The clinical application of high-resolution peripheral computed tomography (HR-pQCT) in adults: state of the art and future directions

• Published in: Osteoporosis international Vol. 32; no. 8; pp. 1465 - 1485
• Main Authors: van den Bergh, J.P., Szulc, P., Cheung, A.M., Bouxsein, M., Engelke, K., Chapurlat, R.
• Format: Journal Article
• Language: English
• Published: London Springer London 01.08.2021; Springer Nature B.V; Springer Verlag
• Subjects: Adult; Aged; Bone Density; Bone diseases; Bone Diseases, Metabolic; Bone healing; Bone imaging; Bone strength; Cartilage; Clinical medicine; Computed tomography; Dual energy X-ray absorptiometry; Endocrinology; Fractures; Fractures, Bone - diagnostic imaging; Humans; Life Sciences; Medicine; Medicine & Public Health; Metabolism; Orthopedics; Osteoporosis; Osteoporosis - diagnostic imaging; Osteoporosis - drug therapy; Pathophysiology; Patients; Position Paper; Predictions; Radius; Reviews; Rheumatology; Subchondral bone; Tomography, X-Ray Computed; Osteoporosis; High-resolution peripheral quantitative computed tomography (HR-pQCT); Metabolic bone disorders; Fracture risk prediction; Reference data

High-resolution peripheral computed tomography (HR-pQCT) was developed to image bone microarchitecture in vivo at peripheral skeletal sites. Since the introduction of HR-pQCT in 2005, clinical research to gain insight into pathophysiology of skeletal fragility and to improve prediction of fractures...