Genetic regulation of disease risk and endometrial gene expression highlights potential target genes for endometriosis and polycystic ovarian syndrome

Gene expression varies markedly across the menstrual cycle and expression levels for many genes are under genetic control. We analyzed gene expression and mapped expression quantitative trait loci (eQTLs) in endometrial tissue samples from 229 women and then analyzed the overlap of endometrial eQTL...

Full description

Saved in:
Bibliographic Details
Published inScientific reports Vol. 8; no. 1; pp. 11424 - 19
Main Authors Fung, Jenny N., Mortlock, Sally, Girling, Jane E., Holdsworth-Carson, Sarah J., Teh, Wan Tinn, Zhu, Zhihong, Lukowski, Samuel W., McKinnon, Brett D., McRae, Allan, Yang, Jian, Healey, Martin, Powell, Joseph E., Rogers, Peter A. W., Montgomery, Grant W.
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group UK 30.07.2018
Nature Publishing Group
Subjects
38
38/39
45
45/61
631/114/2407
631/208/200
Biological control
Chromosome 1
Chromosome 12
DNA probes
Endometriosis
Endometrium
Gene expression
Gene mapping
Gene silencing
Genetic control
Genetic effects
Genotype & phenotype
Health risks
Humanities and Social Sciences
Menstrual cycle
multidisciplinary
Polycystic ovary syndrome
Probes
Quantitative trait loci
Science
Science (multidisciplinary)
Online AccessGet full text

Cover

Abstract Gene expression varies markedly across the menstrual cycle and expression levels for many genes are under genetic control. We analyzed gene expression and mapped expression quantitative trait loci (eQTLs) in endometrial tissue samples from 229 women and then analyzed the overlap of endometrial eQTL signals with genomic regions associated with endometriosis and other reproductive traits. We observed a total of 45,923 cis -eQTLs for 417 unique genes and 2,968 trans -eQTLs affecting 82 unique genes. Two eQTLs were located in known risk regions for endometriosis including LINC00339 on chromosome 1 and VEZT on chromosome 12 and there was evidence for eQTLs that may be target genes in genomic regions associated with other reproductive diseases. Dynamic changes in expression of individual genes across cycle include alterations in both mean expression and transcriptional silencing. Significant effects of cycle stage on mean expression levels were observed for (2,427/15,262) probes with detectable expression in at least 90% of samples and for (2,877/9,626) probes expressed in some, but not all samples. Pathway analysis supports similar biological control of both altered expression levels and transcriptional silencing. Taken together, these data identify strong genetic effects on genes with diverse functions in human endometrium and provide a platform for better understanding genetic effects on endometrial-related pathologies.
AbstractList Gene expression varies markedly across the menstrual cycle and expression levels for many genes are under genetic control. We analyzed gene expression and mapped expression quantitative trait loci (eQTLs) in endometrial tissue samples from 229 women and then analyzed the overlap of endometrial eQTL signals with genomic regions associated with endometriosis and other reproductive traits. We observed a total of 45,923 cis-eQTLs for 417 unique genes and 2,968 trans-eQTLs affecting 82 unique genes. Two eQTLs were located in known risk regions for endometriosis including LINC00339 on chromosome 1 and VEZT on chromosome 12 and there was evidence for eQTLs that may be target genes in genomic regions associated with other reproductive diseases. Dynamic changes in expression of individual genes across cycle include alterations in both mean expression and transcriptional silencing. Significant effects of cycle stage on mean expression levels were observed for (2,427/15,262) probes with detectable expression in at least 90% of samples and for (2,877/9,626) probes expressed in some, but not all samples. Pathway analysis supports similar biological control of both altered expression levels and transcriptional silencing. Taken together, these data identify strong genetic effects on genes with diverse functions in human endometrium and provide a platform for better understanding genetic effects on endometrial-related pathologies.
Gene expression varies markedly across the menstrual cycle and expression levels for many genes are under genetic control. We analyzed gene expression and mapped expression quantitative trait loci (eQTLs) in endometrial tissue samples from 229 women and then analyzed the overlap of endometrial eQTL signals with genomic regions associated with endometriosis and other reproductive traits. We observed a total of 45,923 cis -eQTLs for 417 unique genes and 2,968 trans -eQTLs affecting 82 unique genes. Two eQTLs were located in known risk regions for endometriosis including LINC00339 on chromosome 1 and VEZT on chromosome 12 and there was evidence for eQTLs that may be target genes in genomic regions associated with other reproductive diseases. Dynamic changes in expression of individual genes across cycle include alterations in both mean expression and transcriptional silencing. Significant effects of cycle stage on mean expression levels were observed for (2,427/15,262) probes with detectable expression in at least 90% of samples and for (2,877/9,626) probes expressed in some, but not all samples. Pathway analysis supports similar biological control of both altered expression levels and transcriptional silencing. Taken together, these data identify strong genetic effects on genes with diverse functions in human endometrium and provide a platform for better understanding genetic effects on endometrial-related pathologies.
Abstract Gene expression varies markedly across the menstrual cycle and expression levels for many genes are under genetic control. We analyzed gene expression and mapped expression quantitative trait loci (eQTLs) in endometrial tissue samples from 229 women and then analyzed the overlap of endometrial eQTL signals with genomic regions associated with endometriosis and other reproductive traits. We observed a total of 45,923 cis -eQTLs for 417 unique genes and 2,968 trans -eQTLs affecting 82 unique genes. Two eQTLs were located in known risk regions for endometriosis including LINC00339 on chromosome 1 and VEZT on chromosome 12 and there was evidence for eQTLs that may be target genes in genomic regions associated with other reproductive diseases. Dynamic changes in expression of individual genes across cycle include alterations in both mean expression and transcriptional silencing. Significant effects of cycle stage on mean expression levels were observed for (2,427/15,262) probes with detectable expression in at least 90% of samples and for (2,877/9,626) probes expressed in some, but not all samples. Pathway analysis supports similar biological control of both altered expression levels and transcriptional silencing. Taken together, these data identify strong genetic effects on genes with diverse functions in human endometrium and provide a platform for better understanding genetic effects on endometrial-related pathologies.
ArticleNumber 11424
Author McRae, Allan
Girling, Jane E.
Fung, Jenny N.
Powell, Joseph E.
Teh, Wan Tinn
Montgomery, Grant W.
Lukowski, Samuel W.
Yang, Jian
Zhu, Zhihong
Healey, Martin
McKinnon, Brett D.
Rogers, Peter A. W.
Mortlock, Sally
Holdsworth-Carson, Sarah J.
Author_xml – sequence: 1
  givenname: Jenny N.
  surname: Fung
  fullname: Fung, Jenny N.
  email: j.fung1@uq.edu.au
  organization: The Institute for Molecular Bioscience, The University of Queensland
– sequence: 2
  givenname: Sally
  surname: Mortlock
  fullname: Mortlock, Sally
  organization: The Institute for Molecular Bioscience, The University of Queensland
– sequence: 3
  givenname: Jane E.
  surname: Girling
  fullname: Girling, Jane E.
  organization: Gynaecology Research Centre, The University of Melbourne, Department of Obstetrics and Gynaecology, Royal Women’s Hospital, Department of Anatomy, University of Otago
– sequence: 4
  givenname: Sarah J.
  surname: Holdsworth-Carson
  fullname: Holdsworth-Carson, Sarah J.
  organization: Gynaecology Research Centre, The University of Melbourne, Department of Obstetrics and Gynaecology, Royal Women’s Hospital
– sequence: 5
  givenname: Wan Tinn
  surname: Teh
  fullname: Teh, Wan Tinn
  organization: Gynaecology Research Centre, The University of Melbourne, Department of Obstetrics and Gynaecology, Royal Women’s Hospital
– sequence: 6
  givenname: Zhihong
  surname: Zhu
  fullname: Zhu, Zhihong
  organization: The Institute for Molecular Bioscience, The University of Queensland
– sequence: 7
  givenname: Samuel W.
  orcidid: 0000-0002-8598-7902
  surname: Lukowski
  fullname: Lukowski, Samuel W.
  organization: The Institute for Molecular Bioscience, The University of Queensland
– sequence: 8
  givenname: Brett D.
  surname: McKinnon
  fullname: McKinnon, Brett D.
  organization: The Institute for Molecular Bioscience, The University of Queensland, Department of Obstetrics and Gynaecology, University hospital of Berne
– sequence: 9
  givenname: Allan
  surname: McRae
  fullname: McRae, Allan
  organization: The Institute for Molecular Bioscience, The University of Queensland
– sequence: 10
  givenname: Jian
  orcidid: 0000-0003-2001-2474
  surname: Yang
  fullname: Yang, Jian
  organization: The Institute for Molecular Bioscience, The University of Queensland
– sequence: 11
  givenname: Martin
  surname: Healey
  fullname: Healey, Martin
  organization: Gynaecology Research Centre, The University of Melbourne, Department of Obstetrics and Gynaecology, Royal Women’s Hospital
– sequence: 12
  givenname: Joseph E.
  surname: Powell
  fullname: Powell, Joseph E.
  organization: The Institute for Molecular Bioscience, The University of Queensland
– sequence: 13
  givenname: Peter A. W.
  surname: Rogers
  fullname: Rogers, Peter A. W.
  organization: Gynaecology Research Centre, The University of Melbourne, Department of Obstetrics and Gynaecology, Royal Women’s Hospital
– sequence: 14
  givenname: Grant W.
  orcidid: 0000-0002-4140-8139
  surname: Montgomery
  fullname: Montgomery, Grant W.
