Priming of neutrophil oxidative burst in diabetes requires preassembly of the NADPH oxidase

Hyperglycemia associated with diabetes mellitus results in the priming of neutrophils leading to oxidative stress that is, in part, responsible for diabetic complications. p47phox, a NADPH oxidase cytosolic subunit, is a key protein in the assembly of the NADPH oxidase leading to superoxide generati...

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Published inJournal of leukocyte biology Vol. 84; no. 1; pp. 292 - 301
Main Authors Omori, Kazuhiro, Ohira, Taisuke, Uchida, Yushi, Ayilavarapu, Srinivas, Batista, Eraldo L., Yagi, Motohiko, Iwata, Tomoyuki, Liu, Hongsheng, Hasturk, Hatice, Kantarci, Alpdogan, Van Dyke, Thomas E.
Format Journal Article
LanguageEnglish
Published United States Society for Leukocyte Biology 01.07.2008
The Society for Leukocyte Biology
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Abstract Hyperglycemia associated with diabetes mellitus results in the priming of neutrophils leading to oxidative stress that is, in part, responsible for diabetic complications. p47phox, a NADPH oxidase cytosolic subunit, is a key protein in the assembly of the NADPH oxidase leading to superoxide generation. Little is known about the priming mechanism of oxidative pathways in neutrophils of people with diabetes. In this study, the kinetics of p47phox activation was investigated by comparing neutrophils from diabetic and healthy subjects, and the mechanism of hyperglycemia‐induced changes was studied by using neutrophil‐like HL‐60 cells as a model. In resting neutrophils from diabetic subjects, p47phox prematurely translocates to the cell membrane and preassembles with p22phox, a NADPH oxidase membrane subunit. This premature p47phox translocation and preassembly with p22phox were also observed in HL‐60 cells cultured with high glucose (HG; 25 mM) and with the specific ligand for the receptor for advanced glycation end products (RAGE), S100B. Phosphorylation of ERK1/2, but not p38 MAPK, was the primary signaling pathway, as evidenced by PD98059 suppressing the translocation of p47phox in HL‐60 cells incubated with HG and S100B. HL‐60 cells cultured in HG and S100B exhibited a 1.8‐fold increase in fMLP‐induced superoxide generation compared with those cultured in normal glucose (5.5 mM). These data suggest that HG and increased AGE prime neutrophils and increase oxidative stress inducing the translocation of p47phox to the cell membrane and preassembly with p22phox by stimulating a RAGE‐ERK1/2 pathway.
AbstractList Hyperglycemia associated with diabetes mellitus results in the priming of neutrophils leading to oxidative stress that is, in part, responsible for diabetic complications. p47 super(phox), a NADPH oxidase cytosolic subunit, is a key protein in the assembly of the NADPH oxidase leading to superoxide generation. Little is known about the priming mechanism of oxidative pathways in neutrophils of people with diabetes. In this study, the kinetics of p47 super(phox) activation was investigated by comparing neutrophils from diabetic and healthy subjects, and the mechanism of hyperglycemia-induced changes was studied by using neutrophil-like HL-60 cells as a model. In resting neutrophils from diabetic subjects, p47 super(phox) prematurely translocates to the cell membrane and preassembles with p22 super(phox), a NADPH oxidase membrane subunit. This premature p41 super(phox) translocation and preassembly with p22 super(phox) were also observed in HL-60 cells cultured with high glucose (HG; 25 mM) and with the specific ligand for the receptor for advanced glycation end products (RAGE), S100B. Phosphorylation of ERK1/2, but not p38 MAPK, was the primary signaling pathway, as evidenced by PD98059 suppressing the translocation of p47 super(phox) in HL-60 cells incubated with HG and S100B. HL-60 cells cultured in HG and S100B exhibited a 1.8-fold increase in fMLP-induced superoxide generation compared with those cultured in normal glucose (5.5 mM). These data suggest that HG and increased AGE prime neutrophils and increase oxidative stress inducing the translocation of p47 super(phox) to the cell membrane and preassembly with p22 super(phox) by stimulating a RAGE-ERK1/2 pathway.
Hyperglycemia associated with diabetes mellitus results in the priming of neutrophils leading to oxidative stress that is, in part, responsible for diabetic complications. p47 super(phox), a NADPH oxidase cytosolic subunit, is a key protein in the assembly of the NADPH oxidase leading to superoxide generation. Little is known about the priming mechanism of oxidative pathways in neutrophils of people with diabetes. In this study, the kinetics of p47 super(phox) activation was investigated by comparing neutrophils from diabetic and healthy subjects, and the mechanism of hyperglycemia-induced changes was studied by using neutrophil-like HL-60 cells as a model. In resting neutrophils from diabetic subjects, p47 super(phox) prematurely translocates to the cell membrane and preassembles with p22 super(phox), a NADPH oxidase membrane subunit. This premature p47 super(phox) translocation and preassembly with p22 super(phox) were also observed in HL-60 cells cultured with high glucose (HG; 25 mM) and with the specific ligand for the receptor for advanced glycation end products (RAGE), S100B. Phosphorylation of ERK1/2, but not p38 MAPK, was the primary signaling pathway, as evidenced by PD98059 suppressing the translocation of p47 super(phox) in HL-60 cells incubated with HG and S100B. HL-60 cells cultured in HG and S100B exhibited a 1.8-fold increase in fMLP-induced superoxide generation compared with those cultured in normal glucose (5.5 mM). These data suggest that HG and increased AGE prime neutrophils and increase oxidative stress inducing the translocation of p47 super(phox) to the cell membrane and preassembly with p22 super(phox) by stimulating a RAGE-ERK1/2 pathway.
Hyperglycemia associated with diabetes mellitus results in the priming of neutrophils leading to oxidative stress that is, in part, responsible for diabetic complications. p47phox, a NADPH oxidase cytosolic subunit, is a key protein in the assembly of the NADPH oxidase leading to superoxide generation. Little is known about the priming mechanism of oxidative pathways in neutrophils of people with diabetes. In this study, the kinetics of p47phox activation was investigated by comparing neutrophils from diabetic and healthy subjects, and the mechanism of hyperglycemia-induced changes was studied by using neutrophil-like HL-60 cells as a model. In resting neutrophils from diabetic subjects, p47phox prematurely translocates to the cell membrane and preassembles with p22phox, a NADPH oxidase membrane subunit. This premature p47phox translocation and preassembly with p22phox were also observed in HL-60 cells cultured with high glucose (HG; 25 mM) and with the specific ligand for the receptor for advanced glycation end products (RAGE), S100B. Phosphorylation of ERK1/2, but not p38 MAPK, was the primary signaling pathway, as evidenced by PD98059 suppressing the translocation of p47phox in HL-60 cells incubated with HG and S100B. HL-60 cells cultured in HG and S100B exhibited a 1.8-fold increase in fMLP-induced superoxide generation compared with those cultured in normal glucose (5.5 mM). These data suggest that HG and increased AGE prime neutrophils and increase oxidative stress inducing the translocation of p47phox to the cell membrane and preassembly with p22phox by stimulating a RAGE-ERK1/2 pathway.
