Transcriptome‑wide piRNA profiling in human gastric cancer

• Published in: Oncology reports Vol. 41; no. 5; pp. 3089 - 3099
• Main Authors: Lin, Xiandong, Xia, Yan, Hu, Dan, Mao, Qiao, Yu, Zongyang, Zhang, Hejun, Li, Chao, Chen, Gang, Liu, Fen, Zhu, Weifeng, Shi, Yi, Zhang, Huihao, Zheng, Jianming, Sun, Tao, Xu, Jianying, Chao, Herta, Zheng, Xiongwei, Luο, Xingguang
• Format: Journal Article
• Language: English
• Published: Greece Spandidos Publications 01.05.2019; Spandidos Publications UK Ltd; D.A. Spandidos
• Subjects: Adult; Aged; Aging; Alzheimer's disease; Animals; Breast cancer; Cancer; Cancer research; Causes of; Cohort Studies; Deoxyribonucleic acid; DNA; DNA Transposable Elements - genetics; Female; Gastric cancer; Gene expression; Gene Expression Profiling - methods; Gene Expression Regulation, Neoplastic; Genes; Genetic aspects; Genetic research; Genomes; Genomics; Hospitals; Humans; Male; Middle Aged; Oligonucleotide Array Sequence Analysis - methods; Pathogenesis; Polymorphism, Single Nucleotide - genetics; Protein expression; Proteins; RNA; RNA, Small Interfering - genetics; RNA, Small Interfering - metabolism; Stem cells; Stomach - pathology; Stomach cancer; Stomach Neoplasms - genetics; Stomach Neoplasms - pathology; Studies; Transcriptome - genetics; Transposons; Tumors

Piwi‑interacting RNAs (piRNAs) comprise the largest class of non‑coding RNAs. They represent a molecular feature shared by all non‑aging biological systems, including germline and somatic cancer stem cells, which display an indefinite capacity of renewal and proliferation and are potentially immorta...