  organization: The Institute for Molecular Bioscience, The University of Queensland
BackLink https://www.ncbi.nlm.nih.gov/pubmed/30061686$$D View this record in MEDLINE/PubMed
BookMark eNp9kc1u1TAQhS1UREvpC7BAltiwCdj5ceINEqqgrVSJDawtxxnnuuTaweNbNS_C8-LcW9rCAkuWLc03Z87ovCRHPngg5DVn7zmrug9Y80Z2BeNdUcpalMXyjJyUrG6KsirLoyf_Y3KGeMPyaTLJ5QtyXDEmuOjECfl1AR6SMzTCuJt0csHTYOngEDQCjQ5_UO0HCn4IW0jR6YmOuYXC3RwBceU3btxM-Sakc0jg0wolHUdIexapDfFRIaDDveYcpsUsuE4PtzpLe4qLH2LGXpHnVk8IZ_fvKfn-5fO388vi-uvF1fmn68I0bZsKMfSGs940Utja9L2UEmzJLR_A1qyRurFDJQ2XlexY29jeyK7mpm6N6QW0vDolHw-6867fwmCy-agnNUe31XFRQTv1d8W7jRrDrRJMNHW5Cry7F4jh5w4wqa1DA9OkPYQdqpJ1rMtWOpHRt_-gN2EXfV4vU62UVVPLOlPlgTIxIEawD2Y4U2vy6pC8ysmrffJqyU1vnq7x0PIn5wxUBwBzyY8QH2f_R_Y3RpfBZw
CitedBy_id crossref_primary_10_3389_frph_2021_795464
crossref_primary_10_1016_j_rbmo_2021_07_007
crossref_primary_10_1186_s13148_021_01103_8
crossref_primary_10_1071_RD20281
crossref_primary_10_1016_j_jmig_2019_10_020
crossref_primary_10_1186_s13148_019_0648_7
crossref_primary_10_3389_fgene_2019_00766
crossref_primary_10_1111_aji_13590
crossref_primary_10_3390_cells12131736
crossref_primary_10_1093_carcin_bgab057
crossref_primary_10_1007_s10815_024_03077_x
crossref_primary_10_3390_ijms22147297
crossref_primary_10_3390_ijms20081842
crossref_primary_10_1038_s41588_023_01323_z
crossref_primary_10_3389_fimmu_2021_788315
crossref_primary_10_3390_ijms22116083
crossref_primary_10_1016_j_genrep_2020_100716
crossref_primary_10_1038_s41467_023_41979_z
crossref_primary_10_1111_jog_15549
crossref_primary_10_1016_j_xcrm_2022_100542
crossref_primary_10_1136_bmjopen_2021_050844
crossref_primary_10_1093_molehr_gaz006
crossref_primary_10_7759_cureus_55059
crossref_primary_10_1093_humrep_dez279
crossref_primary_10_1016_j_rbmo_2020_03_015
crossref_primary_10_1016_j_ejogrb_2020_10_017
crossref_primary_10_1186_s12916_023_03166_1
crossref_primary_10_3389_fendo_2019_00763
crossref_primary_10_1038_s41598_022_13488_4
crossref_primary_10_1093_molehr_gaab018
crossref_primary_10_1002_jcb_28330
crossref_primary_10_3390_jcm9051309
crossref_primary_10_1038_s42003_023_05070_z
crossref_primary_10_1093_molehr_gaab010
crossref_primary_10_56093_ijans_v90i5_104611
crossref_primary_10_1093_molehr_gaaa082
crossref_primary_10_1038_s42003_022_03541_3
Cites_doi 10.1126/science.1262110
10.1038/ng.2272
10.3892/ijmm.2013.1536
10.1038/s41598-017-10098-3
10.1210/jcem.87.4.8539
10.1101/gr.6981507
10.1016/j.ygyno.2014.04.009
10.1056/NEJMcp1000274
10.1016/j.tox.2004.07.005
10.1038/ncomms15539
10.1007/s00018-004-4435-y
10.1016/j.ajhg.2017.01.026
10.1371/journal.pone.0097311
10.1093/humrep/dem319
10.1016/j.biocel.2011.12.021
10.1038/s41467-017-01261-5
10.1210/en.2006-1692
10.1093/humrep/dev117
10.1016/S1074-7613(04)00046-9
10.1038/nature14248
10.1038/ng.731
10.1038/nrg2538
10.1016/j.fertnstert.2008.12.058
10.1679/aohc.67.393
10.1038/ng1901
10.1210/en.2005-1076
10.1371/journal.pone.0058419
10.1093/humrep/14.5.1328
10.1371/journal.pgen.1005858
10.1371/journal.pgen.1006643
10.1371/journal.pgen.1005908
10.1371/journal.pbio.0050123
10.1101/gr.190603.115
10.1016/j.fertnstert.2017.07.007
10.1093/humrep/dev051
10.1038/nature12873
10.1111/jog.12392
10.1093/humrep/dew047
10.1210/jc.2003-031389
10.1016/S0950-3552(05)80092-6
10.1177/1933719112443877
10.1093/humrep/dex006
10.1038/ng2068
10.1093/humupd/dmv038
10.1186/s13742-015-0047-8
10.1093/molehr/gah121
10.1242/jcs.01726
10.1093/humrep/14.suppl_2.3
10.1038/nature24277
10.1007/s12079-009-0062-6
10.1038/ng.2384
10.2353/ajpath.2008.071128
10.1038/ng.2445
10.1074/jbc.M107811200
10.1016/j.cels.2015.12.004
10.1038/ng.3562
10.1016/j.bbadis.2014.04.024
10.1016/j.fertnstert.2004.10.058
10.1093/humrep/den360
10.1016/j.gene.2012.07.031
10.1530/REP-16-0089
10.1038/ng.3538
10.2337/db07-1305
10.1038/onc.2013.170
10.1007/s00018-011-0781-8
10.1016/0002-9378(79)90302-8
10.1038/ng.3656
10.1534/genetics.111.136549
10.1093/molehr/8.1.75
10.1038/nature05911
10.1111/aji.12679
10.1016/j.scitotenv.2016.07.150
ContentType Journal Article
Copyright The Author(s) 2018
2018. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
Copyright_xml – notice: The Author(s) 2018
– notice: 2018. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
DBID C6C
NPM
AAYXX
CITATION
3V.
7X7
7XB
88A
88E
88I
8FE
8FH
8FI
8FJ
8FK
ABUWG
AFKRA
AZQEC
BBNVY
BENPR
BHPHI
CCPQU
DWQXO
FYUFA
GHDGH
GNUQQ
HCIFZ
K9.
LK8
M0S
M1P
M2P
M7P
PIMPY
PQEST
PQQKQ
PQUKI
Q9U
7X8
5PM
DOI 10.1038/s41598-018-29462-y
DatabaseName SpringerOpen
PubMed
CrossRef
ProQuest Central (Corporate)
Health & Medical Collection (Proquest)
ProQuest Central (purchase pre-March 2016)
Biology Database (Alumni Edition)
Medical Database (Alumni Edition)
Science Database (Alumni Edition)
ProQuest SciTech Collection
ProQuest Natural Science Collection
Hospital Premium Collection
Hospital Premium Collection (Alumni Edition)
ProQuest Central (Alumni) (purchase pre-March 2016)
ProQuest Central (Alumni)
ProQuest Central UK/Ireland
ProQuest Central Essentials
Biological Science Collection
AUTh Library subscriptions: ProQuest Central
ProQuest Natural Science Collection
ProQuest One Community College
ProQuest Central
Health Research Premium Collection
Health Research Premium Collection (Alumni)
ProQuest Central Student
SciTech Premium Collection (Proquest) (PQ_SDU_P3)
ProQuest Health & Medical Complete (Alumni)
Biological Sciences
Health & Medical Collection (Alumni Edition)
PML(ProQuest Medical Library)
ProQuest Science Journals
Biological Science Database
Access via ProQuest (Open Access)
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Academic
ProQuest One Academic UKI Edition
ProQuest Central Basic
MEDLINE - Academic
PubMed Central (Full Participant titles)
DatabaseTitle PubMed
CrossRef
Publicly Available Content Database
ProQuest Central Student
ProQuest Central Essentials
ProQuest Health & Medical Complete (Alumni)
ProQuest Central (Alumni Edition)
SciTech Premium Collection
ProQuest One Community College
ProQuest Natural Science Collection
ProQuest Biology Journals (Alumni Edition)
ProQuest Central
Health Research Premium Collection
Health and Medicine Complete (Alumni Edition)
Natural Science Collection
ProQuest Central Korea
Biological Science Collection
ProQuest Medical Library (Alumni)
ProQuest Science Journals (Alumni Edition)
ProQuest Biological Science Collection
ProQuest Central Basic
ProQuest Science Journals
ProQuest One Academic Eastern Edition
ProQuest Hospital Collection
Health Research Premium Collection (Alumni)
Biological Science Database
ProQuest SciTech Collection
ProQuest Hospital Collection (Alumni)
ProQuest Health & Medical Complete
ProQuest Medical Library
ProQuest One Academic UKI Edition
ProQuest One Academic
ProQuest Central (Alumni)
MEDLINE - Academic
DatabaseTitleList PubMed

Publicly Available Content Database

CrossRef
Database_xml – sequence: 1
  dbid: C6C
  name: SpringerOpen
  url: http://www.springeropen.com/
  sourceTypes: Publisher
– sequence: 2
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 3
  dbid: BENPR
  name: AUTh Library subscriptions: ProQuest Central
  url: https://www.proquest.com/central
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Discipline Biology
EISSN 2045-2322
EndPage 19
ExternalDocumentID 10_1038_s41598_018_29462_y
30061686
Genre Journal Article
GroupedDBID 0R~
3V.
4.4
53G
5VS
7X7
88A
88E
88I
8FE
8FH
8FI
8FJ
AAFWJ
AAJSJ
AAKDD
ABDBF
ABUWG
ACGFS
ACSMW
ADBBV
ADRAZ
AENEX
AFKRA
AJTQC
ALIPV
ALMA_UNASSIGNED_HOLDINGS
AOIJS
AZQEC
BAWUL
BBNVY
BCNDV
BENPR
BHPHI
BPHCQ
BVXVI
C6C
CCPQU
DIK
DWQXO
EBD
EBLON
EBS
EJD
ESX
FYUFA
GNUQQ
GROUPED_DOAJ
GX1
HCIFZ
HH5
HMCUK
HYE
IPNFZ
KQ8
LK8
M0L
M1P
M2P
M48
M7P
M~E
NAO
OK1
PIMPY
PQQKQ
PROAC
PSQYO
RIG
RNT
RNTTT
RPM
SNYQT
UKHRP
NPM
AAYXX
AFPKN
CITATION
7XB
8FK
K9.
