Impact of time-of-day on brain morphometric measures derived from T1-weighted magnetic resonance imaging

• Published in: NeuroImage (Orlando, Fla.) Vol. 133; pp. 41 - 52
• Main Authors: Trefler, Aaron, Sadeghi, Neda, Thomas, Adam G., Pierpaoli, Carlo, Baker, Chris I., Thomas, Cibu
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.06.2016; Elsevier Limited
• Subjects: Alzheimer's disease; Brain; Brain - anatomy & histology; Diffusion Magnetic Resonance Imaging - methods; Female; Humans; Image Interpretation, Computer-Assisted - methods; Imaging, Three-Dimensional - methods; Male; Medical imaging; NMR; Nuclear magnetic resonance; Reference Values; Reproducibility of Results; Rodents; Sensitivity and Specificity; Software packages; Studies; Ultradian Rhythm - physiology; Young Adult

Measures of brain morphometry derived from T1-weighted (T1W) magnetic resonance imaging (MRI) are widely used to elucidate the relation between brain structure and function. However, the computation of T1W morphometric measures can be confounded by subject-related factors such as head motion and lev...