Antifungal activity of the lipopeptides produced by Bacillus amyloliquefaciens anti-CA against Candida albicans isolated from clinic

• Published in: Applied microbiology and biotechnology Vol. 97; no. 16; pp. 7141 - 7150
• Main Authors: Song, Bo, Rong, Yan-Jun, Zhao, Ming-Xin, Chi, Zhen-Ming
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.08.2013; Springer; Springer Nature B.V
• Subjects: Amino acids; Analysis; Antifungal activity; Antifungal Agents; Antifungal Agents - isolation & purification; Antifungal Agents - pharmacology; antifungal properties; Antimicrobial agents; Bacillus; Bacillus - chemistry; Bacillus amyloliquefaciens; Bacteria; Biological activity; Biomedical and Life Sciences; Biotechnological Products and Process Engineering; Biotechnology; Candida albicans; Candida albicans - drug effects; Candida albicans - isolation & purification; Candida tropicalis; Candida tropicalis - drug effects; Candidiasis; Candidiasis - microbiology; carbon; chemistry; Clinics; Cluster Analysis; Culture Media; Culture Media - chemistry; Culture Media - economics; DNA, Bacterial; DNA, Bacterial - chemistry; DNA, Bacterial - genetics; DNA, Ribosomal; DNA, Ribosomal - chemistry; DNA, Ribosomal - genetics; drug effects; Drug resistance; economics; Enzymes; Fatty acids; Flour; Fungi; genetics; isolation & purification; Life Sciences; lipopeptides; Lipopeptides - isolation & purification; Lipopeptides - pharmacology; Metschnikowia; Metschnikowia - drug effects; Microbial Genetics and Genomics; Microbiology; Microorganisms; Molecular Sequence Data; Pathogens; Peptides; pharmacology; Phylogeny; Proteases; proteinases; protoplasts; RNA, Ribosomal, 16S; RNA, Ribosomal, 16S - genetics; Saccharomyces cerevisiae; Saccharomyces cerevisiae - drug effects; Sequence Analysis, DNA; Soybean; soybean meal; Soybeans; Studies; Wheat; wheat flour; Yarrowia; Yarrowia - drug effects; Yarrowia lipolytica; Yeast; yeasts; Fungal pathogen; Surfactin; Lipopeptide

The bacterium Bacillus amyloliquefaciens anti-CA isolated from mangrove system was found to be able to actively kill Candida albicans isolated from clinic. The bacterial strain anti-CA could produce high level of bioactive substance, amylase and protease in the cheap medium containing 2.0 % soybean...