PQEST
PQUKI
Q9U
7X8
5PM
ID FETCH-LOGICAL-c577t-6dbc10bc596f4cbb999ef21f1def4059a5fd39c19398075fbc9841c47ccb6e713
IEDL.DBID RPM
ISSN 2045-2322
IngestDate Tue Sep 17 21:28:17 EDT 2024
Fri Oct 25 05:01:31 EDT 2024
Sun Nov 03 00:30:53 EDT 2024
Fri Aug 23 01:03:47 EDT 2024
Wed Oct 16 00:59:45 EDT 2024
Fri Oct 11 20:45:56 EDT 2024
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 1
Language English
License Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c577t-6dbc10bc596f4cbb999ef21f1def4059a5fd39c19398075fbc9841c47ccb6e713
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ORCID 0000-0003-2001-2474
0000-0002-4140-8139
0000-0002-8598-7902
OpenAccessLink https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065421/
PMID 30061686
PQID 2079935494
PQPubID 2041939
PageCount 19
ParticipantIDs pubmedcentral_primary_oai_pubmedcentral_nih_gov_6065421
proquest_miscellaneous_2080840586
proquest_journals_2079935494
crossref_primary_10_1038_s41598_018_29462_y
pubmed_primary_30061686
springer_journals_10_1038_s41598_018_29462_y
PublicationCentury 2000
PublicationDate 2018-07-30
PublicationDateYYYYMMDD 2018-07-30
PublicationDate_xml – month: 07
  year: 2018
  text: 2018-07-30
  day: 30
PublicationDecade 2010
PublicationPlace London
PublicationPlace_xml – name: London
– name: England
PublicationTitle Scientific reports
PublicationTitleAbbrev Sci Rep
PublicationTitleAlternate Sci Rep
PublicationYear 2018
Publisher Nature Publishing Group UK
Nature Publishing Group
Publisher_xml – name: Nature Publishing Group UK
– name: Nature Publishing Group
References Agostini (CR64) 2004; 20
Fung (CR35) 2017; 32
Taylor, Bagot, Kardana, Olive, Arici (CR32) 1999; 14
Meola (CR28) 2010; 93
Cui (CR39) 2014; 33
Lindqvist, van Zon, Karlsson Rosenthal, Wolthuis (CR61) 2007; 5
Kasela (CR67) 2017; 13
Holdsworth-Carson (CR20) 2016; 31
Okada (CR57) 2014; 40
Punyadeera (CR43) 2005; 62
Lloyd-Jones (CR77) 2017; 100
Cheng (CR36) 2016; 48
Peters (CR8) 2016; 12
Westra, Franke (CR9) 2014; 1842
Consortium (CR12) 2017; 550
Yusuf (CR29) 2014; 134
Burrows (CR52) 2016; 12
Díaz-Gimeno (CR59) 2017; 108
Matsuzaki (CR47) 1999; 5
Burney (CR7) 2007; 148
Rivera, Bradshaw, Brekken (CR26) 2011; 68
Steffen (CR40) 2012; 191
Lucidi (CR16) 2005; 84
Liberzon (CR24) 2015; 1
Turkyilmaz (CR62) 2012; 508
Williams, Chan, Cowley, Little (CR10) 2007; 17
Das (CR74) 2016; 48
Ponnampalam, Weston, Trajstman, Susil, Rogers (CR1) 2004; 10
Giudice (CR5) 1999; 14
Dunn, Critchley, Kelly (CR56) 2002; 87
Haouzi (CR44) 2009; 24
Chang (CR73) 2015; 4
Talbi (CR2) 2006; 147
Bhagwat (CR41) 2013; 8
Bradshaw (CR27) 2009; 3
Painter (CR22) 2011; 43
Shi (CR38) 2012; 44
Altmae (CR53) 2017; 7
Nyholt (CR18) 2012; 44
Tapia (CR54) 2008; 23
Daftary, Taylor (CR33) 2004; 89
Maybin, Critchley (CR6) 2015; 21
Watanabe, Taskesen, van Bochoven, Posthuma (CR75) 2017; 8
Bradshaw (CR25) 2012; 44
Jin (CR71) 2012; 44
Razmara (CR65) 2002; 277
Powell (CR21) 2016; 25
(CR13) 2015; 348
Chen (CR30) 2015; 2015
CR55
Vallejo (CR60) 2014; 9
Yu (CR58) 2016; 152
Todd (CR70) 2007; 39
Fung (CR19) 2015; 30
Zhu (CR34) 2016; 48
Petracco, Kong, Grechukhina, Krikun, Taylor (CR42) 2012; 19
Hakonarson (CR69) 2008; 57
Roadmap Epigenomics (CR14) 2015; 518
Carroll (CR49) 2006; 38
Okada (CR72) 2014; 506
Sapkota (CR23) 2017; 8
Harper (CR4) 1992; 6
Lowe, Reddy (CR11) 2015; 25
Shi, Gu, Chen, Guo, Shi (CR31) 2014; 33
Slayden, Brenner (CR46) 2004; 67
Pole (CR48) 2005; 206
Fung (CR3) 2017; 32
CR68
Ferenczy, Bertrand, Gelfand (CR45) 1979; 133
Sommerville, Brumwell, Politz, Pederson (CR37) 2005; 118
Hull (CR17) 2008; 173
Liao (CR51) 2015; 30
CR63
Vaquerizas, Kummerfeld, Teichmann, Luscombe (CR76) 2009; 10
Enchev, Schulman, Peter (CR50) 2014; 16
Giudice (CR15) 2010; 362
Khorram, Garthwaite, Golos (CR66) 2002; 8
22249026 - Int J Biochem Cell Biol. 2012 Mar;44(3):480-8
24769035 - Gynecol Oncol. 2014 Aug;134(2):356-63
24390342 - Nature. 2014 Feb 20;506(7488):376-81
15030775 - Immunity. 2004 Mar;20(3):319-25
27015630 - PLoS Genet. 2016 Mar 25;12(3):e1005908
22885925 - Nat Genet. 2012 Sep;44(9):1020-5
17510236 - Endocrinology. 2007 Aug;148(8):3814-26
16306079 - Endocrinology. 2006 Mar;147(3):1097-121
25788566 - Hum Reprod. 2015 May;30(5):1263-75
15781981 - Arch Histol Cytol. 2004 Dec;67(5):393-409
15741230 - J Cell Sci. 2005 Mar 15;118(Pt 6):1299-307
10341004 - Mol Hum Reprod. 1999 Jun;5(6):559-64
17554260 - Nat Genet. 2007 Jul;39(7):857-64
22561518 - Nat Genet. 2012 May 06;44(6):676-80
22885067 - Gene. 2012 Oct 15;508(1):140-3
26771021 - Cell Syst. 2015 Dec 23;1(6):417-425
11756572 - Mol Hum Reprod. 2002 Jan;8(1):75-80
28863933 - Fertil Steril. 2017 Oct;108(4):703-710.e3
17472438 - PLoS Biol. 2007 May;5(5):e123
23728348 - Oncogene. 2014 Apr 24;33(17):2225-35
28370781 - Am J Reprod Immunol. 2017 Jul;78(1)
18077318 - Hum Reprod. 2008 Feb;23(2):340-51
27005890 - Hum Reprod. 2016 May;31(5):999-1013
21822645 - Cell Mol Life Sci. 2011 Oct;68(19):3165-73
15666095 - Cell Mol Life Sci. 2005 Jan;62(2):239-50
29022597 - Nature. 2017 Oct 11;550(7675):204-213
27476725 - Sci Total Environ. 2016 Nov 15;571:1222-9
15501903 - Mol Hum Reprod. 2004 Dec;10(12):879-93
22377630 - Genetics. 2012 May;191(1):107-18
1424330 - Baillieres Clin Obstet Gynaecol. 1992 Jun;6(2):351-71
19798598 - J Cell Commun Signal. 2009 Dec;3(3-4):239-46
11932337 - J Clin Endocrinol Metab. 2002 Apr;87(4):1898-901
23104006 - Nat Genet. 2012 Dec;44(12):1355-9
23555582 - PLoS One. 2013;8(3):e58419
18688027 - Am J Pathol. 2008 Sep;173(3):700-15
17554300 - Nature. 2007 Jun 7;447(7145):661-78
17013392 - Nat Genet. 2006 Nov;38(11):1289-97
28855728 - Sci Rep. 2017 Aug 30;7(1):10077
28248954 - PLoS Genet. 2017 Mar 1;13(3):e1006643
10690796 - Hum Reprod. 1999 Dec;14 Suppl 2:3-16
24173391 - Int J Mol Med. 2014 Jan;33(1):59-67
18835874 - Hum Reprod. 2009 Jan;24(1):198-205
26430153 - Genome Res. 2015 Oct;25(10):1432-41
25693563 - Nature. 2015 Feb 19;518(7539):317-30
27190213 - Reproduction. 2016 Aug;152(2):151-60
15126568 - J Clin Endocrinol Metab. 2004 May;89(5):2390-6
28171565 - Hum Mol Genet. 2016 Nov 15;25(22):5046-5058
28537267 - Nat Commun. 2017 May 24;8:15539
25722852 - Gigascience. 2015 Feb 25;4:7
24754847 - J Obstet Gynaecol Res. 2014 May;40(5):1180-7
26003431 - Hum Reprod. 2015 Jul;30(7):1665-76
20573927 - N Engl J Med. 2010 Jun 24;362(25):2389-98
28157541 - Am J Hum Genet. 2017 Feb 2;100(2):371
18198356 - Diabetes. 2008 Apr;57(4):1143-6
10325287 - Hum Reprod. 1999 May;14(5):1328-31
15590111 - Toxicology. 2005 Jan 5;206(1):91-109
27571263 - Nat Genet. 2016 Oct;48(10):1284-1287
16009148 - Fertil Steril. 2005 Jul;84(1):16-21
22623515 - Reprod Sci. 2012 Oct;19(10):1138-45
19274049 - Nat Rev Genet. 2009 Apr;10(4):252-63
21151130 - Nat Genet. 2011 Jan;43(1):51-4
26253932 - Hum Reprod Update. 2015 Nov-Dec;21(6):748-61
24859236 - PLoS One. 2014 May 23;9(5):e97311
19200988 - Fertil Steril. 2010 Apr;93(6):1750-73
11821383 - J Biol Chem. 2002 Apr 19;277(16):13952-8
18063559 - Genome Res. 2007 Dec;17(12):1707-16
434029 - Am J Obstet Gynecol. 1979 Apr 15;133(8):859-67
24798236 - Biochim Biophys Acta. 2014 Oct;1842(10):1896-1902
