_CR31
  publication-title: Biomed Res Int
  doi: 10.1155/2018/8913187
– volume-title: Time-efficient physical activity interventions to reduce blood pressure in older adults: a randomised controlled trial
  year: 2020
  ident: 344_CR26
– volume: 14
  start-page: 14
  year: 2017
  ident: 344_CR39
  publication-title: Eur Rev Aging Phys Act
  doi: 10.1186/s11556-017-0184-4
SSID ssib050444303
ssj0001537409
Score 2.4203806
SecondaryResourceType review_article
Snippet High-intensity interval training (HIIT) is an increasingly popular form of aerobic exercise which includes bouts of high-intensity exercise interspersed with...
SourceID pubmedcentral
proquest
pubmed
crossref
springer
SourceType Open Access Repository
Aggregation Database
Index Database
Enrichment Source
Publisher
StartPage 49
SubjectTerms Exercise
Interval training
Medicine
Medicine & Public Health
Older people
Review
Review Article
Sports Medicine
SummonAdditionalLinks – databaseName: ProQuest Central
  dbid: BENPR
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3NS8MwFH_ovHgRxa_qlBy8aXBt0qTxIptMhuAHfoC3kjYNCtJNWw_-9yZpujGHOzdtw3sveR95-f0ATnTCpSSFwhnXBBuPr7BQMsJKMUGojqJc2UTx9o6NXujNa_zqC26Vb6ts90S3Uatxbmvk5yb0JcYZC5JcTj6xZY2yp6ueQmMV1swWnCQdWBsM7x4eZ1WWmHDq-jzMyhTY0qy0N2cSdl6ZbMbeMItMRm2h7zCd904LIedi5-Sf41Pnla43YcOHk6jf6H8LVopyGwa2eQP75vT6B7mqn7Eo9Oz5INB7ie4tPTfqW_iN6gJJ9JS7q1OoOSzYgZfr4fPVCHuuBJzHXNQ4jFSmXPlCUsF4T1NRUC6ZSXBpTDNNVNIjmoaKm4eyp-OoYJKEWhUF0z2hyC50ynFZ7AMyMuIqJFqqWFKaE8kk45mwqDEq0aEMIGxllOYeSNzyWXykLqFIWNrINTVyTZ1cUxrA6fSdSQOjsXR0txV96pdUlc4MIIC9RgvTTxEacRNXxQHwOf1MB1gQ7fkn5fubA9N2GWccBnDWanL2y_9neLB8hoewHlmrcm0vXejUX9_FkQle6uzYW-gv81jp2g
  priority: 102
  providerName: ProQuest
– databaseName: Springer Journals Complete - Open Access
  dbid: C24
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV1LS8QwEB50BfEivq2ukoM3DW6bV-ttFZdFWD24C3sradPgglSx9eC_N0nTXdYXeG6ahplJM19m5huAMx0LKUmhcCY0webEVzhRMsJK8YRQHUW5skBxdM-HE3o3ZVNfFFa12e5tSNL9qd22jvllZaCHLQeLDPy1PHWYrsIas9jdhmgXnOPMMqARH1tsaoWJoC7Xw-zOBNtWK231zI_TLp9Q39zO79mTX0Ko7mQabMGmdylRv7GBbVgpyh1YH_mg-S5c21wO7HPV6w_kLgGNgaGxbw-BZiV6sN26Ud-ycVRXSKLH3FVSoSZ2sAeTwe34Zoh96wScM5HUOIxUptxthqQJFz1Nk4IKyQ3epYxmmqi4RzQNlTAPZU-zqOCShFoVBde9RJF96JQvZXEIyIhLqJBoqZikNCeSSy6yxJLIqFiHMoCwFVeae15x297iOXX4IuZpI-LUiDh1Ik5pAOfzd14bVo0_R3dbLaR-h1WpgULEOGdmHQEcNAqZT0VoJIybxQIQS6qaD7Cc2stPytmT49Z2AJSFAVy0Sl188vcVHv1v-DFsRNbgXFZMFzr123txYnybOjt1pvwJd5br8w
  priority: 102
  providerName: Springer Nature
Title High-Intensity Interval Training in Older Adults: a Scoping Review
URI https://link.springer.com/article/10.1186/s40798-021-00344-4
https://www.ncbi.nlm.nih.gov/pubmed/34279765
https://www.proquest.com/docview/2553125938
https://pubmed.ncbi.nlm.nih.gov/PMC8289951
Volume 7
