Antigenic variants of influenza B viruses isolated in Japan during the 2017‐2018 and 2018‐2019 influenza seasons

• Published in: Influenza and other respiratory viruses Vol. 14; no. 3; pp. 311 - 319
• Main Authors: Kato‐Miyashita, Sari, Sakai‐Tagawa, Yuko, Yamashita, Makoto, Iwatsuki‐Horimoto, Kiyoko, Ito, Mutsumi, Tokita, Akifumi, Hagiwara, Haruhisa, Izumida, Naomi, Nishino, Tamon, Wada, Noriyuki, Koga, Michiko, Adachi, Eisuke, Jubishi, Daisuke, Yotsuyanagi, Hiroshi, Kawaoka, Yoshihiro, Imai, Masaki
• Format: Journal Article
• Language: English
• Published: England John Wiley & Sons, Inc 01.05.2020; John Wiley and Sons Inc
• Subjects: Adult; Amino acids; Analysis; Animals; Antigenic variants; Antigenic Variation; antigenicity; Antigens; Cell culture; Deletion; Epidemics; Exo-a-sialidase; Female; Ferrets; Fluorescence; Hemagglutination inhibition; Hemagglutination Inhibition Tests; hemagglutinin; Hemagglutinin Glycoproteins, Influenza Virus - genetics; Hemagglutinin Glycoproteins, Influenza Virus - immunology; Hemagglutinins; Humans; Influenza; Influenza B; influenza B virus; Influenza B virus - classification; Influenza B virus - genetics; Influenza B virus - immunology; Influenza B virus - isolation & purification; Influenza, Human - epidemiology; Influenza, Human - virology; Japan; Japan - epidemiology; Laninamivir; Lectins; Medical research; Mutation; neuraminidase inhibitors; Original; Phylogeny; Plasmids; Respiratory diseases; RNA polymerase; Seasons; Vaccines; Viruses; Zanamivir; Japan; United Kingdom > UK; antigenicity; neuraminidase inhibitors; Japan; hemagglutinin; influenza B virus

Background Here, we genetically and antigenically analyzed influenza B viruses (IBVs) isolated in Japan during the 2017‐2018 and 2018‐2019 influenza seasons. Methods A total of 68 IBVs (61 B/Yamagata/16/88‐like [B/Yamagata]‐lineage and 7 B/Victoria/2/87‐like [B/Victoria]‐lineage) were antigenically...