Improved EEG source analysis using low-resolution conductivity estimation in a four-compartment finite element head model

• Published in: Human brain mapping Vol. 30; no. 9; pp. 2862 - 2878
• Main Authors: Lew, Seok, Wolters, Carsten H., Anwander, Alfred, Makeig, Scott, MacLeod, Rob S.
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 15.09.2009; Wiley-Liss
• Subjects: Algorithms; Biological and medical sciences; Brain - anatomy & histology; Brain - physiology; brain and skull conductivity; Brain Mapping - methods; cerebrospinal fluid; Cerebrospinal Fluid - physiology; EEG; Electric Conductivity; Electrodiagnosis. Electric activity recording; Electroencephalography - methods; Evoked Potentials, Somatosensory - physiology; Finite Element Analysis; finite element method; Head - anatomy & histology; Head - physiology; Humans; Image Processing, Computer-Assisted - methods; in vivo conductivity estimation; Investigative techniques, diagnostic techniques (general aspects); Magnetic Resonance Imaging - methods; Male; Medical sciences; Nervous system; Physical Stimulation; Radiodiagnosis. Nmr imagery. Nmr spectrometry; realistic four-compartment head modeling; Scalp - anatomy & histology; Scalp - physiology; Signal Processing, Computer-Assisted; simulated annealing; Skull - anatomy & histology; Skull - physiology; Somatosensory Cortex - anatomy & histology; Somatosensory Cortex - physiology; somatosensory-evoked potentials; source analysis; Subarachnoid Space - physiology; T1- and PD-weighted MRI; Touch - physiology; Touch Perception - physiology; Young Adult; source analysis; Nervous system diseases; Head; Radiodiagnosis; Estimation; EEG; Central nervous system; Electrophysiology; Conductivity; Electroencephalography; somatosensory-evoked potentials; Cerebrospinal fluid; Nuclear magnetic resonance imaging; Modeling; Encephalon; Finite element method; in vivo conductivity estimation; Simulated annealing; Skull; T1- and PD-weighted MRI; Models; Somatosensory evoked potential; brain and skull conductivity; realistic four-compartment head modeling

Bioelectric source analysis in the human brain from scalp electroencephalography (EEG) signals is sensitive to geometry and conductivity properties of the different head tissues. We propose a low‐resolution conductivity estimation (LRCE) method using simulated annealing optimization on high‐resoluti...