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV1LS8QwEB58XLyI4qs-lhy8aXSbpEkriOiiiLCrqAveSto0uCD1sSvov3eStivrC7z0kjRNJxNmvmRmPoBtGyuteWFopiynaPENTYxm1BiZcGEZy40Dit2ePO-Li7vobgoauqNagMMfoZ3jk-q_POy9Pb8f4YY_9Bs-lvtDBCUuUYwhMHYV7KiYhlm0TMoxGnRrd7_KGuZK-KgP3KcJdaQrTR7Nj8NM2qpvDuj3OMovl6neRp0twHztXJLjShsWYaool-DEhXLQOlR99E78GSDqF7mt2SHIoCSXjqybHLtiHMMDoslN7hOpSHV1sAz9s9PbzjmtmRNoHqlkRENmMuMPM7RIpGpbkRRCaYlwV0Qis9zEbW5FaBQ26raNWCE1D60pCmnbieErMFM-lsUaEJSRMiG32kRaiJxrqaXKEldDxsQ21AGEjYzSvC4r7tgtHlIPL2KZVnJNUa6pl2sqAtgZv_NUFdX4s_dmI_q00Y8UkRBH3wznEcBqtQrjobhgCr2sKAA1sT7jDq6k9mRLObj3pbU9_ozCAHablfz85O8zXP_X_2zAHHNK5mNiNmFm9PJabKFnM8paMHty2ru6bsF0hwn3lJ2WPyVoeUXGZ--q-wFz9vSs
linkProvider Scholars Portal
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV3NTtwwEB7BciiXqhUUQmnrQzm1Font2DESqqAFLQUW1C4SN-PEtkCqAu0uQrxUn7G2k-xqi-DG2Y5jzYw983n-AD66QmhNrcGlcBR7jW-wNJpgY7ikzBFSmQAUjwe8f8a-n-fnc_C3y4UJYZXdnRgvanNdhTfyTW_6Uq-MJS2-3PzGoWtU8K52LTQasTi093ceso22D755_m4Qsr83_NrHbVcBXOVCjnFGTGki0NdMcpE6Ji0TmnsoyHJWOmqKlDqWGeEHdepyYrmmmTPWcpdKQ_2687DAKE9JDxZ29wanP6avOjkVLMaV-JtA4tDWpcvUKfjmyKOnkNFGPIIPpfYwm9WGD0zch5Ga_7lroxbcfwUvW_MV7TTy9hrmbL0EuyFYBLfB8ON7FF8ZvQSjYdt_Al3V6CS0A0c7odzHaAtp9LOKqVqocU4sw9mzUPEN9Orr2q4C8jQSJqNOm1wzVlHNNRelDFVqTOEynUDW0UhVbeHy0D_jl4oApuCqoavydFWRrool8GnyzU1TtuPJ2esd6VV7hEdqKnAJrDRcmCxFGRHejssTEDP8mUwIRbtnR-qry1i8OyLcPEvgc8fJ6S8f3-Ha0zv8AC_6w-MjdXQwOHwLiyRIWAy5WYfe-M-tfecNp3H5vpVWBBfPfUD-AWctJfA
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV1LS8QwEB50F8SL-La6ag7eNLht0qT1tj4WXZ-ggreQNg0KUsWtB_-9SZquri_wnDQN82BmMjPfAGzphEtJCoUzrgk2Fl_hVMkIK8VSQnUU5coGiucX7PiWDu7iu09d_K7avUlJ1j0NFqWprHafla5VPGG7QxOG2NawyITCFrMO00loJ8xoTAvavd7getDIVGzx0IjPNNadw4RTV_lhdDXFdvBK00vz48Hj9uqbE_q9lvJLQtXZqf4szHgHE_VqiZiDiaKch6lzn0JfgH1b2YF95Xr1htyToBE3dOOHRaCHEl3a2d2oZ7E5hntIouvc9VWhOpOwCLf9o5uDY-wHKeA85mmFw0hlyr1tSJoy3tU0LSiXzES_NKaZJirpEk1Dxc2i7Oo4KpgkoVZFwXQ3VWQJWuVTWawAMuTiKiRaqlhSmhPJJONZaiFlVKJDGUDYkEvkHmXcDrt4FC7aSJioSSwMiYUjsaABbI--ea4xNv7c3Wm4ILy-DYUJjIhx1cw9AliuGTI6itCIG6crDoCPsWq0wSJsj6-UD_cOaduFo3EYwE7D1I9f_n7D1f9t34Spq8O-ODu5OF2D6cjKniuX6UCrenkt1o3TU2UbXq7fAT5F9LI
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=High-Intensity+Interval+Training+in+Older+Adults%3A+a+Scoping+Review&rft.jtitle=Sports+medicine+-+open&rft.au=Marriott%2C+Catherine+F.+S.&rft.au=Petrella%2C+Andrea+F.+M.&rft.au=Marriott%2C+Emily+C.+S.&rft.au=Boa+Sorte+Silva%2C+Narlon+C.&rft.date=2021-12-01&rft.issn=2199-1170&rft.eissn=2198-9761&rft.volume=7&rft.issue=1&rft_id=info:doi/10.1186%2Fs40798-021-00344-4&rft.externalDBID=n%2Fa&rft.externalDocID=10_1186_s40798_021_00344_4
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2199-1170&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2199-1170&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2199-1170&client=summon