Comparison of plasma responses in human subjects after the ingestion of 3R,3R′-zeaxanthin dipalmitate from wolfberry (Lycium barbarum) and non-esterified 3R,3R′-zeaxanthin using chiral high-performance liquid chromatography

• Published in: British journal of nutrition Vol. 91; no. 5; pp. 707 - 713
• Main Authors: Breithaupt, Dietmar E., Weller, Philipp, Wolters, Maike, Hahn, Andreas
• Format: Journal Article
• Language: English
• Published: Cambridge, UK Cambridge University Press 01.05.2004
• Subjects: 3′R-zeaxanthin; administration & dosage; Adult; analogs & derivatives; beta Carotene; beta Carotene - administration & dosage; beta Carotene - analogs & derivatives; beta Carotene - blood; beta Carotene - metabolism; Bioavailability; Biological and medical sciences; blood; breakfast; chemistry; Chiral analysis; Chromatography, High Pressure Liquid; Chromatography, High Pressure Liquid - methods; Cross-Over Studies; diet; Dietary Supplements; elderly; fasting; Feeding. Feeding behavior; Female; Fundamental and applied biological sciences. Psychology; high performance liquid chromatography; Humans; Ingestion; Liquid chromatography; Liquid chromatography–atmospheric pressure chemical ionisation-mass spectrometry; lutein; Lycium; Lycium - chemistry; Lycium barbarum; Macular degeneration; Male; Mass Spectrometry; Mass Spectrometry - methods; metabolism; methods; Palmitates; Palmitates - administration & dosage; Palmitates - metabolism; Plant Extracts; Plant Extracts - administration & dosage; Plant Extracts - metabolism; Plasma carotenoid response; risk; Single-Blind Method; Stereoisomerism; t-test; Vertebrates: anatomy and physiology, studies on body, several organs or systems; volunteers; Xanthophylls; yogurt; zeaxanthin; Zeaxanthin esters; Zeaxanthins; 3R,3′R-zeaxanthin; Plasma carotenoid response; Chiral analysis; Liquid chromatography–atmospheric pressure chemical ionisation-mass spectrometry; Zeaxanthin esters; Human; 3R,3'R-zeaxanthin: Zeaxanthin esters: Plasma carotenoid response: Chiral analysis: Liquid chromatography-atmospheric pressure chemical ionisation-mass spectrometry; Liquid; Zeaxanthin; Vertebrata; Mammalia; Physical performance; Ingestion

Age-related macular degeneration (AMD) is one of the most common eye diseases of elderly individuals. It has been suggested that lutein and zeaxanthin may reduce the risk for AMD. Information concerning the absorption of non-esterified or esterified zeaxanthin is rather scarce. Furthermore, the form...