Genetic investigation of glycosylphosphatidylinositol (GPI) anchored Bd37 orthologs in Babesia divergens group and potential use of recombinant protein for ecological survey in deer

• Published in: Journal of Veterinary Medical Science Vol. 86; no. 11; pp. 1185 - 1197
• Main Authors: ZAMOTO-NIIKURA, Aya, HAGIWARA, Katsuro, MORIKAWA, Shigeru, HANAKI, Ken-Ichi, IMAOKA, Koichi
• Format: Journal Article
• Language: English
• Published: Japan JAPANESE SOCIETY OF VETERINARY SCIENCE 2024; Japan Science and Technology Agency; The Japanese Society of Veterinary Science
• Subjects: Amino Acid Sequence; Animals; Antigens; Babesia - genetics; Babesia divergens; Babesia divergens Asia lineage; Babesiosis; Babesiosis - parasitology; Deer - parasitology; Divergence; ecological survey; Enzyme-linked immunosorbent assay; Epitopes; Glycosylphosphatidylinositol; glycosylphosphatidylinositol (GPI); Glycosylphosphatidylinositols; Japan; Lymphocytes B; Polymerase chain reaction; Protozoan Proteins - genetics; Public Health; Recombinant Proteins - genetics; rRNA 18S; sika deer; Japan; Babesia divergens Asia lineage; glycosylphosphatidylinositol (GPI); ecological survey; sika deer

The Babesia divergens/B. capreoli group includes parasites with confirmed or possible zoonotic potential to cause human babesiosis. Currently, diagnostic antigen of the group has not been established. In this study, we investigated the ortholog of Bd37, a glycosylphosphatidylinositol (GPI)-anchored...