Enhancing ventrolateral prefrontal cortex activation mitigates social pain and modifies subsequent social attitudes: Insights from TMS and fMRI

• Published in: NeuroImage (Orlando, Fla.) Vol. 292; p. 120620
• Main Authors: Li, Sijin, Cao, Xueying, Li, Yiwei, Tang, Yuyao, Cheng, Si, Zhang, Dandan
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 15.04.2024; Elsevier Limited; Elsevier
• Subjects: Attitudes; Brain research; Experiments; Feedback; Functional magnetic resonance imaging; Hippocampus; Magnetic fields; Medical imaging; Neuroimaging; Pain; Peers; Prefrontal cortex; Questionnaires; Social anxiety; Social attitude; Social exclusion; Social feedback; Social interactions; Social pain; Transcranial magnetic stimulation; Ventrolateral prefrontal cortex; Well being; Social attitude; Transcranial magnetic stimulation; Social feedback; Social pain; Hippocampus; Ventrolateral prefrontal cortex

•TMS with fMRI reveals rVLPFC's causal role in social pain relief, unveiling neural circuits.•rVLPFC activation strengthens DLPFC coupling amid negative social feedback, inversely linked to subjective negativity.•Improved attitudes toward feedback senders were found with rVLPFC activation.•Hipp...