Immunological hallmarks of stromal cells in the tumour microenvironment

Key Points Non-haematopoietic stromal cells in the tumour microenvironment actively interact with infiltrating leukocytes. Emerging evidence also suggests that the stromal compartment can shape antitumour immunity and responsiveness to immunotherapy. Dysfunctional endothelial cells and aberrant peri...

Full description

Saved in:

Bibliographic Details
Published in	Nature reviews. Immunology Vol. 15; no. 11; pp. 669 - 682
Main Authors	Turley, Shannon J., Cremasco, Viviana, Astarita, Jillian L.
Format	Journal Article
Language	English
Published	London Nature Publishing Group UK 01.11.2015 Nature Publishing Group
Subjects	631/250/2520 631/250/580 631/67/327 Adipocytes Animals Antigens Biomedicine Cancer Care and treatment Cell Communication Cell Movement Cytotoxicity, Immunologic Dendritic cells Extracellular matrix Extracellular Matrix - physiology Fibroblasts Fibroblasts - physiology Growth factors Health aspects Humans Immunology Immunotherapy Leukocytes Leukocytes - physiology Lymphatic system Medical prognosis Mesenchymal Stromal Cells - physiology review-article Stem cells Stromal Cells - immunology Tumor Microenvironment Tumors United States United States > US Massachusetts
Online Access	Get full text

Cover

Loading…

Abstract	Key Points Non-haematopoietic stromal cells in the tumour microenvironment actively interact with infiltrating leukocytes. Emerging evidence also suggests that the stromal compartment can shape antitumour immunity and responsiveness to immunotherapy. Dysfunctional endothelial cells and aberrant pericyte coverage in tumour blood vessels results in tortuous and leaky vessels, which greatly impinge on leukocyte infiltration. Diapedesis of effector immune cells is further limited by the reduced expression of endothelial adhesive molecules. Fibroblasts contribute to shaping the immune cell populations in tumours by secreting chemokines that can selectively repel effector T cells while favouring the recruitment of immunosuppressive cells. Stromal cells in the tumour microenvironment can also actively hinder antitumour immunity by several mechanisms, including expression of inhibitory receptors, production of molecules that induce T cell apoptosis and secretion of immunosuppressive factors. Overcoming immune suppression is of the upmost importance for cancer treatment. In light of the increasing evidence that suggests a role for the tumour stroma in limiting antitumour immune responses, we anticipate that therapies targeting stromal cells in the tumour microenvironment will be likely to provide enormous benefits. Emerging evidence suggests that the stroma of the tumour microenvironment can shape antitumour immunity and responsiveness to immunotherapy. The stromal cells and the signals they produce that influence tumour-infiltrating leukocytes, as well as the implications for cancer treatment, are reviewed here. A dynamic and mutualistic interaction between tumour cells and the surrounding stroma promotes the initiation, progression, metastasis and chemoresistance of solid tumours. Far less understood is the relationship between the stroma and tumour-infiltrating leukocytes; however, emerging evidence suggests that the stromal compartment can shape antitumour immunity and responsiveness to immunotherapy. Thus, there is growing interest in elucidating the immunomodulatory roles of the stroma that evolve within the tumour microenvironment. In this Review, we discuss the evidence that stromal determinants interact with leukocytes and influence antitumour immunity, with emphasis on the immunological attributes of stromal cells that may foster their protumorigenic function.
AbstractList	A dynamic and mutualistic interaction between tumour cells and the surrounding stroma promotes the initiation, progression, metastasis and chemoresistance of solid tumours. Far less understood is the relationship between the stroma and tumour-infiltrating leukocytes; however, emerging evidence suggests that the stromal compartment can shape antitumour immunity and responsiveness to immunotherapy. Thus, there is growing interest in elucidating the immunomodulatory roles of the stroma that evolve within the tumour microenvironment. In this Review, we discuss the evidence that stromal determinants interact with leukocytes and influence antitumour immunity, with emphasis on the immunological attributes of stromal cells that may foster their protumorigenic function. Key Points Non-haematopoietic stromal cells in the tumour microenvironment actively interact with infiltrating leukocytes. Emerging evidence also suggests that the stromal compartment can shape antitumour immunity and responsiveness to immunotherapy. Dysfunctional endothelial cells and aberrant pericyte coverage in tumour blood vessels results in tortuous and leaky vessels, which greatly impinge on leukocyte infiltration. Diapedesis of effector immune cells is further limited by the reduced expression of endothelial adhesive molecules. Fibroblasts contribute to shaping the immune cell populations in tumours by secreting chemokines that can selectively repel effector T cells while favouring the recruitment of immunosuppressive cells. Stromal cells in the tumour microenvironment can also actively hinder antitumour immunity by several mechanisms, including expression of inhibitory receptors, production of molecules that induce T cell apoptosis and secretion of immunosuppressive factors. Overcoming immune suppression is of the upmost importance for cancer treatment. In light of the increasing evidence that suggests a role for the tumour stroma in limiting antitumour immune responses, we anticipate that therapies targeting stromal cells in the tumour microenvironment will be likely to provide enormous benefits. Emerging evidence suggests that the stroma of the tumour microenvironment can shape antitumour immunity and responsiveness to immunotherapy. The stromal cells and the signals they produce that influence tumour-infiltrating leukocytes, as well as the implications for cancer treatment, are reviewed here. A dynamic and mutualistic interaction between tumour cells and the surrounding stroma promotes the initiation, progression, metastasis and chemoresistance of solid tumours. Far less understood is the relationship between the stroma and tumour-infiltrating leukocytes; however, emerging evidence suggests that the stromal compartment can shape antitumour immunity and responsiveness to immunotherapy. Thus, there is growing interest in elucidating the immunomodulatory roles of the stroma that evolve within the tumour microenvironment. In this Review, we discuss the evidence that stromal determinants interact with leukocytes and influence antitumour immunity, with emphasis on the immunological attributes of stromal cells that may foster their protumorigenic function.
Audience	Academic
Author	Astarita, Jillian L. Cremasco, Viviana Turley, Shannon J.
Author_xml	– sequence: 1 givenname: Shannon J. surname: Turley fullname: Turley, Shannon J. email: turley.shannon@gene.com organization: Department of Cancer Immunology, Genentech – sequence: 2 givenname: Viviana surname: Cremasco fullname: Cremasco, Viviana organization: Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Exploratory Immuno-Oncology, Novartis Institutes for BioMedical Research – sequence: 3 givenname: Jillian L. surname: Astarita fullname: Astarita, Jillian L. organization: Department of Cancer Immunology, Genentech
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/26471778$$D View this record in MEDLINE/PubMed
BookMark	eNqNkltrVDEQx4NU7EXxG8gBwcvD1uRMbuexFK0LBcHLc8iek-ym5lKTHNFvb5aubbf4IHmYMPObYf4zc4wOYooGoecEnxIM8l3MDgbcP0JHhAq6IIKSg9s_wCE6LuUKY8Jb5Ak67DkVRAh5hC6WIcwx-bR2o_bdRnsfdP5eumS7UnMKzTka70vnYlc3pqtzSHPughtzMvGnyykGE-tT9NhqX8yznT1B3z68_3r-cXH56WJ5fna5GJkQtTWjhSWW6KEfRjowwzADysHKHmM8MYatHBlfrbAUIDEjPRk1wCQmPgwWAE7Qm5u61zn9mE2pKriybVBHk-aimiqQgLEk_4H2ggLjjDf05QP0qomMTUijuAAKfCB31Fp7o1y0qWY9bouqMwpAJfRYNur0H1R7k2lDa2uzrvn3Et7uJTSmml91redS1PLL53321T12Y7Svm5L8XF2KZR98fQO2NZWSjVXX2bXN_lYEq-3JqN3JNPLFTvu8Cma65f7eyN0cSwvFtcn3hvOg1h9KwcVW
CitedBy_id	crossref_primary_10_1093_annonc_mdw217 crossref_primary_10_1126_sciadv_add3599 crossref_primary_10_1158_0008_5472_CAN_18_0327 crossref_primary_10_1038_s41419_018_0485_1 crossref_primary_10_1038_s41467_018_05696_2 crossref_primary_10_1016_j_mtadv_2021_100160 crossref_primary_10_3389_fcell_2023_1240390 crossref_primary_10_1016_j_bbcan_2019_01_005 crossref_primary_10_1016_j_cotox_2024_100459 crossref_primary_10_1158_2326_6066_CIR_20_0074 crossref_primary_10_1016_j_omtn_2017_06_009 crossref_primary_10_1186_s40425_018_0418_7 crossref_primary_10_1016_j_drudis_2021_02_006 crossref_primary_10_1016_j_bbrc_2019_03_136 crossref_primary_10_1038_s41401_020_0400_z crossref_primary_10_3389_fimmu_2024_1302761 crossref_primary_10_1016_j_bbcan_2016_03_005 crossref_primary_10_1016_j_jep_2017_09_043 crossref_primary_10_1155_2022_2910491 crossref_primary_10_1038_srep44357 crossref_primary_10_1186_s12885_023_10923_1 crossref_primary_10_3390_cells12081145 crossref_primary_10_3390_genes12101535 crossref_primary_10_4137_CMO_S41271 crossref_primary_10_1016_j_intimp_2024_111549 crossref_primary_10_1155_2018_7628763 crossref_primary_10_3389_fimmu_2022_942765 crossref_primary_10_4251_wjgo_v16_i5_1705 crossref_primary_10_4254_wjh_v16_i4_537 crossref_primary_10_18632_oncotarget_9130 crossref_primary_10_1155_2022_9451480 crossref_primary_10_2147_IJGM_S327765 crossref_primary_10_1007_s00011_021_01494_7 crossref_primary_10_1080_2162402X_2018_1424612 crossref_primary_10_3389_fonc_2022_966511 crossref_primary_10_1038_s41419_023_05806_z crossref_primary_10_3389_fphar_2022_941270 crossref_primary_10_1177_1559325819891004 crossref_primary_10_3390_cancers13030461 crossref_primary_10_1186_s12885_019_6333_6 crossref_primary_10_1080_17460441_2021_1912731 crossref_primary_10_1002_stem_2666 crossref_primary_10_1007_s10142_023_01184_z crossref_primary_10_1038_s41698_024_00540_x crossref_primary_10_1002_jcp_29494 crossref_primary_10_1038_s41419_019_1618_x crossref_primary_10_3390_ijms21207785 crossref_primary_10_1002_adtp_202200040 crossref_primary_10_1084_jem_20190634 crossref_primary_10_1093_bioinformatics_btaa770 crossref_primary_10_3390_cancers16081568 crossref_primary_10_1002_adhm_202102479 crossref_primary_10_1089_dna_2022_0644 crossref_primary_10_3390_cancers13215553 crossref_primary_10_1038_s41577_023_00884_8 crossref_primary_10_1038_s41416_021_01331_y crossref_primary_10_1186_s12885_018_5082_2 crossref_primary_10_2147_IJN_S451151 crossref_primary_10_3389_fimmu_2022_895110 crossref_primary_10_3389_fonc_2022_836389 crossref_primary_10_3389_fcell_2022_1059715 crossref_primary_10_3389_fcell_2020_545126 crossref_primary_10_1002_1878_0261_12410 crossref_primary_10_1016_j_tcb_2020_02_005 crossref_primary_10_1007_s12094_020_02519_z crossref_primary_10_1155_2018_3767482 crossref_primary_10_3390_cancers13020211 crossref_primary_10_1016_j_pathophys_2016_06_001 crossref_primary_10_1002_1878_0261_12779 crossref_primary_10_1080_10717544_2020_1831103 crossref_primary_10_1126_sciadv_adf8522 crossref_primary_10_1016_j_addr_2018_01_005 crossref_primary_10_1038_s41525_021_00249_x crossref_primary_10_3390_cancers15112971 crossref_primary_10_1016_j_talanta_2017_06_038 crossref_primary_10_3389_fcell_2021_749157 crossref_primary_10_1016_j_slasd_2023_12_003 crossref_primary_10_1016_j_cej_2024_151773 crossref_primary_10_1039_C9CS00773C crossref_primary_10_1186_s13046_021_02235_8 crossref_primary_10_3389_fimmu_2020_01820 crossref_primary_10_1038_s41581_021_00474_8 crossref_primary_10_1016_j_cell_2017_04_014 crossref_primary_10_1021_acsami_0c15679 crossref_primary_10_3389_fgene_2022_943849 crossref_primary_10_3390_ijms19030799 crossref_primary_10_1002_smtd_202201404 crossref_primary_10_2147_IJGM_S348343 crossref_primary_10_1038_s41568_023_00556_8 crossref_primary_10_1186_s13046_019_1172_5 crossref_primary_10_3389_fonc_2020_574937 crossref_primary_10_1002_adhm_202001680 crossref_primary_10_1002_mog2_24 crossref_primary_10_1016_j_celrep_2020_107628 crossref_primary_10_2147_CMAR_S279684 crossref_primary_10_1016_j_matt_2023_09_013 crossref_primary_10_1002_advs_202302558 crossref_primary_10_1002_adma_201805888 crossref_primary_10_1038_s41598_023_37300_z crossref_primary_10_1360_SSC_2022_0158 crossref_primary_10_1111_jdv_15992 crossref_primary_10_3389_fgene_2022_1067524 crossref_primary_10_3390_ijms20061263 crossref_primary_10_1002_tox_24177 crossref_primary_10_1080_2162402X_2017_1373237 crossref_primary_10_3389_fonc_2017_00003 crossref_primary_10_1158_2326_6066_CIR_18_0436 crossref_primary_10_1186_s13046_022_02484_1 crossref_primary_10_1245_s10434_021_11155_y crossref_primary_10_1002_cam4_5455 crossref_primary_10_3390_cancers12082118 crossref_primary_10_1039_D2LC00597B crossref_primary_10_3390_cancers15133506 crossref_primary_10_1186_s12935_021_01939_3 crossref_primary_10_1186_s12943_022_01670_1 crossref_primary_10_1158_2326_6066_CIR_23_0205 crossref_primary_10_3389_fgene_2023_1186862 crossref_primary_10_12998_wjcc_v9_i16_3880 crossref_primary_10_1089_ars_2023_0340 crossref_primary_10_1016_j_cclet_2020_12_009 crossref_primary_10_1186_s12967_021_02952_w crossref_primary_10_1111_sji_13327 crossref_primary_10_3389_fimmu_2024_1336476 crossref_primary_10_1038_s41467_021_24564_0 crossref_primary_10_1016_j_biomaterials_2018_04_016 crossref_primary_10_1080_10428194_2021_1894648 crossref_primary_10_1002_smll_202201298 crossref_primary_10_3390_cancers12113170 crossref_primary_10_1007_s00432_022_04255_z crossref_primary_10_18632_aging_204707 crossref_primary_10_1002_adfm_202311914 crossref_primary_10_1007_s13577_018_0211_4 crossref_primary_10_1016_j_jconrel_2020_05_039 crossref_primary_10_3390_cancers12030757 crossref_primary_10_3390_cancers16071413 crossref_primary_10_1186_s12935_022_02614_x crossref_primary_10_3390_cancers13020227 crossref_primary_10_1126_scitranslmed_adh8005 crossref_primary_10_1186_s13058_020_01282_x crossref_primary_10_3390_mi12050535 crossref_primary_10_3389_fonc_2021_575457 crossref_primary_10_2174_1381612829666221207112438 crossref_primary_10_1038_s41577_019_0269_6 crossref_primary_10_1111_cpr_12399 crossref_primary_10_3389_fimmu_2022_819807 crossref_primary_10_3389_fgene_2022_974416 crossref_primary_10_1038_s41467_021_25057_w crossref_primary_10_1038_s41525_023_00381_w crossref_primary_10_1007_s10238_023_01164_4 crossref_primary_10_1016_j_ccell_2022_09_013 crossref_primary_10_1155_2023_2480493 crossref_primary_10_1002_adma_202106390 crossref_primary_10_1080_2162402X_2018_1433982 crossref_primary_10_18632_oncotarget_8098 crossref_primary_10_1016_j_lfs_2021_119848 crossref_primary_10_3389_fonc_2021_591106 crossref_primary_10_3389_fonc_2022_1087753 crossref_primary_10_1021_acs_nanolett_9b02306 crossref_primary_10_7554_eLife_78616 crossref_primary_10_1016_j_chempr_2023_12_019 crossref_primary_10_1016_j_smim_2018_01_002 crossref_primary_10_18632_oncotarget_14374 crossref_primary_10_3389_fimmu_2017_01848 crossref_primary_10_3390_cells11060947 crossref_primary_10_3389_fimmu_2023_1125203 crossref_primary_10_1111_cpr_13115 crossref_primary_10_1016_j_clinre_2022_101877 crossref_primary_10_1136_gutjnl_2023_330049 crossref_primary_10_18632_oncotarget_27675 crossref_primary_10_1016_j_ijpharm_2021_120310 crossref_primary_10_1111_imr_12989 crossref_primary_10_3390_cells9020480 crossref_primary_10_1073_pnas_2214211120 crossref_primary_10_1016_j_bbrc_2018_02_097 crossref_primary_10_3390_cancers16030480 crossref_primary_10_1002_adhm_202001240 crossref_primary_10_1038_s41388_018_0141_3 crossref_primary_10_18632_aging_203833 crossref_primary_10_1002_adfm_201909032 crossref_primary_10_1186_s41065_023_00263_2 crossref_primary_10_3389_fgene_2022_929870 crossref_primary_10_1007_s00262_018_2245_6 crossref_primary_10_1111_cpr_13592 crossref_primary_10_3389_fcell_2021_762029 crossref_primary_10_3389_fimmu_2018_01150 crossref_primary_10_1016_j_molimm_2019_11_008 crossref_primary_10_1016_j_trecan_2019_09_009 crossref_primary_10_1002_adma_201803618 crossref_primary_10_1172_jci_insight_133977 crossref_primary_10_1111_odi_14617 crossref_primary_10_3389_fcell_2020_00447 crossref_primary_10_1158_0008_5472_CAN_16_2337 crossref_primary_10_3892_ijo_2016_3540 crossref_primary_10_1088_1742_6596_2058_1_012028 crossref_primary_10_3389_fphar_2017_00561 crossref_primary_10_1016_j_biomaterials_2018_09_043 crossref_primary_10_1186_s13027_023_00507_w crossref_primary_10_1007_s00262_017_1966_2 crossref_primary_10_1016_j_critrevonc_2024_104430 crossref_primary_10_1016_j_jcmgh_2023_07_001 crossref_primary_10_1016_j_jconrel_2021_04_024 crossref_primary_10_3390_ijms22115906 crossref_primary_10_1155_2021_5551036 