Hyperglycemia associated with diabetes mellitus results in the priming of neutrophils leading to oxidative stress that is, in part, responsible for diabetic complications. p47 phox , a NADPH oxidase cytosolic subunit, is a key protein in the assembly of the NADPH oxidase leading to superoxide generation. Little is known about the priming mechanism of oxidative pathways in neutrophils of people with diabetes. In this study, the kinetics of p47 phox activation was investigated by comparing neutrophils from diabetic and healthy subjects, and the mechanism of hyperglycemia-induced changes was studied by using neutrophil-like HL-60 cells as a model. In resting neutrophils from diabetic subjects, p47 phox prematurely translocates to the cell membrane and preassembles with p22 phox , a NADPH oxidase membrane subunit. This premature p47 phox translocation and preassembly with p22 phox were also observed in HL-60 cells cultured with high glucose (HG; 25 mM) and with the specific ligand for the receptor for advanced glycation end products (RAGE), S100B. Phosphorylation of ERK1/2, but not p38 MAPK, was the primary signaling pathway, as evidenced by PD98059 suppressing the translocation of p47 phox in HL-60 cells incubated with HG and S100B. HL-60 cells cultured in HG and S100B exhibited a 1.8-fold increase in fMLP-induced superoxide generation compared with those cultured in normal glucose (5.5 mM). These data suggest that HG and increased AGE prime neutrophils and increase oxidative stress inducing the translocation of p47 phox to the cell membrane and preassembly with p22 phox by stimulating a RAGE-ERK1/2 pathway.
Author Taisuke Ohira
Srinivas Ayilavarapu
Kazuhiro Omori
Yushi Uchida
Eraldo L. Batista, Jr
Thomas E. Van Dyke
Tomoyuki Iwata
Hatice Hasturk
Motohiko Yagi
Alpdogan Kantarci
Hongsheng Liu
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  surname: Van Dyke
  fullname: Van Dyke, Thomas E.
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Cites_doi 10.1172/JCI27544
10.1074/jbc.M311688200
10.1016/S0092-8674(03)00314-3
10.1189/jlb.1004583
10.1016/S0021-9258(19)88641-6
10.1016/S0021-9258(18)42138-2
10.1002/dmrr.196
10.1016/S0021-9258(17)43161-9
10.1189/jlb.1204697
10.1016/S1043-4682(05)80005-4
10.1074/jbc.274.47.33644
10.2337/diacare.26.2007.S5
10.1902/annals.2001.6.1.125
10.1128/iai.61.8.3137-3142.1993
10.2174/138955706776073501
10.1055/s-2006-955084
10.1182/blood.V93.5.1464
10.1038/414782a
10.4049/jimmunol.177.10.7250
10.1002/dmrr.233
10.1007/s00418-004-0672-2
10.1016/S0014-5793(03)00845-7
10.1016/S0092-8674(00)80801-6
10.1074/jbc.M302828200
10.1074/jbc.274.44.31740
10.1016/S1262-3636(07)70243-4
10.4049/jimmunol.173.3.2091
10.1042/BJ20051810
10.1002/jlb.64.4.537
10.1172/JCI10842
10.1074/jbc.M506594200
10.1074/jbc.272.47.29502
10.1002/dmrr.625
10.1084/jem.149.4.969
10.1172/JCI109007
10.2337/diacare.24.1.104
10.1016/S0021-9258(17)31418-7
10.1084/jem.182.3.751
10.2337/dc05-2096
10.1189/jlb.0404216
10.1007/s001250100001
10.1016/S0002-9343(00)00481-2
10.1016/j.cellsig.2004.06.008
10.1016/S0021-9258(18)42137-0
10.1002/jcb.20356
10.1161/01.ATV.14.10.1521
10.1042/BJ20041835
10.1172/JCI200114002
10.1056/NEJM199910073411506
10.1016/S0014-4827(03)00071-5
10.1016/0304-3835(80)90062-2
10.1002/jcp.10119
10.1172/JCI949
10.1189/jlb.71.3.433
10.1161/01.RES.0000137876.28454.64
10.1016/0167-5699(95)80178-2
10.1182/blood.V64.5.959.959
10.1902/jop.2003.74.1.66
10.1902/annals.2001.6.1.91
10.1016/S0021-9258(18)63792-5
10.1074/jbc.M511425200
10.1189/jlb.0406262
10.1056/NEJM198805193182007
10.1182/blood-2001-11-0122
10.1146/annurev.immunol.23.021704.115653
10.4049/jimmunol.178.8.5253
10.1073/pnas.75.5.2458
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Current address: Center for Research in Molecular and Functional Biology, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, RS, Brazil.
Current address: Department of Periodontal Medicine, Division of Frontier Medical Science, Hiroshima University Graduate School of Biomedical Science, Hiroshima, Japan.
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References 2004; 122
1979; 149
1984; 64
2002; 192
1993; 61
2006; 32
1997; 272
1978; 75
2006; 38
2001; 44
2001; 108
2003; 278
2003; 113
2005; 23
2006; 177
2003; 550
2004; 76
2007; 178
1994; 269
2005; 386
2006; 22
2004; 173
1989; 264
2002; 100
1978; 61
2006; 29
1999; 97
2001; 17
2006; 281
1999; 93
2005; 77
2005; 78
2003; 286
2001; 414
1995; 16
1992; 267
1999; 341
2006; 6
2006; 116
2001; 24
1998; 64
2003; 74
2006; 398
1995; 6
2005; 280
2004; 95
2004; 279
2001; 6
2000; 106
1984; 259
1980; 10
2000; 109
1999; 274
1994; 14
2003; 26
2007; 81
2002; 71
2005; 94
1988; 318
2005; 17
1998; 101
1995; 182
12593599 - J Periodontol. 2003 Jan;74(1):66-75
276884 - Proc Natl Acad Sci U S A. 1978 May;75(5):2458-62
10531386 - J Biol Chem. 1999 Oct 29;274(44):31740-9
15689384 - J Leukoc Biol. 2005 May;77(5):598-625
11742409 - Nature. 2001 Dec 13;414(6865):782-7
9766635 - J Leukoc Biol. 1998 Oct;64(4):537-45
15494208 - Cell Signal. 2005 Feb;17(2):167-75
12115731 - J Cell Physiol. 2002 Jul;192(1):1-15
16778989 - J Clin Invest. 2006 Jul;116(7):2033-43
26695 - J Clin Invest. 1978 Apr;61(4):1081-7
11194213 - Diabetes Care. 2001 Jan;24(1):104-10
10953022 - J Clin Invest. 2000 Aug;106(4):473-81
16115878 - J Biol Chem. 2005 Nov 4;280(44):37021-32
17082643 - J Immunol. 2006 Nov 15;177(10):7250-6
14676217 - J Biol Chem. 2004 Feb 20;279(8):6643-9
10936476 - Am J Med. 2000 Jul;109(1):33-44
17095613 - J Leukoc Biol. 2007 Feb;81(2):520-7
10559253 - J Biol Chem. 1999 Nov 19;274(47):33644-53
10399917 - Cell. 1999 Jun 25;97(7):889-901
12837757 - J Biol Chem. 2003 Sep 12;278(37):34834-44
15588255 - Biochem J. 2005 Mar 15;386(Pt 3):401-16
11887455 - Ann Periodontol. 2001 Dec;6(1):125-37
16732039 - Diabetes Care. 2006 Jun;29(6):1420-32
