Comparative secretome of ovarian serous carcinoma: Gelsolin in the spotlight

• Published in: Oncology letters Vol. 13; no. 6; pp. 4965 - 4973
• Main Authors: Pierredon, Sandra, Ribaux, Pascale, Tille, Jean-Christophe, Petignat, Patrick, Cohen, Marie
• Format: Journal Article
• Language: English
• Published: Greece Spandidos Publications 01.06.2017; Spandidos Publications UK Ltd; D.A. Spandidos
• Subjects: Antigens; Binding proteins; Cancer therapies; Care and treatment; Chemotherapy; Dehydrogenases; Development and progression; Disease; Gene expression; Genetic aspects; Gynecology; Health aspects; Heat shock proteins; Immunoassay; Insulin; Insulin-like growth factors; Keratin; Metastasis; Molecular weight; Mortality; Oncology; Ovarian cancer; Patients; Physiology; Proteomics; Tumors; United Kingdom > UK; United States > US; secretome; gelsolin; ovarian cancer; marker; target

Ovarian cancer is one of the most common types of reproductive cancer, and has the highest mortality rate amongst gynecological cancer subtypes. The majority of ovarian cancers are diagnosed at an advanced stage, resulting in a five-year survival rate of ~30%. Early diagnosis of ovarian cancer has i...