Unsuccessful treatment outcome and associated risk factors. A prospective study of DR-TB patients from a high burden country, Pakistan

• Published in: PloS one Vol. 18; no. 8; p. e0287966
• Main Authors: Massud, Asif, Khan, Amer Hayat, Syed Sulaiman, Syed Azhar, Ahmad, Nafees, Shafqat, Muhammad, Ming, Long Chiau
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 10.08.2023
• Subjects: Adult; Antitubercular Agents - therapeutic use; Biology and Life Sciences; Care and treatment; Cavitation; Clinical outcomes; Communicable diseases; Data collection; Diagnosis; Drug dosages; Drug resistance; Drug resistance in microorganisms; Evaluation; Female; Health risks; Humans; Infectious diseases; Laboratories; Male; Medical diagnosis; Medical research; Medicine and Health Sciences; Medicine, Experimental; Middle Aged; Mortality; Observational studies; Pakistan; Pakistan - epidemiology; Patient outcomes; Patients; People and Places; Physical Sciences; Prospective Studies; Regression analysis; Research and Analysis Methods; Retrospective Studies; Risk Factors; Statistical analysis; Treatment Outcome; Tuberculosis; Tuberculosis - drug therapy; Tuberculosis - epidemiology; Tuberculosis, Multidrug-Resistant - drug therapy; World health; Young Adult; Pakistan; India

Tuberculosis (TB), a curable and preventable infectious disease, becomes difficult to treat if resistance against most effective and tolerable first line anti-TB drugs is developed. The objective of the present study was to evaluate the treatment outcomes and predictors of poor outcomes among drug-r...