Snake venom toxins: toxicity and medicinal applications

• Published in: Applied microbiology and biotechnology Vol. 100; no. 14; pp. 6165 - 6181
• Main Authors: Chan, Yau Sang, Cheung, Randy Chi Fai, Xia, Lixin, Wong, Jack Ho, Ng, Tzi Bun, Chan, Wai Yee
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.07.2016; Springer; Springer Nature B.V
• Subjects: Alzheimer's disease; analgesic effect; Analgesics; Analgesics - analysis; Analgesics - pharmacology; Analysis; Animals; Anti-Infective Agents - analysis; Anti-Infective Agents - pharmacology; Anticoagulants - analysis; Anticoagulants - pharmacology; Antineoplastic Agents - analysis; Antineoplastic Agents - pharmacology; Biomedical and Life Sciences; Biotechnology; Cancer; Cardiac function; Clinical Trials as Topic; Cytotoxicity; Enzymatic activity; enzyme activity; Enzymes; Health aspects; Humans; Life Sciences; Lipids; Medical research; Medicine; Microbial Genetics and Genomics; Microbiology; Mini-Review; Neurotoxicity; people; Peptides; Peptides - analysis; poisoning; Poisons; Protein Conformation; Proteins; Proteins - analysis; Reptiles & amphibians; Snake bites; Snake venoms; Snake Venoms - chemistry; Snake Venoms - pharmacology; Snakes; Studies; Therapy; Toxicity; Toxins; Venom; venoms; Toxin; Therapeutic; Snake; Venom

Snake venoms are complex mixtures of small molecules and peptides/proteins, and most of them display certain kinds of bioactivities. They include neurotoxic, cytotoxic, cardiotoxic, myotoxic, and many different enzymatic activities. Snake envenomation is a significant health issue as millions of sna...