Calcium-sensing receptors signal constitutive macropinocytosis and facilitate the uptake of NOD2 ligands in macrophages - Canton, Johnathan; Schlam, Daniel; Breuer, Christian; Gütschow, Michael; Glogauer, Michael; Grinstein, Sergio (Nature communications, 2016)
Keywords: 1-Phosphatidylinositol 3-kinase; 631/250/2504/342; 631/80/313/1461; 631/80/86/1999; Actin; Animals; Antigen presentation; Antigens; Calcium; Calcium (extracellular); Calcium - metabolism; Calcium signalling; Calcium-sensing receptors; Cdc42 protein; Cytoskeleton - metabolism; Cytosol - metabolism; Dendritic cells; Extracellular Space - metabolism; G protein-coupled receptors; Growth factors; GTP-Binding Protein alpha Subunits - metabolism; HEK293 Cells; Humanities and Social Sciences; Humans; Intracellular Space - metabolism; Kinases; Ligands; Macrophages; Macrophages - metabolism; Mice; Monocytes - cytology; multidisciplinary; NOD2 protein; Nod2 Signaling Adaptor Protein - metabolism; Pattern recognition; Phosphatidylinositol 3-Kinases - metabolism; Phospholipase; Phospholipase C; Phospholipase C gamma - metabolism; Pinocytosis; Proteins; Receptors; Receptors, Calcium-Sensing - metabolism; Science; Science (multidisciplinary); Signal Transduction