27447835 - PLoS Genet. 2016 Jul 22;12(7):e1005858
25954001 - Science. 2015 May 8;348(6235):648-60
25531226 - Nat Rev Mol Cell Biol. 2015 Jan;16(1):30-44
29184056 - Nat Commun. 2017 Nov 28;8(1):1826
27135401 - Nat Genet. 2016 Jun;48(6):667-674
26357653 - Biomed Res Int. 2015;2015:340218
27019110 - Nat Genet. 2016 May;48(5):481-7
28177073 - Hum Reprod. 2017 Apr 1;32(4):893-904
LC Giudice (29462_CR5) 1999; 14
S Talbi (29462_CR2) 2006; 147
XY Shi (29462_CR31) 2014; 33
Y Sapkota (29462_CR23) 2017; 8
S Matsuzaki (29462_CR47) 1999; 5
29462_CR55
RI Enchev (29462_CR50) 2014; 16
JN Painter (29462_CR22) 2011; 43
GT Consortium (29462_CR12) 2017; 550
GTExConsortium. Human genomics (29462_CR13) 2015; 348
LC Giudice (29462_CR15) 2010; 362
S Kasela (29462_CR67) 2017; 13
AD Bradshaw (29462_CR27) 2009; 3
C Punyadeera (29462_CR43) 2005; 62
JA Todd (29462_CR70) 2007; 39
JS Carroll (29462_CR49) 2006; 38
J Chen (29462_CR30) 2015; 2015
SR Bhagwat (29462_CR41) 2013; 8
A Lindqvist (29462_CR61) 2007; 5
O Khorram (29462_CR66) 2002; 8
Y Jin (29462_CR71) 2012; 44
DR Nyholt (29462_CR18) 2012; 44
JN Fung (29462_CR3) 2017; 32
RS Lucidi (29462_CR16) 2005; 84
WL Lowe Jr. (29462_CR11) 2015; 25
D Cui (29462_CR39) 2014; 33
M Razmara (29462_CR65) 2002; 277
29462_CR68
D Haouzi (29462_CR44) 2009; 24
LB Rivera (29462_CR26) 2011; 68
HS Taylor (29462_CR32) 1999; 14
29462_CR63
A Tapia (29462_CR54) 2008; 23
CK Burrows (29462_CR52) 2016; 12
E Turkyilmaz (29462_CR62) 2012; 508
Z Zhu (29462_CR34) 2016; 48
CC Chang (29462_CR73) 2015; 4
AD Bradshaw (29462_CR25) 2012; 44
C Roadmap Epigenomics (29462_CR14) 2015; 518
JE Peters (29462_CR8) 2016; 12
JA Maybin (29462_CR6) 2015; 21
H Okada (29462_CR57) 2014; 40
N Yusuf (29462_CR29) 2014; 134
JN Fung (29462_CR35) 2017; 32
RO Burney (29462_CR7) 2007; 148
GS Daftary (29462_CR33) 2004; 89
Y Shi (29462_CR38) 2012; 44
JE Powell (29462_CR21) 2016; 25
SJ Holdsworth-Carson (29462_CR20) 2016; 31
J Meola (29462_CR28) 2010; 93
AP Ponnampalam (29462_CR1) 2004; 10
J-J Yu (29462_CR58) 2016; 152
HJ Westra (29462_CR9) 2014; 1842
S Das (29462_CR74) 2016; 48
A Liberzon (29462_CR24) 2015; 1
M Pole (29462_CR48) 2005; 206
CL Dunn (29462_CR56) 2002; 87
J Sommerville (29462_CR37) 2005; 118
L Agostini (29462_CR64) 2004; 20
H Hakonarson (29462_CR69) 2008; 57
LR Lloyd-Jones (29462_CR77) 2017; 100
S Altmae (29462_CR53) 2017; 7
Y Liao (29462_CR51) 2015; 30
OD Slayden (29462_CR46) 2004; 67
TH Cheng (29462_CR36) 2016; 48
JN Fung (29462_CR19) 2015; 30
ML Hull (29462_CR17) 2008; 173
Y Okada (29462_CR72) 2014; 506
P Díaz-Gimeno (29462_CR59) 2017; 108
JM Vaquerizas (29462_CR76) 2009; 10
KK Steffen (29462_CR40) 2012; 191
G Vallejo (29462_CR60) 2014; 9
RG Petracco (29462_CR42) 2012; 19
MJ Harper (29462_CR4) 1992; 6
A Ferenczy (29462_CR45) 1979; 133
K Watanabe (29462_CR75) 2017; 8
RB Williams (29462_CR10) 2007; 17
References_xml – volume: 348
  start-page: 648
  year: 2015
  end-page: 60
  ident: CR13
  article-title: The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans
  publication-title: Science
  doi: 10.1126/science.1262110
– volume: 44
  start-page: 676
  year: 2012
  end-page: 680
  ident: CR71
  article-title: Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo
  publication-title: Nat Genet
  doi: 10.1038/ng.2272
  contributor:
    fullname: Jin
– ident: CR68
– volume: 33
  start-page: 59
  year: 2014
  end-page: 67
  ident: CR31
  article-title: Downregulation of miR-183 inhibits apoptosis and enhances the invasive potential of endometrial stromal cells in endometriosis
  publication-title: Int J Mol Med
  doi: 10.3892/ijmm.2013.1536
  contributor:
    fullname: Shi
– volume: 7
  year: 2017
  ident: CR53
  article-title: Meta-signature of human endometrial receptivity: a meta-analysis and validation study of transcriptomic biomarkers
  publication-title: Sci Rep
  doi: 10.1038/s41598-017-10098-3
  contributor:
    fullname: Altmae
– volume: 87
  start-page: 1898
  year: 2002
  end-page: 1901
  ident: CR56
  article-title: IL-15 Regulation in Human Endometrial Stromal Cells
  publication-title: The Journal of Clinical Endocrinology & Metabolism
  doi: 10.1210/jcem.87.4.8539
  contributor:
    fullname: Kelly
– volume: 17
  start-page: 1707
  year: 2007
  end-page: 16
  ident: CR10
  article-title: The influence of genetic variation on gene expression
  publication-title: Genome Res
  doi: 10.1101/gr.6981507
  contributor:
    fullname: Little
– volume: 134
  start-page: 356
  year: 2014
  end-page: 63
  ident: CR29
  article-title: SPARC was overexpressed in human endometrial cancer stem-like cells and promoted migration activity
  publication-title: Gynecol Oncol
  doi: 10.1016/j.ygyno.2014.04.009
  contributor:
    fullname: Yusuf
– volume: 362
  start-page: 2389
  year: 2010
  end-page: 98
  ident: CR15
  article-title: Clinical practice. Endometriosis
  publication-title: N Engl J Med
  doi: 10.1056/NEJMcp1000274
  contributor:
    fullname: Giudice
– volume: 206
  start-page: 91
  year: 2005
  end-page: 109
  ident: CR48
  article-title: Gene expression changes induced by estrogen and selective estrogen receptor modulators in primary-cultured human endometrial cells: signals that distinguish the human carcinogen tamoxifen
  publication-title: Toxicology
  doi: 10.1016/j.tox.2004.07.005
  contributor:
    fullname: Pole
– volume: 8
  year: 2017
  ident: CR23
  article-title: Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism
  publication-title: Nat Commun
  doi: 10.1038/ncomms15539
  contributor:
    fullname: Sapkota
– volume: 62
  start-page: 239
  year: 2005
  end-page: 250
  ident: CR43
  article-title: Oestrogen-modulated gene expression in the human endometrium
  publication-title: Cellular and Molecular Life Sciences CMLS
  doi: 10.1007/s00018-004-4435-y
  contributor:
    fullname: Punyadeera
– volume: 100
  start-page: 371
  year: 2017
  ident: CR77
  article-title: The Genetic Architecture of Gene Expression in Peripheral Blood
  publication-title: Am J Hum Genet
  doi: 10.1016/j.ajhg.2017.01.026
  contributor:
    fullname: Lloyd-Jones
– volume: 9
  start-page: e97311
  year: 2014
  ident: CR60
  article-title: CDC2 Mediates Progestin Initiated Endometrial Stromal Cell Proliferation: A PR Signaling to Gene Expression Independently of Its Binding to Chromatin
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0097311
  contributor:
    fullname: Vallejo
– volume: 23
  start-page: 340
  year: 2008
  end-page: 51
  ident: CR54
  article-title: Differences in the endometrial transcript profile during the receptive period between women who were refractory to implantation and those who achieved pregnancy
  publication-title: Hum Reprod
  doi: 10.1093/humrep/dem319
  contributor:
    fullname: Tapia
– volume: 25
  start-page: 5046
  year: 2016
  end-page: 5058
  ident: CR21
  article-title: Endometriosis risk alleles at 1p36.12 act through inverse regulation of CDC42 and LINC00339
  publication-title: Hum Mol Genet
  contributor:
    fullname: Powell
– volume: 16
  start-page: 30
  year: 2014
  ident: CR50
  publication-title: Protein neddylation: beyond cullin–RING ligases.
