Live-Cell FRET Imaging Reveals a Role of Extracellular Signal-Regulated Kinase Activity Dynamics in Thymocyte Motility

Extracellular signal-regulated kinase (ERK) plays critical roles in T cell development in the thymus. Nevertheless, the dynamics of ERK activity and the role of ERK in regulating thymocyte motility remain largely unknown due to technical limitations. To visualize ERK activity in thymocytes, we here...

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Bibliographic Details
Published iniScience Vol. 10; pp. 98 - 113
Main Authors Konishi, Yoshinobu, Terai, Kenta, Furuta, Yasuhide, Kiyonari, Hiroshi, Abe, Takaya, Ueda, Yoshihiro, Kinashi, Tatsuo, Hamazaki, Yoko, Takaori-Kondo, Akifumi, Matsuda, Michiyuki
Format Journal Article
LanguageEnglish
Published United States Elsevier 21.12.2018
Subjects
Molecular Biology
Biological Sciences
Components of the Immune System
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ISSN2589-0042
2589-0042
DOI10.1016/j.isci.2018.11.025

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