crossref_primary_10_1002_smtd_201700347 crossref_primary_10_3389_fonc_2021_682932 crossref_primary_10_3389_fimmu_2021_762243 crossref_primary_10_3389_fmolb_2023_1150362 crossref_primary_10_1016_j_ymthe_2021_11_015 crossref_primary_10_3390_cells10051142 crossref_primary_10_1096_fj_202002232R crossref_primary_10_1371_journal_pone_0260800 crossref_primary_10_1155_2018_7530619 crossref_primary_10_1038_s41416_020_01222_8 crossref_primary_10_1038_s41422_024_00946_z crossref_primary_10_1158_2326_6066_CIR_18_0086 crossref_primary_10_20517_cdr_2023_84 crossref_primary_10_1016_j_ccell_2023_12_021 crossref_primary_10_1021_acsnano_1c11578 crossref_primary_10_3389_fimmu_2022_945516 crossref_primary_10_3389_fmolb_2021_679031 crossref_primary_10_3390_cancers12102916 crossref_primary_10_1186_s43556_023_00126_2 crossref_primary_10_3389_fimmu_2020_01689 crossref_primary_10_1021_acsnano_9b03978 crossref_primary_10_1038_s41423_023_00980_8 crossref_primary_10_1038_s41698_020_00136_1 crossref_primary_10_1007_s10147_022_02249_y crossref_primary_10_1186_s12864_019_6412_8 crossref_primary_10_1016_j_biopha_2022_113618 crossref_primary_10_3389_fimmu_2022_740960 crossref_primary_10_1038_s41467_023_39762_1 crossref_primary_10_3389_fgene_2022_853648 crossref_primary_10_1186_s12967_022_03510_8 crossref_primary_10_1186_s41181_019_0069_0 crossref_primary_10_3390_ijms17111958 crossref_primary_10_1038_nri_2016_80 crossref_primary_10_1158_1078_0432_CCR_18_2243 crossref_primary_10_1242_bio_059949 crossref_primary_10_1038_s41598_020_75541_4 crossref_primary_10_1016_j_xcrm_2023_101121 crossref_primary_10_14348_molcells_2023_0079 crossref_primary_10_1016_j_cej_2023_142495 crossref_primary_10_1053_j_gastro_2019_09_045 crossref_primary_10_1080_2162402X_2017_1414129 crossref_primary_10_1158_2326_6066_CIR_18_0098 crossref_primary_10_3389_fimmu_2022_868813 crossref_primary_10_1016_j_ijrobp_2021_05_014 crossref_primary_10_1186_s40425_018_0376_0 crossref_primary_10_3390_molecules27010137 crossref_primary_10_7554_eLife_58688 crossref_primary_10_2174_1568026619666191011162955 crossref_primary_10_1021_acsnano_0c03776 crossref_primary_10_3390_cancers12102902 crossref_primary_10_1016_j_intimp_2024_112340 crossref_primary_10_3390_cancers13246219 crossref_primary_10_1038_onc_2016_217 crossref_primary_10_1007_s00262_017_2081_0 crossref_primary_10_1016_j_jare_2021_02_002 crossref_primary_10_1186_s13045_019_0753_2 crossref_primary_10_1016_j_ejbt_2023_10_001 crossref_primary_10_1186_s12951_022_01586_4 crossref_primary_10_1016_j_csbj_2023_04_016 crossref_primary_10_1002_bit_27882 crossref_primary_10_1158_1535_7163_MCT_21_0335 crossref_primary_10_1016_j_crmeth_2021_100072 crossref_primary_10_1002_jbt_23448 crossref_primary_10_1002_cyto_b_21880 crossref_primary_10_3389_fimmu_2017_01129 crossref_primary_10_1016_j_cub_2020_06_081 crossref_primary_10_1016_j_phrs_2017_02_011 crossref_primary_10_1186_s12885_022_09673_3 crossref_primary_10_1080_14712598_2017_1271874 crossref_primary_10_1007_s00441_016_2471_1 crossref_primary_10_1158_1078_0432_CCR_17_2687 crossref_primary_10_1038_s41416_020_01201_z crossref_primary_10_3389_fimmu_2022_850358 crossref_primary_10_1002_adhm_202202609 crossref_primary_10_1158_1078_0432_CCR_17_0432 crossref_primary_10_3389_fimmu_2018_00262 crossref_primary_10_1002_ctm2_992 crossref_primary_10_1016_j_lfs_2020_118005 crossref_primary_10_1038_nrurol_2018_10 crossref_primary_10_1038_s41598_017_12208_7 crossref_primary_10_1039_D1TB00753J crossref_primary_10_18632_aging_205539 crossref_primary_10_1016_j_lfs_2020_118248 crossref_primary_10_1016_j_intimp_2021_108258 crossref_primary_10_1158_2326_6066_CIR_17_0443 crossref_primary_10_1016_j_jneuroim_2022_578009 crossref_primary_10_1039_D3BM00635B crossref_primary_10_3389_fphar_2023_1136960 crossref_primary_10_1038_nrc_2016_73 crossref_primary_10_3389_fcell_2021_764125 crossref_primary_10_1172_JCI155148 crossref_primary_10_1007_s10238_024_01319_x crossref_primary_10_1016_j_smim_2016_03_002 crossref_primary_10_3389_fgene_2022_918705 crossref_primary_10_3390_cancers16091626 crossref_primary_10_4062_biomolther_2021_180 crossref_primary_10_1016_j_jconrel_2016_11_006 crossref_primary_10_1158_1078_0432_CCR_20_4513 crossref_primary_10_1016_j_bbcan_2016_10_003 crossref_primary_10_1093_annonc_mdw534 crossref_primary_10_3389_fimmu_2021_738456 crossref_primary_10_1371_journal_pone_0192157 crossref_primary_10_1021_jacs_2c12772 crossref_primary_10_1084_jem_20190457 crossref_primary_10_37349_etat_2022_00082 crossref_primary_10_1128_mSphere_00467_19 crossref_primary_10_1002_jcb_26005 crossref_primary_10_1016_j_autrev_2024_103529 crossref_primary_10_1016_j_jconrel_2021_11_016 crossref_primary_10_1038_s41423_023_01120_y crossref_primary_10_1080_2162402X_2017_1404214 crossref_primary_10_3389_fimmu_2021_623762 crossref_primary_10_1016_j_bbcan_2020_188416 crossref_primary_10_1002_ijc_31599 crossref_primary_10_3389_fimmu_2022_860041 crossref_primary_10_3390_cancers14010259 crossref_primary_10_1038_s41551_018_0235_9 crossref_primary_10_1016_j_ijpharm_2021_121027 crossref_primary_10_3389_fimmu_2024_1333923 crossref_primary_10_3390_cancers13195011 crossref_primary_10_3390_polym11091441 crossref_primary_10_1186_s13045_018_0579_3 crossref_primary_10_1002_cam4_4531 crossref_primary_10_1038_s41581_018_0032_4 crossref_primary_10_1016_j_canlet_2016_11_027 crossref_primary_10_3389_fimmu_2021_714230 crossref_primary_10_18632_aging_203456 crossref_primary_10_1007_s12312_016_0060_6 crossref_primary_10_1080_14712598_2020_1738378 crossref_primary_10_1080_14712598_2022_2139601 crossref_primary_10_1016_j_omto_2022_01_002 crossref_primary_10_1038_s41389_023_00452_8 crossref_primary_10_3390_cancers13174419 crossref_primary_10_1002_iid3_186 crossref_primary_10_1038_s41568_018_0081_9 crossref_primary_10_1021_acs_jproteome_4c00031 crossref_primary_10_3389_fimmu_2021_739768 crossref_primary_10_12677_ACM_2024_143686 crossref_primary_10_3389_fimmu_2024_1298087 crossref_primary_10_1007_s11051_020_05030_2 crossref_primary_10_1016_j_patol_2018_11_003 crossref_primary_10_2147_JIR_S349186 crossref_primary_10_18632_aging_204630 crossref_primary_10_1016_j_semcdb_2017_12_011 crossref_primary_10_1016_j_smaim_2021_08_004 crossref_primary_10_3389_fimmu_2022_1034516 crossref_primary_10_1007_s00428_020_02930_5 crossref_primary_10_3389_fcell_2022_911811 crossref_primary_10_3389_fphar_2022_995555 crossref_primary_10_1038_s41378_023_00616_x crossref_primary_10_3389_fimmu_2024_1340307 crossref_primary_10_1016_j_biomaterials_2018_02_030 crossref_primary_10_3390_cancers12092687 crossref_primary_10_1002_j_2617_1619_2018_tb00008_x crossref_primary_10_3390_cancers13235998 crossref_primary_10_1002_pmic_201600442 crossref_primary_10_1021_acsnano_3c00764 crossref_primary_10_3389_fimmu_2021_666233 crossref_primary_10_3389_fimmu_2016_00480 crossref_primary_10_3389_fimmu_2018_01679 crossref_primary_10_3390_ijms241914934 crossref_primary_10_1016_j_ebiom_2024_105092 crossref_primary_10_1186_s13045_023_01439_z crossref_primary_10_2174_1386207323666200407075004 crossref_primary_10_1016_j_nantod_2022_101434 crossref_primary_10_1136_jitc_2023_007144 crossref_primary_10_1016_j_actbio_2023_08_007 crossref_primary_10_1016_j_gene_2022_147095 crossref_primary_10_18632_oncotarget_19417 crossref_primary_10_1146_annurev_cancerbio_061421_012235 crossref_primary_10_3389_fonc_2020_00530 crossref_primary_10_1007_s13346_022_01211_9 crossref_primary_10_1021_acs_jmedchem_3c00792 crossref_primary_10_3389_fonc_2022_829777 crossref_primary_10_1007_s12079_022_00682_2 crossref_primary_10_1038_s41598_018_32855_8 crossref_primary_10_1007_s00262_017_2074_z crossref_primary_10_1186_s12935_021_02162_w crossref_primary_10_3389_fimmu_2016_00477 crossref_primary_10_1021_acs_molpharmaceut_2c00424 crossref_primary_10_1186_s13058_023_01684_7 crossref_primary_10_3389_fimmu_2016_00113 crossref_primary_10_1016_j_prp_2023_154789 crossref_primary_10_3389_fgene_2021_814843 crossref_primary_10_1016_j_cej_2022_138210 crossref_primary_10_1016_j_heliyon_2023_e19680 crossref_primary_10_1016_j_nantod_2022_101702 crossref_primary_10_3748_wjg_v22_i23_5317 crossref_primary_10_1186_s12943_018_0814_0 crossref_primary_10_22465_kjuo_2017_15_3_103 crossref_primary_10_3389_fcell_2022_785058 crossref_primary_10_1002_jcla_24135 crossref_primary_10_1016_j_actbio_2022_05_036 crossref_primary_10_1016_j_nantod_2020_101025 crossref_primary_10_1186_s12943_021_01428_1 crossref_primary_10_1016_j_clim_2018_02_013 crossref_primary_10_3389_fcell_2022_818194 crossref_primary_10_3389_fimmu_2023_1165101 crossref_primary_10_1016_j_canlet_2017_01_041 crossref_primary_10_3389_fbioe_2021_744659 crossref_primary_10_3390_cancers14225684 crossref_primary_10_1088_2057_1739_aa7e86 crossref_primary_10_3389_fonc_2023_1091488 crossref_primary_10_3389_fimmu_2023_1340634 crossref_primary_10_2174_1574888X14666181205115452 crossref_primary_10_3389_fbioe_2022_1021966 crossref_primary_10_3389_fimmu_2023_1213629 crossref_primary_10_1155_2022_2930310 crossref_primary_10_3390_genes8090220 crossref_primary_10_1155_2023_1261039 crossref_primary_10_1016_j_jconrel_2021_02_032 crossref_primary_10_3389_fimmu_2019_01394 crossref_primary_10_3389_fgene_2021_642759 crossref_primary_10_1038_s41467_019_10893_8 crossref_primary_10_2174_1567201819666220324093821 crossref_primary_10_1002_ctm2_694 crossref_primary_10_1038_ni_3836 crossref_primary_10_1080_07853890_2023_2200033 crossref_primary_10_15406_jcpcr_2016_06_00216 crossref_primary_10_1016_j_celrep_2017_08_089 crossref_primary_10_1038_s41467_020_19920_5 crossref_primary_10_3389_fcell_2021_676342 crossref_primary_10_3390_jcm12175668 crossref_primary_10_1016_j_ctrv_2017_10_013 crossref_primary_10_3389_fbioe_2023_1277964 crossref_primary_10_1016_j_jim_2017_11_010 crossref_primary_10_18632_oncotarget_17379 crossref_primary_10_3389_fimmu_2022_881722 crossref_primary_10_1007_s12094_022_02940_6 crossref_primary_10_3389_fphar_2018_00006 crossref_primary_10_1021_acsnano_0c06765 crossref_primary_10_1002_advs_202206432 crossref_primary_10_1186_s12885_024_11890_x crossref_primary_10_1155_2023_7059289 crossref_primary_10_3389_fimmu_2023_1212209 crossref_primary_10_1186_s13045_016_0269_y crossref_primary_10_1038_s41585_022_00608_y crossref_primary_10_2217_bmm_2017_0305 crossref_primary_10_3389_fphys_2021_719701 crossref_primary_10_4049_jimmunol_2001203 crossref_primary_10_1016_j_ygeno_2020_12_010 crossref_primary_10_1186_s40425_019_0752_4 crossref_primary_10_3390_cancers12102868 crossref_primary_10_1002_wsbm_1539 crossref_primary_10_3389_fonc_2021_712807 crossref_primary_10_1097_IGC_0000000000001193 crossref_primary_10_1158_0008_5472_CAN_21_3734 crossref_primary_10_3389_fmolb_2021_646786 crossref_primary_10_3389_fimmu_2021_547333 crossref_primary_10_1038_s41590_023_01642_7 crossref_primary_10_1155_2022_5673810 crossref_primary_10_1039_C9BM01083A crossref_primary_10_1038_s41598_022_20566_0 crossref_primary_10_1038_s41467_019_14060_x crossref_primary_10_1093_intimm_dxz012 crossref_primary_10_3389_fimmu_2020_00054 crossref_primary_10_3389_fgene_2022_989081 crossref_primary_10_1111_bph_14351 crossref_primary_10_1002_iid3_608 crossref_primary_10_3389_fonc_2021_753386 crossref_primary_10_1080_08977194_2019_1620227 crossref_primary_10_3389_fgene_2022_870945 crossref_primary_10_3389_fphar_2022_868695 crossref_primary_10_1016_j_jconrel_2019_12_047 crossref_primary_10_1002_adhm_202201233 crossref_primary_10_1016_j_celrep_2023_112475 crossref_primary_10_1155_2022_3924400 crossref_primary_10_1155_2022_5621441 crossref_primary_10_3389_fcell_2021_727935 crossref_primary_10_3390_vaccines4030022 crossref_primary_10_1038_s41568_019_0125_9 crossref_primary_10_34133_research_0282 crossref_primary_10_1007_s00262_023_03368_9 crossref_primary_10_3390_cancers13061466 crossref_primary_10_1155_2023_9946911 crossref_primary_10_1186_s40537_022_00641_z crossref_primary_10_1016_j_ymthe_2021_08_023 crossref_primary_10_1016_j_heliyon_2024_e28356 crossref_primary_10_1186_s12989_016_0158_0 crossref_primary_10_1177_02611929231193421 crossref_primary_10_1186_s12943_023_01748_4 crossref_primary_10_3389_fcell_2022_821678 crossref_primary_10_1007_s10495_023_01879_5 crossref_primary_10_1016_j_imlet_2016_06_002 crossref_primary_10_1016_j_biomaterials_2019_119469 crossref_primary_10_1016_j_pan_2023_10_008 crossref_primary_10_1016_j_clbc_2020_04_009 crossref_primary_10_1016_j_intimp_2022_109660 crossref_primary_10_1080_2162402X_2021_1987636 crossref_primary_10_3390_nano8020067 crossref_primary_10_3390_cancers14143326 crossref_primary_10_3389_fimmu_2020_609337 crossref_primary_10_3389_fcell_2021_754069 crossref_primary_10_1152_physiolgenomics_00023_2016 crossref_primary_10_1016_j_bbadis_2024_167304 crossref_primary_10_1016_j_cej_2024_152032 crossref_primary_10_1186_s12859_023_05399_6 crossref_primary_10_2147_OTT_S447319 crossref_primary_10_1016_j_semcancer_2018_01_005 crossref_primary_10_3389_fgene_2022_975190 crossref_primary_10_3748_wjg_v24_i20_2137 crossref_primary_10_1021_acs_molpharmaceut_8b01317 crossref_primary_10_4251_wjgo_v16_i3_919 crossref_primary_10_1080_10428194_2022_2064995 crossref_primary_10_26508_lsa_201800079 crossref_primary_10_1016_j_omtm_2020_01_005 crossref_primary_10_18632_aging_205231 crossref_primary_10_3390_vaccines11010059 crossref_primary_10_1016_j_bbcan_2022_188829 crossref_primary_10_1097_MEG_0000000000002756 crossref_primary_10_3390_cancers14143315 crossref_primary_10_1007_s11684_020_0746_0 crossref_primary_10_1007_s12672_022_00487_0 crossref_primary_10_3389_fonc_2023_1183059 crossref_primary_10_2147_OTT_S247836 crossref_primary_10_1111_cas_14616 crossref_primary_10_1038_nrc_2017_17 crossref_primary_10_2147_OTT_S305098 crossref_primary_10_1016_j_celrep_2023_113494 crossref_primary_10_3389_fgene_2021_787208 crossref_primary_10_1016_j_ijbiomac_2023_123664 crossref_primary_10_1016_j_actbio_2019_05_052 crossref_primary_10_18632_oncotarget_21575 crossref_primary_10_1242_dev_155861 crossref_primary_10_1002_cac2_12452 crossref_primary_10_1186_s12885_018_5035_9 crossref_primary_10_3389_fimmu_2022_1071636 crossref_primary_10_1038_s41586_020_2424_4 crossref_primary_10_1007_s00432_023_05011_7 crossref_primary_10_1155_2016_7803091 crossref_primary_10_1016_j_coisb_2017_01_006 crossref_primary_10_1016_j_pharmthera_2019_04_004 crossref_primary_10_3389_fmolb_2019_00160 crossref_primary_10_1007_s11427_020_1811_5 crossref_primary_10_1016_j_jconrel_2022_04_013 crossref_primary_10_1186_s12967_021_03112_w crossref_primary_10_1007_s12015_023_10593_3 crossref_primary_10_1016_j_semcancer_2022_02_006 crossref_primary_10_1016_j_ccell_2023_06_005 crossref_primary_10_1016_j_ccell_2023_06_008 crossref_primary_10_1016_j_biosx_2024_100499 crossref_primary_10_1038_s42255_020_0174_0 crossref_primary_10_1016_j_jocn_2017_08_050 crossref_primary_10_3389_fonc_2020_591739 crossref_primary_10_3892_ijmm_2019_4418 crossref_primary_10_1158_2326_6066_CIR_19_0311 crossref_primary_10_1002_mc_23445 crossref_primary_10_1155_2022_7406636 crossref_primary_10_1021_acs_jmedchem_3c00946 crossref_primary_10_2217_imt_2016_0125 crossref_primary_10_1016_j_canlet_2016_01_043 crossref_primary_10_3389_fimmu_2022_994259 crossref_primary_10_3389_fmolb_2023_1297611 crossref_primary_10_1080_2162402X_2017_1371896 crossref_primary_10_1155_2022_5983629 crossref_primary_10_1155_2022_8580043 crossref_primary_10_3390_ijms20184624 crossref_primary_10_1080_2162402X_2020_1824641 crossref_primary_10_1186_s13046_019_1515_2 crossref_primary_10_1080_2162402X_2020_1747350 crossref_primary_10_1093_nar_gkaa805 crossref_primary_10_1080_2162402X_2020_1824643 crossref_primary_10_1007_s11427_019_1569_4 crossref_primary_10_1002_ddr_22185 crossref_primary_10_1007_s44164_023_00043_2 crossref_primary_10_3390_cancers13215382 crossref_primary_10_1038_labinvest_2017_25 crossref_primary_10_1111_cas_15057 crossref_primary_10_3389_fcell_2021_658984 crossref_primary_10_1021_acsnano_2c08834 crossref_primary_10_1016_j_mtbio_2023_100821 crossref_primary_10_1038_s41698_022_00292_6 crossref_primary_10_1186_s12935_024_03218_3 crossref_primary_10_1002_adhm_201701165 crossref_primary_10_3389_fendo_2022_988295 crossref_primary_10_1038_s41575_019_0115_0 crossref_primary_10_3389_fgene_2022_857215 crossref_primary_10_1016_j_cmet_2019_01_015 crossref_primary_10_3389_fgene_2021_723796 crossref_primary_10_1038_s41598_023_41343_7 crossref_primary_10_1186_s13036_023_00352_w crossref_primary_10_1158_2326_6066_CIR_22_0593 crossref_primary_10_1155_2019_2408348 crossref_primary_10_1016_j_canlet_2019_06_017 crossref_primary_10_1186_s10020_020_00174_2 crossref_primary_10_3389_fimmu_2022_934083 crossref_primary_10_1681_ASN_2020020220 crossref_primary_10_3390_ijms241914799 crossref_primary_10_1038_s41467_023_40850_5 crossref_primary_10_1016_j_biopha_2023_115622 crossref_primary_10_1016_j_drudis_2017_03_011 