FGF-7 Dictates Osteocyte Cell Processes Through Beta-Catenin Transduction

• Published in: Scientific reports Vol. 8; no. 1; pp. 14792 - 10
• Main Authors: Liu, Xiao-Yu, Li, Xin, Bai, Ming-Ru, Chen, Xia, Wang, Cheng-Lin, Xie, Jing, Ye, Ling
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 04.10.2018; Nature Publishing Group; Nature Portfolio
• Subjects: 13/21; 13/51; 14/19; 631/80/2373/2238; 631/80/84/2334; Anti-connexin Antibodies; Antibodies; Autocrine signalling; Bone Cell Behavior; Bone growth; Bone remodeling; Bones; Canonical FGFs; Cloning; Communication; Connexin 43; Fibroblast growth factor 7; Fibroblast growth factor receptor 7; Fibroblasts; Gap junctions; Growth factors; Humanities and Social Sciences; Kinases; mRNA; multidisciplinary; Nuclear transport; Osteocyte Cell Processes; Osteocytes; Osteogenesis; Paracrine signalling; Roles; Science; Science (multidisciplinary); Signal transduction; Stem cells; Tibial Tissue; Translocation; β-Catenin; Tibial Tissue; Osteocyte Cell Processes; Anti-connexin Antibodies; Canonical FGFs; Bone Cell Behavior

It is well recognized that osteocytes communicate with each other via gap junctions and that connxin43 (Cx43) shows its great potential in gap junction for the contribution enabling transmission of small molecules and operating in an autocrine/a paracrine manner. Fibroblast growth factors (FGFs) pla...