Epigenetic mechanisms in glioblastoma multiforme - Nagarajan, Raman P.; Costello, Joseph F. (Seminars in cancer biology, 2009)
Keywords: Biomarkers, Tumor - metabolism; Central Nervous System Neoplasms - drug therapy; Central Nervous System Neoplasms - genetics; Central Nervous System Neoplasms - metabolism; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases - metabolism; DNA Methylation; DNA Modification Methylases - genetics; DNA Modification Methylases - metabolism; DNA Repair Enzymes - genetics; DNA Repair Enzymes - metabolism; Enzyme Inhibitors - therapeutic use; Epigenesis, Genetic - drug effects; Epigenetics; Gene Expression Regulation, Neoplastic; Gene Silencing - physiology; Glioblastoma; Glioblastoma - drug therapy; Glioblastoma - genetics; Glioblastoma - metabolism; Hematology, Oncology and Palliative Medicine; Histone Deacetylases - metabolism; Histones - metabolism; Humans; MicroRNAs - metabolism; Polycomb-Group Proteins; Promoter Regions, Genetic; Repressor Proteins - metabolism; Tumor Suppressor Proteins - genetics; Tumor Suppressor Proteins - metabolism; SAHA; TSA; CGI; MGMT; LOI; Glioblastoma; ICF; TIC; 5-aza; DNMT; GBM; Epigenetics; DNA methylation; HDACi; HDAC; glioblastoma multiforme; trichostatin A; suberoylanilide hydroxamic acid; loss of imprinting; immunodeficiency, centromere instability and facial anomalies; CpG island; O6-methylguanine-DNA methyltransferase; histone deacetylase inhibitor; tumor initiating cell; histone deacetylase; DNA methyltransferase; 5-aza-2′-deoxycytidine