219131 - J Exp Med. 1979 Apr 1;149(4):969-74
12732142 - Cell. 2003 May 2;113(3):343-55
15240752 - J Leukoc Biol. 2004 Oct;76(4):760-81
16626305 - Biochem J. 2006 Aug 15;398(1):73-82
1378843 - J Biol Chem. 1992 Jul 25;267(21):14998-5004
10511612 - N Engl J Med. 1999 Oct 7;341(15):1127-33
12935894 - FEBS Lett. 2003 Aug 28;550(1-3):101-6
11424232 - Diabetes Metab Res Rev. 2001 May-Jun;17(3):189-212
12749849 - Exp Cell Res. 2003 Jun 10;286(2):199-208
8748142 - Semin Cell Biol. 1995 Dec;6(6):345-56
16523183 - Diabetes Metab. 2006 Feb;32(1):15-29
15578578 - J Cell Biochem. 2005 Mar 1;94(4):774-93
16081595 - J Leukoc Biol. 2005 Oct;78(4):862-70
16551628 - J Biol Chem. 2006 May 12;281(19):13685-93
11757079 - Diabetes Metab Res Rev. 2001 Nov-Dec;17(6):436-43
6323439 - J Biol Chem. 1984 Mar 25;259(6):3771-6
7650482 - J Exp Med. 1995 Sep 1;182(3):751-8
17111300 - Horm Metab Res. 2006 Nov;38(11):732-9
11867681 - J Leukoc Biol. 2002 Mar;71(3):433-44
11887477 - Ann Periodontol. 2001 Dec;6(1):91-8
1328185 - J Biol Chem. 1992 Oct 5;267(28):19901-6
1321822 - J Biol Chem. 1992 Jul 25;267(21):14987-97
17404309 - J Immunol. 2007 Apr 15;178(8):5253-61
11581294 - J Clin Invest. 2001 Oct;108(7):949-55
8335344 - Infect Immun. 1993 Aug;61(8):3137-42
7918300 - Arterioscler Thromb. 1994 Oct;14(10):1521-8
2549043 - J Biol Chem. 1989 Sep 5;264(25):14935-9
7662095 - Immunol Today. 1995 Jun;16(6):264-8
6939481 - Cancer Lett. 1980 Jul;10(1):33-8
11719828 - Diabetologia. 2001 Nov;44(11):1973-88
15265945 - J Immunol. 2004 Aug 1;173(3):2091-8
15297385 - Circ Res. 2004 Aug 6;95(3):233-8
6386073 - Blood. 1984 Nov;64(5):959-66
12502614 - Diabetes Care. 2003 Jan;26 Suppl 1:S5-20
7929117 - J Biol Chem. 1994 Oct 7;269(40):24519-22
15771570 - Annu Rev Immunol. 2005;23:197-223
3283558 - N Engl J Med. 1988 May 19;318(20):1315-21
12239175 - Blood. 2002 Oct 1;100(7):2607-16
9368011 - J Biol Chem. 1997 Nov 21;272(47):29502-10
15365846 - Histochem Cell Biol. 2004 Oct;122(4):293-304
10029572 - Blood. 1999 Mar 1;93(5):1464-76
16515470 - Mini Rev Med Chem. 2006 Mar;6(3):313-8
16506271 - Diabetes Metab Res Rev. 2006 Jul-Aug;22(4):257-73
9435318 - J Clin Invest. 1998 Jan 15;101(2):455-63
Renard (2023032712571963600_) 2006; 32
Groemping (2023032712571963600_) 2003; 113
Collison (2023032712571963600_) 2002; 71
Ritz (2023032712571963600_) 1999; 341
Kurihara (2023032712571963600_) 1993; 61
Guichard (2023032712571963600_) 2005; 280
Expert Committee on the Diagnosis and Classification of Diabetes Mellitus (2023032712571963600_) 2003; 26
Swain (2023032712571963600_) 1997; 272
Schmidt (2023032712571963600_) 1994; 14
Chanock (2023032712571963600_) 1994; 269
Downey (2023032712571963600_) 1995; 6
Wautier (2023032712571963600_) 2004; 95
Quinn (2023032712571963600_) 2004; 76
Collins (2023032712571963600_) 1979; 149
Hofmann (2023032712571963600_) 1999; 97
Bellin (2023032712571963600_) 2006; 38
Takeda (2023032712571963600_) 2003; 286
Martindale (2023032712571963600_) 2002; 192
Zimmet (2023032712571963600_) 2001; 414
Schmidt (2023032712571963600_) 2001; 108
Jackson (2023032712571963600_) 1995; 182
Omori (2023032712571963600_) 2004; 279
Ago (2023032712571963600_) 1999; 274
Klebanoff (2023032712571963600_) 2005; 77
Kannan (2023032712571963600_) 2007; 178
Reddy (2023032712571963600_) 2006; 281
Babior (2023032712571963600_) 2000; 109
Groemping (2023032712571963600_) 2005; 386
Dang (2023032712571963600_) 2006; 116
Shurtz-Swirski (2023032712571963600_) 2001; 24
Ding (2023032712571963600_) 2007; 81
Collins (2023032712571963600_) 1978; 75
Yamagishi (2023032712571963600_) 2006; 6
Batista (2023032712571963600_) 2005; 94
Shanmugam (2023032712571963600_) 2003; 278
Brownlee (2023032712571963600_) 1988; 318
Cohen (2023032712571963600_) 1978; 61
Cowburn (2023032712571963600_) 2002; 100
Gyurko (2023032712571963600_) 2006; 177
Iacopino (2023032712571963600_) 2001; 6
Shao (2023032712571963600_) 2003; 550
DeLeo (2023032712571963600_) 1998; 101
Kahn (2023032712571963600_) 2000; 106
Kantarci (2023032712571963600_) 2003; 74
Neeper (2023032712571963600_) 1992; 267
Huebschmann (2023032712571963600_) 2006; 29
Kislinger (2023032712571963600_) 1999; 274
Babior (2023032712571963600_) 1999; 93
Karima (2023032712571963600_) 2005; 78
Segal (2023032712571963600_) 2005; 23
Robinson (2023032712571963600_) 2004; 122
McLeish (2023032712571963600_) 1998; 64
Heyworth (2023032712571963600_) 1989; 264
Vlassara (2023032712571963600_) 2001; 17
Fujita (2023032712571963600_) 2005; 17
Cameron (2023032712571963600_) 2001; 44
Park (2023032712571963600_) 1992; 267
Babior (2023032712571963600_) 1984; 64
Pop-Busui (2023032712571963600_) 2006; 22
Soskolne (2023032712571963600_) 2001; 6
Siow (2023032712571963600_) 2006; 398
Rosen (2023032712571963600_) 2001; 17
Papac (2023032712571963600_) 1980; 10
Ohira (2023032712571963600_) 2004; 173
Schmidt (2023032712571963600_) 1992; 267
Newburger (2023032712571963600_) 1984; 259
Hallett (2023032712571963600_) 1995; 16
References_xml – volume: 259
  start-page: 3771
  year: 1984
  end-page: 3776
  article-title: Development of the superoxide‐generating system during differentiation of the HL‐60 human promyelocytic leukemia cell line
  publication-title: J. Biol. Chem.
– volume: 109
  start-page: 33
  year: 2000
  end-page: 44
  article-title: Phagocytes and oxidative stress
  publication-title: Am. J. Med.
– volume: 93
  start-page: 1464
  year: 1999
  end-page: 1476
  article-title: NADPH oxidase: an update
  publication-title: Blood
– volume: 14
  start-page: 1521
  year: 1994
  end-page: 1528
  article-title: Cellular receptors for advanced glycation end products. Implications for induction of oxidant stress and cellular dysfunction in the pathogenesis of vascular lesions
  publication-title: Arterioscler. Thromb.
