A meta-analytic study of changes in brain activation in depression

• Published in: Human brain mapping Vol. 29; no. 6; pp. 683 - 695
• Main Authors: Fitzgerald, Paul B., Laird, Angela R., Maller, Jerome, Daskalakis, Zafiris J.
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.06.2008; Wiley-Liss
• Subjects: Biological and medical sciences; Brain - diagnostic imaging; Brain - physiopathology; depression; Depressive Disorder, Major - diagnostic imaging; Depressive Disorder, Major - physiopathology; Electrodiagnosis. Electric activity recording; fMRI; Humans; Investigative techniques, diagnostic techniques (general aspects); Magnetic Resonance Imaging; Medical sciences; meta-analysis; Nervous system; Positron-Emission Tomography; Radiodiagnosis. Nmr imagery. Nmr spectrometry; Tomography, Emission-Computed, Single-Photon; fMRI; Nervous system diseases; Radiodiagnosis; Central nervous system; meta-analysis; depression; Nuclear magnetic resonance imaging; Encephalon

Objective: A large number of studies with considerably variable methods have been performed to investigate brain regions involved in the pathophysiology of major depressive disorder. The aim of this study was to use a quantitative meta‐analytic technique to synthesise the results of much of this res...