Interatrial shunt devices for heart failure with normal ejection fraction: a technology update

Heart failure with normal ejection fraction (HeFNEF) accounts for ~50% of heart failure admissions. Its pathophysiology and diagnostic criteria are yet to be defined clearly which may hinder the search for effective treatments. The clinical hallmark of HeFNEF is exertional breathlessness, often due...

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Bibliographic Details
Published inMedical devices (Auckland, N.Z.) Vol. 10; pp. 123 - 132
Main Authors Cuthbert, Joseph J, Pellicori, Pierpaolo, Clark, Andrew L
Format Journal Article Book Review
LanguageEnglish
Published New Zealand Dove Medical Press Limited 01.01.2017
Taylor & Francis Ltd
Dove Medical Press
Subjects
Anticoagulants
Cardiology
Cardiovascular disease
Care and treatment
Congenital diseases
Defects
Heart failure
Heart failure with normal ejection fraction. Heart failure with normal ejection fraction. Interatrial shunt devices. IASD. V-Wave. Device therapy
Hypertension
Medical prognosis
Mortality
Pulmonary arteries
Quality of life
Review
Risk factors
Surgical anastomosis
Veins & arteries
Workloads
New York
United States > US
device therapy
V-Wave
preserved EF
HeFPEF
review
HFpEF
HeFNEF
IASD
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Summary:Heart failure with normal ejection fraction (HeFNEF) accounts for ~50% of heart failure admissions. Its pathophysiology and diagnostic criteria are yet to be defined clearly which may hinder the search for effective treatments. The clinical hallmark of HeFNEF is exertional breathlessness, often due to an abnormal increase in left atrial pressure during exercise. Creation of an interatrial communication to offload the left atrium is a possible therapeutic approach. There are two percutaneously delivered devices currently under investigation which are discussed in this review.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:1179-1470
1179-1470
DOI:10.2147/MDER.S113105