– volume: 192
  start-page: 1
  year: 2002
  end-page: 15
  article-title: Cellular response to oxidative stress: signaling for suicide and survival
  publication-title: J. Cell. Physiol.
– volume: 61
  start-page: 1081
  year: 1978
  end-page: 1087
  article-title: Superoxide generation by digitonin‐stimulated guinea pig granulocytes. A basis for a continuous assay for monitoring superoxide production and for the study of the activation of the generating system
  publication-title: J. Clin. Invest.
– volume: 10
  start-page: 33
  year: 1980
  end-page: 38
  article-title: Differentiation of human promyelocytic leukemia cells in vitro by 6‐thio‐guanine
  publication-title: Cancer Lett.
– volume: 76
  start-page: 760
  year: 2004
  end-page: 781
  article-title: Structure and regulation of the neutrophil respiratory burst oxidase: comparison with nonphagocyte oxidases
  publication-title: J. Leukoc. Biol.
– volume: 108
  start-page: 949
  year: 2001
  end-page: 955
  article-title: The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses
  publication-title: J. Clin. Invest.
– volume: 279
  start-page: 6643
  year: 2004
  end-page: 6649
  article-title: High glucose enhances interleukin‐6‐induced vascular endothelial growth factor 165 expression via activation of gp130‐mediated p44/42 MAPK‐CCAAT/enhancer binding protein signaling in gingival fibroblasts
  publication-title: J. Biol. Chem.
– volume: 61
  start-page: 3137
  year: 1993
  end-page: 3142
  article-title: Calcium‐dependent protein kinase C activity of neutrophils in localized juvenile periodontitis
  publication-title: Infect. Immun.
– volume: 272
  start-page: 29502
  year: 1997
  end-page: 29510
  article-title: Analysis of activation‐induced conformational changes in p47phox using tryptophan fluorescence spectroscopy
  publication-title: J. Biol. Chem.
– volume: 77
  start-page: 598
  year: 2005
  end-page: 625
  article-title: Myeloperoxidase: friend and foe
  publication-title: J. Leukoc. Biol.
– volume: 267
  start-page: 14998
  year: 1992
  end-page: 15004
  article-title: Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins
  publication-title: J. Biol. Chem.
– volume: 97
  start-page: 889
  year: 1999
  end-page: 901
  article-title: RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides
  publication-title: Cell
– volume: 264
  start-page: 14935
  year: 1989
  end-page: 14939
  article-title: Protein phosphorylation associated with synergistic stimulation of neutrophils
  publication-title: J. Biol. Chem.
– volume: 398
  start-page: 73
  year: 2006
  end-page: 82
  article-title: Homocysteine stimulates phosphorylation of NADPH oxidase p47phox and p67phox subunits in monocytes via protein kinase Cβ activation
  publication-title: Biochem. J.
– volume: 122
  start-page: 293
  year: 2004
  end-page: 304
  article-title: Regulation of the NADPH‐oxidase complex of phagocytic leukocytes. Recent insights from structural biology, molecular genetics, and microscopy
  publication-title: Histochem. Cell Biol.
– volume: 269
  start-page: 24519
  year: 1994
  end-page: 24522
  article-title: The respiratory burst oxidase
  publication-title: J. Biol. Chem.
– volume: 81
  start-page: 520
  year: 2007
  end-page: 527
  article-title: Activation of RAGE induces elevated O2– generation by mononuclear phagocytes in diabetes
  publication-title: J. Leukoc. Biol.
– volume: 267
  start-page: 19901
  year: 1992
  end-page: 19906
  article-title: The translocation of respiratory burst oxidase components from cytosol to plasma membrane is regulated by guanine nucleotides and diacylglycerol
  publication-title: J. Biol. Chem.
– volume: 414
  start-page: 782
  year: 2001
  end-page: 787
  article-title: Global and societal implications of the diabetes epidemic
  publication-title: Nature
– volume: 173
  start-page: 2091
  year: 2004
  end-page: 2098
  article-title: A stable aspirin‐triggered lipoxin A4 analog blocks phosphorylation of leukocyte‐specific protein 1 in human neutrophils
  publication-title: J. Immunol.
– volume: 101
  start-page: 455
  year: 1998
  end-page: 463
  article-title: Neutrophils exposed to bacterial lipopolysaccharide upregulate NADPH oxidase assembly
  publication-title: J. Clin. Invest.
– volume: 280
  start-page: 37021
  year: 2005
  end-page: 37032
  article-title: Interleukin‐8‐induced priming of neutrophil oxidative burst requires sequential recruitment of NADPH oxidase components into lipid rafts
  publication-title: J. Biol. Chem.
– volume: 318
  start-page: 1315
  year: 1988
  end-page: 1321
  article-title: Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications
  publication-title: N. Engl. J. Med.
– volume: 78
  start-page: 862
  year: 2005
  end-page: 870
  article-title: Enhanced superoxide release and elevated protein kinase C activity in neutrophils from diabetic patients: association with periodontitis
  publication-title: J. Leukoc. Biol.
– volume: 116
  start-page: 2033
  year: 2006
  end-page: 2043
  article-title: A specific p47phox‐serine phosphorylated by convergent MAPKs mediates neutrophil NADPH oxidase priming at inflammatory sites
  publication-title: J. Clin. Invest.
– volume: 17
  start-page: 436
  year: 2001
  end-page: 443
  article-title: The AGE‐receptor in the pathogenesis of diabetic complications
  publication-title: Diabetes Metab. Res. Rev.
– volume: 106
  start-page: 473
  year: 2000
  end-page: 481
  article-title: Obesity and insulin resistance
  publication-title: J. Clin. Invest.
– volume: 17
  start-page: 189
  year: 2001
  end-page: 212
  article-title: The role of oxidative stress in the onset and progression of diabetes and its complications: a summary of a Congress Series sponsored by UNESCO‐MCBN, the American Diabetes Association and the German Diabetes Society
  publication-title: Diabetes Metab. Res. Rev.
– volume: 182
  start-page: 751
  year: 1995
  end-page: 758
  article-title: The p47phox mouse knock‐out model of chronic granulomatous disease
  publication-title: J. Exp. Med.
– volume: 281
  start-page: 13685
  year: 2006
  end-page: 13693
  article-title: Key role of Src kinase in S100B‐induced activation of the receptor for advanced glycation end products in vascular smooth muscle cells
  publication-title: J. Biol. Chem.
– volume: 16
  start-page: 264
  year: 1995
  end-page: 268
  article-title: Neutrophil priming: the cellular signals that say ‘amber’ but not ‘green'
  publication-title: Immunol. Today
– volume: 29
  start-page: 1420
  year: 2006
  end-page: 1432
  article-title: Diabetes and advanced glycoxidation end products
  publication-title: Diabetes Care
– volume: 274
  start-page: 33644
  year: 1999
  end-page: 33653
  article-title: Mechanism for phosphorylation‐induced activation of the phagocyte NADPH oxidase protein p47(phox). Triple replacement of serines 303, 304, and 328 with aspartates disrupts the SH3 domain‐mediated intramolecular interaction in p47(phox), thereby activating the oxidase
  publication-title: J. Biol. Chem.
– volume: 278
  start-page: 34834
  year: 2003
  end-page: 34844
  article-title: Regulation of cyclooxygenase‐2 expression in monocytes by ligation of the receptor for advanced glycation end products
  publication-title: J. Biol. Chem.
