Pediatric Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): Clinical Presentation, Infectivity, and Immune Responses

• Published in: The Journal of pediatrics Vol. 227; pp. 45 - 52.e5
• Main Authors: Yonker, Lael M., Neilan, Anne M., Bartsch, Yannic, Patel, Ankit B., Regan, James, Arya, Puneeta, Gootkind, Elizabeth, Park, Grace, Hardcastle, Margot, St. John, Anita, Appleman, Lori, Chiu, Michelle L., Fialkowski, Allison, De la Flor, Denis, Lima, Rosiane, Bordt, Evan A., Yockey, Laura J., D'Avino, Paolo, Fischinger, Stephanie, Shui, Jessica E., Lerou, Paul H., Bonventre, Joseph V., Yu, Xu G., Ryan, Edward T., Bassett, Ingrid V., Irimia, Daniel, Edlow, Andrea G., Alter, Galit, Li, Jonathan Z., Fasano, Alessio
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.12.2020
• Subjects: Adolescent; Age Factors; Child; Child, Preschool; Comorbidity; COVID-19 - diagnosis; COVID-19 - epidemiology; COVID-19 - immunology; COVID-19 - transmission; COVID-19 Testing; Female; Humans; Infant; Infant, Newborn; Male; Massachusetts - epidemiology; Original; Pandemics; Severity of Illness Index; Viral Load; Young Adult; Massachusetts; COVID-19; ACE2; IPO8; MIS-C; SARS-CoV-2; RSV; RBD; IRB; NT-proBNB; MGH

As schools plan for re-opening, understanding the potential role children play in the coronavirus infectious disease 2019 (COVID-19) pandemic and the factors that drive severe illness in children is critical. Children ages 0-22 years with suspected severe acute respiratory syndrome coronavirus 2 (SA...