Interatrial shunt devices for heart failure with normal ejection fraction: a technology update

Heart failure with normal ejection fraction (HeFNEF) accounts for ~50% of heart failure admissions. Its pathophysiology and diagnostic criteria are yet to be defined clearly which may hinder the search for effective treatments. The clinical hallmark of HeFNEF is exertional breathlessness, often due...

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Published inMedical devices (Auckland, N.Z.) Vol. 10; pp. 123 - 132
Main Authors Cuthbert, Joseph J, Pellicori, Pierpaolo, Clark, Andrew L
Format Journal Article Book Review
LanguageEnglish
Published New Zealand Dove Medical Press Limited 01.01.2017
Taylor & Francis Ltd
Dove Medical Press
Subjects
Anticoagulants
Cardiology
Cardiovascular disease
Care and treatment
Congenital diseases
Defects
Heart failure
Heart failure with normal ejection fraction. Heart failure with normal ejection fraction. Interatrial shunt devices. IASD. V-Wave. Device therapy
Hypertension
Medical prognosis
Mortality
Pulmonary arteries
Quality of life
Review
Risk factors
Surgical anastomosis
Veins & arteries
Workloads
New York
United States > US
device therapy
V-Wave
preserved EF
HeFPEF
review
HFpEF
HeFNEF
IASD
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Abstract Heart failure with normal ejection fraction (HeFNEF) accounts for ~50% of heart failure admissions. Its pathophysiology and diagnostic criteria are yet to be defined clearly which may hinder the search for effective treatments. The clinical hallmark of HeFNEF is exertional breathlessness, often due to an abnormal increase in left atrial pressure during exercise. Creation of an interatrial communication to offload the left atrium is a possible therapeutic approach. There are two percutaneously delivered devices currently under investigation which are discussed in this review.
AbstractList Heart failure with normal ejection fraction (HeFNEF) accounts for ~50% of heart failure admissions. Its pathophysiology and diagnostic criteria are yet to be defined clearly which may hinder the search for effective treatments. The clinical hallmark of HeFNEF is exertional breathlessness, often due to an abnormal increase in left atrial pressure during exercise. Creation of an interatrial communication to offload the left atrium is a possible therapeutic approach. There are two percutaneously delivered devices currently under investigation which are discussed in this review.
Joseph J Cuthbert, Pierpaolo Pellicori, Andrew L Clark Department of Cardiology, Hull York Medical School, Hull and East Yorkshire Medical Research and Teaching Centre, Castle Hill Hospital, Cottingham, Kingston upon Hull, UK Abstract: Heart failure with normal ejection fraction (HeFNEF) accounts for ~50% of heart failure admissions. Its pathophysiology and diagnostic criteria are yet to be defined clearly which may hinder the search for effective treatments. The clinical hallmark of HeFNEF is exertional breathlessness, often due to an abnormal increase in left atrial pressure during exercise. Creation of an interatrial communication to offload the left atrium is a possible therapeutic approach. There are two percutaneously delivered devices currently under investigation which are discussed in this review. Keywords: IASD, V-Wave, device therapy, HeFNEF, review, preserved EF, HeFPEF, HFpEF
Heart failure with normal ejection fraction (HeFNEF) accounts for ~50% of heart failure admissions. Its pathophysiology and diagnostic criteria are yet to be defined clearly which may hinder the search for effective treatments. The clinical hallmark of HeFNEF is exertional breathlessness, often due to an abnormal increase in left atrial pressure during exercise. Creation of an interatrial communication to offload the left atrium is a possible therapeutic approach. There are two percutaneously delivered devices currently under investigation which are discussed in this review. Keywords: IASD, V-Wave, device therapy, HeFNEF, review, preserved EF, HeFPEF, HFpEF
Audience Academic
Author Clark, Andrew L
Cuthbert, Joseph J
Pellicori, Pierpaolo
AuthorAffiliation Department of Cardiology, Hull York Medical School, Hull and East Yorkshire Medical Research and Teaching Centre, Castle Hill Hospital, Cottingham, Kingston upon Hull, UK
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  surname: Pellicori
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  organization: Department of Cardiology, Hull York Medical School, Hull and East Yorkshire Medical Research and Teaching Centre, Castle Hill Hospital, Cottingham, Kingston upon Hull, UK
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  surname: Clark
  fullname: Clark, Andrew L
  organization: Department of Cardiology, Hull York Medical School, Hull and East Yorkshire Medical Research and Teaching Centre, Castle Hill Hospital, Cottingham, Kingston upon Hull, UK
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2017 Cuthbert et al. This work is published and licensed by Dove Medical Press Limited 2017
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Keywords device therapy
V-Wave
preserved EF
HeFPEF
review
HFpEF
HeFNEF
IASD
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Snippet Heart failure with normal ejection fraction (HeFNEF) accounts for ~50% of heart failure admissions. Its pathophysiology and diagnostic criteria are yet to be...
Joseph J Cuthbert, Pierpaolo Pellicori, Andrew L Clark Department of Cardiology, Hull York Medical School, Hull and East Yorkshire Medical Research and...
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StartPage 123
SubjectTerms Anticoagulants
Cardiology
Cardiovascular disease
Care and treatment
Congenital diseases
Defects
Heart failure
Heart failure with normal ejection fraction. Heart failure with normal ejection fraction. Interatrial shunt devices. IASD. V-Wave. Device therapy
Hypertension
Medical prognosis
Mortality
Pulmonary arteries
Quality of life
Review
Risk factors
Surgical anastomosis
Veins & arteries
Workloads
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Title Interatrial shunt devices for heart failure with normal ejection fraction: a technology update
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