– volume: 286
  start-page: 199
  year: 2003
  end-page: 208
  article-title: Expression of GPI‐80, a β2‐integrin‐associated glycosylphosphati‐dylinositol‐anchored protein, requires neutrophil differentiation with dimethyl sulfoxide in HL‐60 cells
  publication-title: Exp. Cell Res.
– volume: 23
  start-page: 197
  year: 2005
  end-page: 223
  article-title: How neutrophils kill microbes
  publication-title: Annu. Rev. Immunol.
– volume: 24
  start-page: 104
  year: 2001
  end-page: 110
  article-title: Involvement of peripheral polymorphonuclear leukocytes in oxidative stress and inflammation in type 2 diabetic patients
  publication-title: Diabetes Care
– volume: 75
  start-page: 2458
  year: 1978
  end-page: 2462
  article-title: Terminal differentiation of human promyelocytic leukemia cells induced by dimethyl sulfoxide and other polar compounds
  publication-title: Proc. Natl. Acad. Sci. USA
– volume: 94
  start-page: 774
  year: 2005
  end-page: 793
  article-title: Differentiation of HL‐60 cells to granulocytes involves regulation of select diacylglycerol kinases (DGKs)
  publication-title: J. Cell. Biochem.
– volume: 26
  start-page: S5
  issue: Suppl. 1
  year: 2003
  end-page: S20
  article-title: Report of the expert committee on the diagnosis and classification of diabetes mellitus
  publication-title: Diabetes Care
– volume: 550
  start-page: 101
  year: 2003
  end-page: 106
  article-title: Lipid rafts determine efficiency of NADPH oxidase activation in neutrophils
  publication-title: FEBS Lett.
– volume: 6
  start-page: 345
  year: 1995
  end-page: 356
  article-title: Intracellular signaling in neutrophil priming and activation
  publication-title: Semin. Cell Biol.
– volume: 178
  start-page: 5253
  year: 2007
  end-page: 5261
  article-title: Free cholesterol alters lipid raft structure and function regulating neutrophil Ca2+ entry and respiratory burst: correlations with calcium channel raft trafficking
  publication-title: J. Immunol.
– volume: 64
  start-page: 959
  year: 1984
  end-page: 966
  article-title: Oxidants from phagocytes: agents of defense and destruction
  publication-title: Blood
– volume: 38
  start-page: 732
  year: 2006
  end-page: 739
  article-title: Generation of reactive oxygen species by endothelial and smooth muscle cells: influence of hyperglycemia and metformin
  publication-title: Horm. Metab. Res.
– volume: 95
  start-page: 233
  year: 2004
  end-page: 238
  article-title: Protein glycation: a firm link to endothelial cell dysfunction
  publication-title: Circ. Res.
– volume: 6
  start-page: 91
  year: 2001
  end-page: 98
  article-title: The relationship between periodontal diseases and diabetes: an overview
  publication-title: Ann. Periodontol.
– volume: 177
  start-page: 7250
  year: 2006
  end-page: 7256
  article-title: Chronic hyperglycemia predisposes to exaggerated inflammatory response and leukocyte dysfunction in Akita mice
  publication-title: J. Immunol.
– volume: 32
  start-page: 15
  year: 2006
  end-page: 29
  article-title: Role of diabetes in atherosclerotic pathogenesis. What have we learned from animal models?
  publication-title: Diabetes Metab.
– volume: 22
  start-page: 257
  year: 2006
  end-page: 273
  article-title: Diabetic neuropathy and oxidative stress
  publication-title: Diabetes Metab. Res. Rev.
– volume: 44
  start-page: 1973
  year: 2001
  end-page: 1988
  article-title: Vascular factors and metabolic interactions in the pathogenesis of diabetic neuropathy
  publication-title: Diabetologia
– volume: 149
  start-page: 969
  year: 1979
  end-page: 974
  article-title: Normal functional characteristics of cultured human promyelocytic leukemia cells (HL‐60) after induction of differentiation by dimethylsulfoxide
  publication-title: J. Exp. Med.
– volume: 6
  start-page: 125
  year: 2001
  end-page: 137
  article-title: Periodontitis and diabetes interrelationships: role of inflammation
  publication-title: Ann. Periodontol.
– volume: 6
  start-page: 313
  year: 2006
  end-page: 318
  article-title: Cardiovascular disease in diabetes
  publication-title: Mini Rev. Med. Chem.
– volume: 386
  start-page: 401
  year: 2005
  end-page: 416
  article-title: Activation and assembly of the NADPH oxidase: a structural perspective
  publication-title: Biochem. J.
– volume: 71
  start-page: 433
  year: 2002
  end-page: 444
  article-title: RAGE‐mediated neutrophil dysfunction is evoked by advanced glycation end products (AGEs)
  publication-title: J. Leukoc. Biol.
– volume: 100
  start-page: 2607
  year: 2002
  end-page: 2616
  article-title: Role of PI3‐kinase‐dependent Bad phosphorylation and altered transcription in cytokine‐mediated neutrophil survival
  publication-title: Blood
– volume: 274
  start-page: 31740
  year: 1999
  end-page: 31749
  article-title: N(∊)‐(carboxymethyl)lysine adducts of proteins are ligands for receptor for advanced glycation end products that activate cell signaling pathways and modulate gene expression
  publication-title: J. Biol. Chem.
– volume: 17
  start-page: 167
  year: 2005
  end-page: 175
  article-title: CD38 cleavage in fMLP‐ and IL‐8‐induced chemotaxis is dependent on p38 MAP kinase but independent of p44/42 MAP kinase
  publication-title: Cell. Signal.
– volume: 113
  start-page: 343
  year: 2003
  end-page: 355
  article-title: Molecular basis of phosphorylation‐induced activation of the NADPH oxidase
  publication-title: Cell
– volume: 74
  start-page: 66
  year: 2003
  end-page: 75
  article-title: Neutrophil‐mediated tissue injury in periodontal disease pathogenesis: findings from localized aggressive periodontitis
  publication-title: J. Periodontol.
– volume: 64
  start-page: 537
  year: 1998
  end-page: 545
  article-title: Activation of mitogen‐activated protein kinase cascades during priming of human neutrophils by TNF‐α and GM‐CSF
  publication-title: J. Leukoc. Biol.
– volume: 341
  start-page: 1127
  year: 1999
  end-page: 1133
  article-title: Nephropathy in patients with type 2 diabetes mellitus
  publication-title: N. Engl. J. Med.
– volume: 267
  start-page: 14987
  year: 1992
  end-page: 14997
  article-title: Isolation and characterization of two binding proteins for advanced glycosylation end products from bovine lung which are present on the endothelial cell surface
  publication-title: J. Biol. Chem.
