A flexible forward simulator for populations subject to selection and demography

• Published in: Bioinformatics Vol. 24; no. 23; pp. 2786 - 2787
• Main Author: Hernandez, Ryan D.
• Format: Journal Article
• Language: English
• Published: Oxford Oxford University Press 01.12.2008; Oxford Publishing Limited (England)
• Subjects: Algorithms; Applications Note; Biological and medical sciences; Biological Evolution; Computer Simulation; Demography; Fundamental and applied biological sciences. Psychology; General aspects; Genetic diversity; Genetics, Population; Genome, Human; Humans; Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects); Models, Genetic; Population - genetics; Selection, Genetic; Software; Population; Bioinformatics; Selection

This article introduces a new forward population genetic simulation program that can efficiently generate samples from populations with complex demographic histories under various models of natural selection. The program (SFS_CODE) is highly flexible, allowing the user to simulate realistic genomic...