A Prospective Birth Cohort Study on Early Childhood Lead Levels and Attention Deficit Hyperactivity Disorder: New Insight on Sex Differences

• Published in: The Journal of pediatrics Vol. 199; pp. 124 - 131.e8
• Main Authors: Ji, Yuelong, Hong, Xiumei, Wang, Guoying, Chatterjee, Nilanjan, Riley, Anne W., Lee, Li-Ching, Surkan, Pamela J., Bartell, Tami R., Zuckerman, Barry, Wang, Xiaobin
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.08.2018
• Subjects: Attention Deficit Disorder with Hyperactivity - etiology; Case-Control Studies; Child; Child, Preschool; Environmental Exposure - adverse effects; Environmental Exposure - analysis; Environmental Pollutants - blood; Environmental Pollutants - toxicity; Environmental Pollution - adverse effects; Female; Follow-Up Studies; HDL; Humans; Infant; Lead - blood; Lead - toxicity; Logistic Models; Male; neurodevelopment disorder; Pregnancy; Prenatal Exposure Delayed Effects - etiology; Prospective Studies; Risk Factors; Sex Factors; stress; HDL; stress; ADHD; BBC; MLR; CDC; NT; BMC; EMR; ICD; neurodevelopment disorder; DSM

To investigate the prospective associations between early childhood lead exposure and subsequent risk of attention deficit hyperactivity disorder (ADHD) in childhood and its potential effect modifiers. We analyzed data from 1479 mother–infant pairs (299 ADHD, 1180 neurotypical) in the Boston Birth C...