– volume: 116
  start-page: 2033
  year: 2006
  ident: 2023032712571963600_
  article-title: A specific p47phox-serine phosphorylated by convergent MAPKs mediates neutrophil NADPH oxidase priming at inflammatory sites
  publication-title: J. Clin. Invest.
  doi: 10.1172/JCI27544
  contributor:
    fullname: Dang
– volume: 279
  start-page: 6643
  year: 2004
  ident: 2023032712571963600_
  article-title: High glucose enhances interleukin-6-induced vascular endothelial growth factor 165 expression via activation of gp130-mediated p44/42 MAPK-CCAAT/enhancer binding protein signaling in gingival fibroblasts
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M311688200
  contributor:
    fullname: Omori
– volume: 113
  start-page: 343
  year: 2003
  ident: 2023032712571963600_
  article-title: Molecular basis of phosphorylation-induced activation of the NADPH oxidase
  publication-title: Cell
  doi: 10.1016/S0092-8674(03)00314-3
  contributor:
    fullname: Groemping
– volume: 78
  start-page: 862
  year: 2005
  ident: 2023032712571963600_
  article-title: Enhanced superoxide release and elevated protein kinase C activity in neutrophils from diabetic patients: association with periodontitis
  publication-title: J. Leukoc. Biol.
  doi: 10.1189/jlb.1004583
  contributor:
    fullname: Karima
– volume: 267
  start-page: 19901
  year: 1992
  ident: 2023032712571963600_
  article-title: The translocation of respiratory burst oxidase components from cytosol to plasma membrane is regulated by guanine nucleotides and diacylglycerol
  publication-title: J. Biol. Chem.
  doi: 10.1016/S0021-9258(19)88641-6
  contributor:
    fullname: Park
– volume: 267
  start-page: 14998
  year: 1992
  ident: 2023032712571963600_
  article-title: Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins
  publication-title: J. Biol. Chem.
  doi: 10.1016/S0021-9258(18)42138-2
  contributor:
    fullname: Neeper
– volume: 17
  start-page: 189
  year: 2001
  ident: 2023032712571963600_
  article-title: The role of oxidative stress in the onset and progression of diabetes and its complications: a summary of a Congress Series sponsored by UNESCO-MCBN, the American Diabetes Association and the German Diabetes Society
  publication-title: Diabetes Metab. Res. Rev.
  doi: 10.1002/dmrr.196
  contributor:
    fullname: Rosen
– volume: 259
  start-page: 3771
  year: 1984
  ident: 2023032712571963600_
  article-title: Development of the superoxide-generating system during differentiation of the HL-60 human promyelocytic leukemia cell line
  publication-title: J. Biol. Chem.
  doi: 10.1016/S0021-9258(17)43161-9
  contributor:
    fullname: Newburger
– volume: 77
  start-page: 598
  year: 2005
  ident: 2023032712571963600_
  article-title: Myeloperoxidase: friend and foe
  publication-title: J. Leukoc. Biol.
  doi: 10.1189/jlb.1204697
  contributor:
    fullname: Klebanoff
– volume: 6
  start-page: 345
  year: 1995
  ident: 2023032712571963600_
  article-title: Intracellular signaling in neutrophil priming and activation
  publication-title: Semin. Cell Biol.
  doi: 10.1016/S1043-4682(05)80005-4
  contributor:
    fullname: Downey
– volume: 274
  start-page: 33644
  year: 1999
  ident: 2023032712571963600_
  article-title: Mechanism for phosphorylation-induced activation of the phagocyte NADPH oxidase protein p47(phox). Triple replacement of serines 303, 304, and 328 with aspartates disrupts the SH3 domain-mediated intramolecular interaction in p47(phox), thereby activating the oxidase
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.274.47.33644
  contributor:
    fullname: Ago
– volume: 26
  start-page: S5
  issue: Suppl. 1
  year: 2003
  ident: 2023032712571963600_
  article-title: Report of the expert committee on the diagnosis and classification of diabetes mellitus
  publication-title: Diabetes Care
  doi: 10.2337/diacare.26.2007.S5
  contributor:
    fullname: Expert Committee on the Diagnosis and Classification of Diabetes Mellitus
– volume: 6
  start-page: 125
  year: 2001
  ident: 2023032712571963600_
  article-title: Periodontitis and diabetes interrelationships: role of inflammation
  publication-title: Ann. Periodontol.
  doi: 10.1902/annals.2001.6.1.125
  contributor:
    fullname: Iacopino
– volume: 61
  start-page: 3137
  year: 1993
  ident: 2023032712571963600_
  article-title: Calcium-dependent protein kinase C activity of neutrophils in localized juvenile periodontitis
  publication-title: Infect. Immun.
  doi: 10.1128/iai.61.8.3137-3142.1993
  contributor:
    fullname: Kurihara
– volume: 6
  start-page: 313
  year: 2006
  ident: 2023032712571963600_
  article-title: Cardiovascular disease in diabetes
  publication-title: Mini Rev. Med. Chem.
  doi: 10.2174/138955706776073501
  contributor:
    fullname: Yamagishi
– volume: 38
  start-page: 732
  year: 2006
  ident: 2023032712571963600_
  article-title: Generation of reactive oxygen species by endothelial and smooth muscle cells: influence of hyperglycemia and metformin
  publication-title: Horm. Metab. Res.
  doi: 10.1055/s-2006-955084
  contributor:
    fullname: Bellin
– volume: 93
  start-page: 1464
  year: 1999
  ident: 2023032712571963600_
  article-title: NADPH oxidase: an update
  publication-title: Blood
  doi: 10.1182/blood.V93.5.1464
  contributor:
    fullname: Babior
– volume: 414
  start-page: 782
  year: 2001
  ident: 2023032712571963600_
  article-title: Global and societal implications of the diabetes epidemic
  publication-title: Nature
  doi: 10.1038/414782a
  contributor:
    fullname: Zimmet
– volume: 177
  start-page: 7250
  year: 2006
  ident: 2023032712571963600_
  article-title: Chronic hyperglycemia predisposes to exaggerated inflammatory response and leukocyte dysfunction in Akita mice
  publication-title: J. Immunol.
  doi: 10.4049/jimmunol.177.10.7250
  contributor:
    fullname: Gyurko
– volume: 17
  start-page: 436
  year: 2001
  ident: 2023032712571963600_
  article-title: The AGE-receptor in the pathogenesis of diabetic complications
  publication-title: Diabetes Metab. Res. Rev.
  doi: 10.1002/dmrr.233
  contributor:
    fullname: Vlassara
– volume: 122
  start-page: 293
  year: 2004
  ident: 2023032712571963600_
  article-title: Regulation of the NADPH-oxidase complex of phagocytic leukocytes. Recent insights from structural biology, molecular genetics, and microscopy
  publication-title: Histochem. Cell Biol.
  doi: 10.1007/s00418-004-0672-2
  contributor:
    fullname: Robinson
– volume: 550
  start-page: 101
  year: 2003
  ident: 2023032712571963600_
  article-title: Lipid rafts determine efficiency of NADPH oxidase activation in neutrophils
  publication-title: FEBS Lett.
  doi: 10.1016/S0014-5793(03)00845-7
  contributor:
    fullname: Shao
– volume: 97
  start-page: 889
  year: 1999
  ident: 2023032712571963600_
  article-title: RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides
  publication-title: Cell
  doi: 10.1016/S0092-8674(00)80801-6
  contributor:
    fullname: Hofmann
– volume: 278
  start-page: 34834
  year: 2003
  ident: 2023032712571963600_
  article-title: Regulation of cyclooxygenase-2 expression in monocytes by ligation of the receptor for advanced glycation end products
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M302828200
  contributor:
    fullname: Shanmugam
– volume: 274
  start-page: 31740
  year: 1999
  ident: 2023032712571963600_
  article-title: N(∊)-(carboxymethyl)lysine adducts of proteins are ligands for receptor for advanced glycation end products that activate cell signaling pathways and modulate gene expression
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.274.44.31740
  contributor:
    fullname: Kislinger
– volume: 32
  start-page: 15
  year: 2006
  ident: 2023032712571963600_
  article-title: Role of diabetes in atherosclerotic pathogenesis. What have we learned from animal models?
