Effects of bowel preparation on the human gut microbiome and metabolome

• Published in: Scientific reports Vol. 9; no. 1; p. 4042
• Main Authors: Nagata, Naoyoshi, Tohya, Mari, Fukuda, Shinji, Suda, Wataru, Nishijima, Suguru, Takeuchi, Fumihiko, Ohsugi, Mitsuru, Tsujimoto, Tetsuro, Nakamura, Tomoka, Shimomura, Akira, Yanagisawa, Naohiro, Hisada, Yuya, Watanabe, Kazuhiro, Imbe, Koh, Akiyama, Junichi, Mizokami, Masashi, Miyoshi-Akiyama, Tohru, Uemura, Naomi, Hattori, Masahira
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 11.03.2019; Nature Publishing Group
• Subjects: 45; 631/326; 631/326/107; 692/4020/1394; 692/4020/2741/2135; 82; 82/58; Capillary electrophoresis; Correlation coefficient; Digestive system; Feces - microbiology; Gastrointestinal Microbiome - genetics; Gut microbiota; Humanities and Social Sciences; Humans; Intestinal microflora; Intestine; Mass Spectrometry; Mass spectroscopy; Metabolites; Metabolome - genetics; Metabolomics; Microbiomes; Microbiota; Microbiota - genetics; multidisciplinary; RNA, Ribosomal, 16S - genetics; rRNA 16S; Science; Science (multidisciplinary)

Large bowel preparation may cause a substantial change in the gut microbiota and metabolites. Here, we included a bowel prep group and a no-procedure control group and evaluated the effects of bowel prep on the stability of the gut microbiome and metabolome as well as on recovery. Gut microbiota and...