  contributor:
    fullname: Peter
– volume: 44
  start-page: 480
  year: 2012
  end-page: 8
  ident: CR25
  article-title: Diverse biological functions of the SPARC family of proteins
  publication-title: Int J Biochem Cell Biol
  doi: 10.1016/j.biocel.2011.12.021
  contributor:
    fullname: Bradshaw
– volume: 8
  year: 2017
  ident: CR75
  article-title: Functional mapping and annotation of genetic associations with FUMA
  publication-title: Nat Commun
  doi: 10.1038/s41467-017-01261-5
  contributor:
    fullname: Posthuma
– volume: 148
  start-page: 3814
  year: 2007
  end-page: 26
  ident: CR7
  article-title: Gene expression analysis of endometrium reveals progesterone resistance and candidate susceptibility genes in women with endometriosis
  publication-title: Endocrinology
  doi: 10.1210/en.2006-1692
  contributor:
    fullname: Burney
– volume: 30
  start-page: 1665
  year: 2015
  end-page: 1676
  ident: CR51
  article-title: NEDD8-mediated neddylation is required for human endometrial stromal proliferation and decidualization
  publication-title: Human Reproduction
  doi: 10.1093/humrep/dev117
  contributor:
    fullname: Liao
– volume: 20
  start-page: 319
  year: 2004
  end-page: 25
  ident: CR64
  article-title: NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
  publication-title: Immunity
  doi: 10.1016/S1074-7613(04)00046-9
  contributor:
    fullname: Agostini
– volume: 518
  start-page: 317
  year: 2015
  end-page: 30
  ident: CR14
  article-title: Integrative analysis of 111 reference human epigenomes
  publication-title: Nature
  doi: 10.1038/nature14248
  contributor:
    fullname: Roadmap Epigenomics
– volume: 43
  start-page: 51
  year: 2011
  end-page: 4
  ident: CR22
  article-title: Genome-wide association study identifies a locus at 7p15.2 associated with endometriosis
  publication-title: Nat Genet
  doi: 10.1038/ng.731
  contributor:
    fullname: Painter
– volume: 10
  start-page: 252
  year: 2009
  end-page: 63
  ident: CR76
  article-title: A census of human transcription factors: function, expression and evolution
  publication-title: Nat Rev Genet
  doi: 10.1038/nrg2538
  contributor:
    fullname: Luscombe
– volume: 93
  start-page: 1750
  year: 2010
  end-page: 73
  ident: CR28
  article-title: Differentially expressed genes in eutopic and ectopic endometrium of women with endometriosis
  publication-title: Fertil Steril
  doi: 10.1016/j.fertnstert.2008.12.058
  contributor:
    fullname: Meola
– volume: 67
  start-page: 393
  year: 2004
  end-page: 409
  ident: CR46
  article-title: Hormonal regulation and localization of estrogen, progestin and androgen receptors in the endometrium of nonhuman primates: effects of progesterone receptor antagonists
  publication-title: Archives of Histology and Cytology
  doi: 10.1679/aohc.67.393
  contributor:
    fullname: Brenner
– volume: 38
  start-page: 1289
  year: 2006
  end-page: 1297
  ident: CR49
  article-title: Genome-wide analysis of estrogen receptor binding sites
  publication-title: Nat Genet
  doi: 10.1038/ng1901
  contributor:
    fullname: Carroll
– volume: 147
  start-page: 1097
  year: 2006
  end-page: 121
  ident: CR2
  article-title: Molecular phenotyping of human endometrium distinguishes menstrual cycle phases and underlying biological processes in normo-ovulatory women
  publication-title: Endocrinology
  doi: 10.1210/en.2005-1076
  contributor:
    fullname: Talbi
– volume: 8
  start-page: e58419
  year: 2013
  ident: CR41
  article-title: Endometrial receptivity: a revisit to functional genomics studies on human endometrium and creation of HGEx-ERdb
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0058419
  contributor:
    fullname: Bhagwat
– volume: 14
  start-page: 1328
  year: 1999
  end-page: 31
  ident: CR32
  article-title: HOX gene expression is altered in the endometrium of women with endometriosis
  publication-title: Hum Reprod
  doi: 10.1093/humrep/14.5.1328
  contributor:
    fullname: Arici
– volume: 12
  start-page: e1005858
  year: 2016
  ident: CR52
  article-title: Expression Quantitative Trait Locus Mapping Studies in Mid-secretory Phase Endometrial Cells Identifies HLA-F and TAP2 as Fecundability-Associated Genes
  publication-title: PLOS Genetics
  doi: 10.1371/journal.pgen.1005858
  contributor:
    fullname: Burrows
– volume: 13
  start-page: e1006643
  year: 2017
  ident: CR67
  article-title: Pathogenic implications for autoimmune mechanisms derived by comparative eQTL analysis of CD4+ versus CD8+ T cells
  publication-title: PLOS Genetics
  doi: 10.1371/journal.pgen.1006643
  contributor:
    fullname: Kasela
– volume: 12
  start-page: e1005908
  year: 2016
  ident: CR8
  article-title: Insight into Genotype-Phenotype Associations through eQTL Mapping in Multiple Cell Types in Health and Immune-Mediated Disease
  publication-title: PLoS Genet
  doi: 10.1371/journal.pgen.1005908
  contributor:
    fullname: Peters
– volume: 5
  start-page: e123
  year: 2007
  ident: CR61
  article-title: Cyclin B1–Cdk1 Activation Continues after Centrosome Separation to Control Mitotic Progression
  publication-title: PLoS Biology
  doi: 10.1371/journal.pbio.0050123
  contributor:
    fullname: Wolthuis
– volume: 25
  start-page: 1432
  year: 2015
  end-page: 41
  ident: CR11
  article-title: Genomic approaches for understanding the genetics of complex disease
  publication-title: Genome Res
  doi: 10.1101/gr.190603.115
  contributor:
    fullname: Reddy
– volume: 108
  start-page: 703
  year: 2017
  end-page: 710.e3
  ident: CR59
  article-title: Window of implantation transcriptomic stratification reveals different endometrial subsignatures associated with live birth and biochemical pregnancy
  publication-title: Fertility and Sterility
  doi: 10.1016/j.fertnstert.2017.07.007
  contributor:
    fullname: Díaz-Gimeno
– volume: 30
  start-page: 1263
  year: 2015
  end-page: 75
  ident: CR19
  article-title: Functional evaluation of genetic variants associated with endometriosis near GREB1
  publication-title: Hum Reprod
  doi: 10.1093/humrep/dev051
  contributor:
    fullname: Fung
– volume: 506
  start-page: 376
  year: 2014
  end-page: 381
  ident: CR72
  article-title: Genetics of rheumatoid arthritis contributes to biology and drug discovery
  publication-title: Nature
  doi: 10.1038/nature12873
  contributor:
    fullname: Okada
– volume: 40
  start-page: 1180
  year: 2014
  end-page: 1187
  ident: CR57
  article-title: Regulation of decidualization and angiogenesis in the human endometrium: Mini review
  publication-title: Journal of Obstetrics and Gynaecology Research
  doi: 10.1111/jog.12392
  contributor:
    fullname: Okada
– volume: 31
  start-page: 999
  year: 2016
  end-page: 1013
  ident: CR20
  article-title: Endometrial vezatin and its association with endometriosis risk
  publication-title: Hum Reprod
  doi: 10.1093/humrep/dew047
  contributor:
    fullname: Holdsworth-Carson
– volume: 89
  start-page: 2390
  year: 2004
  end-page: 6
  ident: CR33
  article-title: EMX2 gene expression in the female reproductive tract and aberrant expression in the endometrium of patients with endometriosis
  publication-title: J Clin Endocrinol Metab
  doi: 10.1210/jc.2003-031389
  contributor:
    fullname: Taylor
– volume: 6
  start-page: 351
  year: 1992
  end-page: 71
  ident: CR4
  article-title: The implantation window
  publication-title: Baillieres Clin Obstet Gynaecol
  doi: 10.1016/S0950-3552(05)80092-6
  contributor:
    fullname: Harper
– volume: 19
  start-page: 1138
  year: 2012
  end-page: 45
  ident: CR42
  article-title: Global gene expression profiling of proliferative phase endometrium reveals distinct functional subdivisions
  publication-title: Reprod Sci
  doi: 10.1177/1933719112443877
  contributor:
    fullname: Taylor
– volume: 32
  start-page: 1
  year: 2017
  end-page: 12
  ident: CR3
  article-title: The genetic regulation of transcription in human endometrial tissue
  publication-title: Hum Reprod
  doi: 10.1093/humrep/dex006
  contributor:
    fullname: Fung
– volume: 39
  start-page: 857
  year: 2007
  end-page: 864
  ident: CR70
  article-title: Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes
  publication-title: Nat Genet
  doi: 10.1038/ng2068
  contributor:
    fullname: Todd
– volume: 21
  start-page: 748
  year: 2015
  end-page: 61
  ident: CR6
  article-title: Menstrual physiology: implications for endometrial pathology and beyond
  publication-title: Hum Reprod Update
  doi: 10.1093/humupd/dmv038
  contributor:
    fullname: Critchley
– volume: 4
  year: 2015
  ident: CR73
  article-title: Second-generation PLINK: rising to the challenge of larger and richer datasets
  publication-title: Gigascience
  doi: 10.1186/s13742-015-0047-8
  contributor:
    fullname: Chang
– volume: 10
  start-page: 879
  year: 2004
  end-page: 93
  ident: CR1
  article-title: Molecular classification of human endometrial cycle stages by transcriptional profiling
  publication-title: Mol Hum Reprod
  doi: 10.1093/molehr/gah121
  contributor:
    fullname: Rogers
– volume: 2015
  start-page: 340218
  year: 2015
  ident: CR30
  article-title: MiR-183 Regulates ITGB1P Expression and Promotes Invasion of Endometrial Stromal Cells
  publication-title: Biomed Res Int
  contributor:
    fullname: Chen
– volume: 118
  start-page: 1299
  year: 2005
  end-page: 307
  ident: CR37
  article-title: Signal recognition particle assembly in relation to the function of amplified nucleoli of Xenopus oocytes
  publication-title: J Cell Sci
  doi: 10.1242/jcs.01726
  contributor:
    fullname: Pederson
– ident: CR63
– volume: 14
  start-page: 3
  issue: Suppl 2
  year: 1999
  end-page: 16
  ident: CR5