  publication-title: Diabetes Metab.
  doi: 10.1016/S1262-3636(07)70243-4
  contributor:
    fullname: Renard
– volume: 173
  start-page: 2091
  year: 2004
  ident: 2023032712571963600_
  article-title: A stable aspirin-triggered lipoxin A4 analog blocks phosphorylation of leukocyte-specific protein 1 in human neutrophils
  publication-title: J. Immunol.
  doi: 10.4049/jimmunol.173.3.2091
  contributor:
    fullname: Ohira
– volume: 398
  start-page: 73
  year: 2006
  ident: 2023032712571963600_
  article-title: Homocysteine stimulates phosphorylation of NADPH oxidase p47phox and p67phox subunits in monocytes via protein kinase Cβ activation
  publication-title: Biochem. J.
  doi: 10.1042/BJ20051810
  contributor:
    fullname: Siow
– volume: 64
  start-page: 537
  year: 1998
  ident: 2023032712571963600_
  article-title: Activation of mitogen-activated protein kinase cascades during priming of human neutrophils by TNF-α and GM-CSF
  publication-title: J. Leukoc. Biol.
  doi: 10.1002/jlb.64.4.537
  contributor:
    fullname: McLeish
– volume: 106
  start-page: 473
  year: 2000
  ident: 2023032712571963600_
  article-title: Obesity and insulin resistance
  publication-title: J. Clin. Invest.
  doi: 10.1172/JCI10842
  contributor:
    fullname: Kahn
– volume: 280
  start-page: 37021
  year: 2005
  ident: 2023032712571963600_
  article-title: Interleukin-8-induced priming of neutrophil oxidative burst requires sequential recruitment of NADPH oxidase components into lipid rafts
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M506594200
  contributor:
    fullname: Guichard
– volume: 272
  start-page: 29502
  year: 1997
  ident: 2023032712571963600_
  article-title: Analysis of activation-induced conformational changes in p47phox using tryptophan fluorescence spectroscopy
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.272.47.29502
  contributor:
    fullname: Swain
– volume: 22
  start-page: 257
  year: 2006
  ident: 2023032712571963600_
  article-title: Diabetic neuropathy and oxidative stress
  publication-title: Diabetes Metab. Res. Rev.
  doi: 10.1002/dmrr.625
  contributor:
    fullname: Pop-Busui
– volume: 149
  start-page: 969
  year: 1979
  ident: 2023032712571963600_
  article-title: Normal functional characteristics of cultured human promyelocytic leukemia cells (HL-60) after induction of differentiation by dimethylsulfoxide
  publication-title: J. Exp. Med.
  doi: 10.1084/jem.149.4.969
  contributor:
    fullname: Collins
– volume: 61
  start-page: 1081
  year: 1978
  ident: 2023032712571963600_
  article-title: Superoxide generation by digitonin-stimulated guinea pig granulocytes. A basis for a continuous assay for monitoring superoxide production and for the study of the activation of the generating system
  publication-title: J. Clin. Invest.
  doi: 10.1172/JCI109007
  contributor:
    fullname: Cohen
– volume: 24
  start-page: 104
  year: 2001
  ident: 2023032712571963600_
  article-title: Involvement of peripheral polymorphonuclear leukocytes in oxidative stress and inflammation in type 2 diabetic patients
  publication-title: Diabetes Care
  doi: 10.2337/diacare.24.1.104
  contributor:
    fullname: Shurtz-Swirski
– volume: 269
  start-page: 24519
  year: 1994
  ident: 2023032712571963600_
  article-title: The respiratory burst oxidase
  publication-title: J. Biol. Chem.
  doi: 10.1016/S0021-9258(17)31418-7
  contributor:
    fullname: Chanock
– volume: 182
  start-page: 751
  year: 1995
  ident: 2023032712571963600_
  article-title: The p47phox mouse knock-out model of chronic granulomatous disease
  publication-title: J. Exp. Med.
  doi: 10.1084/jem.182.3.751
  contributor:
    fullname: Jackson
– volume: 29
  start-page: 1420
  year: 2006
  ident: 2023032712571963600_
  article-title: Diabetes and advanced glycoxidation end products
  publication-title: Diabetes Care
  doi: 10.2337/dc05-2096
  contributor:
    fullname: Huebschmann
– volume: 76
  start-page: 760
  year: 2004
  ident: 2023032712571963600_
  article-title: Structure and regulation of the neutrophil respiratory burst oxidase: comparison with nonphagocyte oxidases
  publication-title: J. Leukoc. Biol.
  doi: 10.1189/jlb.0404216
  contributor:
    fullname: Quinn
– volume: 44
  start-page: 1973
  year: 2001
  ident: 2023032712571963600_
  article-title: Vascular factors and metabolic interactions in the pathogenesis of diabetic neuropathy
  publication-title: Diabetologia
  doi: 10.1007/s001250100001
  contributor:
    fullname: Cameron
– volume: 109
  start-page: 33
  year: 2000
  ident: 2023032712571963600_
  article-title: Phagocytes and oxidative stress
  publication-title: Am. J. Med.
  doi: 10.1016/S0002-9343(00)00481-2
  contributor:
    fullname: Babior
– volume: 17
  start-page: 167
  year: 2005
  ident: 2023032712571963600_
  article-title: CD38 cleavage in fMLP- and IL-8-induced chemotaxis is dependent on p38 MAP kinase but independent of p44/42 MAP kinase
  publication-title: Cell. Signal.
  doi: 10.1016/j.cellsig.2004.06.008
  contributor:
    fullname: Fujita
– volume: 267
  start-page: 14987
  year: 1992
  ident: 2023032712571963600_
  article-title: Isolation and characterization of two binding proteins for advanced glycosylation end products from bovine lung which are present on the endothelial cell surface
  publication-title: J. Biol. Chem.
  doi: 10.1016/S0021-9258(18)42137-0
  contributor:
    fullname: Schmidt
– volume: 94
  start-page: 774
  year: 2005
  ident: 2023032712571963600_
  article-title: Differentiation of HL-60 cells to granulocytes involves regulation of select diacylglycerol kinases (DGKs)
  publication-title: J. Cell. Biochem.
  doi: 10.1002/jcb.20356
  contributor:
    fullname: Batista
– volume: 14
  start-page: 1521
  year: 1994
  ident: 2023032712571963600_
  article-title: Cellular receptors for advanced glycation end products. Implications for induction of oxidant stress and cellular dysfunction in the pathogenesis of vascular lesions
  publication-title: Arterioscler. Thromb.
  doi: 10.1161/01.ATV.14.10.1521
  contributor:
    fullname: Schmidt
– volume: 386
  start-page: 401
  year: 2005
  ident: 2023032712571963600_
  article-title: Activation and assembly of the NADPH oxidase: a structural perspective
  publication-title: Biochem. J.
  doi: 10.1042/BJ20041835
  contributor:
    fullname: Groemping
– volume: 108
  start-page: 949
  year: 2001
  ident: 2023032712571963600_
  article-title: The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses
  publication-title: J. Clin. Invest.
  doi: 10.1172/JCI200114002
  contributor:
    fullname: Schmidt
– volume: 341
  start-page: 1127
  year: 1999
  ident: 2023032712571963600_
  article-title: Nephropathy in patients with type 2 diabetes mellitus
  publication-title: N. Engl. J. Med.