crossref_primary_10_1158_0008_5472_CAN_19_2888 crossref_primary_10_1186_s40478_020_01096_0 crossref_primary_10_3389_fimmu_2022_905057 crossref_primary_10_1182_blood_2016_08_737239 crossref_primary_10_1002_jcp_30419 crossref_primary_10_1016_j_cej_2022_136322 crossref_primary_10_1016_j_cmet_2017_08_014 crossref_primary_10_1186_s12931_022_02108_4 crossref_primary_10_1016_j_semcancer_2018_02_005 crossref_primary_10_1089_ten_tea_2023_29046_abstracts crossref_primary_10_1039_C7NR05316A crossref_primary_10_1189_jlb_5VMR1116_493R crossref_primary_10_1016_j_abb_2020_108659 crossref_primary_10_1016_j_bbcan_2019_06_003 crossref_primary_10_1002_advs_202001447 crossref_primary_10_2147_IJN_S460387 crossref_primary_10_1186_s13059_017_1349_1 crossref_primary_10_1002_adma_202110614 crossref_primary_10_1038_s12276_023_01114_w crossref_primary_10_1038_s41556_019_0346_x crossref_primary_10_1016_j_nantod_2017_06_010 crossref_primary_10_3389_fmed_2022_897750 crossref_primary_10_1007_s12672_021_00442_5 crossref_primary_10_3390_cancers15102774 crossref_primary_10_3390_cancers11030310 crossref_primary_10_1016_j_bbcan_2020_188390 crossref_primary_10_1002_smll_202306303 crossref_primary_10_1186_s40478_023_01605_x crossref_primary_10_3390_cells11091590 crossref_primary_10_1016_j_apsb_2021_05_016 crossref_primary_10_3389_fcell_2021_729941 crossref_primary_10_3390_vaccines4040041 crossref_primary_10_17749_2313_7347_ob_gyn_rep_2024_489 crossref_primary_10_1111_cpr_12865 crossref_primary_10_18632_oncotarget_27915 crossref_primary_10_3390_cancers15030610 crossref_primary_10_1016_j_cca_2018_09_027 crossref_primary_10_1038_s41571_020_0403_1 crossref_primary_10_1002_adfm_201804492 crossref_primary_10_1038_s41467_018_02892_y crossref_primary_10_1155_2021_1589864 crossref_primary_10_3389_fonc_2022_861959 crossref_primary_10_3389_fonc_2023_1333839 crossref_primary_10_2147_IJGM_S343046 crossref_primary_10_3727_096504020X15907428281601 crossref_primary_10_1159_000538456 crossref_primary_10_1016_j_bioactmat_2021_02_037 crossref_primary_10_1002_path_5357 crossref_primary_10_1038_s41598_021_90330_3 crossref_primary_10_1016_j_tranon_2023_101866 crossref_primary_10_1039_D1TB00397F crossref_primary_10_3389_fbioe_2021_784602 crossref_primary_10_1039_C9NR07947E crossref_primary_10_1002_adma_202211509 crossref_primary_10_3389_fimmu_2021_722479 crossref_primary_10_3389_fphar_2024_1338471 crossref_primary_10_1111_jcmm_18208 crossref_primary_10_3390_ijms232314770 crossref_primary_10_1136_jitc_2022_006472 crossref_primary_10_1136_jitc_2023_006770 crossref_primary_10_1016_j_jff_2023_105638 crossref_primary_10_1186_s12943_020_01170_0 crossref_primary_10_1038_s41598_020_68074_3 crossref_primary_10_1158_1078_0432_CCR_17_3262 crossref_primary_10_1007_s12031_020_01484_0 crossref_primary_10_1126_scitranslmed_adj5705 crossref_primary_10_1016_j_csbj_2022_06_046 crossref_primary_10_3389_fimmu_2024_1335774 crossref_primary_10_1016_j_biomaterials_2020_120190 crossref_primary_10_1021_acs_molpharmaceut_2c00629 crossref_primary_10_1016_j_csbj_2016_10_005 crossref_primary_10_1016_j_bbamcr_2024_119698 crossref_primary_10_1016_j_apsb_2017_12_001 crossref_primary_10_1038_s41419_021_03853_y crossref_primary_10_1002_adma_201601902 crossref_primary_10_2174_156802661917190828111130 crossref_primary_10_1158_0008_5472_CAN_18_0912 crossref_primary_10_18632_aging_205189 crossref_primary_10_3389_fonc_2023_1257266 crossref_primary_10_1016_j_slasd_2023_03_006 crossref_primary_10_1021_acs_chemrev_7b00534 crossref_primary_10_1186_s12935_020_01540_0 crossref_primary_10_3389_fonc_2024_1402483 crossref_primary_10_1155_2023_2311231 crossref_primary_10_1002_adfm_201805760 crossref_primary_10_1007_s00262_022_03290_6 crossref_primary_10_1155_2017_8482326 crossref_primary_10_3390_ijms23158489 crossref_primary_10_1186_s12885_022_10491_w crossref_primary_10_1002_adma_202008094 crossref_primary_10_3389_fimmu_2023_1097880 crossref_primary_10_3389_fcell_2018_00098 crossref_primary_10_1155_2021_9989790 crossref_primary_10_1038_s41568_020_0245_2 crossref_primary_10_1021_acsbiomaterials_6b00246 crossref_primary_10_1080_2162402X_2020_1832347 crossref_primary_10_1002_adma_201803001 crossref_primary_10_1097_MD_0000000000038173 crossref_primary_10_1155_2021_9987376 crossref_primary_10_1016_j_heliyon_2023_e16027 crossref_primary_10_1158_1078_0432_CCR_18_0420 crossref_primary_10_1016_S0007_4551_16_30146_1 crossref_primary_10_1515_nanoph_2021_0390 crossref_primary_10_1021_acsnano_1c07504 crossref_primary_10_1186_s13045_019_0770_1 crossref_primary_10_3389_fimmu_2022_971278 crossref_primary_10_3389_fphar_2024_1387647 crossref_primary_10_1039_c9mt00051h crossref_primary_10_1136_jitc_2019_000205 crossref_primary_10_1002_mc_23150 crossref_primary_10_1136_jitc_2019_000444 crossref_primary_10_3390_biom9090429 crossref_primary_10_1002_anbr_202300056 crossref_primary_10_1021_acsnano_3c13056 crossref_primary_10_2174_1871520620999200730161829 crossref_primary_10_2217_imt_2022_0175 crossref_primary_10_1016_j_isci_2023_106616 crossref_primary_10_1039_C7NR08747K crossref_primary_10_1039_D0NJ05169A crossref_primary_10_3389_fimmu_2021_702726 crossref_primary_10_1002_hep_30676 crossref_primary_10_1002_jcp_29842 crossref_primary_10_3389_fcell_2021_786728 crossref_primary_10_1016_j_coi_2018_03_014 crossref_primary_10_3389_fonc_2022_881871 crossref_primary_10_3389_fcell_2019_00052 crossref_primary_10_2217_fon_2015_0039 crossref_primary_10_1016_j_biopha_2019_109461 crossref_primary_10_1002_cam4_1722 crossref_primary_10_1186_s13045_019_0826_2 crossref_primary_10_4062_biomolther_2023_005 crossref_primary_10_1038_s41388_018_0160_0 crossref_primary_10_1016_j_gendis_2020_01_016 crossref_primary_10_1158_2326_6066_CIR_22_0290 crossref_primary_10_1158_2159_8290_CD_22_0876 crossref_primary_10_1016_j_cell_2019_08_008 crossref_primary_10_1016_j_biomaterials_2020_120275 crossref_primary_10_1080_2162402X_2018_1548241 crossref_primary_10_1038_s41598_022_13499_1 crossref_primary_10_1016_j_celrep_2022_110639 crossref_primary_10_3389_fonc_2019_01135 crossref_primary_10_1016_j_ctro_2020_04_001 crossref_primary_10_3390_cancers13133248 crossref_primary_10_1016_j_cellimm_2021_104436
Cites_doi	10.1038/nature06868 10.1038/nrc3581 10.1002/hep.24352 10.1073/pnas.1011748107 10.1158/1078-0432.CCR-08-1332 10.1016/j.mvr.2011.01.006 10.1007/s00418-009-0661-6 10.1038/nm.3833 10.1172/JCI200318549 10.1172/JCI26532 10.1158/0008-5472.CAN-11-1301 10.1038/nm.3541 10.1242/jcs.02605 10.1016/j.humimm.2009.01.014 10.1093/jnci/djm064 10.1007/s00262-009-0747-y 10.1159/000012021 10.1038/nrc1477 10.2174/156800906778742460 10.1038/nature14011 10.4049/jimmunol.174.9.5215 10.1186/1472-6890-14-38 10.1182/blood-2004-03-1109 10.1038/nrc1877 10.1089/scd.2013.0084 10.1016/j.immuni.2013.07.012 10.1158/0008-5472.CAN-14-0079 10.1084/jem.20090397 10.1016/j.tig.2008.10.012 10.1084/jem.185.1.1 10.1038/ncomms3516 10.1016/j.ccr.2007.04.017 10.1083/jcb.200704042 10.1136/gutjnl-2012-302529 10.1016/j.ccr.2014.04.021 10.1038/ncomms8114 10.1002/ijc.10481 10.1038/nm.2848 10.1158/0008-5472.CAN-11-0431 10.1038/sj.icb.7100116 10.1111/j.1582-4934.2010.01044.x 10.1158/0008-5472.CAN-08-0287 10.1126/science.1195300 10.1038/nri1418 10.1111/j.1582-4934.2010.01215.x 10.1101/cshperspect.a006494 10.1038/nature11183 10.1002/ijc.25920 10.1182/blood-2008-04-151753 10.4049/jimmunol.1002961 10.1146/annurev.pathol.2.010506.134925 10.1016/j.devcel.2011.04.019 10.4049/jimmunol.0803974 10.1073/pnas.1113873109 10.1084/jem.190.8.1175 10.1073/pnas.0601807103 10.1016/j.ccr.2005.02.013 10.1016/j.cell.2009.10.027 10.1172/JCI31178 10.4161/cbt.5.12.3354 10.1016/j.celrep.2012.01.005 10.4049/jimmunol.169.7.3581 10.1073/pnas.1416498111 10.1038/ncomms4989 10.1038/ni831 10.4049/jimmunol.1300280 10.4049/jimmunol.167.5.2459 10.1038/nm0603-685 10.4049/jimmunol.177.5.3082 10.1038/nri2414 10.1126/science.1232227 10.4049/jimmunol.164.6.2947 10.1161/CIRCRESAHA.108.176826 10.1073/pnas.86.19.7437 10.1084/jem.20092465 10.1002/path.1543 10.4049/jimmunol.178.3.1505 10.1016/j.ccr.2004.08.031 10.1073/pnas.0906481106 10.1161/ATVBAHA.107.158451 10.1164/rccm.201309-1611OC 10.1158/1078-0432.CCR-06-1746 10.1016/j.ccr.2014.04.005 10.1158/2326-6066.CIR-13-0027 10.1016/j.jaut.2009.08.008 10.1016/j.immuni.2014.06.010 10.1172/JCI45817 10.1111/imr.12023 10.1038/modpathol.2010.95 10.1016/j.ccr.2007.04.020 10.1158/0008-5472.CAN-12-1377 10.1002/eji.200324270 10.1126/science.1198443 10.1158/1078-0432.CCR-11-3114 10.1038/nri3846 10.1038/nature14395 10.1084/jem.20021378 10.1038/labinvest.2013.139 10.1038/nature07424 10.1007/s00441-003-0745-x 10.1182/blood-2003-04-1193 10.1007/s12032-013-0663-z 10.1111/j.1398-9995.2003.00442.x 10.1038/35036374 10.1152/physrev.00038.2010 10.1038/nrc2618 10.1016/j.bbrc.2012.05.081 10.1016/j.ccr.2012.01.007 10.1002/ijc.2910420110 10.1007/s10911-010-9193-x 10.1038/nri1151 10.1016/j.ccr.2005.01.017 10.1038/nature06348 10.1158/1078-0432.CCR-06-2191 10.1158/1078-0432.CCR-11-2188 10.1097/CJI.0b013e3181f4c208 10.1038/ni749 10.1073/pnas.0705673104 10.4049/jimmunol.164.4.2193 10.1038/nm1699 10.1158/0008-5472.CAN-06-1278 10.1038/nature03096 10.1101/cshperspect.a005058 10.1016/j.jneuroim.2013.09.011 10.1007/s00018-013-1339-8 10.1073/pnas.1320318110 10.1038/nature08782 10.1182/blood.V88.2.667.bloodjournal882667 10.1371/journal.pone.0007965 10.1038/nature09707 10.4161/onci.26836 10.1002/(SICI)1521-4141(199905)29:05<1435::AID-IMMU1435>3.0.CO;2-N 10.1016/j.ccr.2012.02.017 10.1038/nm1649 10.1038/nature13954 10.1007/s00262-003-0445-0 10.1038/nature13904 10.1038/nri3700 10.1038/nrc3186 10.1084/jem.20101876 10.1083/jcb.200109098 10.1182/blood.V92.12.4778.424k14_4778_4791 10.4049/jimmunol.1003917 10.1101/gad.13.11.1382
ContentType	Journal Article
Copyright	Springer Nature Limited 2015 COPYRIGHT 2015 Nature Publishing Group Copyright Nature Publishing Group Nov 2015
Copyright_xml	– notice: Springer Nature Limited 2015 – notice: COPYRIGHT 2015 Nature Publishing Group – notice: Copyright Nature Publishing Group Nov 2015
DBID	CGR CUY CVF ECM EIF NPM AAYXX CITATION ISR 3V. 7QR 7RV 7T5 7U9 7X7 7XB 88E 8AO 8C1 8FD 8FE 8FH 8FI 8FJ 8FK ABUWG AFKRA AZQEC BBNVY BENPR BHPHI CCPQU DWQXO FR3 FYUFA GHDGH GNUQQ H94 HCIFZ K9. KB0 LK8 M0S M1P M7N M7P NAPCQ P64 PQEST PQQKQ PQUKI 7X8
DOI	10.1038/nri3902
DatabaseName	Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef Gale in Context: Science ProQuest Central (Corporate) Chemoreception Abstracts Nursing & Allied Health Database Immunology Abstracts Virology and AIDS Abstracts ProQuest_Health & Medical Collection ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) ProQuest Pharma Collection Public Health Database Technology Research Database ProQuest SciTech Collection ProQuest Natural Science Collection Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Central (Alumni) ProQuest Central ProQuest Central Essentials Biological Science Collection ProQuest Central Natural Science Collection ProQuest One Community College ProQuest Central Engineering Research Database Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student AIDS and Cancer Research Abstracts SciTech Premium Collection (Proquest) (PQ_SDU_P3) ProQuest Health & Medical Complete (Alumni) Nursing & Allied Health Database (Alumni Edition) ProQuest Biological Science Collection Health & Medical Collection (Alumni Edition) PML(ProQuest Medical Library) Algology Mycology and Protozoology Abstracts (Microbiology C) Biological Science Database Nursing & Allied Health Premium Biotechnology and BioEngineering Abstracts ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic ProQuest One Academic UKI Edition MEDLINE - Academic
DatabaseTitle	MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef ProQuest Central Student Technology Research Database ProQuest Central Essentials ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) SciTech Premium Collection ProQuest One Community College ProQuest Natural Science Collection ProQuest Pharma Collection ProQuest Central Health Research Premium Collection Health and Medicine Complete (Alumni Edition) Natural Science Collection ProQuest Central Korea Algology Mycology and Protozoology Abstracts (Microbiology C) Biological Science Collection AIDS and Cancer Research Abstracts Chemoreception Abstracts ProQuest Medical Library (Alumni) ProQuest Public Health Virology and AIDS Abstracts ProQuest Biological Science Collection ProQuest One Academic Eastern Edition ProQuest Nursing & Allied Health Source ProQuest Hospital Collection Health Research Premium Collection (Alumni) Biological Science Database ProQuest SciTech Collection ProQuest Hospital Collection (Alumni) Biotechnology and BioEngineering Abstracts Nursing & Allied Health Premium ProQuest Health & Medical Complete ProQuest Medical Library ProQuest One Academic UKI Edition Immunology Abstracts ProQuest Nursing & Allied Health Source (Alumni) Engineering Research Database ProQuest One Academic ProQuest Central (Alumni) MEDLINE - Academic
DatabaseTitleList	MEDLINE MEDLINE - Academic AIDS and Cancer Research Abstracts ProQuest Central Student
Database_xml	– sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database – sequence: 3 dbid: BENPR name: ProQuest Central url: https://www.proquest.com/central sourceTypes: Aggregation Database
DeliveryMethod	fulltext_linktorsrc
Discipline	Medicine Biology
EISSN	1474-1741
EndPage	682
ExternalDocumentID	3960561771 A433483208 10_1038_nri3902 26471778
Genre	Journal Article Review
GeographicLocations	United States United States--US Massachusetts
GeographicLocations_xml	– name: United States – name: United States--US – name: Massachusetts
GroupedDBID	--- .55 0R~ 123 29M 36B 39C 3V. 4.4 53G 70F 7RV 7X7 88E 8AO 8C1 8FE 8FH 8FI 8FJ 8R4 8R5 AAEEF AARCD AAWYQ AAZLF ABAWZ ABDBF ABJNI ABLJU ABUWG ABVXF ACGFS ACIWK ACPRK ADBBV AENEX AFBBN AFKRA AFRAH AFSHS AGAYW AGEZK AGHTU AHBCP AHMBA AHOSX AHSBF AIBTJ AIYXT ALFFA ALIPV ALMA_UNASSIGNED_HOLDINGS ARMCB ASPBG AVWKF AXYYD AZFZN B0M BBNVY BENPR BHPHI BKEYQ BKKNO BPHCQ BVXVI CCPQU CS3 DB5 DU5 EAD EAP EBC EBD EBS EE. EJD EMB EMK EMOBN EPL ESX EX3 EXGXG F5P FEDTE FQGFK FSGXE FYUFA HCIFZ HMCUK HVGLF HZ~ IAO IHR IHW INH INR ISR ITC L-9 LK8 M1P M7P N9A NAPCQ NNMJJ O9- ODYON P2P PQQKQ PROAC PSQYO Q2X RNR RNT RNTTT SHXYY SIXXV SNYQT SV3 TAOOD TBHMF TDRGL TSG TUS UKHRP WOW X7M ~8M AAYZH CGR CUY CVF ECM EIF NPM AAYXX CITATION AAEXX ABEEJ ADZGE AADEA AADWK AAJMP AAYJO ABGIJ ACBMV ACBRV ACBYP ACIGE ACTTH ACVWB ADMDM ADQMX AEDAW AEFTE AGGBP AGPPL AHGBK AJDOV NYICJ ZA5 7QR 7T5 7U9 7XB 8FD 8FK AZQEC DWQXO FR3 GNUQQ H94 K9. M7N P64 PQEST PQUKI 7X8
ID	FETCH-LOGICAL-c577t-17a7f1f1a929c495e5053463f82000d550f8c56bb0873805121ca33d7d699f333
IEDL.DBID	BENPR
ISSN	1474-1733
IngestDate	Fri Aug 16 23:19:51 EDT 2024 Sat Aug 17 00:34:14 EDT 2024 Thu Oct 10 21:03:20 EDT 2024 Thu Feb 22 23:46:59 EST 2024 Fri Feb 02 04:28:04 EST 2024 Thu Aug 01 19:18:56 EDT 2024 Tue Aug 20 22:00:13 EDT 2024 Thu Sep 12 18:31:30 EDT 2024 Tue Oct 15 23:55:46 EDT 2024 Fri Oct 11 20:45:42 EDT 2024
IsPeerReviewed	true
IsScholarly	true
Issue	11
Language	English
LinkModel	DirectLink
MergedId	FETCHMERGED-LOGICAL-c577t-17a7f1f1a929c495e5053463f82000d550f8c56bb0873805121ca33d7d699f333
Notes	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 ObjectType-Article-1 ObjectType-Feature-2
PMID	26471778
PQID	1767343691
PQPubID	27582
PageCount	14
ParticipantIDs	proquest_miscellaneous_1773830081 proquest_miscellaneous_1727435656 proquest_journals_1767343691 gale_infotracmisc_A433483208 gale_infotracacademiconefile_A433483208 gale_incontextgauss_ISR_A433483208 gale_healthsolutions_A433483208 crossref_primary_10_1038_nri3902 pubmed_primary_26471778 springer_journals_10_1038_nri3902
PublicationCentury	2000
PublicationDate	2015-11-01
PublicationDateYYYYMMDD	2015-11-01
PublicationDate_xml	– month: 11 year: 2015 text: 2015-11-01 day: 01
PublicationDecade	2010
PublicationPlace	London
PublicationPlace_xml	– name: London – name: England
PublicationTitle	Nature reviews. Immunology
PublicationTitleAbbrev	Nat Rev Immunol
PublicationTitleAlternate	Nat Rev Immunol
PublicationYear	2015
Publisher	Nature Publishing Group UK Nature Publishing Group
Publisher_xml	– name: Nature Publishing Group UK – name: Nature Publishing Group
