绿激光汽化术治疗膀胱肿瘤522例临床观察

目的 探讨经尿道膀胱肿瘤绿激光汽化术（PVBT）治疗膀胱尿路上皮癌的疗效及安全性.方法 2010年1月—2015年5月期间,共收治膀胱尿路上皮癌患者522例,其中非肌层浸润性膀胱癌（NMIBC）405例,肌层浸润性膀胱癌（MIBC）117例.均采用PVBT治疗,术后膀胱灌注表柔比星,其中MIBC患者联合术后静脉化疗（吉西他滨＋顺铂）.结果 NMIBC组住院时间（7.32±1.28）d,手术时间（27.08±5.36）min,留置尿管时间（2.42±0.34）d,术后随访12～60个月,复发38例（9.4％）,其中3例行根治性膀胱切除术,余35例再次行PVBT;405例患者全部存活.MIBC组住...

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Bibliographic Details
Published in天津医药 Vol. 45; no. 9; pp. 976 - 979
Main Author 张志华 陈雅童 李昭夷 张廷继 冯起庆 李健
Format Journal Article
LanguageChinese
Published 天津市人民医院泌尿外科 300121 2017
Subjects
复发
激光治疗
绿激光汽化术
肌层浸润性膀胱癌
膀胱肿瘤
随访
非肌层浸润性膀胱癌
随访
膀胱肿瘤
激光治疗
laser therapy
复发
follow up
非肌层浸润性膀胱癌
recurrence
肌层浸润性膀胱癌
greenlight vaporization
muscle-invasive bladder cancer
绿激光汽化术
urinary bladder neoplasms
non muscle-invasive bladder cancer
Online AccessGet full text
ISSN0253-9896
DOI10.11958/20170420

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Summary:目的 探讨经尿道膀胱肿瘤绿激光汽化术（PVBT）治疗膀胱尿路上皮癌的疗效及安全性.方法 2010年1月—2015年5月期间,共收治膀胱尿路上皮癌患者522例,其中非肌层浸润性膀胱癌（NMIBC）405例,肌层浸润性膀胱癌（MIBC）117例.均采用PVBT治疗,术后膀胱灌注表柔比星,其中MIBC患者联合术后静脉化疗（吉西他滨＋顺铂）.结果 NMIBC组住院时间（7.32±1.28）d,手术时间（27.08±5.36）min,留置尿管时间（2.42±0.34）d,术后随访12～60个月,复发38例（9.4％）,其中3例行根治性膀胱切除术,余35例再次行PVBT;405例患者全部存活.MIBC组住院时间（26.18±1.92）d,手术时间（38.32±6.54）min,留置尿管时间（2.72±0.85）d,术后随访12～60个月,复发19例（16.2％）,4例患者行根治性膀胱切除术,余15例再次行PVBT;复发者中有6例死于膀胱癌远处转移（2例肺转移,4例骨转移）,余111例存活.结论 PVBT是安全、有效的手术方式,尤其适用于NMIBC及不能或不愿行根治性膀胱切除术的MIBC患者.
Bibliography:ZHANG Zhi-hua, CHEN Ya-tong, LI Zhao-yi, ZHANG Ting-ji, FENG Qi-qing, LI Jian（ Department of Urology, Tianjin Union Medicine Center, Tianjin 300121, China）
urinary bladder neoplasms;recurrence;follow up;non muscle-invasive bladder cancer;muscle-invasive bladder cancer;laser therapy;greenlight vaporization
Objective To investigate the safety and efficacy of photoselective green laser vaporization of bladder tumor （PVBT）. Methods A total of 522 patients with bladder tumor were enrolled in present study from January 2010 to May 2015, including 405 cases of non muscle-invasive bladder cancer （NMIBC） and 117 cases of muscle-invasive bladder cancer （MIBC）. All of patients were treated with PVBT and intravesical instillation of epirubicin. Patients with MIBC received intravenous chemotherapy （kisi-hama and cisplatin）. Results The hospitalization time was （7.32±1.28） days, the operation time was （27.08±5.36） min, and the indwelling urinary catheter was （2.42±0.34） days for patients in NMIBC group. During the follow-up
ISSN:0253-9896
DOI:10.11958/20170420