Supraspinal nociceptive networks in neuropathic pain after spinal cord injury

• Published in: Human brain mapping Vol. 42; no. 12; pp. 3733 - 3749
• Main Authors: Huynh, Vincent, Lütolf, Robin, Rosner, Jan, Luechinger, Roger, Curt, Armin, Kollias, Spyridon, Hubli, Michèle, Michels, Lars
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 15.08.2021
• Subjects: Adult; Aged; Cerebral Cortex - diagnostic imaging; Cerebral Cortex - physiopathology; Chronic Disease; Connectome; contact heat evoked potentials; Cortex (insular); Cortex (somatosensory); Diabetic neuropathy; Evoked Potentials - physiology; Female; Fibromyalgia; Humans; Information processing; Magnetic Resonance Imaging; Male; Medical imaging; Middle Aged; Nerve Net - diagnostic imaging; Nerve Net - physiopathology; Neural networks; Neuralgia; Neuralgia - diagnostic imaging; Neuralgia - physiopathology; Neuroimaging; neuropathic pain; Nociception - physiology; Pain; pain extent; Pain perception; Paralysis; Paraplegia - diagnostic imaging; Paraplegia - etiology; Paraplegia - physiopathology; Paraplegics; Phenotypes; Plasticity; quantitative sensory testing; resting‐state functional connectivity; Sensory integration; Spinal cord injuries; Spinal Cord Injuries - complications; Spinal Cord Injuries - diagnostic imaging; Spinal Cord Injuries - physiopathology; spinal cord injury; Substantia grisea; Thalamus; Thalamus - diagnostic imaging; Thalamus - physiopathology; voxel‐based morphometry; spinal cord injury; neuropathic pain; pain extent; contact heat evoked potentials; resting-state functional connectivity; voxel-based morphometry; quantitative sensory testing
• ISSN: 1065-9471; 1097-0193; 1097-0193
• DOI: 10.1002/hbm.25401

Neuropathic pain following spinal cord injury involves plastic changes along the whole neuroaxis. Current neuroimaging studies have identified grey matter volume (GMV) and resting‐state functional connectivity changes of pain processing regions related to neuropathic pain intensity in spinal cord in...