References	Levental (CR132) 2009; 139 Salmon (CR33) 2012; 122 Mulligan, Day, Gillespie, Rosenzweig, Young (CR49) 2009; 70 Shalapour (CR31) 2015; 521 Olson, Soriano (CR66) 2011; 20 Balsamo (CR78) 2009; 106 Ruegg, Chiquet-Ehrismann, Alkan (CR87) 1989; 86 Ko (CR119) 2009; 15 Starkey, Crowle, Taubenberger (CR106) 1988; 42 Swartz, Lund (CR57) 2012; 12 Saunier, Akhurst (CR74) 2006; 6 Feig (CR128) 2012; 18 Junt, Scandella, Ludewig (CR139) 2008; 8 Fletcher, Acton, Knoblich (CR138) 2015; 15 Provenzano (CR34) 2012; 21 Tamburini, Burchill, Kedl (CR56) 2014; 5 Maciag, Seavey, Pan, Ferrone, Paterson (CR126) 2008; 68 Liao, Luo, Markowitz, Xiang, Reisfeld (CR26) 2009; 4 Textor (CR116) 2014; 74 Wipff, Rifkin, Meister, Hinz (CR59) 2007; 179 Gerhardt, Betsholtz (CR125) 2003; 314 Takanami, Takeuchi, Kodaira (CR98) 1999; 57 Valujskikh, Lantz, Celli, Matzinger, Heeger (CR39) 2002; 3 Avice, Rubio, Sergerie, Delespesse, Sarfati (CR92) 2001; 167 Parks, Wilson, Lopez-Boado (CR94) 2004; 4 Sugimoto, Mundel, Kieran, Kalluri (CR121) 2006; 5 Malhotra, Fletcher, Turley (CR140) 2013; 251 Herbst (CR7) 2014; 515 Hamzah (CR14) 2008; 453 Huang (CR44) 2010; 207 Pilotte (CR53) 2012; 109 Paunescu (CR81) 2011; 15 Peske (CR146) 2015; 6 Furuya (CR13) 2004; 203 Lund (CR54) 2012; 1 Cohen (CR55) 2010; 207 Achen, McColl, Stacker (CR117) 2005; 7 Demeure (CR89) 2000; 164 Bhowmick, Neilson, Moses (CR129) 2004; 432 Ammirante, Luo, Grivennikov, Nedospasov, Karin (CR114) 2010; 464 Peranzoni, Rivas-Caicedo, Bougherara, Salmon, Donnadieu (CR135) 2013; 70 Caruana (CR36) 2015; 21 Broderick, Bankert (CR76) 2006; 177 Cipponi (CR148) 2012; 72 Mueller, Fusenig (CR120) 2004; 4 Ma (CR46) 2010; 107 Byrne, Knox, Halliday (CR77) 2008; 86 Li (CR93) 2002; 157 Coussens (CR104) 1999; 13 Goel (CR15) 2011; 91 Yang (CR103) 2004; 6 Kim (CR82) 2012; 423 Schenkel, Mamdouh, Chen, Liebman, Muller (CR23) 2002; 3 Gommerman, Browning (CR115) 2003; 3 Munn, Mellor (CR52) 2007; 117 Strnad (CR130) 2010; 133 Nozawa, Chiu, Hanahan (CR100) 2006; 103 Dulauroy, Di Carlo, Langa, Eberl, Peduto (CR69) 2012; 18 Germain (CR145) 2014; 189 Djouad (CR70) 2003; 102 Balkwill, Charles, Mantovani (CR109) 2005; 7 Tan (CR28) 2011; 470 Leek (CR96) 1996; 56 Wang (CR85) 2014; 2 Onita (CR97) 2002; 8 Mulligan, Young (CR50) 2010; 59 Noy, Pollard (CR111) 2014; 41 Savinov, Wong, Stonebraker, Chervonsky (CR40) 2003; 197 Shetty (CR21) 2011; 186 Pivarcsi (CR5) 2007; 104 Zhao (CR64) 2011; 129 Tsujino (CR123) 2007; 13 Castermans, Griffioen (CR9) 2007; 1776 Zumsteg, Christofori (CR108) 2012; 2 Ammirante, Shalapour, Kang, Jamieson, Karin (CR30) 2014; 111 Montesinos (CR71) 2013; 22 Powles (CR6) 2014; 515 Mazanet, Hughes (CR43) 2002; 169 Chen, Mellman (CR4) 2013; 39 Ichikawa, Mucida, Tyznik, Kronenberg, Cheroutre (CR62) 2011; 186 Coussens, Zitvogel, Palucka (CR95) 2013; 339 Ahmadzadeh, Rosenberg (CR75) 2005; 174 Armant (CR88) 1999; 190 Shields (CR133) 2007; 11 Secchiero, Zauli (CR47) 2008; 28 Griffioen, Damen, Blijham, Groenewegen (CR16) 1996; 88 Feig (CR29) 2013; 110 Gnecchi, Zhang, Ni, Dzau (CR73) 2008; 103 Lu, Takai, Weaver, Werb (CR110) 2011; 3 Bouzin, Brouet, De Vriese, Dewever, Feron (CR18) 2007; 178 Chauhan (CR134) 2013; 4 Joyce, Pollard (CR1) 2009; 9 Zang (CR41) 2010; 23 Kraman (CR84) 2010; 330 Bergers (CR101) 2000; 2 Tumeh (CR8) 2014; 515 Terabe, Park, Berzofsky (CR113) 2004; 53 Henry (CR122) 2007; 13 Bose (CR68) 2013; 191 Motz (CR48) 2014; 20 Casos (CR51) 2011; 81 Griffioen, Damen, Martinotti, Blijham, Groenewegen (CR17) 1996; 56 Greenberg (CR12) 2008; 456 Nagy, Dvorak, Dvorak (CR10) 2007; 2 Jain (CR11) 2003; 9 Menetrier-Caux (CR83) 1998; 92 Beatty (CR112) 2011; 331 Vallejo, Mugge, Klimiuk, Weyand, Goronzy (CR91) 2000; 164 Steg (CR137) 2012; 18 Pitzalis, Jones, Bombardieri, Jones (CR142) 2014; 14 De Monte (CR80) 2011; 208 Kalluri, Zeisberg (CR32) 2006; 6 Wirsing, Rikardsen, Steigen, Uhlin-Hansen, Hadler-Olsen (CR144) 2014; 14 Abramsson, Lindblom, Betsholtz (CR124) 2003; 112 Seaman (CR45) 2007; 11 Han (CR72) 2011; 15 Talmadge, Gabrilovich (CR24) 2013; 13 Peduto (CR141) 2009; 182 Rodig (CR42) 2003; 33 Soucek (CR105) 2007; 13 Polyak, Haviv, Campbell (CR2) 2009; 25 Ahamed (CR60) 2008; 112 Goc, Fridman, Sautes-Fridman, Dieu-Nosjean (CR143) 2013; 2 Loeffler, Kruger, Niethammer, Reisfeld (CR25) 2006; 116 Li (CR79) 2013; 30 Schildberg (CR63) 2011; 54 Nummer (CR22) 2007; 99 Jacobetz (CR35) 2013; 62 Tiegs, Lohse (CR61) 2010; 34 Adotevi (CR118) 2010; 33 Lund, Swartz (CR127) 2010; 15 Munitz, Levi-Schaffer (CR107) 2004; 59 Reinhold, Lindberg, Kersh, Allen, Brown (CR90) 1997; 185 Rhim (CR38) 2014; 25 Ozdemir (CR37) 2014; 25 Ng, Hinz, Swartz (CR58) 2005; 118 LeBedis, Chen, Fallavollita, Boutros, Brodt (CR131) 2002; 100 Buckanovich (CR19) 2008; 14 Murdoch, Giannoudis, Lewis (CR27) 2004; 104 Shojaei (CR102) 2007; 450 Hauzenberger, Olivier, Gundersen, Ruegg (CR86) 1999; 29 Martinet (CR147) 2011; 71 Lin (CR99) 2006; 66 Straussman (CR136) 2012; 487 Delfortrie (CR20) 2011; 71 Zhao (CR65) 2014; 94 Nakasone (CR3) 2012; 21 Ochs (CR67) 2013; 265 25428505 - Nature. 2014 Nov 27;515(7528):568-71 14610620 - Cancer Immunol Immunother. 2004 Feb;53(2):79-85 19380827 - J Immunol. 2009 May 1;182(9):5789-99 21091630 - J Cell Mol Med. 2011 Nov;15(11):2343-52 10359097 - Eur J Immunol. 1999 May;29(5):1435-47 19956757 - PLoS One. 2009 Nov 23;4(11):e7965 17652277 - J Natl Cancer Inst. 2007 Aug 1;99(15):1188-99 22142828 - Clin Cancer Res. 2012 Feb 1;18(3):869-81 18997771 - Nature. 2008 Dec 11;456(7223):809-13 24484236 - Am J Respir Crit Care Med. 2014 Apr 1;189(7):832-44 25428503 - Nature. 2014 Nov 27;515(7528):558-62 21664579 - Dev Cell. 2011 Jun 14;20(6):815-26 25924065 - Nature. 2015 May 7;521(7550):94-8 19934056 - Proc Natl Acad Sci U S A. 2009 Dec 8;106(49):20847-52 8996237 - J Exp Med. 1997 Jan 6;185(1):1-11 22832193 - Cell Rep. 2012 Mar 29;1(3):191-9 23656504 - Stem Cells Dev. 2013 Sep 15;22(18):2508-19 21339327 - J Exp Med. 2011 Mar 14;208(3):469-78 12778167 - Nat Med. 2003 Jun;9(6):685-93 15516957 - Nat Rev Cancer. 2004 Nov;4(11):839-49 23278748 - Immunol Rev. 2013 Jan;251(1):160-76 24856586 - Cancer Cell. 2014 Jun 16;25(6):719-34 15710325 - Cancer Cell. 2005 Feb;7(2):121-7 18157142 - Nat Med. 2008 Jan;14(1):28-36 24948366 - Nat Rev Immunol. 2014 Jul;14(7):447-62 15095478 - J Pathol. 2004 May;203(1):551-8 18418378 - Nature. 2008 May 15;453(7193):410-4 20835756 - J Mammary Gland Biol Neoplasia. 2010 Sep;15(3):341-52 20308365 - J Exp Med. 2010 Apr 12;207(4):681-8 22037871 - Cancer Res. 2011 Dec 1;71(23):7176-86 25297631 - Cancer Res. 2014 Dec 1;74(23):6796-805 18544680 - Blood. 2008 Nov 1;112(9):3650-60 22439937 - Cancer Cell. 2012 Mar 20;21(3):418-29 21488077 - Hepatology. 2011 Jul;54(1):262-72 11509584 - J Immunol. 2001 Sep 1;167(5):2459-68 12974479 - Nat Rev Immunol. 2003 Aug;3(8):642-55 11812991 - Nat Immunol. 2002 Feb;3(2):143-50 19931152 - Cell. 2009 Nov 25;139(5):891-906 21368224 - J Immunol. 2011 Apr 1;186(7):4147-55 15549095 - Nature. 2004 Nov 18;432(7015):332-7 22634002 - Biochem Biophys Res Commun. 2012 Jun 22;423(1):60-6 22293174 - J Clin Invest. 2012 Mar;122(3):899-910 25998961 - Nat Rev Immunol. 2015 Jun;15(6):350-61 17560334 - Cancer Cell. 2007 Jun;11(6):526-38 21436454 - Science. 2011 Mar 25;331(6024):1612-6 24498556 - Oncoimmunology. 2013 Dec 1;2(12):e26836 19669642 - Cancer Immunol Immunother. 2010 Feb;59(2):267-77 10706681 - J Immunol. 2000 Mar 15;164(6):2947-54 9845545 - Blood. 1998 Dec 15;92(12):4778-91 18216324 - Arterioscler Thromb Vasc Biol. 2008 Feb;28(2):e4; author reply e5-6 18086923 - J Cell Biol. 2007 Dec 17;179(6):1311-23 14982507 - Allergy. 2004 Mar;59(3):268-75 21917992 - Cold Spring Harb Perspect Biol. 2011 Dec 01;3(12):null 22896693 - Clin Cancer Res. 2012 Aug 15;18(16):4266-76 15766659 - Cancer Cell. 2005 Mar;7(3):211-7 24856585 - Cancer Cell. 2014 Jun 16;25(6):735-47 8640769 - Cancer Res. 1996 Mar 1;56(5):1111-17 15843517 - J Immunol. 2005 May 1;174(9):5215-23 23649148 - Cell Mol Life Sci. 2013 Dec;70(23):4431-48 17560335 - Cancer Cell. 2007 Jun;11(6):539-54 19054589 - Trends Genet. 2009 Jan;25(1):30-8 24277834 - Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):20212-7 23329041 - Science. 2013 Jan 18;339(6117):286-91 20184663 - J Cell Mol Med. 2011 Mar;15(3):635-46 16188933 - J Cell Sci. 2005 Oct 15;118(Pt 20):4731-9 12881305 - Blood. 2003 Nov 15;102(10):3837-44 20495537 - Mod Pathol. 2010 Aug;23(8):1104-12 25428504 - Nature. 2014 Nov 27;515(7528):563-7 22850419 - Cancer Res. 2012 Aug 15;72(16):3997-4007 14579280 - Eur J Immunol. 2003 Nov;33(11):3117-26 11025665 - Nat Cell Biol. 2000 Oct;2(10):737-44 19480853 - Hum Immunol. 2009 Jun;70(6):375-82 10523615 - J Exp Med. 1999 Oct 18;190(8):1175-82 20948437 - J Immunother. 2010 Nov-Dec;33(9):991-8 15286728 - Nat Rev Immunol. 2004 Aug;4(8):617-29 17100564 - Curr Cancer Drug Targets. 2006 Nov;6(7):565-78 20220849 - Nature. 2010 Mar 11;464(7286):302-5 17106243 - Cancer Biol Ther. 2006 Dec;5(12):1640-6 18039100 - Annu Rev Pathol. 2007;2:251-75 2477841 - Proc Natl Acad Sci U S A. 1989 Oct;86(19):7437-41 17768418 - Immunol Cell Biol. 2008 Jan;86(1):92-7 22763439 - Nature. 2012 Jul 26;487(7408):500-4 22308364 - Proc Natl Acad Sci U S A. 2012 Feb 14;109(7):2497-502 20176801 - J Exp Med. 2010 Mar 15;207 (3):505-20 15231578 - Blood. 2004 Oct 15;104(8):2224-34 16794736 - J Clin Invest. 2006 Jul;116(7):1955-62 12883993 - Cell Tissue Res. 2003 Oct;314(1):15-23 17404090 - Clin Cancer Res. 2007 Apr 1;13(7):2082-90 18064003 - Nature. 2007 Dec 6;450(7171):825-31 23785117 - J Immunol. 2013 Jul 15;191(2):971-81 19717280 - J Autoimmun. 2010 Feb;34(1):1-6 18825130 - Nat Rev Immunol. 2008 Oct;8(10):764-75 21326202 - Nature. 2011 Feb 24;470(7335):548-53 25177210 - BMC Clin Pathol. 2014 Aug 23;14:38 19028920 - Circ Res. 2008 Nov 21;103(11):1204-19 21846823 - Cancer Res. 2011 Sep 1;71(17):5678-87 23873014 - Med Oncol. 2013;30(3):663 17906636 - Nat Med. 2007 Oct;13(10):1211-8 15488763 - Cancer Cell. 2004 Oct;6(4):409-21 25968334 - Nat Commun. 2015 May 13;6:7114 18829565 - Cancer Res. 2008 Oct 1;68(19):8066-75 22466618 - Gut. 2013 Jan;62(1):112-20 12244148 - J Immunol. 2002 Oct 1;169(7):3581-8 25849134 - Nat Med. 2015 May;21(5):524-9 25267627 - Proc Natl Acad Sci U S A. 2014 Oct 14;111(41):14776-81 10657674 - J Immunol. 2000 Feb 15;164(4):2193-9 8695814 - Blood. 1996 Jul 15;88(2):667-73 22362216 - Nat Rev Cancer. 2012 Feb 24;12(3):210-9 21460203 - J Immunol. 2011 May 15;186(10):5549-55 16572188 - Nat Rev Cancer. 2006 May;6(5):392-401 17114237 - Cancer Res. 2006 Dec 1;66(23):11238-46 21213212 - Int J Cancer. 2011 Dec 1;129(11):2651-61 24905362 - Nat Commun. 2014 Jun 06;5:3989 21051638 - Science. 2010 Nov 5;330(6005):827-30 16891410 - Proc Natl Acad Sci U S A. 2006 Aug 15;103(33):12493-8 21277871 - Microvasc Res. 2011 May;81(3):261-8 21742796 - Physiol Rev. 2011 Jul;91(3):1071-121 20978210 - Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19461-6 22516258 - Cancer Cell. 2012 Apr 17;21(4):488-503 12615905 - J Exp Med. 2003 Mar 3;197(5):643-56 17476344 - J Clin Invest. 2007 May;117(5):1147-54 19924430 - Histochem Cell Biol. 2010 Feb;133(2):201-11 14561699 - J Clin Invest. 2003 Oct;112(8):1142-51 19279573 - Nat Rev Cancer. 2009 Apr;9(4):239-52 11980922 - J Cell Biol. 2002 Apr 29;157(3):509-19 24296878 - Lab Invest. 2014 Feb;94(2):182-91 24060865 - Nat Rev Cancer. 2013 Oct;13(10 ):739-52 10364156 - Genes Dev. 1999 Jun 1;13(11):1382-97 18025475 - Proc Natl Acad Sci U S A. 2007 Nov 27;104(48):19055-60 23890059 - Immunity. 2013 Jul 25;39(1):1-10 16920945 - J Immunol. 2006 Sep 1;177(5):3082-8 8840975 - Cancer Res. 1996 Oct 15;56(20):4625-9 24778279 - Cancer Immunol Res. 2014 Feb;2(2):154-66 12115579 - Int J Cancer. 2002 Jul 1;100(1):2-8 17237399 - J Immunol. 2007 Feb 1;178(3):1505-11 25035953 - Immunity. 2014 Jul 17;41(1):49-61 22675661 - Cold Spring Harb Perspect Med. 2012 Jun;2(6):a006494 22842476 - Nat Med. 2012 Aug;18(8):1262-70 10461061 - Oncology. 1999;57(2):138-42 24090655 - J Neuroimmunol. 2013 Dec 15;265(1-2):106-16 11839666 - Clin Cancer Res. 2002 Feb;8(2):471-80 2455691 - Int J Cancer. 1988 Jul 15;42(1):48-52 17888580 - Biochim Biophys Acta. 2007 Dec;1776(2):160-74 12172545 - Nat Immunol. 2002 Sep;3(9):844-51 24793239 - Nat Med. 2014 Jun;20(6):607-15 19276286 - Clin Cancer Res. 2009 Mar 15;15(6):2148-57 17363526 - Clin Cancer Res. 2007 Mar 15;13(6):1736-41 24084631 - Nat Commun. 2013;4:2516 C Bouzin (BFnri3902_CR18) 2007; 178 I Takanami (BFnri3902_CR98) 1999; 57 GL Beatty (BFnri3902_CR112) 2011; 331 LR Henry (BFnri3902_CR122) 2007; 13 PP Provenzano (BFnri3902_CR34) 2012; 21 MI Reinhold (BFnri3902_CR90) 1997; 185 WC Parks (BFnri3902_CR94) 2004; 4 JK Mulligan (BFnri3902_CR49) 2009; 70 CP Ng (BFnri3902_CR58) 2005; 118 M Kraman (BFnri3902_CR84) 2010; 330 T Onita (BFnri3902_CR97) 2002; 8 J Goc (BFnri3902_CR143) 2013; 2 M Ahmadzadeh (BFnri3902_CR75) 2005; 174 M Loeffler (BFnri3902_CR25) 2006; 116 JH Kim (BFnri3902_CR82) 2012; 423 PC Maciag (BFnri3902_CR126) 2008; 68 JI Greenberg (BFnri3902_CR12) 2008; 456 W Zhao (BFnri3902_CR64) 2011; 129 F Shojaei (BFnri3902_CR102) 2007; 450 S Ichikawa (BFnri3902_CR62) 2011; 186 C LeBedis (BFnri3902_CR131) 2002; 100 AW Griffioen (BFnri3902_CR17) 1996; 56 W Zhao (BFnri3902_CR65) 2014; 94 MG Achen (BFnri3902_CR117) 2005; 7 EY Lin (BFnri3902_CR99) 2006; 66 T Tsujino (BFnri3902_CR123) 2007; 13 D Hauzenberger (BFnri3902_CR86) 1999; 29 S Seaman (BFnri3902_CR45) 2007; 11 AD Rhim (BFnri3902_CR38) 2014; 25 T Junt (BFnri3902_CR139) 2008; 8 MA Swartz (BFnri3902_CR57) 2012; 12 Z Han (BFnri3902_CR72) 2011; 15 M Armant (BFnri3902_CR88) 1999; 190 T Powles (BFnri3902_CR6) 2014; 515 L Soucek (BFnri3902_CR105) 2007; 13 JR Starkey (BFnri3902_CR106) 1988; 42 JD Shields (BFnri3902_CR133) 2007; 11 P Secchiero (BFnri3902_CR47) 2008; 28 PJ Wipff (BFnri3902_CR59) 2007; 179 RJ Buckanovich (BFnri3902_CR19) 2008; 14 D Liao (BFnri3902_CR26) 2009; 4 T Li (BFnri3902_CR79) 2013; 30 E Peranzoni (BFnri3902_CR135) 2013; 70 AD Steg (BFnri3902_CR137) 2012; 18 I Caruana (BFnri3902_CR36) 2015; 21 S Delfortrie (BFnri3902_CR20) 2011; 71 NA Bhowmick (BFnri3902_CR129) 2004; 432 A Valujskikh (BFnri3902_CR39) 2002; 3 J Hamzah (BFnri3902_CR14) 2008; 453 F Balkwill (BFnri3902_CR109) 2005; 7 AW Lund (BFnri3902_CR127) 2010; 15 BC Ozdemir (BFnri3902_CR37) 2014; 25 S Shalapour (BFnri3902_CR31) 2015; 521 FA Schildberg (BFnri3902_CR63) 2011; 54 LC Wang (BFnri3902_CR85) 2014; 2 S Dulauroy (BFnri3902_CR69) 2012; 18 M Gnecchi (BFnri3902_CR73) 2008; 103 AW Griffioen (BFnri3902_CR16) 1996; 88 GT Motz (BFnri3902_CR48) 2014; 20 G Bergers (BFnri3902_CR101) 2000; 2 L Pilotte (BFnri3902_CR53) 2012; 109 M Terabe (BFnri3902_CR113) 2004; 53 ES Nakasone (BFnri3902_CR3) 2012; 21 C Menetrier-Caux (BFnri3902_CR83) 1998; 92 A Textor (BFnri3902_CR116) 2014; 74 K Polyak (BFnri3902_CR2) 2009; 25 R Noy (BFnri3902_CR111) 2014; 41 A Bose (BFnri3902_CR68) 2013; 191 W Tan (BFnri3902_CR28) 2011; 470 N Rodig (BFnri3902_CR42) 2003; 33 P Lu (BFnri3902_CR110) 2011; 3 L Yang (BFnri3902_CR103) 2004; 6 JJ Montesinos (BFnri3902_CR71) 2013; 22 D Malhotra (BFnri3902_CR140) 2013; 251 K Ochs (BFnri3902_CR67) 2013; 265 AN Vallejo (BFnri3902_CR91) 2000; 164 JL Gommerman (BFnri3902_CR115) 2003; 3 PC Tumeh (BFnri3902_CR8) 2014; 515 G Tiegs (BFnri3902_CR61) 2010; 34 EF Saunier (BFnri3902_CR74) 2006; 6 JA Joyce (BFnri3902_CR1) 2009; 9 M Balsamo (BFnri3902_CR78) 2009; 106 LM Coussens (BFnri3902_CR95) 2013; 339 A Pivarcsi (BFnri3902_CR5) 2007; 104 L Peduto (BFnri3902_CR141) 2009; 182 H Sugimoto (BFnri3902_CR121) 2006; 5 C Feig (BFnri3902_CR128) 2012; 18 KR Levental (BFnri3902_CR132) 2009; 139 BA Tamburini (BFnri3902_CR56) 2014; 5 JE Talmadge (BFnri3902_CR24) 2013; 13 X Huang (BFnri3902_CR44) 2010; 207 JK Mulligan (BFnri3902_CR50) 2010; 59 L De Monte (BFnri3902_CR80) 2011; 208 LE Olson (BFnri3902_CR66) 2011; 20 DS Chen (BFnri3902_CR4) 2013; 39 JN Cohen (BFnri3902_CR55) 2010; 207 R Straussman (BFnri3902_CR136) 2012; 487 JD Peske (BFnri3902_CR146) 2015; 6 MM Mueller (BFnri3902_CR120) 2004; 4 LM Coussens (BFnri3902_CR104) 1999; 13 D Nummer (BFnri3902_CR22) 2007; 99 O Adotevi (BFnri3902_CR118) 2010; 33 M Ammirante (BFnri3902_CR30) 2014; 111 X Zang (BFnri3902_CR41) 2010; 23 JS Ko (BFnri3902_CR119) 2009; 15 RD Leek (BFnri3902_CR96) 1996; 56 JA Nagy (BFnri3902_CR10) 2007; 2 AL Fletcher (BFnri3902_CR138) 2015; 15 SN Byrne (BFnri3902_CR77) 2008; 86 CR Ruegg (BFnri3902_CR87) 1989; 86 A Munitz (BFnri3902_CR107) 2004; 59 C Germain (BFnri3902_CR145) 2014; 189 S Goel (BFnri3902_CR15) 2011; 91 M Ammirante (BFnri3902_CR114) 2010; 464 H Strnad (BFnri3902_CR130) 2010; 133 C Pitzalis (BFnri3902_CR142) 2014; 14 F Djouad (BFnri3902_CR70) 2003; 102 L Martinet (BFnri3902_CR147) 2011; 71 L Ma (BFnri3902_CR46) 2010; 107 RS Herbst (BFnri3902_CR7) 2014; 515 S Shetty (BFnri3902_CR21) 2011; 186 K Casos (BFnri3902_CR51) 2011; 81 V Paunescu (BFnri3902_CR81) 2011; 15 AR Schenkel (BFnri3902_CR23) 2002; 3 DH Munn (BFnri3902_CR52) 2007; 117 Z Li (BFnri3902_CR93) 2002; 157 A Cipponi (BFnri3902_CR148) 2012; 72 H Salmon (BFnri3902_CR33) 2012; 122 AY Savinov (BFnri3902_CR40) 2003; 197 AM Wirsing (BFnri3902_CR144) 2014; 14 C Feig (BFnri3902_CR29) 2013; 110 L Broderick (BFnri3902_CR76) 2006; 177 A Abramsson (BFnri3902_CR124) 2003; 112 VP Chauhan (BFnri3902_CR134) 2013; 4 MM Mazanet (BFnri3902_CR43) 2002; 169 K Castermans (BFnri3902_CR9) 2007; 1776 J Ahamed (BFnri3902_CR60) 2008; 112 CE Demeure (BFnri3902_CR89) 2000; 164 H Nozawa (BFnri3902_CR100) 2006; 103 C Murdoch (BFnri3902_CR27) 2004; 104 M Furuya (BFnri3902_CR13) 2004; 203 A Zumsteg (BFnri3902_CR108) 2012; 2 H Gerhardt (BFnri3902_CR125) 2003; 314 RK Jain (BFnri3902_CR11) 2003; 9 R Kalluri (BFnri3902_CR32) 2006; 6 MA Jacobetz (BFnri3902_CR35) 2013; 62 MN Avice (BFnri3902_CR92) 2001; 167 AW Lund (BFnri3902_CR54) 2012; 1
