Vaginal lactobacilli inhibit growth and hyphae formation of Candida albicans

• Published in: Scientific reports Vol. 9; no. 1; p. 8121
• Main Authors: Jang, Sung Jae, Lee, Kyeongju, Kwon, Bomi, You, Hyun Ju, Ko, GwangPyo
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 31.05.2019; Nature Publishing Group
• Subjects: 13; 38; 38/77; 631/326/22/1292; 631/326/2522; 64; 64/60; Adult; Aged; Animals; Antifungal activity; Antifungal agents; Candida; Candida albicans; Candida albicans - growth & development; Candida albicans - pathogenicity; Candidiasis; Candidiasis, Vulvovaginal - microbiology; Female; Heat inactivation; Humanities and Social Sciences; Humans; Hydrogen peroxide; Hydrogen Peroxide - chemistry; Hypersensitivity; Hyphae; Hyphae - growth & development; Inactivation; Lactic acid; Lactobacillus; Lactobacillus - physiology; Lactobacillus crispatus - physiology; Lactobacillus fermentum - physiology; Mice; Microbiota; Middle Aged; multidisciplinary; Proteolysis; Republic of Korea; RNA, Ribosomal, 16S - isolation & purification; Science; Science (multidisciplinary); Vagina; Vagina - microbiology; Republic of Korea

Lactobacillus species are the predominant vaginal microbiota found in healthy women of reproductive age and help to prevent pathogen infection by producing lactic acid, H 2 O 2 and anti-microbial compounds. Identification of novel vaginal Lactobacillus isolates that exhibit efficient colonisation an...