  doi: 10.1056/NEJM199910073411506
  contributor:
    fullname: Ritz
– volume: 286
  start-page: 199
  year: 2003
  ident: 2023032712571963600_
  article-title: Expression of GPI-80, a β2-integrin-associated glycosylphosphati-dylinositol-anchored protein, requires neutrophil differentiation with dimethyl sulfoxide in HL-60 cells
  publication-title: Exp. Cell Res.
  doi: 10.1016/S0014-4827(03)00071-5
  contributor:
    fullname: Takeda
– volume: 10
  start-page: 33
  year: 1980
  ident: 2023032712571963600_
  article-title: Differentiation of human promyelocytic leukemia cells in vitro by 6-thio-guanine
  publication-title: Cancer Lett.
  doi: 10.1016/0304-3835(80)90062-2
  contributor:
    fullname: Papac
– volume: 192
  start-page: 1
  year: 2002
  ident: 2023032712571963600_
  article-title: Cellular response to oxidative stress: signaling for suicide and survival
  publication-title: J. Cell. Physiol.
  doi: 10.1002/jcp.10119
  contributor:
    fullname: Martindale
– volume: 101
  start-page: 455
  year: 1998
  ident: 2023032712571963600_
  article-title: Neutrophils exposed to bacterial lipopolysaccharide upregulate NADPH oxidase assembly
  publication-title: J. Clin. Invest.
  doi: 10.1172/JCI949
  contributor:
    fullname: DeLeo
– volume: 71
  start-page: 433
  year: 2002
  ident: 2023032712571963600_
  article-title: RAGE-mediated neutrophil dysfunction is evoked by advanced glycation end products (AGEs)
  publication-title: J. Leukoc. Biol.
  doi: 10.1189/jlb.71.3.433
  contributor:
    fullname: Collison
– volume: 95
  start-page: 233
  year: 2004
  ident: 2023032712571963600_
  article-title: Protein glycation: a firm link to endothelial cell dysfunction
  publication-title: Circ. Res.
  doi: 10.1161/01.RES.0000137876.28454.64
  contributor:
    fullname: Wautier
– volume: 16
  start-page: 264
  year: 1995
  ident: 2023032712571963600_
  article-title: Neutrophil priming: the cellular signals that say ‘amber’ but not ‘green’
  publication-title: Immunol. Today
  doi: 10.1016/0167-5699(95)80178-2
  contributor:
    fullname: Hallett
– volume: 64
  start-page: 959
  year: 1984
  ident: 2023032712571963600_
  article-title: Oxidants from phagocytes: agents of defense and destruction
  publication-title: Blood
  doi: 10.1182/blood.V64.5.959.959
  contributor:
    fullname: Babior
– volume: 74
  start-page: 66
  year: 2003
  ident: 2023032712571963600_
  article-title: Neutrophil-mediated tissue injury in periodontal disease pathogenesis: findings from localized aggressive periodontitis
  publication-title: J. Periodontol.
  doi: 10.1902/jop.2003.74.1.66
  contributor:
    fullname: Kantarci
– volume: 6
  start-page: 91
  year: 2001
  ident: 2023032712571963600_
  article-title: The relationship between periodontal diseases and diabetes: an overview
  publication-title: Ann. Periodontol.
  doi: 10.1902/annals.2001.6.1.91
  contributor:
    fullname: Soskolne
– volume: 264
  start-page: 14935
  year: 1989
  ident: 2023032712571963600_
  article-title: Protein phosphorylation associated with synergistic stimulation of neutrophils
  publication-title: J. Biol. Chem.
  doi: 10.1016/S0021-9258(18)63792-5
  contributor:
    fullname: Heyworth
– volume: 281
  start-page: 13685
  year: 2006
  ident: 2023032712571963600_
  article-title: Key role of Src kinase in S100B-induced activation of the receptor for advanced glycation end products in vascular smooth muscle cells
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M511425200
  contributor:
    fullname: Reddy
– volume: 81
  start-page: 520
  year: 2007
  ident: 2023032712571963600_
  article-title: Activation of RAGE induces elevated O2– generation by mononuclear phagocytes in diabetes
  publication-title: J. Leukoc. Biol.
  doi: 10.1189/jlb.0406262
  contributor:
    fullname: Ding
– volume: 318
  start-page: 1315
  year: 1988
  ident: 2023032712571963600_
  article-title: Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications
  publication-title: N. Engl. J. Med.
  doi: 10.1056/NEJM198805193182007
  contributor:
    fullname: Brownlee
– volume: 100
  start-page: 2607
  year: 2002
  ident: 2023032712571963600_
  article-title: Role of PI3-kinase-dependent Bad phosphorylation and altered transcription in cytokine-mediated neutrophil survival
  publication-title: Blood
  doi: 10.1182/blood-2001-11-0122
  contributor:
    fullname: Cowburn
– volume: 23
  start-page: 197
  year: 2005
  ident: 2023032712571963600_
  article-title: How neutrophils kill microbes
  publication-title: Annu. Rev. Immunol.
  doi: 10.1146/annurev.immunol.23.021704.115653
  contributor:
    fullname: Segal
– volume: 178
  start-page: 5253
  year: 2007
  ident: 2023032712571963600_
  article-title: Free cholesterol alters lipid raft structure and function regulating neutrophil Ca2+ entry and respiratory burst: correlations with calcium channel raft trafficking
  publication-title: J. Immunol.
  doi: 10.4049/jimmunol.178.8.5253
  contributor:
    fullname: Kannan
– volume: 75
  start-page: 2458
  year: 1978
  ident: 2023032712571963600_
  article-title: Terminal differentiation of human promyelocytic leukemia cells induced by dimethyl sulfoxide and other polar compounds
  publication-title: Proc. Natl. Acad. Sci. USA
  doi: 10.1073/pnas.75.5.2458
  contributor:
    fullname: Collins
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Snippet Hyperglycemia associated with diabetes mellitus results in the priming of neutrophils leading to oxidative stress that is, in part, responsible for diabetic...
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SubjectTerms Adult
cell activation
Cell Membrane - drug effects
Cell Membrane - enzymology
Diabetes Mellitus - enzymology
Diabetes Mellitus - pathology
Female
Flavonoids - pharmacology
HL-60 Cells
Humans
inflammation
Male
Mitogen-Activated Protein Kinase 1 - metabolism
Mitogen-Activated Protein Kinase 3 - metabolism
N-Formylmethionine Leucyl-Phenylalanine - pharmacology
NADPH Oxidases - metabolism
Neutrophils - drug effects
Neutrophils - enzymology
Neutrophils - pathology
Oxidative Stress
p38 Mitogen-Activated Protein Kinases - metabolism
Phosphorylation - drug effects
Protein Transport - drug effects
Receptor for Advanced Glycation End Products
Receptors, Immunologic - metabolism
Receptors, Signal Transduction, and Genes
Respiratory Burst - drug effects
signal transduction
Superoxides - metabolism
Title Priming of neutrophil oxidative burst in diabetes requires preassembly of the NADPH oxidase
URI http://www.jleukbio.org/content/84/1/292.abstract
https://onlinelibrary.wiley.com/doi/abs/10.1189%2Fjlb.1207832
https://www.ncbi.nlm.nih.gov/pubmed/18390927
https://search.proquest.com/docview/20879405
https://search.proquest.com/docview/20894720
https://pubmed.ncbi.nlm.nih.gov/PMC2774791
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