Targeted Drug Delivery — From Magic Bullet to Nanomedicine: Principles, Challenges, and Future Perspectives

• Published in: Journal of multidisciplinary healthcare Vol. 14; pp. 1711 - 1724
• Main Authors: Tewabe, Ashagrachew, Abate, Atlaw, Tamrie, Manaye, Seyfu, Abyou, Abdela Siraj, Ebrahim
• Format: Journal Article
• Language: English
• Published: New Zealand Dove Medical Press Limited 01.01.2021; Taylor & Francis Ltd; Dove; Dove Medical Press
• Subjects: carriers; Drug delivery systems; Drug dosages; Drug therapy; Drugs; Ehrlich, Paul (German bacteriologist); Enzymes; Health aspects; nanoparticles; nanosomes; Pharmaceuticals; Pharmacokinetics; Physiology; Polymers; Principles; Review; targeting; Toxicity; Tumors; Vehicles; Ethiopia; nanosomes; targeting; carriers; nanoparticles; polymers

Nanomedicine is an advanced version of Paul Ehrlich's "magic bullet" concept. Targeted drug delivery is a system of specifying the drug moiety directly into its targeted body area (organ, cellular, and subcellular level of specific tissue) to overcome the aspecific toxic effect of con...