Imaging local brain activity of multiple freely moving mice sharing the same environment

• Published in: Scientific reports Vol. 9; no. 1; p. 7460
• Main Authors: Inagaki, Shigenori, Agetsuma, Masakazu, Ohara, Shinya, Iijima, Toshio, Yokota, Hideo, Wazawa, Tetsuichi, Arai, Yoshiyuki, Nagai, Takeharu
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 16.05.2019; Nature Publishing Group
• Subjects: 59/5; 631/1647/245/2222; 631/378/2613; 64/60; Animals; Cells, Cultured; Environment; Fluorescence Resonance Energy Transfer - methods; Humanities and Social Sciences; Information processing; Luminescent Proteins - genetics; Luminescent Proteins - metabolism; Male; Membrane Potentials; Mental disorders; Mice; Mice, Inbred C57BL; Movement; multidisciplinary; Nervous system; Neuroimaging; Neurosciences; Optogenetics - methods; Patch-Clamp Techniques - methods; Phosphoric Monoester Hydrolases - genetics; Phosphoric Monoester Hydrolases - metabolism; Science; Science (multidisciplinary); Visual cortex; Visual Cortex - diagnostic imaging; Visual Cortex - metabolism; Visual Cortex - physiology

Electrophysiological field potential dynamics have been widely used to investigate brain functions and related psychiatric disorders. Considering recent demand for its applicability to freely moving subjects, especially for animals in a group and socially interacting with each other, here we propose...