References_xml	– volume: 453 start-page: 410 year: 2008 end-page: 414 ident: CR14 article-title: Vascular normalization in Rgs5-deficient tumours promotes immune destruction publication-title: Nature doi: 10.1038/nature06868 contributor: fullname: Hamzah – volume: 13 start-page: 739 year: 2013 end-page: 752 ident: CR24 article-title: History of myeloid-derived suppressor cells publication-title: Nat. Rev. Cancer doi: 10.1038/nrc3581 contributor: fullname: Gabrilovich – volume: 54 start-page: 262 year: 2011 end-page: 272 ident: CR63 article-title: Murine hepatic stellate cells veto CD8 T cell activation by a CD54-dependent mechanism publication-title: Hepatology doi: 10.1002/hep.24352 contributor: fullname: Schildberg – volume: 107 start-page: 19461 year: 2010 end-page: 19466 ident: CR46 article-title: Ig gene-like molecule CD31 plays a nonredundant role in the regulation of T-cell immunity and tolerance publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.1011748107 contributor: fullname: Ma – volume: 15 start-page: 2148 year: 2009 end-page: 2157 ident: CR119 article-title: Sunitinib mediates reversal of myeloid-derived suppressor cell accumulation in renal cell carcinoma patients publication-title: Clin. Cancer Res. doi: 10.1158/1078-0432.CCR-08-1332 contributor: fullname: Ko – volume: 81 start-page: 261 year: 2011 end-page: 268 ident: CR51 article-title: Tumor cells induce COX-2 and mPGES-1 expression in microvascular endothelial cells mainly by means of IL-1 receptor activation publication-title: Microvasc. Res. doi: 10.1016/j.mvr.2011.01.006 contributor: fullname: Casos – volume: 133 start-page: 201 year: 2010 end-page: 211 ident: CR130 article-title: Head and neck squamous cancer stromal fibroblasts produce growth factors influencing phenotype of normal human keratinocytes publication-title: Histochem. Cell Biol. doi: 10.1007/s00418-009-0661-6 contributor: fullname: Strnad – volume: 21 start-page: 524 year: 2015 end-page: 529 ident: CR36 article-title: Heparanase promotes tumor infiltration and antitumor activity of CAR-redirected T lymphocytes publication-title: Nat. Med. doi: 10.1038/nm.3833 contributor: fullname: Caruana – volume: 112 start-page: 1142 year: 2003 end-page: 1151 ident: CR124 article-title: Endothelial and nonendothelial sources of PDGF-B regulate pericyte recruitment and influence vascular pattern formation in tumors publication-title: J. Clin. Invest. doi: 10.1172/JCI200318549 contributor: fullname: Betsholtz – volume: 116 start-page: 1955 year: 2006 end-page: 1962 ident: CR25 article-title: Targeting tumor-associated fibroblasts improves cancer chemotherapy by increasing intratumoral drug uptake publication-title: J. Clin. Invest. doi: 10.1172/JCI26532 contributor: fullname: Reisfeld – volume: 71 start-page: 7176 year: 2011 end-page: 7186 ident: CR20 article-title: Egfl7 promotes tumor escape from immunity by repressing endothelial cell activation publication-title: Cancer Res. doi: 10.1158/0008-5472.CAN-11-1301 contributor: fullname: Delfortrie – volume: 20 start-page: 607 year: 2014 end-page: 615 ident: CR48 article-title: Tumor endothelium FasL establishes a selective immune barrier promoting tolerance in tumors publication-title: Nat. Med. doi: 10.1038/nm.3541 contributor: fullname: Motz – volume: 118 start-page: 4731 year: 2005 end-page: 4739 ident: CR58 article-title: Interstitial fluid flow induces myofibroblast differentiation and collagen alignment publication-title: J. Cell Sci. doi: 10.1242/jcs.02605 contributor: fullname: Swartz – volume: 70 start-page: 375 year: 2009 end-page: 382 ident: CR49 article-title: Secretion of vascular endothelial growth factor by oral squamous cell carcinoma cells skews endothelial cells to suppress T-cell functions publication-title: Hum. Immunol. doi: 10.1016/j.humimm.2009.01.014 contributor: fullname: Young – volume: 99 start-page: 1188 year: 2007 end-page: 1199 ident: CR22 article-title: Role of tumor endothelium in CD4 CD25 regulatory T cell infiltration of human pancreatic carcinoma publication-title: J. Natl Cancer Inst. doi: 10.1093/jnci/djm064 contributor: fullname: Nummer – volume: 59 start-page: 267 year: 2010 end-page: 277 ident: CR50 article-title: Tumors induce the formation of suppressor endothelial cells publication-title: Cancer Immunol. Immunother. doi: 10.1007/s00262-009-0747-y contributor: fullname: Young – volume: 57 start-page: 138 year: 1999 end-page: 142 ident: CR98 article-title: Tumor-associated macrophage infiltration in pulmonary adenocarcinoma: association with angiogenesis and poor prognosis publication-title: Oncology doi: 10.1159/000012021 contributor: fullname: Kodaira – volume: 4 start-page: 839 year: 2004 end-page: 849 ident: CR120 article-title: Friends or foes — bipolar effects of the tumour stroma in cancer publication-title: Nat. Rev. Cancer doi: 10.1038/nrc1477 contributor: fullname: Fusenig – volume: 6 start-page: 565 year: 2006 end-page: 578 ident: CR74 article-title: TGF β inhibition for cancer therapy publication-title: Curr. Cancer Drug Targets doi: 10.2174/156800906778742460 contributor: fullname: Akhurst – volume: 515 start-page: 563 year: 2014 end-page: 567 ident: CR7 article-title: Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients publication-title: Nature doi: 10.1038/nature14011 contributor: fullname: Herbst – volume: 174 start-page: 5215 year: 2005 end-page: 5223 ident: CR75 article-title: TGF-β 1 attenuates the acquisition and expression of effector function by tumor antigen-specific human memory CD8 T cells publication-title: J. Immunol. doi: 10.4049/jimmunol.174.9.5215 contributor: fullname: Rosenberg – volume: 14 start-page: 38 year: 2014 ident: CR144 article-title: Characterisation and prognostic value of tertiary lymphoid structures in oral squamous cell carcinoma publication-title: BMC Clin. Pathol. doi: 10.1186/1472-6890-14-38 contributor: fullname: Hadler-Olsen – volume: 104 start-page: 2224 year: 2004 end-page: 2234 ident: CR27 article-title: Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues publication-title: Blood doi: 10.1182/blood-2004-03-1109 contributor: fullname: Lewis – volume: 6 start-page: 392 year: 2006 end-page: 401 ident: CR32 article-title: Fibroblasts in cancer publication-title: Nat. Rev. Cancer doi: 10.1038/nrc1877 contributor: fullname: Zeisberg – volume: 22 start-page: 2508 year: 2013 end-page: 2519 ident: CR71 article-title: evidence of the presence of mesenchymal stromal cells in cervical cancer and their role in protecting cancer cells from cytotoxic T cell activity publication-title: Stem Cells Dev. doi: 10.1089/scd.2013.0084 contributor: fullname: Montesinos – volume: 39 start-page: 1 year: 2013 end-page: 10 ident: CR4 article-title: Oncology meets immunology: the cancer-immunity cycle publication-title: Immunity doi: 10.1016/j.immuni.2013.07.012 contributor: fullname: Mellman – volume: 74 start-page: 6796 year: 2014 end-page: 6805 ident: CR116 article-title: Efficacy of CAR T-cell therapy in large tumors relies upon stromal targeting by IFNγ publication-title: Cancer Res. doi: 10.1158/0008-5472.CAN-14-0079 contributor: fullname: Textor – volume: 207 start-page: 505 year: 2010 end-page: 520 ident: CR44 article-title: Lymphoma endothelium preferentially expresses Tim-3 and facilitates the progression of lymphoma by mediating immune evasion publication-title: J. Exp. Med. doi: 10.1084/jem.20090397 contributor: fullname: Huang – volume: 25 start-page: 30 year: 2009 end-page: 38 ident: CR2 article-title: Co-evolution of tumor cells and their microenvironment publication-title: Trends Genet. doi: 10.1016/j.tig.2008.10.012 contributor: fullname: Campbell – volume: 185 start-page: 1 year: 1997 end-page: 11 ident: CR90 article-title: Costimulation of T cell activation by integrin-associated protein (CD47) is an adhesion-dependent, CD28-independent signaling pathway publication-title: J. Exp. Med. doi: 10.1084/jem.185.1.1 contributor: fullname: Brown – volume: 4 start-page: 2516 year: 2013 ident: CR134 article-title: Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels publication-title: Nat. Commun. doi: 10.1038/ncomms3516 contributor: fullname: Chauhan – volume: 11 start-page: 539 year: 2007 end-page: 554 ident: CR45 article-title: Genes that distinguish physiological and pathological angiogenesis publication-title: Cancer Cell doi: 10.1016/j.ccr.2007.04.017 contributor: fullname: Seaman – volume: 179 start-page: 1311 year: 2007 end-page: 1323 ident: CR59 article-title: Myofibroblast contraction activates latent TGF-β1 from the extracellular matrix publication-title: J. Cell Biol. doi: 10.1083/jcb.200704042 contributor: fullname: Hinz – volume: 62 start-page: 112 year: 2013 end-page: 120 ident: CR35 article-title: Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer publication-title: Gut doi: 10.1136/gutjnl-2012-302529 contributor: fullname: Jacobetz – volume: 25 start-page: 735 year: 2014 end-page: 747 ident: CR38 article-title: Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma publication-title: Cancer Cell doi: 10.1016/j.ccr.2014.04.021 contributor: fullname: Rhim – volume: 56 start-page: 4625 year: 1996 end-page: 4629 ident: CR96 article-title: Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma publication-title: Cancer Res. contributor: fullname: Leek – volume: 6 start-page: 7114 year: 2015 ident: CR146 article-title: Effector lymphocyte-induced lymph node-like vasculature enables naive T-cell entry into tumours and enhanced anti-tumour immunity publication-title: Nat. Commun. doi: 10.1038/ncomms8114 contributor: fullname: Peske – volume: 100 start-page: 2 year: 2002 end-page: 8 ident: CR131 article-title: Peripheral lymph node stromal cells can promote growth and tumorigenicity of breast carcinoma cells through the release of IGF-I and EGF publication-title: Int. J. Cancer doi: 10.1002/ijc.10481 contributor: fullname: Brodt – volume: 18 start-page: 1262 year: 2012 end-page: 1270 ident: CR69 article-title: Lineage tracing and genetic ablation of ADAM12 perivascular cells identify a major source of profibrotic cells during acute tissue injury publication-title: Nat. Med. doi: 10.1038/nm.2848 contributor: fullname: Peduto – volume: 71 start-page: 5678 year: 2011 end-page: 5687 ident: CR147 article-title: Human solid tumors contain high endothelial venules: association with T- and B-lymphocyte infiltration and favorable prognosis in breast cancer publication-title: Cancer Res. doi: 10.1158/0008-5472.CAN-11-0431 contributor: fullname: Martinet – volume: 86 start-page: 92 year: 2008 end-page: 97 ident: CR77 article-title: TGFβ is responsible for skin tumour infiltration by macrophages enabling the tumours to escape immune destruction publication-title: Immunol. Cell Biol. doi: 10.1038/sj.icb.7100116 contributor: fullname: Halliday – volume: 15 start-page: 635 year: 2011 end-page: 646 ident: CR81 article-title: Tumour-associated fibroblasts and mesenchymal stem cells: more similarities than differences publication-title: J. Cell. Mol. Med. doi: 10.1111/j.1582-4934.2010.01044.x contributor: fullname: Paunescu – volume: 68 start-page: 8066 year: 2008 end-page: 8075 ident: CR126 article-title: Cancer immunotherapy targeting the high molecular weight melanoma-associated antigen protein results in a broad antitumor response and reduction of pericytes in the tumor vasculature publication-title: Cancer Res. doi: 10.1158/0008-5472.CAN-08-0287 contributor: fullname: Paterson – volume: 330 start-page: 827 year: 2010 end-page: 830 ident: CR84 article-title: Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein-α publication-title: Science doi: 10.1126/science.1195300 contributor: fullname: Kraman – volume: 4 start-page: 617 year: 2004 end-page: 629 ident: CR94 article-title: Matrix metalloproteinases as modulators of inflammation and innate immunity publication-title: Nat. Rev. Immunol. doi: 10.1038/nri1418 contributor: fullname: Lopez-Boado – volume: 15 start-page: 2343 year: 2011 end-page: 2352 ident: CR72 article-title: Immunosuppressive effect of bone marrow-derived mesenchymal stem cells in inflammatory microenvironment favours the growth of B16 melanoma cells publication-title: J. Cell. Mol. Med. doi: 10.1111/j.1582-4934.2010.01215.x contributor: fullname: Han – volume: 2 start-page: a006494 year: 2012 ident: CR108 article-title: Myeloid cells and lymphangiogenesis publication-title: Cold Spring Harb. Perspect. Med. doi: 10.1101/cshperspect.a006494 contributor: fullname: Christofori – volume: 487 start-page: 500 year: 2012 end-page: 504 ident: CR136 article-title: Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion publication-title: Nature doi: 10.1038/nature11183 contributor: fullname: Straussman – volume: 129 start-page: 2651 year: 2011 end-page: 2661 ident: CR64 article-title: Activated hepatic stellate cells promote hepatocellular carcinoma development in immunocompetent mice publication-title: Int. J. Cancer doi: 10.1002/ijc.25920 contributor: fullname: Zhao – volume: 112 start-page: 3650 year: 2008 end-page: 3660 ident: CR60 article-title: and evidence for shear-induced activation of latent transforming growth factor-β1 publication-title: Blood doi: 10.1182/blood-2008-04-151753 contributor: fullname: Ahamed – volume: 186 start-page: 4147 year: 2011 end-page: 4155 ident: CR21 article-title: Common lymphatic endothelial and vascular endothelial receptor-1 mediates the transmigration of regulatory T cells across human hepatic sinusoidal endothelium publication-title: J. Immunol. doi: 10.4049/jimmunol.1002961 contributor: fullname: Shetty – volume: 2 start-page: 251 year: 2007 end-page: 275 ident: CR10 article-title: VEGF-A and the induction of pathological angiogenesis publication-title: Annu. Rev. Pathol. doi: 10.1146/annurev.pathol.2.010506.134925 contributor: fullname: Dvorak – volume: 20 start-page: 815 year: 2011 end-page: 826 ident: CR66 article-title: PDGFRβ signaling regulates mural cell plasticity and inhibits fat development publication-title: Dev. Cell doi: 10.1016/j.devcel.2011.04.019 contributor: fullname: Soriano – volume: 182 start-page: 5789 year: 2009 end-page: 5799 ident: CR141 article-title: Inflammation recapitulates the ontogeny of lymphoid stromal cells publication-title: J. Immunol. doi: 10.4049/jimmunol.0803974 contributor: fullname: Peduto – volume: 109 start-page: 2497 year: 2012 end-page: 2502 ident: CR53 article-title: Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.1113873109 contributor: fullname: Pilotte – volume: 190 start-page: 1175 year: 1999 end-page: 1182 ident: CR88 article-title: CD47 ligation selectively downregulates human interleukin 12 production publication-title: J. Exp. Med. doi: 10.1084/jem.190.8.1175 contributor: fullname: Armant – volume: 103 start-page: 12493 year: 2006 end-page: 12498 ident: CR100 article-title: Infiltrating neutrophils mediate the initial angiogenic switch in a mouse model of multistage carcinogenesis publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.0601807103 contributor: fullname: Hanahan – volume: 7 start-page: 211 year: 2005 end-page: 217 ident: CR109 article-title: Smoldering and polarized inflammation in the initiation and promotion of malignant disease publication-title: Cancer Cell doi: 10.1016/j.ccr.2005.02.013 contributor: fullname: Mantovani – volume: 139 start-page: 891 year: 2009 end-page: 906 ident: CR132 article-title: Matrix crosslinking forces tumor progression by enhancing integrin signaling publication-title: Cell doi: 10.1016/j.cell.2009.10.027 contributor: fullname: Levental – volume: 117 start-page: 1147 year: 2007 end-page: 1154 ident: CR52 article-title: Indoleamine 2,3-dioxygenase and tumor-induced tolerance publication-title: J. Clin. Invest. doi: 10.1172/JCI31178 contributor: fullname: Mellor – volume: 5 start-page: 1640 year: 2006 end-page: 1646 ident: CR121 article-title: Identification of fibroblast heterogeneity in the tumor microenvironment publication-title: Cancer Biol. Ther. doi: 10.4161/cbt.5.12.3354 contributor: fullname: Kalluri – volume: 1 start-page: 191 year: 2012 end-page: 199 ident: CR54 article-title: VEGF-C promotes immune tolerance in B16 melanomas and cross-presentation of tumor antigen by lymph node lymphatics publication-title: Cell Rep. doi: 10.1016/j.celrep.2012.01.005 contributor: fullname: Lund – volume: 169 start-page: 3581 year: 2002 end-page: 3588 ident: CR43 article-title: B7-H1 is