The importance of GLP-1 and PYY in resistant starch's effect on body fat in mice

• Published in: Molecular nutrition & food research Vol. 59; no. 5; pp. 1000 - 1003
• Main Authors: Zhou, June, Martin, Roy J., Raggio, Anne M., Shen, Li, McCutcheon, Kathleen, Keenan, Michael J.
• Format: Journal Article
• Language: English
• Published: Germany Blackwell Publishing Ltd 01.05.2015
• Subjects: Adipose Tissue - metabolism; Animals; Antagonist; antagonists; body fat; body weight; Dietary Fiber; Dietary Fiber - pharmacology; fermentation; food intake; gene expression; genotype; GLP-1 receptor; glucagon-like peptide 1; Glucagon-Like Peptide 1 - blood; Glucagon-Like Peptide 1 - physiology; intraperitoneal injection; messenger RNA; Mice; Obesity; peptide YY; Peptide YY - blood; Peptide YY - physiology; PYY receptor; resistant starch; secretion; Starch - pharmacology; Obesity; Dietary Fiber; Antagonist; GLP-1 receptor; PYY receptor

Resistant starch (RS) is a dietary fermentable fiber that decreases body fat accumulation, and stimulates the secretion of glucagon‐like peptide‐1 (GLP‐1) and peptide YY (PYY) in rodents. GLP‐1 and PYY are gut‐secreted hormones with antiobesity effect. Thus, blocking the signals of increased GLP‐1 a...