The increasing complexity of arbovirus serology: An in-depth systematic review on cross-reactivity

• Published in: PLoS neglected tropical diseases Vol. 17; no. 9; p. e0011651
• Main Authors: Kasbergen, Louella M. R., Nieuwenhuijse, David F., de Bruin, Erwin, Sikkema, Reina S., Koopmans, Marion P. G.
• Format: Journal Article
• Language: English
• Published: San Francisco Public Library of Science 22.09.2023; Public Library of Science (PLoS)
• Subjects: Antibodies; Arbovirus diseases; Arthropods; Assaying; Biology and Life Sciences; Chikungunya virus; Cross reactions (Immunology); Cross-reactivity; Datasets; Dengue fever; Diagnosis; Epidemics; Exposure; Immunization; Immunological research; Infections; Medicine and Health Sciences; Serodiagnosis; Serology; Standardization; Systematic review; Vaccination; Vaccines; West Nile virus; Zika virus; Netherlands; France; Europe

Diagnosis of arbovirus infection or exposure by antibody testing is becoming increasingly difficult due to global expansion of arboviruses, which induce antibodies that may (cross-)react in serological assays. We provide a systematic review of the current knowledge and knowledge gaps in differential...