expressed by human endothelial cells and suppresses T cell cytokine synthesis publication-title: J. Immunol. doi: 10.4049/jimmunol.169.7.3581 contributor: fullname: Hughes – volume: 111 start-page: 14776 year: 2014 end-page: 14781 ident: CR30 article-title: Tissue injury and hypoxia promote malignant progression of prostate cancer by inducing CXCL13 expression in tumor myofibroblasts publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.1416498111 contributor: fullname: Karin – volume: 5 start-page: 3989 year: 2014 ident: CR56 article-title: Antigen capture and archiving by lymphatic endothelial cells following vaccination or viral infection publication-title: Nat. Commun. doi: 10.1038/ncomms4989 contributor: fullname: Kedl – volume: 3 start-page: 844 year: 2002 end-page: 851 ident: CR39 article-title: Cross-primed CD8 T cells mediate graft rejection via a distinct effector pathway publication-title: Nat. Immunol. doi: 10.1038/ni831 contributor: fullname: Heeger – volume: 191 start-page: 971 year: 2013 end-page: 981 ident: CR68 article-title: Tumor-derived vascular pericytes anergize Th cells publication-title: J. Immunol. doi: 10.4049/jimmunol.1300280 contributor: fullname: Bose – volume: 167 start-page: 2459 year: 2001 end-page: 2468 ident: CR92 article-title: Role of CD47 in the induction of human naive T cell anergy publication-title: J. Immunol. doi: 10.4049/jimmunol.167.5.2459 contributor: fullname: Sarfati – volume: 9 start-page: 685 year: 2003 end-page: 693 ident: CR11 article-title: Molecular regulation of vessel maturation publication-title: Nat. Med. doi: 10.1038/nm0603-685 contributor: fullname: Jain – volume: 177 start-page: 3082 year: 2006 end-page: 3088 ident: CR76 article-title: Membrane-associated TGF-β1 inhibits human memory T cell signaling in malignant and nonmalignant inflammatory microenvironments publication-title: J. Immunol. doi: 10.4049/jimmunol.177.5.3082 contributor: fullname: Bankert – volume: 8 start-page: 764 year: 2008 end-page: 775 ident: CR139 article-title: Form follows function: lymphoid tissue microarchitecture in antimicrobial immune defence publication-title: Nat. Rev. Immunol. doi: 10.1038/nri2414 contributor: fullname: Ludewig – volume: 339 start-page: 286 year: 2013 end-page: 291 ident: CR95 article-title: Neutralizing tumor-promoting chronic inflammation: a magic bullet? publication-title: Science doi: 10.1126/science.1232227 contributor: fullname: Palucka – volume: 164 start-page: 2947 year: 2000 end-page: 2954 ident: CR91 article-title: Central role of thrombospondin-1 in the activation and clonal expansion of inflammatory T cells publication-title: J. Immunol. doi: 10.4049/jimmunol.164.6.2947 contributor: fullname: Goronzy – volume: 103 start-page: 1204 year: 2008 end-page: 1219 ident: CR73 article-title: Paracrine mechanisms in adult stem cell signaling and therapy publication-title: Circ. Res. doi: 10.1161/CIRCRESAHA.108.176826 contributor: fullname: Dzau – volume: 86 start-page: 7437 year: 1989 end-page: 7441 ident: CR87 article-title: Tenascin, an extracellular matrix protein, exerts immunomodulatory activities publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.86.19.7437 contributor: fullname: Alkan – volume: 207 start-page: 681 year: 2010 end-page: 688 ident: CR55 article-title: Lymph node-resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation publication-title: J. Exp. Med. doi: 10.1084/jem.20092465 contributor: fullname: Cohen – volume: 56 start-page: 1111 year: 1996 end-page: 1117 ident: CR17 article-title: Endothelial intercellular adhesion molecule-1 expression is suppressed in human malignancies: the role of angiogenic factors publication-title: Cancer Res. contributor: fullname: Groenewegen – volume: 203 start-page: 551 year: 2004 end-page: 558 ident: CR13 article-title: Expression of regulator of G protein signalling protein 5 (RGS5) in the tumour vasculature of human renal cell carcinoma publication-title: J. Pathol. doi: 10.1002/path.1543 contributor: fullname: Furuya – volume: 178 start-page: 1505 year: 2007 end-page: 1511 ident: CR18 article-title: Effects of vascular endothelial growth factor on the lymphocyte–endothelium interactions: identification of caveolin-1 and nitric oxide as control points of endothelial cell anergy publication-title: J. Immunol. doi: 10.4049/jimmunol.178.3.1505 contributor: fullname: Feron – volume: 6 start-page: 409 year: 2004 end-page: 421 ident: CR103 article-title: Expansion of myeloid immune suppressor Gr CD11b cells in tumor-bearing host directly promotes tumor angiogenesis publication-title: Cancer Cell doi: 10.1016/j.ccr.2004.08.031 contributor: fullname: Yang – volume: 106 start-page: 20847 year: 2009 end-page: 20852 ident: CR78 article-title: Melanoma-associated fibroblasts modulate NK cell phenotype and antitumor cytotoxicity publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.0906481106 contributor: fullname: Balsamo – volume: 28 start-page: e4 year: 2008 end-page: e6 ident: CR47 article-title: The puzzling role of TRAIL in endothelial cell biology publication-title: Arterioscler. Thromb. Vasc. Biol. doi: 10.1161/ATVBAHA.107.158451 contributor: fullname: Zauli – volume: 189 start-page: 832 year: 2014 end-page: 844 ident: CR145 article-title: Presence of B cells in tertiary lymphoid structures is associated with a protective immunity in patients with lung cancer publication-title: Am. J. Respir. Crit. Care Med. doi: 10.1164/rccm.201309-1611OC contributor: fullname: Germain – volume: 13 start-page: 1736 year: 2007 end-page: 1741 ident: CR122 article-title: Clinical implications of fibroblast activation protein in patients with colon cancer publication-title: Clin. Cancer Res. doi: 10.1158/1078-0432.CCR-06-1746 contributor: fullname: Henry – volume: 25 start-page: 719 year: 2014 end-page: 734 ident: CR37 article-title: Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival publication-title: Cancer Cell doi: 10.1016/j.ccr.2014.04.005 contributor: fullname: Ozdemir – volume: 2 start-page: 154 year: 2014 end-page: 166 ident: CR85 article-title: Targeting fibroblast activation protein in tumor stroma with chimeric antigen receptor T cells can inhibit tumor growth and augment host immunity without severe toxicity publication-title: Cancer Immunol. Res. doi: 10.1158/2326-6066.CIR-13-0027 contributor: fullname: Wang – volume: 34 start-page: 1 year: 2010 end-page: 6 ident: CR61 article-title: Immune tolerance: what is unique about the liver publication-title: J. Autoimmun. doi: 10.1016/j.jaut.2009.08.008 contributor: fullname: Lohse – volume: 41 start-page: 49 year: 2014 end-page: 61 ident: CR111 article-title: Tumor-associated macrophages: from mechanisms to therapy publication-title: Immunity doi: 10.1016/j.immuni.2014.06.010 contributor: fullname: Pollard – volume: 122 start-page: 899 year: 2012 end-page: 910 ident: CR33 article-title: Matrix architecture defines the preferential localization and migration of T cells into the stroma of human lung tumors publication-title: J. Clin. Invest. doi: 10.1172/JCI45817 contributor: fullname: Salmon – volume: 251 start-page: 160 year: 2013 end-page: 176 ident: CR140 article-title: Stromal and hematopoietic cells in secondary lymphoid organs: partners in immunity publication-title: Immunol. Rev. doi: 10.1111/imr.12023 contributor: fullname: Turley – volume: 23 start-page: 1104 year: 2010 end-page: 1112 ident: CR41 article-title: Tumor associated endothelial expression of B7-H3 predicts survival in ovarian carcinomas publication-title: Mod. Pathol. doi: 10.1038/modpathol.2010.95 contributor: fullname: Zang – volume: 11 start-page: 526 year: 2007 end-page: 538 ident: CR133 article-title: Autologous chemotaxis as a mechanism of tumor cell homing to lymphatics via interstitial flow and autocrine CCR7 signaling publication-title: Cancer Cell doi: 10.1016/j.ccr.2007.04.020 contributor: fullname: Shields – volume: 72 start-page: 3997 year: 2012 end-page: 4007 ident: CR148 article-title: Neogenesis of lymphoid structures and antibody responses occur in human melanoma metastases publication-title: Cancer Res. doi: 10.1158/0008-5472.CAN-12-1377 contributor: fullname: Cipponi – volume: 33 start-page: 3117 year: 2003 end-page: 3126 ident: CR42 article-title: Endothelial expression of PD-L1 and PD-L2 down-regulates CD8 T cell activation and cytolysis publication-title: Eur. J. Immunol. doi: 10.1002/eji.200324270 contributor: fullname: Rodig – volume: 1776 start-page: 160 year: 2007 end-page: 174 ident: CR9 article-title: Tumor blood vessels, a difficult hurdle for infiltrating leukocytes publication-title: Biochim. Biophys. Acta contributor: fullname: Griffioen – volume: 331 start-page: 1612 year: 2011 end-page: 1616 ident: CR112 article-title: CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans publication-title: Science doi: 10.1126/science.1198443 contributor: fullname: Beatty – volume: 18 start-page: 4266 year: 2012 end-page: 4276 ident: CR128 article-title: The pancreas cancer microenvironment publication-title: Clin. Cancer Res. doi: 10.1158/1078-0432.CCR-11-3114 contributor: fullname: Feig – volume: 15 start-page: 350 year: 2015 end-page: 361 ident: CR138 article-title: Lymph node fibroblastic reticular cells in health and disease publication-title: Nat. Rev. Immunol. doi: 10.1038/nri3846 contributor: fullname: Knoblich – volume: 521 start-page: 94 year: 2015 end-page: 98 ident: CR31 article-title: Immunosuppressive plasma cells impede T-cell-dependent immunogenic chemotherapy publication-title: Nature doi: 10.1038/nature14395 contributor: fullname: Shalapour – volume: 197 start-page: 643 year: 2003 end-page: 656 ident: CR40 article-title: Presentation of antigen by endothelial cells and chemoattraction are required for homing of insulin-specific CD8 T cells publication-title: J. Exp. Med. doi: 10.1084/jem.20021378 contributor: fullname: Chervonsky – volume: 94 start-page: 182 year: 2014 end-page: 191 ident: CR65 article-title: Hepatic stellate cells promote tumor progression by enhancement of immunosuppressive cells in an orthotopic liver tumor mouse model publication-title: Lab. Invest. doi: 10.1038/labinvest.2013.139 contributor: fullname: Zhao – volume: 456 start-page: 809 year: 2008 end-page: 813 ident: CR12 article-title: A role for VEGF as a negative regulator of pericyte function and vessel maturation publication-title: Nature doi: 10.1038/nature07424 contributor: fullname: Greenberg – volume: 314 start-page: 15 year: 2003 end-page: 23 ident: CR125 article-title: Endothelial–pericyte interactions in angiogenesis publication-title: Cell Tissue Res. doi: 10.1007/s00441-003-0745-x contributor: fullname: Betsholtz – volume: 8 start-page: 471 year: 2002 end-page: 480 ident: CR97 article-title: Hypoxia-induced, perinecrotic expression of endothelial Per–ARNT–Sim domain protein-1/hypoxia-inducible factor-2α correlates with tumor progression, vascularization, and focal macrophage infiltration in bladder cancer publication-title: Clin. Cancer Res. contributor: fullname: Onita – volume: 102 start-page: 3837 year: 2003 end-page: 3844 ident: CR70 article-title: Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals publication-title: Blood doi: 10.1182/blood-2003-04-1193 contributor: fullname: Djouad – volume: 30 start-page: 663 year: 2013 ident: CR79 article-title: Colorectal carcinoma-derived fibroblasts modulate natural killer cell phenotype and antitumor cytotoxicity publication-title: Med. Oncol. doi: 10.1007/s12032-013-0663-z contributor: fullname: Li – volume: 59 start-page: 268 year: 2004 end-page: 275 ident: CR107 article-title: Eosinophils: 'new' roles for 'old' cells publication-title: Allergy doi: 10.1111/j.1398-9995.2003.00442.x contributor: fullname: Levi-Schaffer – volume: 2 start-page: 737 year: 2000 end-page: 744 ident: CR101 article-title: Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis publication-title: Nat. Cell Biol. doi: 10.1038/35036374 contributor: fullname: Bergers – volume: 91 start-page: 1071 year: 2011 end-page: 1121 ident: CR15 article-title: Normalization of the vasculature for treatment of cancer and other diseases publication-title: Physiol. Rev. doi: 10.1152/physrev.00038.2010 contributor: fullname: Goel – volume: 9 start-page: 239 year: 2009 end-page: 252 ident: CR1 article-title: Microenvironmental regulation of metastasis publication-title: Nat. Rev. Cancer doi: 10.1038/nrc2618 contributor: fullname: Pollard – volume: 423 start-page: 60 year: 2012 end-page: 66 ident: CR82 article-title: The role of myofibroblasts in upregulation of S100A8 and S100A9 and the differentiation of myeloid cells in the colorectal cancer microenvironment publication-title: Biochem. Biophys. Res. Commun. doi: 10.1016/j.bbrc.2012.05.081 contributor: fullname: Kim – volume: 21 start-page: 418 year: 2012 end-page: 429 ident: CR34 article-title: Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma publication-title: Cancer Cell doi: 10.1016/j.ccr.2012.01.007 contributor: fullname: Provenzano – volume: 42 start-page: 48 year: 1988 end-page: 52 ident: CR106 article-title: Mast-cell-deficient W/Wv mice exhibit a decreased rate of tumor angiogenesis publication-title: Int. J. Cancer doi: 10.1002/ijc.2910420110 contributor: fullname: Taubenberger – volume: 15 start-page: 341 year: 2010 end-page: 352 ident: CR127 article-title: Role of lymphatic vessels in tumor immunity: passive conduits or active participants? publication-title: J. Mammary Gland Biol. Neoplasia doi: 10.1007/s10911-010-9193-x contributor: fullname: Swartz – volume: 3 start-page: 642 year: 2003 end-page: 655 ident: CR115 article-title: Lymphotoxin/LIGHT, lymphoid microenvironments and autoimmune disease publication-title: Nat. Rev. Immunol. doi: 10.1038/nri1151 contributor: fullname: Browning – volume: 7 start-page: 121 year: 2005 end-page: 127 ident: CR117 article-title: Focus on lymphangiogenesis in tumor metastasis publication-title: Cancer Cell doi: 10.1016/j.ccr.2005.01.017 contributor: fullname: Stacker – volume: 450 start-page: 825 year: 2007 end-page: 831 ident: CR102 article-title: Bv8 regulates myeloid-cell-dependent tumour angiogenesis publication-title: Nature doi: 10.1038/nature06348 contributor: fullname: Shojaei – volume: 13 start-page: 2082 year: 2007 end-page: 2090 ident: CR123 article-title: Stromal myofibroblasts predict disease recurrence for colorectal cancer publication-title: Clin. Cancer Res. doi: 10.1158/1078-0432.CCR-06-2191 contributor: fullname: Tsujino – volume: 18 start-page: 869 year: 2012 end-page: 881 ident: CR137 article-title: Stem cell pathways contribute to clinical chemoresistance in ovarian cancer publication-title: Clin. Cancer Res. doi: 10.1158/1078-0432.CCR-11-2188 contributor: fullname: Steg – volume: 33 start-page: 991 year: 2010 end-page: 998 ident: CR118 article-title: A decrease of regulatory T cells correlates with overall survival after sunitinib-based antiangiogenic therapy in metastatic renal cancer patients publication-title: J. Immunother. doi: 10.1097/CJI.0b013e3181f4c208 contributor: fullname: Adotevi – volume: 3 start-page: 143 year: 2002 end-page: 150 ident: CR23 article-title: CD99 plays a major role in the migration of monocytes through endothelial junctions publication-title: Nat. Immunol. doi: 10.1038/ni749 contributor: fullname: Muller – volume: 104 start-page: 19055 year: 2007 end-page: 19060 ident: CR5 article-title: Tumor immune escape by the loss of homeostatic chemokine expression publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.0705673104 contributor: fullname: Pivarcsi – volume: 164 start-page: 2193 year: 2000 end-page: 2199 ident: CR89 article-title: CD47 engagement inhibits cytokine production and maturation of human dendritic cells publication-title: J. Immunol. doi: 10.4049/jimmunol.164.4.2193 contributor: fullname: Demeure – volume: 14 start-page: 28 year: 2008 end-page: 36 ident: CR19 article-title: Endothelin B receptor mediates the endothelial barrier to T cell homing to tumors and disables immune therapy publication-title: Nat. Med. doi: 10.1038/nm1699 contributor: fullname: Buckanovich – volume: 66 start-page: 11238 year: 2006 end-page: 11246 ident: CR99 article-title: Macrophages regulate the angiogenic switch in a mouse model of breast cancer publication-title: Cancer Res. doi: 10.1158/0008-5472.CAN-06-1278 contributor: fullname: Lin – volume: 432 start-page: 332 year: 2004 end-page: 337 ident: CR129 article-title: Stromal fibroblasts in cancer initiation and progression publication-title: Nature doi: 10.1038/nature03096 contributor: fullname: Moses – volume: 3 start-page: a005058 year: 2011 ident: CR110 article-title: Extracellular matrix degradation and remodeling in development and disease publication-title: Cold Spring