  article-title: Potential biochemical markers of uterine receptivity
  publication-title: Hum Reprod
  doi: 10.1093/humrep/14.suppl_2.3
  contributor:
    fullname: Giudice
– volume: 550
  start-page: 204
  year: 2017
  end-page: 213
  ident: CR12
  article-title: Genetic effects on gene expression across human tissues
  publication-title: Nature
  doi: 10.1038/nature24277
  contributor:
    fullname: Consortium
– volume: 3
  start-page: 239
  year: 2009
  end-page: 46
  ident: CR27
  article-title: The role of SPARC in extracellular matrix assembly
  publication-title: J Cell Commun Signal
  doi: 10.1007/s12079-009-0062-6
  contributor:
    fullname: Bradshaw
– volume: 44
  start-page: 1020
  year: 2012
  end-page: 5
  ident: CR38
  article-title: Genome-wide association study identifies eight new risk loci for polycystic ovary syndrome
  publication-title: Nat Genet
  doi: 10.1038/ng.2384
  contributor:
    fullname: Shi
– volume: 173
  start-page: 700
  year: 2008
  end-page: 15
  ident: CR17
  article-title: Endometrial-peritoneal interactions during endometriotic lesion establishment
  publication-title: Am J Pathol
  doi: 10.2353/ajpath.2008.071128
  contributor:
    fullname: Hull
– volume: 44
  start-page: 1355
  year: 2012
  end-page: 9
  ident: CR18
  article-title: Genome-wide association meta-analysis identifies new endometriosis risk loci
  publication-title: Nat Genet
  doi: 10.1038/ng.2445
  contributor:
    fullname: Nyholt
– volume: 277
  start-page: 13952
  year: 2002
  end-page: 8
  ident: CR65
  article-title: CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M107811200
  contributor:
    fullname: Razmara
– volume: 1
  start-page: 417
  year: 2015
  end-page: 425
  ident: CR24
  article-title: The Molecular Signatures Database (MSigDB) hallmark gene set collection
  publication-title: Cell Syst
  doi: 10.1016/j.cels.2015.12.004
  contributor:
    fullname: Liberzon
– volume: 48
  start-page: 667
  year: 2016
  end-page: 674
  ident: CR36
  article-title: Five endometrial cancer risk loci identified through genome-wide association analysis
  publication-title: Nat Genet
  doi: 10.1038/ng.3562
  contributor:
    fullname: Cheng
– volume: 1842
  start-page: 1896
  year: 2014
  end-page: 1902
  ident: CR9
  article-title: From genome to function by studying eQTLs
  publication-title: Biochim Biophys Acta
  doi: 10.1016/j.bbadis.2014.04.024
  contributor:
    fullname: Franke
– volume: 84
  start-page: 16
  year: 2005
  end-page: 21
  ident: CR16
  article-title: A novel model of the early endometriotic lesion demonstrates that attachment of endometrial cells to mesothelial cells is dependent on the source of endometrial cells
  publication-title: Fertil Steril
  doi: 10.1016/j.fertnstert.2004.10.058
  contributor:
    fullname: Lucidi
– volume: 24
  start-page: 198
  year: 2009
  end-page: 205
  ident: CR44
  article-title: Identification of new biomarkers of human endometrial receptivity in the natural cycle
  publication-title: Human Reproduction
  doi: 10.1093/humrep/den360
  contributor:
    fullname: Haouzi
– volume: 508
  start-page: 140
  year: 2012
  end-page: 143
  ident: CR62
  article-title: NLF2 gene expression in the endometrium of patients with implantation failure after IVF treatment
  publication-title: Gene
  doi: 10.1016/j.gene.2012.07.031
  contributor:
    fullname: Turkyilmaz
– volume: 152
  start-page: 151
  year: 2016
  end-page: 160
  ident: CR58
  article-title: IL15 promotes growth and invasion of endometrial stromal cells and inhibits killing activity of NK cells in endometriosis
  publication-title: Reproduction
  doi: 10.1530/REP-16-0089
  contributor:
    fullname: Yu
– volume: 32
  start-page: 893
  year: 2017
  end-page: 904
  ident: CR35
  article-title: The genetic regulation of transcription in human endometrial tissue
  publication-title: Human Reproduction
  doi: 10.1093/humrep/dex006
  contributor:
    fullname: Fung
– ident: CR55
– volume: 48
  start-page: 481
  year: 2016
  end-page: 487
  ident: CR34
  article-title: Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets
  publication-title: Nat Genet
  doi: 10.1038/ng.3538
  contributor:
    fullname: Zhu
– volume: 57
  start-page: 1143
  year: 2008
  ident: CR69
  article-title: A Novel Susceptibility Locus for Type 1 Diabetes on Chr12q13 Identified by a Genome-Wide Association Study
  publication-title: Diabetes
  doi: 10.2337/db07-1305
  contributor:
    fullname: Hakonarson
– volume: 33
  start-page: 2225
  year: 2014
  end-page: 35
  ident: CR39
  article-title: The ribosomal protein S26 regulates p53 activity in response to DNA damage
  publication-title: Oncogene
  doi: 10.1038/onc.2013.170
  contributor:
    fullname: Cui
– volume: 5
  start-page: 559
  year: 1999
  end-page: 564
  ident: CR47
  article-title: Oestrogen receptor α and β mRNA expression in human endometrium throughout the menstrual cycle
  publication-title: MHR: Basic science of reproductive medicine
  contributor:
    fullname: Matsuzaki
– volume: 68
  start-page: 3165
  year: 2011
  end-page: 73
  ident: CR26
  article-title: The regulatory function of SPARC in vascular biology
  publication-title: Cell Mol Life Sci
  doi: 10.1007/s00018-011-0781-8
  contributor:
    fullname: Brekken
– volume: 133
  start-page: 859
  year: 1979
  end-page: 867
  ident: CR45
  article-title: Proliferation kinetics of human endometrium during the normal menstrual cycle
  publication-title: American Journal of Obstetrics and Gynecology
  doi: 10.1016/0002-9378(79)90302-8
  contributor:
    fullname: Gelfand
– volume: 48
  start-page: 1284
  year: 2016
  end-page: 1287
  ident: CR74
  article-title: Next-generation genotype imputation service and methods
  publication-title: Nat Genet
  doi: 10.1038/ng.3656
  contributor:
    fullname: Das
– volume: 191
  start-page: 107
  year: 2012
  end-page: 18
  ident: CR40
  article-title: Ribosome deficiency protects against ER stress in Saccharomyces cerevisiae
  publication-title: Genetics
  doi: 10.1534/genetics.111.136549
  contributor:
    fullname: Steffen
– volume: 8
  start-page: 75
  year: 2002
  end-page: 80
  ident: CR66
  article-title: Uterine and ovarian aryl hydrocarbon receptor (AHR) and aryl hydrocarbon receptor nuclear translocator (ARNT) mRNA expression in benign and malignant gynaecological conditions
  publication-title: Mol Hum Reprod
  doi: 10.1093/molehr/8.1.75
  contributor:
    fullname: Golos
– volume: 21
  start-page: 748
  year: 2015
  ident: 29462_CR6
  publication-title: Hum Reprod Update
  doi: 10.1093/humupd/dmv038
  contributor:
    fullname: JA Maybin
– volume: 84
  start-page: 16
  year: 2005
  ident: 29462_CR16
  publication-title: Fertil Steril
  doi: 10.1016/j.fertnstert.2004.10.058
  contributor:
    fullname: RS Lucidi
– volume: 134
  start-page: 356
  year: 2014
  ident: 29462_CR29
  publication-title: Gynecol Oncol
  doi: 10.1016/j.ygyno.2014.04.009
  contributor:
    fullname: N Yusuf
– volume: 48
  start-page: 481
  year: 2016
  ident: 29462_CR34
  publication-title: Nat Genet
  doi: 10.1038/ng.3538
  contributor:
    fullname: Z Zhu
– volume: 48
  start-page: 1284
  year: 2016
  ident: 29462_CR74
  publication-title: Nat Genet
  doi: 10.1038/ng.3656
  contributor:
    fullname: S Das
– volume: 23
  start-page: 340
  year: 2008
  ident: 29462_CR54
  publication-title: Hum Reprod
  doi: 10.1093/humrep/dem319
  contributor:
    fullname: A Tapia
– volume: 152
  start-page: 151
  year: 2016
  ident: 29462_CR58
  publication-title: Reproduction
  doi: 10.1530/REP-16-0089
  contributor:
    fullname: J-J Yu
– volume: 44
  start-page: 1355
  year: 2012
  ident: 29462_CR18
  publication-title: Nat Genet
  doi: 10.1038/ng.2445
  contributor:
    fullname: DR Nyholt
– ident: 29462_CR68
  doi: 10.1038/nature05911
– volume: 32
  start-page: 1
  year: 2017
  ident: 29462_CR3
  publication-title: Hum Reprod
  doi: 10.1093/humrep/dex006
  contributor:
    fullname: JN Fung
– volume: 16
  start-page: 30
  year: 2014
  ident: 29462_CR50
  publication-title: Protein neddylation: beyond cullin–RING ligases.
  contributor:
    fullname: RI Enchev
– volume: 44
  start-page: 676
  year: 2012
  ident: 29462_CR71
  publication-title: Nat Genet
  doi: 10.1038/ng.2272
  contributor:
    fullname: Y Jin
– volume: 38
  start-page: 1289
  year: 2006
  ident: 29462_CR49
  publication-title: Nat Genet
  doi: 10.1038/ng1901
  contributor:
    fullname: JS Carroll
– ident: 29462_CR55
  doi: 10.1111/aji.12679
– volume: 87
  start-page: 1898
  year: 2002
  ident: 29462_CR56
  publication-title: The Journal of Clinical Endocrinology & Metabolism
  doi: 10.1210/jcem.87.4.8539
  contributor:
    fullname: CL Dunn
– volume: 277
  start-page: 13952
  year: 2002
  ident: 29462_CR65
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M107811200
  contributor:
    fullname: M Razmara
– volume: 147
  start-page: 1097
  year: 2006
  ident: 29462_CR2
  publication-title: Endocrinology
  doi: 10.1210/en.2005-1076
  contributor:
    fullname: S Talbi
– volume: 148
  start-page: 3814
  year: 2007
  ident: 29462_CR7
  publication-title: Endocrinology
  doi: 10.1210/en.2006-1692
  contributor:
    fullname: RO Burney
– volume: 39
  start-page: 857
  year: 2007
  ident: 29462_CR70
  publication-title: Nat Genet
  doi: 10.1038/ng2068
  contributor:
    fullname: JA Todd
– volume: 100
  start-page: 371
  year: 2017
  ident: 29462_CR77
  publication-title: Am J Hum Genet
  doi: 10.1016/j.ajhg.2017.01.026
  contributor:
    fullname: LR Lloyd-Jones
– volume: 118
  start-page: 1299
  year: 2005
  ident: 29462_CR37
  publication-title: J Cell Sci
  doi: 10.1242/jcs.01726
  contributor:
    fullname: J Sommerville
– volume: 5
  start-page: e123
  year: 2007
