Disseminated vaccine-strain varicella-zoster virus reactivation in an adolescent with secondary immunodeficiency: a case report and literature review

• Published in: BMC infectious diseases Vol. 24; no. 1; pp. 1296 - 6
• Main Authors: Fashina, Oluwatomini A., Chuang, Tony M., Galardy, Paul J., Huskins, W. Charles, Levy, Emily R., Streck, Nicholas T., Chakraborty, Rana
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 14.11.2024; BioMed Central; BMC
• Subjects: Acyclovir; Acyclovir - therapeutic use; Adolescent; Adolescents; Antiviral Agents - therapeutic use; Case studies; Chemotherapy; Chicken pox; Chickenpox; Chickenpox Vaccine - administration & dosage; Chickenpox Vaccine - adverse effects; Children; Complications; Disease prevention; Disease resistance; Diseases; Disseminated; Encephalitis; Exanthema; Female; Genotyping; Health aspects; Hematology; Hepatitis; Herpes viruses; Herpes zoster; Herpes Zoster - virology; Herpesvirus 3, Human - genetics; Herpesvirus 3, Human - immunology; Hodgkin Disease - drug therapy; Hodgkin Disease - virology; Hospitalization; Humans; Immunization; Immunocompromised Host; Immunocompromised hosts; Immunodeficiency; Infections; Lesions; Literature reviews; Lymphoma; Meningitis; Migraine; Neutropenia; Oncology; Patient outcomes; Patients; Pediatric; Pediatrics; Pneumonia; Pneumonitis; Polymerase chain reaction; Relapse; Risk factors; Surveys; Teenagers; Vaccine-strain; Vaccines; Varicella; Varicella Zoster Virus Infection - virology; Varicella-zoster virus; Virus Activation; Viruses; Youth; United States; United States > US; Minnesota; Disseminated; Vaccine-strain; Varicella-zoster virus; Pediatric; Adolescent; Immunodeficiency

Routine childhood immunization against varicella-zoster virus has led to a dramatic reduction in the incidence of primary varicella. However, there are rare, yet significant cases reported of reactivated Oka-strain varicella, primarily in immunocompromised hosts. A 16-year-old female with Hodgkin�...