Harb. Perspect. Biol. doi: 10.1101/cshperspect.a005058 contributor: fullname: Werb – volume: 265 start-page: 106 year: 2013 end-page: 116 ident: CR67 article-title: Immature mesenchymal stem cell-like pericytes as mediators of immunosuppression in human malignant glioma publication-title: J. Neuroimmunol. doi: 10.1016/j.jneuroim.2013.09.011 contributor: fullname: Ochs – volume: 70 start-page: 4431 year: 2013 end-page: 4448 ident: CR135 article-title: Positive and negative influence of the matrix architecture on antitumor immune surveillance publication-title: Cell. Mol. Life Sci. doi: 10.1007/s00018-013-1339-8 contributor: fullname: Donnadieu – volume: 110 start-page: 20212 year: 2013 end-page: 20217 ident: CR29 article-title: Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.1320318110 contributor: fullname: Feig – volume: 464 start-page: 302 year: 2010 end-page: 305 ident: CR114 article-title: B-cell-derived lymphotoxin promotes castration-resistant prostate cancer publication-title: Nature doi: 10.1038/nature08782 contributor: fullname: Karin – volume: 88 start-page: 667 year: 1996 end-page: 673 ident: CR16 article-title: Tumor angiogenesis is accompanied by a decreased inflammatory response of tumor-associated endothelium publication-title: Blood doi: 10.1182/blood.V88.2.667.bloodjournal882667 contributor: fullname: Groenewegen – volume: 4 start-page: e7965 year: 2009 ident: CR26 article-title: Cancer associated fibroblasts promote tumor growth and metastasis by modulating the tumor immune microenvironment in a 4T1 murine breast cancer model publication-title: PLoS ONE doi: 10.1371/journal.pone.0007965 contributor: fullname: Reisfeld – volume: 470 start-page: 548 year: 2011 end-page: 553 ident: CR28 article-title: Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL–RANK signalling publication-title: Nature doi: 10.1038/nature09707 contributor: fullname: Tan – volume: 2 start-page: e26836 year: 2013 ident: CR143 article-title: Characteristics of tertiary lymphoid structures in primary cancers publication-title: Oncoimmunology doi: 10.4161/onci.26836 contributor: fullname: Dieu-Nosjean – volume: 29 start-page: 1435 year: 1999 end-page: 1447 ident: CR86 article-title: Tenascin-C inhibits β integrin-dependent T lymphocyte adhesion to fibronectin through the binding of its fnIII 1–5 repeats to fibronectin publication-title: Eur. J. Immunol. doi: 10.1002/(SICI)1521-4141(199905)29:05<1435::AID-IMMU1435>3.0.CO;2-N contributor: fullname: Ruegg – volume: 21 start-page: 488 year: 2012 end-page: 503 ident: CR3 article-title: Imaging tumor-stroma interactions during chemotherapy reveals contributions of the microenvironment to resistance publication-title: Cancer Cell doi: 10.1016/j.ccr.2012.02.017 contributor: fullname: Nakasone – volume: 13 start-page: 1211 year: 2007 end-page: 1218 ident: CR105 article-title: Mast cells are required for angiogenesis and macroscopic expansion of Myc-induced pancreatic islet tumors publication-title: Nat. Med. doi: 10.1038/nm1649 contributor: fullname: Soucek – volume: 515 start-page: 568 year: 2014 end-page: 571 ident: CR8 article-title: PD-1 blockade induces responses by inhibiting adaptive immune resistance publication-title: Nature doi: 10.1038/nature13954 contributor: fullname: Tumeh – volume: 53 start-page: 79 year: 2004 end-page: 85 ident: CR113 article-title: Role of IL-13 in regulation of anti-tumor immunity and tumor growth publication-title: Cancer Immunol. Immunother. doi: 10.1007/s00262-003-0445-0 contributor: fullname: Berzofsky – volume: 515 start-page: 558 year: 2014 end-page: 562 ident: CR6 article-title: MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer publication-title: Nature doi: 10.1038/nature13904 contributor: fullname: Powles – volume: 14 start-page: 447 year: 2014 end-page: 462 ident: CR142 article-title: Ectopic lymphoid-like structures in infection, cancer and autoimmunity publication-title: Nat. Rev. Immunol. doi: 10.1038/nri3700 contributor: fullname: Jones – volume: 12 start-page: 210 year: 2012 end-page: 219 ident: CR57 article-title: Lymphatic and interstitial flow in the tumour microenvironment: linking mechanobiology with immunity publication-title: Nat. Rev. Cancer doi: 10.1038/nrc3186 contributor: fullname: Lund – volume: 208 start-page: 469 year: 2011 end-page: 478 ident: CR80 article-title: Intratumor T helper type 2 cell infiltrate correlates with cancer-associated fibroblast thymic stromal lymphopoietin production and reduced survival in pancreatic cancer publication-title: J. Exp. Med. doi: 10.1084/jem.20101876 contributor: fullname: De Monte – volume: 157 start-page: 509 year: 2002 end-page: 519 ident: CR93 article-title: Interactions of thrombospondins with α4β1 integrin and CD47 differentially modulate T cell behavior publication-title: J. Cell Biol. doi: 10.1083/jcb.200109098 contributor: fullname: Li – volume: 92 start-page: 4778 year: 1998 end-page: 4791 ident: CR83 article-title: Inhibition of the differentiation of dendritic cells from CD34 progenitors by tumor cells: role of interleukin-6 and macrophage colony-stimulating factor publication-title: Blood doi: 10.1182/blood.V92.12.4778.424k14_4778_4791 contributor: fullname: Menetrier-Caux – volume: 186 start-page: 5549 year: 2011 end-page: 5555 ident: CR62 article-title: Hepatic stellate cells function as regulatory bystanders publication-title: J. Immunol. doi: 10.4049/jimmunol.1003917 contributor: fullname: Cheroutre – volume: 13 start-page: 1382 year: 1999 end-page: 1397 ident: CR104 article-title: Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis publication-title: Genes Dev. doi: 10.1101/gad.13.11.1382 contributor: fullname: Coussens – volume: 62 start-page: 112 year: 2013 ident: BFnri3902_CR35 publication-title: Gut doi: 10.1136/gutjnl-2012-302529 contributor: fullname: MA Jacobetz – volume: 118 start-page: 4731 year: 2005 ident: BFnri3902_CR58 publication-title: J. Cell Sci. doi: 10.1242/jcs.02605 contributor: fullname: CP Ng – volume: 18 start-page: 4266 year: 2012 ident: BFnri3902_CR128 publication-title: Clin. Cancer Res. doi: 10.1158/1078-0432.CCR-11-3114 contributor: fullname: C Feig – volume: 110 start-page: 20212 year: 2013 ident: BFnri3902_CR29 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.1320318110 contributor: fullname: C Feig – volume: 21 start-page: 418 year: 2012 ident: BFnri3902_CR34 publication-title: Cancer Cell doi: 10.1016/j.ccr.2012.01.007 contributor: fullname: PP Provenzano – volume: 104 start-page: 19055 year: 2007 ident: BFnri3902_CR5 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.0705673104 contributor: fullname: A Pivarcsi – volume: 25 start-page: 735 year: 2014 ident: BFnri3902_CR38 publication-title: Cancer Cell doi: 10.1016/j.ccr.2014.04.021 contributor: fullname: AD Rhim – volume: 11 start-page: 539 year: 2007 ident: BFnri3902_CR45 publication-title: Cancer Cell doi: 10.1016/j.ccr.2007.04.017 contributor: fullname: S Seaman – volume: 2 start-page: e26836 year: 2013 ident: BFnri3902_CR143 publication-title: Oncoimmunology doi: 10.4161/onci.26836 contributor: fullname: J Goc – volume: 102 start-page: 3837 year: 2003 ident: BFnri3902_CR70 publication-title: Blood doi: 10.1182/blood-2003-04-1193 contributor: fullname: F Djouad – volume: 1 start-page: 191 year: 2012 ident: BFnri3902_CR54 publication-title: Cell Rep. doi: 10.1016/j.celrep.2012.01.005 contributor: fullname: AW Lund – volume: 29 start-page: 1435 year: 1999 ident: BFnri3902_CR86 publication-title: Eur. J. Immunol. doi: 10.1002/(SICI)1521-4141(199905)29:05<1435::AID-IMMU1435>3.0.CO;2-N contributor: fullname: D Hauzenberger – volume: 432 start-page: 332 year: 2004 ident: BFnri3902_CR129 publication-title: Nature doi: 10.1038/nature03096 contributor: fullname: NA Bhowmick – volume: 15 start-page: 635 year: 2011 ident: BFnri3902_CR81 publication-title: J. Cell. Mol. Med. doi: 10.1111/j.1582-4934.2010.01044.x contributor: fullname: V Paunescu – volume: 207 start-page: 505 year: 2010 ident: BFnri3902_CR44 publication-title: J. Exp. Med. doi: 10.1084/jem.20090397 contributor: fullname: X Huang – volume: 71 start-page: 7176 year: 2011 ident: BFnri3902_CR20 publication-title: Cancer Res. doi: 10.1158/0008-5472.CAN-11-1301 contributor: fullname: S Delfortrie – volume: 331 start-page: 1612 year: 2011 ident: BFnri3902_CR112 publication-title: Science doi: 10.1126/science.1198443 contributor: fullname: GL Beatty – volume: 185 start-page: 1 year: 1997 ident: BFnri3902_CR90 publication-title: J. Exp. Med. doi: 10.1084/jem.185.1.1 contributor: fullname: MI Reinhold – volume: 53 start-page: 79 year: 2004 ident: BFnri3902_CR113 publication-title: Cancer Immunol. Immunother. doi: 10.1007/s00262-003-0445-0 contributor: fullname: M Terabe – volume: 182 start-page: 5789 year: 2009 ident: BFnri3902_CR141 publication-title: J. Immunol. doi: 10.4049/jimmunol.0803974 contributor: fullname: L Peduto – volume: 21 start-page: 488 year: 2012 ident: BFnri3902_CR3 publication-title: Cancer Cell doi: 10.1016/j.ccr.2012.02.017 contributor: fullname: ES Nakasone – volume: 167 start-page: 2459 year: 2001 ident: BFnri3902_CR92 publication-title: J. Immunol. doi: 10.4049/jimmunol.167.5.2459 contributor: fullname: MN Avice – volume: 13 start-page: 1736 year: 2007 ident: BFnri3902_CR122 publication-title: Clin. Cancer Res. doi: 10.1158/1078-0432.CCR-06-1746 contributor: fullname: LR Henry – volume: 3 start-page: 844 year: 2002 ident: BFnri3902_CR39 publication-title: Nat. Immunol. doi: 10.1038/ni831 contributor: fullname: A Valujskikh – volume: 3 start-page: 143 year: 2002 ident: BFnri3902_CR23 publication-title: Nat. Immunol. doi: 10.1038/ni749 contributor: fullname: AR Schenkel – volume: 92 start-page: 4778 year: 1998 ident: BFnri3902_CR83 publication-title: Blood doi: 10.1182/blood.V92.12.4778.424k14_4778_4791 contributor: fullname: C Menetrier-Caux – volume: 164 start-page: 2193 year: 2000 ident: BFnri3902_CR89 publication-title: J. Immunol. doi: 10.4049/jimmunol.164.4.2193 contributor: fullname: CE Demeure – volume: 117 start-page: 1147 year: 2007 ident: BFnri3902_CR52 publication-title: J. Clin. Invest. doi: 10.1172/JCI31178 contributor: fullname: DH Munn – volume: 9 start-page: 239 year: 2009 ident: BFnri3902_CR1 publication-title: Nat. Rev. Cancer doi: 10.1038/nrc2618 contributor: fullname: JA Joyce – volume: 6 start-page: 565 year: 2006 ident: BFnri3902_CR74 publication-title: Curr. Cancer Drug Targets doi: 10.2174/156800906778742460 contributor: fullname: EF Saunier – volume: 22 start-page: 2508 year: 2013 ident: BFnri3902_CR71 publication-title: Stem Cells Dev. doi: 10.1089/scd.2013.0084 contributor: fullname: JJ Montesinos – volume: 251 start-page: 160 year: 2013 ident: BFnri3902_CR140 publication-title: Immunol. Rev. doi: 10.1111/imr.12023 contributor: fullname: D Malhotra – volume: 6 start-page: 7114 year: 2015 ident: BFnri3902_CR146 publication-title: Nat. Commun. doi: 10.1038/ncomms8114 contributor: fullname: JD Peske – volume: 20 start-page: 607 year: 2014 ident: BFnri3902_CR48 publication-title: Nat. Med. doi: 10.1038/nm.3541 contributor: fullname: GT Motz – volume: 191 start-page: 971 year: 2013 ident: BFnri3902_CR68 publication-title: J. Immunol. doi: 10.4049/jimmunol.1300280 contributor: fullname: A Bose – volume: 423 start-page: 60 year: 2012 ident: BFnri3902_CR82 publication-title: Biochem. Biophys. Res. Commun. doi: 10.1016/j.bbrc.2012.05.081 contributor: fullname: JH Kim – volume: 208 start-page: 469 year: 2011 ident: BFnri3902_CR80 publication-title: J. Exp. Med. doi: 10.1084/jem.20101876 contributor: fullname: L De Monte – volume: 186 start-page: 4147 year: 2011 ident: BFnri3902_CR21 publication-title: J. Immunol. doi: 10.4049/jimmunol.1002961 contributor: fullname: S Shetty – volume: 86 start-page: 7437 year: 1989 ident: BFnri3902_CR87 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.86.19.7437 contributor: fullname: CR Ruegg – volume: 464 start-page: 302 year: 2010 ident: BFnri3902_CR114 publication-title: Nature doi: 10.1038/nature08782 contributor: fullname: M Ammirante – volume: 15 start-page: 350 year: 2015 ident: BFnri3902_CR138 publication-title: Nat. Rev. Immunol. doi: 10.1038/nri3846 contributor: fullname: AL Fletcher – volume: 30 start-page: 663 year: 2013 ident: BFnri3902_CR79 publication-title: Med. Oncol. doi: 10.1007/s12032-013-0663-z contributor: fullname: T Li – volume: 133 start-page: 201 year: 2010 ident: BFnri3902_CR130 publication-title: Histochem. Cell Biol. doi: 10.1007/s00418-009-0661-6 contributor: fullname: H Strnad – volume: 179 start-page: 1311 year: 2007 ident: BFnri3902_CR59 publication-title: J. Cell Biol. doi: 10.1083/jcb.200704042 contributor: fullname: PJ Wipff – volume: 515 start-page: 563 year: 2014 ident: BFnri3902_CR7 publication-title: Nature doi: 10.1038/nature14011 contributor: fullname: RS Herbst – volume: 197 start-page: 643 year: 2003 ident: BFnri3902_CR40 publication-title: J. Exp. Med. doi: 10.1084/jem.20021378 contributor: fullname: AY Savinov – volume: 70 start-page: 375 year: 2009 ident: BFnri3902_CR49 publication-title: Hum. Immunol. doi: 10.1016/j.humimm.2009.01.014 contributor: fullname: JK Mulligan – volume: 2 start-page: 251 year: 2007 ident: BFnri3902_CR10 publication-title: Annu. Rev. Pathol. doi: 10.1146/annurev.pathol.2.010506.134925 contributor: fullname: JA Nagy – volume: 56 start-page: 1111 year: 1996 ident: BFnri3902_CR17 publication-title: Cancer Res. contributor: fullname: AW Griffioen – volume: 106 start-page: 20847 year: 2009 ident: BFnri3902_CR78 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.0906481106 contributor: fullname: M Balsamo – volume: 18 start-page: 869 year: 2012 ident: BFnri3902_CR137 publication-title: Clin. Cancer Res. doi: 10.1158/1078-0432.CCR-11-2188 contributor: fullname: AD Steg – volume: 25 start-page: 30 year: 2009 ident: BFnri3902_CR2 publication-title: Trends Genet. doi: 10.1016/j.tig.2008.10.012 contributor: fullname: K Polyak – volume: 3 start-page: a005058 year: 2011 ident: BFnri3902_CR110 publication-title: Cold Spring Harb. Perspect. Biol. doi: 10.1101/cshperspect.a005058 contributor: fullname: P Lu – volume: 8 start-page: 471 year: 2002 ident: BFnri3902_CR97 publication-title: Clin. Cancer Res. contributor: fullname: T Onita – volume: 265 start-page: 106 year: 2013 ident: BFnri3902_CR67 publication-title: J. Neuroimmunol. doi: 10.1016/j.jneuroim.2013.09.011 contributor: fullname: K Ochs – volume: 103 start-page: 1204 year: 2008 ident: BFnri3902_CR73 publication-title: Circ. Res. doi: 10.1161/CIRCRESAHA.108.176826 contributor: fullname: M Gnecchi – volume: 15 start-page: 341 year: 2010 ident: BFnri3902_CR127 publication-title: J. Mammary Gland Biol. Neoplasia doi: 10.1007/s10911-010-9193-x contributor: fullname: AW Lund – volume: 1776 start-page: 160 year: 2007 ident: BFnri3902_CR9 publication-title: Biochim. Biophys. Acta contributor: fullname: K Castermans – volume: 330 start-page: 827 year: 2010 ident: BFnri3902_CR84 publication-title: Science doi: 10.1126/science.1195300 contributor: fullname: M Kraman – volume: 109 start-page: 2497 year: 2012 ident: BFnri3902_CR53 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.1113873109 contributor: fullname: L Pilotte – volume: 59 start-page: 268 year: 2004 ident: BFnri3902_CR107 publication-title: Allergy doi: 10.1111/j.1398-9995.2003.00442.x contributor: fullname: A Munitz – volume: 21 start-page: 524 year: 2015 ident: BFnri3902_CR36 publication-title: Nat. Med. doi: 10.1038/nm.3833 contributor: fullname: I Caruana – volume: 9 start-page: 685 year: 2003 ident: BFnri3902_CR11 publication-title: Nat. Med. doi: 10.1038/nm0603-685 contributor: fullname: RK Jain – volume: 86 start-page: 92 year: 2008 ident: BFnri3902_CR77 publication-title: Immunol. Cell Biol. doi: 10.1038/sj.icb.7100116 contributor: fullname: SN Byrne – volume: 139 start-page: 891 year: 2009 ident: BFnri3902_CR132 publication-title: Cell doi: 10.1016/j.cell.2009.10.027 contributor: fullname: KR Levental – volume: 42 start-page: 48 year: 1988 ident: BFnri3902_CR106 publication-title: Int. J. Cancer doi: 10.1002/ijc.2910420110 contributor: fullname: JR Starkey – volume: 66 start-page: 11238 year: 2006 ident: BFnri3902_CR99 publication-title: Cancer Res. doi: 10.1158/0008-5472.CAN-06-1278 contributor: fullname: EY Lin – volume: 186 start-page: 5549 year: 2011 ident: BFnri3902_CR62 publication-title: J. Immunol. doi: 10.4049/jimmunol.1003917 contributor: fullname: S Ichikawa – volume: 41 start-page: 49 year: 2014 ident: BFnri3902_CR111 publication-title: Immunity doi: 10.1016/j.immuni.2014.06.010 contributor: fullname: R Noy – volume: 23 start-page: 1104 year: 2010 ident: BFnri3902_CR41 publication-title: Mod. Pathol. doi: 10.1038/modpathol.2010.95 contributor: fullname: X Zang – volume: 450 