  ident: 29462_CR61
  publication-title: PLoS Biology
  doi: 10.1371/journal.pbio.0050123
  contributor:
    fullname: A Lindqvist
– volume: 8
  start-page: 75
  year: 2002
  ident: 29462_CR66
  publication-title: Mol Hum Reprod
  doi: 10.1093/molehr/8.1.75
  contributor:
    fullname: O Khorram
– volume: 7
  year: 2017
  ident: 29462_CR53
  publication-title: Sci Rep
  doi: 10.1038/s41598-017-10098-3
  contributor:
    fullname: S Altmae
– volume: 348
  start-page: 648
  year: 2015
  ident: 29462_CR13
  publication-title: Science
  doi: 10.1126/science.1262110
  contributor:
    fullname: GTExConsortium. Human genomics
– volume: 550
  start-page: 204
  year: 2017
  ident: 29462_CR12
  publication-title: Nature
  doi: 10.1038/nature24277
  contributor:
    fullname: GT Consortium
– volume: 6
  start-page: 351
  year: 1992
  ident: 29462_CR4
  publication-title: Baillieres Clin Obstet Gynaecol
  doi: 10.1016/S0950-3552(05)80092-6
  contributor:
    fullname: MJ Harper
– volume: 5
  start-page: 559
  year: 1999
  ident: 29462_CR47
  publication-title: MHR: Basic science of reproductive medicine
  contributor:
    fullname: S Matsuzaki
– volume: 133
  start-page: 859
  year: 1979
  ident: 29462_CR45
  publication-title: American Journal of Obstetrics and Gynecology
  doi: 10.1016/0002-9378(79)90302-8
  contributor:
    fullname: A Ferenczy
– volume: 9
  start-page: e97311
  year: 2014
  ident: 29462_CR60
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0097311
  contributor:
    fullname: G Vallejo
– volume: 10
  start-page: 879
  year: 2004
  ident: 29462_CR1
  publication-title: Mol Hum Reprod
  doi: 10.1093/molehr/gah121
  contributor:
    fullname: AP Ponnampalam
– volume: 13
  start-page: e1006643
  year: 2017
  ident: 29462_CR67
  publication-title: PLOS Genetics
  doi: 10.1371/journal.pgen.1006643
  contributor:
    fullname: S Kasela
– volume: 508
  start-page: 140
  year: 2012
  ident: 29462_CR62
  publication-title: Gene
  doi: 10.1016/j.gene.2012.07.031
  contributor:
    fullname: E Turkyilmaz
– volume: 48
  start-page: 667
  year: 2016
  ident: 29462_CR36
  publication-title: Nat Genet
  doi: 10.1038/ng.3562
  contributor:
    fullname: TH Cheng
– volume: 4
  year: 2015
  ident: 29462_CR73
  publication-title: Gigascience
  doi: 10.1186/s13742-015-0047-8
  contributor:
    fullname: CC Chang
– volume: 24
  start-page: 198
  year: 2009
  ident: 29462_CR44
  publication-title: Human Reproduction
  doi: 10.1093/humrep/den360
  contributor:
    fullname: D Haouzi
– volume: 67
  start-page: 393
  year: 2004
  ident: 29462_CR46
  publication-title: Archives of Histology and Cytology
  doi: 10.1679/aohc.67.393
  contributor:
    fullname: OD Slayden
– volume: 2015
  start-page: 340218
  year: 2015
  ident: 29462_CR30
  publication-title: Biomed Res Int
  contributor:
    fullname: J Chen
– volume: 8
  start-page: e58419
  year: 2013
  ident: 29462_CR41
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0058419
  contributor:
    fullname: SR Bhagwat
– volume: 30
  start-page: 1665
  year: 2015
  ident: 29462_CR51
  publication-title: Human Reproduction
  doi: 10.1093/humrep/dev117
  contributor:
    fullname: Y Liao
– volume: 12
  start-page: e1005908
  year: 2016
  ident: 29462_CR8
  publication-title: PLoS Genet
  doi: 10.1371/journal.pgen.1005908
  contributor:
    fullname: JE Peters
– volume: 8
  year: 2017
  ident: 29462_CR75
  publication-title: Nat Commun
  doi: 10.1038/s41467-017-01261-5
  contributor:
    fullname: K Watanabe
– volume: 43
  start-page: 51
  year: 2011
  ident: 29462_CR22
  publication-title: Nat Genet
  doi: 10.1038/ng.731
  contributor:
    fullname: JN Painter
– volume: 33
  start-page: 59
  year: 2014
  ident: 29462_CR31
  publication-title: Int J Mol Med
  doi: 10.3892/ijmm.2013.1536
  contributor:
    fullname: XY Shi
– volume: 93
  start-page: 1750
  year: 2010
  ident: 29462_CR28
  publication-title: Fertil Steril
  doi: 10.1016/j.fertnstert.2008.12.058
  contributor:
    fullname: J Meola
– volume: 206
  start-page: 91
  year: 2005
  ident: 29462_CR48
  publication-title: Toxicology
  doi: 10.1016/j.tox.2004.07.005
  contributor:
    fullname: M Pole
– ident: 29462_CR63
  doi: 10.1016/j.scitotenv.2016.07.150
– volume: 68
  start-page: 3165
  year: 2011
  ident: 29462_CR26
  publication-title: Cell Mol Life Sci
  doi: 10.1007/s00018-011-0781-8
  contributor:
    fullname: LB Rivera
– volume: 44
  start-page: 1020
  year: 2012
  ident: 29462_CR38
  publication-title: Nat Genet
  doi: 10.1038/ng.2384
  contributor:
    fullname: Y Shi
– volume: 40
  start-page: 1180
  year: 2014
  ident: 29462_CR57
  publication-title: Journal of Obstetrics and Gynaecology Research
  doi: 10.1111/jog.12392
  contributor:
    fullname: H Okada
– volume: 14
  start-page: 3
  issue: Suppl 2
  year: 1999
  ident: 29462_CR5
  publication-title: Hum Reprod
  doi: 10.1093/humrep/14.suppl_2.3
  contributor:
    fullname: LC Giudice
– volume: 362
  start-page: 2389
  year: 2010
  ident: 29462_CR15
  publication-title: N Engl J Med
  doi: 10.1056/NEJMcp1000274
  contributor:
    fullname: LC Giudice
– volume: 19
  start-page: 1138
  year: 2012
  ident: 29462_CR42
  publication-title: Reprod Sci
  doi: 10.1177/1933719112443877
  contributor:
    fullname: RG Petracco
– volume: 32
  start-page: 893
  year: 2017
  ident: 29462_CR35
  publication-title: Human Reproduction
  doi: 10.1093/humrep/dex006
  contributor:
    fullname: JN Fung
– volume: 8
  year: 2017
  ident: 29462_CR23
  publication-title: Nat Commun
  doi: 10.1038/ncomms15539
  contributor:
    fullname: Y Sapkota
– volume: 31
  start-page: 999
  year: 2016
  ident: 29462_CR20
  publication-title: Hum Reprod
  doi: 10.1093/humrep/dew047
  contributor:
    fullname: SJ Holdsworth-Carson
– volume: 3
  start-page: 239
  year: 2009
  ident: 29462_CR27
  publication-title: J Cell Commun Signal
  doi: 10.1007/s12079-009-0062-6
  contributor:
    fullname: AD Bradshaw
– volume: 25
  start-page: 1432
  year: 2015
  ident: 29462_CR11
  publication-title: Genome Res
  doi: 10.1101/gr.190603.115
  contributor:
    fullname: WL Lowe Jr.
– volume: 108
  start-page: 703
  year: 2017
  ident: 29462_CR59
  publication-title: Fertility and Sterility
  doi: 10.1016/j.fertnstert.2017.07.007
  contributor:
    fullname: P Díaz-Gimeno
– volume: 173
  start-page: 700
  year: 2008
  ident: 29462_CR17
  publication-title: Am J Pathol
  doi: 10.2353/ajpath.2008.071128
  contributor:
    fullname: ML Hull
– volume: 30
  start-page: 1263
  year: 2015
  ident: 29462_CR19
  publication-title: Hum Reprod
  doi: 10.1093/humrep/dev051
  contributor:
    fullname: JN Fung
– volume: 25
  start-page: 5046
  year: 2016
  ident: 29462_CR21
  publication-title: Hum Mol Genet
  contributor:
    fullname: JE Powell
– volume: 12
  start-page: e1005858
  year: 2016
  ident: 29462_CR52
  publication-title: PLOS Genetics
  doi: 10.1371/journal.pgen.1005858
  contributor:
    fullname: CK Burrows
– volume: 20
  start-page: 319
  year: 2004
  ident: 29462_CR64
  publication-title: Immunity
  doi: 10.1016/S1074-7613(04)00046-9
  contributor:
    fullname: L Agostini
– volume: 62
  start-page: 239
  year: 2005
  ident: 29462_CR43
  publication-title: Cellular and Molecular Life Sciences CMLS
  doi: 10.1007/s00018-004-4435-y
  contributor:
    fullname: C Punyadeera
– volume: 1842
  start-page: 1896
  year: 2014
  ident: 29462_CR9
  publication-title: Biochim Biophys Acta
  doi: 10.1016/j.bbadis.2014.04.024
  contributor:
    fullname: HJ Westra
– volume: 33
  start-page: 2225
  year: 2014
  ident: 29462_CR39
  publication-title: Oncogene
  doi: 10.1038/onc.2013.170
  contributor:
    fullname: D Cui
– volume: 518
  start-page: 317
  year: 2015
  ident: 29462_CR14
  publication-title: Nature
  doi: 10.1038/nature14248
  contributor:
    fullname: C Roadmap Epigenomics
– volume: 44
  start-page: 480
  year: 2012
  ident: 29462_CR25
  publication-title: Int J Biochem Cell Biol
  doi: 10.1016/j.biocel.2011.12.021
  contributor:
    fullname: AD Bradshaw
– volume: 57
  start-page: 1143
  year: 2008
  ident: 29462_CR69
  publication-title: Diabetes
  doi: 10.2337/db07-1305
  contributor:
    fullname: H Hakonarson
– volume: 89
  start-page: 2390
  year: 2004
  ident: 29462_CR33
  publication-title: J Clin Endocrinol Metab
  doi: 10.1210/jc.2003-031389
  contributor:
    fullname: GS Daftary
– volume: 1
  start-page: 417
  year: 2015
  ident: 29462_CR24
  publication-title: Cell Syst
  doi: 10.1016/j.cels.2015.12.004
  contributor:
    fullname: A Liberzon
– volume: 14
  start-page: 1328
  year: 1999
  ident: 29462_CR32
  publication-title: Hum Reprod
  doi: 10.1093/humrep/14.5.1328
  contributor:
    fullname: HS Taylor
– volume: 10
  start-page: 252
  year: 2009
  ident: 29462_CR76
  publication-title: Nat Rev Genet
  doi: 10.1038/nrg2538
  contributor:
    fullname: JM Vaquerizas
– volume: 17
  start-page: 1707
  year: 2007
  ident: 29462_CR10
  publication-title: Genome Res
  doi: 10.1101/gr.6981507
  contributor:
    fullname: RB Williams
– volume: 191
  start-page: 107
  year: 2012
  ident: 29462_CR40
  publication-title: Genetics
  doi: 10.1534/genetics.111.136549
  contributor:
    fullname: KK Steffen
– volume: 506
  start-page: 376
  year: 2014
  ident: 29462_CR72
  publication-title: Nature
  doi: 10.1038/nature12873
  contributor:
    fullname: Y Okada
SSID ssj0000529419
Score 2.470514
Snippet Gene expression varies markedly across the menstrual cycle and expression levels for many genes are under genetic control. We analyzed gene expression and...
Abstract Gene expression varies markedly across the menstrual cycle and expression levels for many genes are under genetic control. We analyzed gene expression...
