Exposure to ACE inhibitors prior to the onset of scleroderma renal crisis—Results from the International Scleroderma Renal Crisis Survey

• Published in: Seminars in arthritis and rheumatism Vol. 43; no. 5; pp. 666 - 672
• Main Authors: Hudson, Marie, Baron, Murray, Tatibouet, Solène, Furst, Daniel E., Khanna, Dinesh
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.04.2014
• Subjects: ACE inhibitors; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors - adverse effects; Angiotensin-Converting Enzyme Inhibitors - therapeutic use; Cohort Studies; Female; Follow-Up Studies; Humans; Kidney Diseases - etiology; Male; Middle Aged; Prospective Studies; Rheumatology; Scleroderma; Scleroderma renal crisis; Scleroderma, Systemic - complications; Severity of Illness Index; Scleroderma; Scleroderma renal crisis; ACE inhibitors

To determine whether exposure to angiotensin-converting enzyme (ACE) inhibitors prior to the onset of scleroderma renal crisis (SRC) leads to worse outcomes of SRC. Prospective cohort study of incident SRC subjects. The exposure of interest was ACE inhibitors prior to the onset of SRC. The outcomes...