start-page: 825 year: 2007 ident: BFnri3902_CR102 publication-title: Nature doi: 10.1038/nature06348 contributor: fullname: F Shojaei – volume: 88 start-page: 667 year: 1996 ident: BFnri3902_CR16 publication-title: Blood doi: 10.1182/blood.V88.2.667.bloodjournal882667 contributor: fullname: AW Griffioen – volume: 59 start-page: 267 year: 2010 ident: BFnri3902_CR50 publication-title: Cancer Immunol. Immunother. doi: 10.1007/s00262-009-0747-y contributor: fullname: JK Mulligan – volume: 6 start-page: 409 year: 2004 ident: BFnri3902_CR103 publication-title: Cancer Cell doi: 10.1016/j.ccr.2004.08.031 contributor: fullname: L Yang – volume: 2 start-page: 154 year: 2014 ident: BFnri3902_CR85 publication-title: Cancer Immunol. Res. doi: 10.1158/2326-6066.CIR-13-0027 contributor: fullname: LC Wang – volume: 116 start-page: 1955 year: 2006 ident: BFnri3902_CR25 publication-title: J. Clin. Invest. doi: 10.1172/JCI26532 contributor: fullname: M Loeffler – volume: 68 start-page: 8066 year: 2008 ident: BFnri3902_CR126 publication-title: Cancer Res. doi: 10.1158/0008-5472.CAN-08-0287 contributor: fullname: PC Maciag – volume: 81 start-page: 261 year: 2011 ident: BFnri3902_CR51 publication-title: Microvasc. Res. doi: 10.1016/j.mvr.2011.01.006 contributor: fullname: K Casos – volume: 190 start-page: 1175 year: 1999 ident: BFnri3902_CR88 publication-title: J. Exp. Med. doi: 10.1084/jem.190.8.1175 contributor: fullname: M Armant – volume: 521 start-page: 94 year: 2015 ident: BFnri3902_CR31 publication-title: Nature doi: 10.1038/nature14395 contributor: fullname: S Shalapour – volume: 12 start-page: 210 year: 2012 ident: BFnri3902_CR57 publication-title: Nat. Rev. Cancer doi: 10.1038/nrc3186 contributor: fullname: MA Swartz – volume: 74 start-page: 6796 year: 2014 ident: BFnri3902_CR116 publication-title: Cancer Res. doi: 10.1158/0008-5472.CAN-14-0079 contributor: fullname: A Textor – volume: 14 start-page: 38 year: 2014 ident: BFnri3902_CR144 publication-title: BMC Clin. Pathol. doi: 10.1186/1472-6890-14-38 contributor: fullname: AM Wirsing – volume: 33 start-page: 991 year: 2010 ident: BFnri3902_CR118 publication-title: J. Immunother. doi: 10.1097/CJI.0b013e3181f4c208 contributor: fullname: O Adotevi – volume: 3 start-page: 642 year: 2003 ident: BFnri3902_CR115 publication-title: Nat. Rev. Immunol. doi: 10.1038/nri1151 contributor: fullname: JL Gommerman – volume: 189 start-page: 832 year: 2014 ident: BFnri3902_CR145 publication-title: Am. J. Respir. Crit. Care Med. doi: 10.1164/rccm.201309-1611OC contributor: fullname: C Germain – volume: 18 start-page: 1262 year: 2012 ident: BFnri3902_CR69 publication-title: Nat. Med. doi: 10.1038/nm.2848 contributor: fullname: S Dulauroy – volume: 15 start-page: 2343 year: 2011 ident: BFnri3902_CR72 publication-title: J. Cell. Mol. Med. doi: 10.1111/j.1582-4934.2010.01215.x contributor: fullname: Z Han – volume: 4 start-page: 617 year: 2004 ident: BFnri3902_CR94 publication-title: Nat. Rev. Immunol. doi: 10.1038/nri1418 contributor: fullname: WC Parks – volume: 207 start-page: 681 year: 2010 ident: BFnri3902_CR55 publication-title: J. Exp. Med. doi: 10.1084/jem.20092465 contributor: fullname: JN Cohen – volume: 13 start-page: 2082 year: 2007 ident: BFnri3902_CR123 publication-title: Clin. Cancer Res. doi: 10.1158/1078-0432.CCR-06-2191 contributor: fullname: T Tsujino – volume: 70 start-page: 4431 year: 2013 ident: BFnri3902_CR135 publication-title: Cell. Mol. Life Sci. doi: 10.1007/s00018-013-1339-8 contributor: fullname: E Peranzoni – volume: 203 start-page: 551 year: 2004 ident: BFnri3902_CR13 publication-title: J. Pathol. doi: 10.1002/path.1543 contributor: fullname: M Furuya – volume: 6 start-page: 392 year: 2006 ident: BFnri3902_CR32 publication-title: Nat. Rev. Cancer doi: 10.1038/nrc1877 contributor: fullname: R Kalluri – volume: 107 start-page: 19461 year: 2010 ident: BFnri3902_CR46 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.1011748107 contributor: fullname: L Ma – volume: 157 start-page: 509 year: 2002 ident: BFnri3902_CR93 publication-title: J. Cell Biol. doi: 10.1083/jcb.200109098 contributor: fullname: Z Li – volume: 122 start-page: 899 year: 2012 ident: BFnri3902_CR33 publication-title: J. Clin. Invest. doi: 10.1172/JCI45817 contributor: fullname: H Salmon – volume: 104 start-page: 2224 year: 2004 ident: BFnri3902_CR27 publication-title: Blood doi: 10.1182/blood-2004-03-1109 contributor: fullname: C Murdoch – volume: 487 start-page: 500 year: 2012 ident: BFnri3902_CR136 publication-title: Nature doi: 10.1038/nature11183 contributor: fullname: R Straussman – volume: 39 start-page: 1 year: 2013 ident: BFnri3902_CR4 publication-title: Immunity doi: 10.1016/j.immuni.2013.07.012 contributor: fullname: DS Chen – volume: 112 start-page: 3650 year: 2008 ident: BFnri3902_CR60 publication-title: Blood doi: 10.1182/blood-2008-04-151753 contributor: fullname: J Ahamed – volume: 178 start-page: 1505 year: 2007 ident: BFnri3902_CR18 publication-title: J. Immunol. doi: 10.4049/jimmunol.178.3.1505 contributor: fullname: C Bouzin – volume: 456 start-page: 809 year: 2008 ident: BFnri3902_CR12 publication-title: Nature doi: 10.1038/nature07424 contributor: fullname: JI Greenberg – volume: 99 start-page: 1188 year: 2007 ident: BFnri3902_CR22 publication-title: J. Natl Cancer Inst. doi: 10.1093/jnci/djm064 contributor: fullname: D Nummer – volume: 13 start-page: 1382 year: 1999 ident: BFnri3902_CR104 publication-title: Genes Dev. doi: 10.1101/gad.13.11.1382 contributor: fullname: LM Coussens – volume: 112 start-page: 1142 year: 2003 ident: BFnri3902_CR124 publication-title: J. Clin. Invest. doi: 10.1172/JCI200318549 contributor: fullname: A Abramsson – volume: 8 start-page: 764 year: 2008 ident: BFnri3902_CR139 publication-title: Nat. Rev. Immunol. doi: 10.1038/nri2414 contributor: fullname: T Junt – volume: 28 start-page: e4 year: 2008 ident: BFnri3902_CR47 publication-title: Arterioscler. Thromb. Vasc. Biol. doi: 10.1161/ATVBAHA.107.158451 contributor: fullname: P Secchiero – volume: 2 start-page: 737 year: 2000 ident: BFnri3902_CR101 publication-title: Nat. Cell Biol. doi: 10.1038/35036374 contributor: fullname: G Bergers – volume: 7 start-page: 121 year: 2005 ident: BFnri3902_CR117 publication-title: Cancer Cell doi: 10.1016/j.ccr.2005.01.017 contributor: fullname: MG Achen – volume: 177 start-page: 3082 year: 2006 ident: BFnri3902_CR76 publication-title: J. Immunol. doi: 10.4049/jimmunol.177.5.3082 contributor: fullname: L Broderick – volume: 14 start-page: 447 year: 2014 ident: BFnri3902_CR142 publication-title: Nat. Rev. Immunol. doi: 10.1038/nri3700 contributor: fullname: C Pitzalis – volume: 54 start-page: 262 year: 2011 ident: BFnri3902_CR63 publication-title: Hepatology doi: 10.1002/hep.24352 contributor: fullname: FA Schildberg – volume: 11 start-page: 526 year: 2007 ident: BFnri3902_CR133 publication-title: Cancer Cell doi: 10.1016/j.ccr.2007.04.020 contributor: fullname: JD Shields – volume: 100 start-page: 2 year: 2002 ident: BFnri3902_CR131 publication-title: Int. J. Cancer doi: 10.1002/ijc.10481 contributor: fullname: C LeBedis – volume: 14 start-page: 28 year: 2008 ident: BFnri3902_CR19 publication-title: Nat. Med. doi: 10.1038/nm1699 contributor: fullname: RJ Buckanovich – volume: 111 start-page: 14776 year: 2014 ident: BFnri3902_CR30 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.1416498111 contributor: fullname: M Ammirante – volume: 4 start-page: e7965 year: 2009 ident: BFnri3902_CR26 publication-title: PLoS ONE doi: 10.1371/journal.pone.0007965 contributor: fullname: D Liao – volume: 470 start-page: 548 year: 2011 ident: BFnri3902_CR28 publication-title: Nature doi: 10.1038/nature09707 contributor: fullname: W Tan – volume: 25 start-page: 719 year: 2014 ident: BFnri3902_CR37 publication-title: Cancer Cell doi: 10.1016/j.ccr.2014.04.005 contributor: fullname: BC Ozdemir – volume: 13 start-page: 1211 year: 2007 ident: BFnri3902_CR105 publication-title: Nat. Med. doi: 10.1038/nm1649 contributor: fullname: L Soucek – volume: 7 start-page: 211 year: 2005 ident: BFnri3902_CR109 publication-title: Cancer Cell doi: 10.1016/j.ccr.2005.02.013 contributor: fullname: F Balkwill – volume: 34 start-page: 1 year: 2010 ident: BFnri3902_CR61 publication-title: J. Autoimmun. doi: 10.1016/j.jaut.2009.08.008 contributor: fullname: G Tiegs – volume: 129 start-page: 2651 year: 2011 ident: BFnri3902_CR64 publication-title: Int. J. Cancer doi: 10.1002/ijc.25920 contributor: fullname: W Zhao – volume: 94 start-page: 182 year: 2014 ident: BFnri3902_CR65 publication-title: Lab. Invest. doi: 10.1038/labinvest.2013.139 contributor: fullname: W Zhao – volume: 174 start-page: 5215 year: 2005 ident: BFnri3902_CR75 publication-title: J. Immunol. doi: 10.4049/jimmunol.174.9.5215 contributor: fullname: M Ahmadzadeh – volume: 515 start-page: 568 year: 2014 ident: BFnri3902_CR8 publication-title: Nature doi: 10.1038/nature13954 contributor: fullname: PC Tumeh – volume: 515 start-page: 558 year: 2014 ident: BFnri3902_CR6 publication-title: Nature doi: 10.1038/nature13904 contributor: fullname: T Powles – volume: 103 start-page: 12493 year: 2006 ident: BFnri3902_CR100 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.0601807103 contributor: fullname: H Nozawa – volume: 72 start-page: 3997 year: 2012 ident: BFnri3902_CR148 publication-title: Cancer Res. doi: 10.1158/0008-5472.CAN-12-1377 contributor: fullname: A Cipponi – volume: 20 start-page: 815 year: 2011 ident: BFnri3902_CR66 publication-title: Dev. Cell doi: 10.1016/j.devcel.2011.04.019 contributor: fullname: LE Olson – volume: 453 start-page: 410 year: 2008 ident: BFnri3902_CR14 publication-title: Nature doi: 10.1038/nature06868 contributor: fullname: J Hamzah – volume: 314 start-page: 15 year: 2003 ident: BFnri3902_CR125 publication-title: Cell Tissue Res. doi: 10.1007/s00441-003-0745-x contributor: fullname: H Gerhardt – volume: 2 start-page: a006494 year: 2012 ident: BFnri3902_CR108 publication-title: Cold Spring Harb. Perspect. Med. doi: 10.1101/cshperspect.a006494 contributor: fullname: A Zumsteg – volume: 5 start-page: 3989 year: 2014 ident: BFnri3902_CR56 publication-title: Nat. Commun. doi: 10.1038/ncomms4989 contributor: fullname: BA Tamburini – volume: 91 start-page: 1071 year: 2011 ident: BFnri3902_CR15 publication-title: Physiol. Rev. doi: 10.1152/physrev.00038.2010 contributor: fullname: S Goel – volume: 13 start-page: 739 year: 2013 ident: BFnri3902_CR24 publication-title: Nat. Rev. Cancer doi: 10.1038/nrc3581 contributor: fullname: JE Talmadge – volume: 164 start-page: 2947 year: 2000 ident: BFnri3902_CR91 publication-title: J. Immunol. doi: 10.4049/jimmunol.164.6.2947 contributor: fullname: AN Vallejo – volume: 15 start-page: 2148 year: 2009 ident: BFnri3902_CR119 publication-title: Clin. Cancer Res. doi: 10.1158/1078-0432.CCR-08-1332 contributor: fullname: JS Ko – volume: 5 start-page: 1640 year: 2006 ident: BFnri3902_CR121 publication-title: Cancer Biol. Ther. doi: 10.4161/cbt.5.12.3354 contributor: fullname: H Sugimoto – volume: 4 start-page: 839 year: 2004 ident: BFnri3902_CR120 publication-title: Nat. Rev. Cancer doi: 10.1038/nrc1477 contributor: fullname: MM Mueller – volume: 71 start-page: 5678 year: 2011 ident: BFnri3902_CR147 publication-title: Cancer Res. doi: 10.1158/0008-5472.CAN-11-0431 contributor: fullname: L Martinet – volume: 169 start-page: 3581 year: 2002 ident: BFnri3902_CR43 publication-title: J. Immunol. doi: 10.4049/jimmunol.169.7.3581 contributor: fullname: MM Mazanet – volume: 4 start-page: 2516 year: 2013 ident: BFnri3902_CR134 publication-title: Nat. Commun. doi: 10.1038/ncomms3516 contributor: fullname: VP Chauhan – volume: 33 start-page: 3117 year: 2003 ident: BFnri3902_CR42 publication-title: Eur. J. Immunol. doi: 10.1002/eji.200324270 contributor: fullname: N Rodig – volume: 339 start-page: 286 year: 2013 ident: BFnri3902_CR95 publication-title: Science doi: 10.1126/science.1232227 contributor: fullname: LM Coussens – volume: 56 start-page: 4625 year: 1996 ident: BFnri3902_CR96 publication-title: Cancer Res. contributor: fullname: RD Leek – volume: 57 start-page: 138 year: 1999 ident: BFnri3902_CR98 publication-title: Oncology doi: 10.1159/000012021 contributor: fullname: I Takanami
SSID	ssj0016174
Score	2.6976564
SecondaryResourceType	review_article
Snippet	Key Points Non-haematopoietic stromal cells in the tumour microenvironment actively interact with infiltrating leukocytes. Emerging evidence also suggests that... A dynamic and mutualistic interaction between tumour cells and the surrounding stroma promotes the initiation, progression, metastasis and chemoresistance of...
SourceID	proquest gale crossref pubmed springer
SourceType	Aggregation Database Index Database Publisher
StartPage	669
SubjectTerms	631/250/2520 631/250/580 631/67/327 Adipocytes Animals Antigens Biomedicine Cancer Care and treatment Cell Communication Cell Movement Cytotoxicity, Immunologic Dendritic cells Extracellular matrix Extracellular Matrix - physiology Fibroblasts Fibroblasts - physiology Growth factors Health aspects Humans Immunology Immunotherapy Leukocytes Leukocytes - physiology Lymphatic system Medical prognosis Mesenchymal Stromal Cells - physiology review-article Stem cells Stromal Cells - immunology Tumor Microenvironment Tumors
Title	Immunological hallmarks of stromal cells in the tumour microenvironment
URI	https://link.springer.com/article/10.1038/nri3902 https://www.ncbi.nlm.nih.gov/pubmed/26471778 https://www.proquest.com/docview/1767343691 https://search.proquest.com/docview/1727435656 https://search.proquest.com/docview/1773830081
Volume	15
hasFullText	1
inHoldings	1
isFullTextHit
isPrint
link	http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3PT51AEJ5UTZteTGt_0apdmyY9EYFZ2OXUqNFqE01ja_JuZFmgMc0DC7xD_3tnHsvrw4MXDjCEZXZn95ud_WYAPuugSjUWia-1iX1JAN9PbRD4BH5LqfJSFiEThS-vkvMb-X0Wz9yGW-eOVY5z4nKiLhrLe-SHoUoUSkzS8OvdX5-rRnF01ZXQ2ICtKJQcpt06Pr36cb2KIyRDHuZQKkmfRxxos5wU_LBub8nfjybr0cNZeW1ZehAnXS4_Zy9g2-FGcTR09Et4UtY78HSoJPlvB55duhj5K_h2wZSPcU4TXCxlbto_nWgq0fVtM6ebvF3fidtaEPwT_YLc_1bM-WjeGu_tNdycnf46OfdduQTfxkr19H9GVWEVGkI8lvyeksANygQrzXScglyRSts4yfNAK9RkjFFoDWKhiiRNK0R8A5t1U5fvQOR5bCPN2jNWVhEaFlaY2wLzwMSxB2JUWnY3ZMXIltFs1JnTqwcfWZnZQOdc2VF2JJn7i1GgPfi0lOAsFDUfc_ltFl2XXfy8ngh9cUJV07fGGscaoHZy4qqJ5O5EkszETh-PvZo5M-2y_4PKg4PVY36Tj57VZbNgGXLckXHvYzKkUWR45cHbYcSs9EKIk1xmRQ04GIfQWgOmSnv_eCM_wHPCa_FAhdyFzb5dlHuEifp8HzbUTNFVn4T7zgjuAcxxCRc
link.rule.ids	315,786,790,12083,12250,21416,27955,27956,31752,31753,33299,33300,33777,33778,43343,43612,43838,74100,74369,74657
linkProvider	ProQuest
linkToHtml	http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Nb9QwEB1BER8XBIVCoFAXIXGKmmSc2DmhqqLsQrcHaKXeIsdJUIU2KUn2wL9nJvEumx56jSeKM_bYbzzzPAAfdVClGovE19rEviSA76c2CHwCv6VUeSmLkInCi_Nkdim_XcVX7sCtc2mV6zVxWKiLxvIZ-VGoEoUSkzT8fPPH56pRHF11JTTuwwNqCrmCgT7ZpHgwdB-iylJJ-jjiSJrlK8GP6vaavP1oshvdXpO3NqVbUdJh8zl9Bk8dahTH4zA_h3tlvQsPxzqSf3fh0cJFyF_A1zkTPtYrmuBSKUvT_u5EU4mub5slPeTD-k5c14LAn-hX5Py3YsmJeVust5dwefrl4mTmu2IJvo2V6un_jKrCKjSEdyx5PSVBG5QJVprJOAU5IpW2cZLngVaoyRSj0BrEQhVJmlaIuAc7dVOXr0HkeWwjzdozVlYRGhZWmNsC88DEsQdirbTsZrwTIxti2agzp1cPDliZ2Ujm3FhRdiyZ-YtRoD34MEjwHRQ1J7n8Mquuy-Y_f0yEPjmhqulbY43jDFA_-dqqieT-RJKMxE6b16OaOSPtsv9TyoPDTTO_yYlnddmsWIbcdmTUe5cMaRQZXHnwapwxG70Q3iSHWVEHDtdTaKsDU6W9ubuTB_B4drE4y87m59_fwhNCbvFIityHnb5dle8IHfX5-8EE_gEl5wi1
linkToPdf	http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Bb5VAEN5ojY0XU6tWtLZbY-KJPGAWdjk1Te2zT21j1Ca9kWVhTWMeVOAd_PfOwPJ89NArDGSY3dn9hplvh7H3KrCpgiLxldKxLxDg-6kJAh_BbylkXooiJKLwxWVyfiU-X8fXrv6pdWWV45rYL9RFbegf-SyUiQQBSRrOrCuL-PZxfnz7x6cOUpRpde00HrJHkuSINX66LvcgGN9nmIUUqAjAQKCl48FnVXODkX802Znurs8bG9SdjGm_Ec132FOHIPnJMOTP2IOy2mWPh56Sf3fZ9oXLlj9nnxZE_hhXN05tU5a6-d3y2vK2a-olXqQf9y2_qTgCQd6tlvh2vqQivQ0G3At2NT_7eXruu8YJvoml7PD7tLShDTViH4MRUIkwB0QCVhExp8CgxCoTJ3keKAkK3TIKjQYoZJGkqQWAl2yrqqvyFeN5HptIkfW0ETYCTcISclNAHug49hgfjZbdDudjZH1eG1Tm7OqxQzJmNhA71x6VnQhiAUMUKI-96yXoPIqKRvaXXrVttvjxfSL0wQnZumu00Y4_gHrSEVYTyf2JJDqMmd4eRzVzDttm_6eXx47Wt-lJKkKrynpFMhjCAyHg-2TQokBAy2N7w4xZ2wWxJwbPEhU4GqfQhgJTo72-X8lDto2zP_u6uPzyhj1BEBcP_Mh9ttU1q_ItAqUuP-g94B_pNQzz
openUrl	ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Immunological+hallmarks+of+stromal+cells+in+the+tumour+microenvironment&rft.jtitle=Nature+reviews.+Immunology&rft.au=Cremasco%2C+Viviana&rft.au=Astarita%2C+Jillian+L&rft.date=2015-11-01&rft.pub=Nature+Publishing+Group&rft.issn=1474-1733&rft.eissn=1474-1741&rft.spage=669&rft_id=info:doi/10.1038%2Fnri3902&rft.externalDBID=ISR&rft.externalDocID=A433483208
thumbnail_l	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1474-1733&client=summon
thumbnail_m	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1474-1733&client=summon
thumbnail_s	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1474-1733&client=summon