SourceID pubmedcentral
proquest
crossref
pubmed
springer
SourceType Open Access Repository
Aggregation Database
Index Database
Publisher
StartPage 11424
SubjectTerms 38
38/39
45
45/61
631/114/2407
631/208/200
Biological control
Chromosome 1
Chromosome 12
DNA probes
Endometriosis
Endometrium
Gene expression
Gene mapping
Gene silencing
Genetic control
Genetic effects
Genotype & phenotype
Health risks
Humanities and Social Sciences
Menstrual cycle
multidisciplinary
Polycystic ovary syndrome
Probes
Quantitative trait loci
Science
Science (multidisciplinary)
SummonAdditionalLinks – databaseName: Health & Medical Collection (Proquest)
  dbid: 7X7
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Li9UwFA46IrgR33YcJYI7LTZtmsdKRBwGQVcO3F1pXjgwJnemd8T-EX_vnJO293IddFdISJt-J8l55TuEvHGK89A6WRpRyZKb1pdK8b50oCyoYJTXmYnp6zdxcsq_rNrV7HAb5rTKZU_MG7VLFn3k6AmBoxSsGf5hfVFi1SiMrs4lNG6TO6yuBEq1XMmtjwWjWJzp-a5M1aj3A5xXeKeM4dUDLupy3D-PbiiZN3Ml_wqY5nPo-AG5PyuQ9OOE-ENyy8dH5O5UUnJ8TP4gjzQ00cupyDz8dpoCneMwFDPJaR8d9dGlnz7X7KAgQ57633NKbKRIYXyORvtA12mD6UTQaUoZz30HCpruboQ0nA15zHU6H-2IxM80_QIbvI90IUR4Qk6PP3__dFLOtRdK20q5KYUzllXGtloEbo0BPdKHmgXmfAAdT_dtcI22gKhGOuNgrFacWS6tNcKD5fuUHMQU_XNCma-MZobrOkjeaq9s04NZGjirPDz0BXm7INCtJ4qNLofGG9VNeHWAV5fx6saCHC0gdfNyG7qdcBTk9bYZFgpGP_ro0xX2URVYs60SBXk2Ybp9XYOanMAWuYf2tgOScO-3xLMfmYxb5JJfrCDvFrnYfda_Z3H4_1m8IPdqlFH0IVdH5GBzeeVfgvKzMa-yhF8DUa0IZQ
  priority: 102
  providerName: ProQuest
– databaseName: Scholars Portal Open Access Journals
  dbid: M48
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwdV1Nb9QwEB2VIlAviO-mFGQkbhCIs45jHxBCiKpCghMr9RbFji0qLcl2s62aP9Lf2xk72VLa3iLZcZy8sfwmnnkD8K5RQviiKVMjszIVpnCpUqJOGyQLyhvldFBi-vlLHs7Fj6PiaAumckfjB-xvde2ontR8tfh4fjJ8wQX_OaaMq089bkKUKMYpn0DIPB3uwf2cUoEolG-k-1HrG9u5HnNnbr91Bx7OaF-XlF3971Z1g3_eDKP87yw1bFEHj-HRyC3Z12gMT2DLtU_hQaw2OTyDC5KYxia2ivXnERHWeTYe0TAKMmd12zDXNt1fF8p5MDQvx9z5GC3bMlI3XpA_37Nlt6ZII-wUo8lD354hCb4aoeuP-zDmslsMdiBNaNadoXtet2zSSngO84Pvv78dpmNZhtQWZblOZWMsz4wttPTCGoMU0_mce944j_RP14VvZtoi2JqUjr2xWgluRWmtkQ6d4hew3Xat2wXGXWY0N0LnvhSFdsrOavRYveCZw4s6gfcTAtUyqm9U4dR8pqoIXYXQVQG6akhgfwKpmgypyrMSKRh6wSKBt5tmXEN0MFK3rjulPipDR7dQMoGXEdPN4yZjSKC8hvamA-lzX29pj_8EnW4ZqoHxBD5MdnE1rbvfYu_OKbyCnZwslf4sZ_uwvV6dutdIidbmTbDzS2dpC54
  priority: 102
  providerName: Scholars Portal
– databaseName: SpringerOpen
  dbid: C6C
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV1Na9wwEB2alEAupZ-J27So0FtratmyLB3L0iUU2lMXcjOWLJHARl7iTan_SH9vZ2TvLtskh94MGn--MXqjGb0B-NAqIXzZVqmRWZUKU7pUKdGkLZIF5Y1yOioxff8hzxfi20V5Mcnk0F6Yvfx9oT73OMHQJjBOewWEzNPhAB7jHKzIg2dytl1PoYyV4HraF3P_qftzzx1Cebcu8p_kaJxz5k_hyUQW2ZcR3WfwyIXncDS2jxxewB_SjMYhdjM2lMdPzDrPppwLo6px1oSWudB21y7252DoL46531P5a2AkV7ykAL1nq25NpUNoNJaHR9ueIavdXaHrr_p4zVW3HOxAIs-s-4XxdhPYRvzgJSzmX3_OztOpz0Jqy6pap7I1lmfGllp6YY1Bzuh8zj1vnUc-p5vSt4W2iJ4m6WJvrFaCW1FZa6TDKPcVHIYuuFNg3GVGcyN07itRaqds0WAI6gXPHB40CXzcIFCvRjmNOqbBC1WPeNWIVx3xqocEzjYg1dOv1dd5ViGnwrBWJPB-O4w_BWU6muC6W7JRGUaupZIJnIyYbm9XEGuTNFLtob01IMHt_ZFwdRmFt2Vs78UT-LTxi91jPfwWr__P_A0c5-SztH6cncHh-ubWvUXiszbvosf_BXjnAd0
  priority: 102
  providerName: Springer Nature
Title Genetic regulation of disease risk and endometrial gene expression highlights potential target genes for endometriosis and polycystic ovarian syndrome
URI https://link.springer.com/article/10.1038/s41598-018-29462-y
https://www.ncbi.nlm.nih.gov/pubmed/30061686
https://www.proquest.com/docview/2079935494
https://search.proquest.com/docview/2080840586
https://pubmed.ncbi.nlm.nih.gov/PMC6065421
Volume 8
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1fa9wwDBdtx0Zfxv4vW3d4sLctvThxHPtxO1rK4EoZK9xbiB2bHdw5R3MdyxfZ553sJNd2ZS97CQkWjhNJWLKknwA-1IIxm9dFrHhSxEzlJhaCVXGNxoKwShgZkJjm5_zskn1d5Is9yMdamJC0r9Xy2K3Wx275I-RWbtZ6OuaJTS_mMx7aLNHpPuyjgN5y0XtA71QyKocCmSQT0xY3KV9IRn29AeNp3B3Co8xv3tyXUN_ej-4ZmfdzJf8KmIZ96PQJPB4MSPK5X-hT2DPuGTzsW0p2z-G3x5HGIXLVN5nH304aS4Y4DPGZ5KRyNTGubtYm9OwgKEOGmF9DSqwjHsJ45Z32lmyarU8nQqI-ZTzQtgQt3ZsZmnbZhjk3zarTnQd-Js1P9MErR0ZAhBdweXryfXYWD70XYp0XxTbmtdI0UTqX3DKtFNqRxqbU0tpYtPFklds6kxo5Kj2csVVaCkY1K7RW3KDn-xIOXOPMayDUJEpSxWRqC5ZLI3RWoVtqGU0M3lQRfBw5UG56iI0yhMYzUfasK5F1ZWBd2UVwNDKpHNStLdOkQDsLXV0WwfvdMCqKj35UzjTXnkYk6M3mgkfwqufp7nWjMERQ3OH2jsCDcN8dQdkMYNyDLEbwaZSLm2X9-yve_PeL3sJh6iXZHy8nR3Cwvbo279Au2qoJasOimMCDLyfnF9_wacZnk3DGgNc5E5OgJ38Aa0MWYA
link.rule.ids 230,315,730,783,787,867,888,12069,21401,24331,27937,27938,31732,31733,33757,33758,41133,42202,43323,43818,51589,53805,53807,74080,74637
linkProvider National Library of Medicine
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Lb9QwELagCMGl4k1oASNxA4t44zj2qUKIaoG2p1baWxS_RKUSL80WkT_C7-2Mk-xqqeAWyZYT5xvb8_I3hLx1SohQuooZmVdMmNIzpUTDHCgLKhjldWJiOj6R8zPxdVEuRodbN6ZVTnti2qhdtOgjR08IHKVgzYiD5U-GVaMwujqW0LhN7iAPF8p5tajWPhaMYgmux7syeaE-dHBe4Z0yjlcPhJyxfvs8uqFk3syV_Ctgms6hwwdkd1Qg6ccB8Yfklm8fkbtDScn-MfmDPNLQRC-HIvPw22kMdIzDUMwkp03rqG9d_OFTzQ4KMuSp_z2mxLYUKYwv0Gjv6DKuMJ0IOg0p46lvR0HT3YwQu_MujbmMF73tkfiZxl9ggzctnQgRnpCzw8-nn-ZsrL3AbFlVKyadsTw3ttQyCGsM6JE-zHjgzgfQ8XRTBldoC4hqpDMOxmoluBWVtUZ6sHyfkp02tv45odznRnMj9CxUotRe2aIBszQInnt4aDLybkKgXg4UG3UKjReqHvCqAa864VX3GdmfQKrH5dbVG-HIyJt1MywUjH40rY9X2EflYM2WSmbk2YDp-nUFanISW6ottNcdkIR7u6U9_57IuGUq-cUz8n6Si81n_XsWL_4_i9fk3vz0-Kg--nLybY_cn6G8oj853yc7q8sr_xIUoZV5laT9Gs85C0w
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Lb9QwELagFagXxLMNtGAkbhA13jiOfUK0dFVeqwpRqbcodmxRqcRLs0Xkj_B7O-M4u1oquEXyyEn0je15-RtCXjWSc1c0ZapFVqZcFzaVktdpA8aCdFpaFZiYvszE8Sn_eFacxfqnLpZVjnti2KgbbzBGjpEQOErBm-H7LpZFnLyfvp3_TLGDFGZaYzuN22Sz5CIHR2zz4Gh28nUZccGcFmcq3pzJcrnfwemFN8wYXkTgYpL266fTDZPzZuXkX-nTcCpN75N70Zyk7wb8H5Bbtn1I7gwNJvtH5A-ySsMQvRxazgMI1DsaszIU68pp3TbUto3_YUMHDwoaZan9HQtkW4qExhfownd07hdYXARCQwF5kO0o2L2rGXx33oU55_6iNz3SQFP_CzzyuqUjPcJjcjo9-nZ4nMZODKkpynKRikYblmlTKOG40RqsSusmzLHGOrD4VF24JlcG8FVIbuy0UZIzw0tjtLDgBz8hG61v7Q6hzGZaMc3VxJW8UFaavAYn1XGWWXioE_J6RKCaD4QbVUiU57Ia8KoAryrgVfUJ2R1BquLi66qVqiTk5XIYlg3mQurW-iuUkRn4toUUCdkeMF2-Lke7TuBIuYb2UgApuddH2vPvgZpbhAZgLCFvRr1Yfda__-Lp___iBbkLql59_jD79IxsTVBdMbic7ZKNxeWV3QOraKGfR3W_BrMqEO8
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Genetic+regulation+of+disease+risk+and+endometrial+gene+expression+highlights+potential+target+genes+for+endometriosis+and+polycystic+ovarian+syndrome&rft.jtitle=Scientific+reports&rft.au=Fung%2C+Jenny+N&rft.au=Mortlock%2C+Sally&rft.au=Girling%2C+Jane+E&rft.au=Holdsworth-Carson%2C+Sarah+J&rft.date=2018-07-30&rft.eissn=2045-2322&rft.volume=8&rft.issue=1&rft.spage=11424&rft_id=info:doi/10.1038%2Fs41598-018-29462-y&rft_id=info%3Apmid%2F30061686&rft.externalDocID=30061686
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2045-2322&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2045-2322&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2045-2322&client=summon