Serological response to vaccination in post-acute sequelae of COVID

• Published in: BMC infectious diseases Vol. 23; no. 1; p. 97
• Main Authors: Joung, Sandy, Weber, Brittany, Wu, Min, Liu, Yunxian, Tang, Amber B, Driver, Matthew, Sternbach, Sarah, Wynter, Timothy, Hoang, Amy, Barajas, Denisse, Kao, Yu Hung, Khuu, Briana, Bravo, Michelle, Masoom, Hibah, Tran, Teresa, Sun, Nancy, Botting, Patrick G, Claggett, Brian L, Prostko, John C, Frias, Edwin C, Stewart, James L, Robertson, Jackie, Kwan, Alan C, Torossian, Mariam, Pedraza, Isabel, Sterling, Carina, Goldzweig, Caroline, Oft, Jillian, Zabner, Rachel, Fert-Bober, Justyna, Ebinger, Joseph E, Sobhani, Kimia, Cheng, Susan, Le, Catherine N
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 16.02.2023; BioMed Central; BMC
• Subjects: ACE2; Adults; Analysis; Angiotensin; Angiotensin-Converting Enzyme 2; Anti-spike antibody; Antibodies; Antibodies, Viral; Binding; Class switching; Cohort analysis; Comorbidity; Comparative analysis; Complications; COVID-19 - prevention & control; COVID-19 vaccines; COVID-19 Vaccines - immunology; Demographic variables; Disease Progression; Dosage and administration; Drug dosages; Enzymes; Health aspects; Health care; Humans; Humoral immunity; Immune activation; Immune response; Immune response (humoral); Immune system; Immunity; Immunization; Immunoglobulin G; Immunoglobulin M; Infections; Longitudinal studies; Missing data; Nucleocapsids; Patients; Peptidyl-dipeptidase A; Pharmaceutical industry; Phenotypes; Physiology, Pathological; Plasma; Post-Acute COVID-19 Syndrome - immunology; Post-acute sequelae; Regression analysis; Review boards; SARS-CoV-2; Serological response; Serology; Severe acute respiratory syndrome coronavirus 2; Vaccination; Vaccines; United States; SARS-CoV-2; Immune activation; Post-acute sequelae; Anti-spike antibody; Serological response

Individuals with post-acute sequelae of COVID (PASC) may have a persistence in immune activation that differentiates them from individuals who have recovered from COVID without clinical sequelae. To investigate how humoral immune activation may vary in this regard, we compared patterns of vaccine-pr...