Honokiol induces apoptosis-like death in Cryptocaryon irritans Tomont
Cryptocaryon irritans, a common parasite in tropical and subtropical marine teleost fish, has caused serious harm to the marine aquaculture industry. Honokiol was proven to induce C. irritans tomont cytoplasm shrinkage and death in our previous study, but the mechanism by which it works remains unkn...
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Published in | Parasites & vectors Vol. 16; no. 1; pp. 1 - 287 |
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Main Authors | , , , , , , , , , |
Format | Journal Article |
Language | English |
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BioMed Central Ltd
16.08.2023
BioMed Central BMC |
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Abstract | Cryptocaryon irritans, a common parasite in tropical and subtropical marine teleost fish, has caused serious harm to the marine aquaculture industry. Honokiol was proven to induce C. irritans tomont cytoplasm shrinkage and death in our previous study, but the mechanism by which it works remains unknown. In this study, the changes of apoptotic morphology and apoptotic ratio were detected by microscopic observation and AnnexinV-FITC/PI staining. The effects of honokiol on intracellular calcium ([Ca.sup.2+].sub.i) concentration, mitochondrial membrane potential ([DELA]Ψm), reactive oxygen species (ROS), quantity of DNA fragmentations (QDF) and caspase activities were detected by Fluo-3 staining, JC-1 staining, DCFH-DA staining, Tunel method and caspase activity assay kit. The effects of honokiol on mRNA expression levels of 61 apoptosis-related genes in tomonts of C. irritans were detected by real-time PCR. The results of the study on the effects of honokiol concentration on C. irritans tomont apoptosis-like death showed that the highest levels of prophase apoptosis-like death rate (PADR), [Ca.sup.2+].sub.i concentration, ROS, the activities of caspase-3/9 and the lowest necrosis ratio (NER) were obtained at a concentration of 1 [mu]g/ml, which was considered the most suitable for inducing C. irritans tomont apoptosis-like death. When C. irritans tomonts were treated with 1 [mu]g/ml honokiol, the [Ca.sup.2+].sub.i concentration began to increase significantly at 1 h. Following this, the ROS, QDF and activities of caspase-3/9 began to increase significantly, and the [DELA]Ψm began to decrease significantly at 2 h; the highest PADR was obtained at 4 h. The mRNA expression of 14 genes was significantly upregulated during honokiol treatment. Of these genes, itpr2, capn1, mc, actg1, actb, parp2, traf2 and fos were enriched in the pathway related to apoptosis induced by endoplasmic reticulum (ER) stress. This article shows that honokiol can induce C. irritans tomont apoptosis-like death. These results suggest that honokiol may disrupt [Ca.sup.2+].sub.i homeostasis in ER and then induce C. irritans tomont apoptosis-like death by caspase cascade or mitochondrial pathway, which might represent a novel therapeutic intervention for C. irritans infection. |
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AbstractList | BACKGROUNDCryptocaryon irritans, a common parasite in tropical and subtropical marine teleost fish, has caused serious harm to the marine aquaculture industry. Honokiol was proven to induce C. irritans tomont cytoplasm shrinkage and death in our previous study, but the mechanism by which it works remains unknown.METHODSIn this study, the changes of apoptotic morphology and apoptotic ratio were detected by microscopic observation and AnnexinV-FITC/PI staining. The effects of honokiol on intracellular calcium ([Ca2+]i) concentration, mitochondrial membrane potential (ΔΨm), reactive oxygen species (ROS), quantity of DNA fragmentations (QDF) and caspase activities were detected by Fluo-3 staining, JC-1 staining, DCFH-DA staining, Tunel method and caspase activity assay kit. The effects of honokiol on mRNA expression levels of 61 apoptosis-related genes in tomonts of C. irritans were detected by real-time PCR.RESULTSThe results of the study on the effects of honokiol concentration on C. irritans tomont apoptosis-like death showed that the highest levels of prophase apoptosis-like death rate (PADR), [Ca2+]i concentration, ROS, the activities of caspase-3/9 and the lowest necrosis ratio (NER) were obtained at a concentration of 1 μg/ml, which was considered the most suitable for inducing C. irritans tomont apoptosis-like death. When C. irritans tomonts were treated with 1 μg/ml honokiol, the [Ca2+]i concentration began to increase significantly at 1 h. Following this, the ROS, QDF and activities of caspase-3/9 began to increase significantly, and the ΔΨm began to decrease significantly at 2 h; the highest PADR was obtained at 4 h. The mRNA expression of 14 genes was significantly upregulated during honokiol treatment. Of these genes, itpr2, capn1, mc, actg1, actb, parp2, traf2 and fos were enriched in the pathway related to apoptosis induced by endoplasmic reticulum (ER) stress.CONCLUSIONSThis article shows that honokiol can induce C. irritans tomont apoptosis-like death. These results suggest that honokiol may disrupt [Ca2+]i homeostasis in ER and then induce C. irritans tomont apoptosis-like death by caspase cascade or mitochondrial pathway, which might represent a novel therapeutic intervention for C. irritans infection. Background Cryptocaryon irritans, a common parasite in tropical and subtropical marine teleost fish, has caused serious harm to the marine aquaculture industry. Honokiol was proven to induce C. irritans tomont cytoplasm shrinkage and death in our previous study, but the mechanism by which it works remains unknown. Methods In this study, the changes of apoptotic morphology and apoptotic ratio were detected by microscopic observation and AnnexinV-FITC/PI staining. The effects of honokiol on intracellular calcium ([Ca.sup.2+].sub.i) concentration, mitochondrial membrane potential ([DELA]Ψm), reactive oxygen species (ROS), quantity of DNA fragmentations (QDF) and caspase activities were detected by Fluo-3 staining, JC-1 staining, DCFH-DA staining, Tunel method and caspase activity assay kit. The effects of honokiol on mRNA expression levels of 61 apoptosis-related genes in tomonts of C. irritans were detected by real-time PCR. Results The results of the study on the effects of honokiol concentration on C. irritans tomont apoptosis-like death showed that the highest levels of prophase apoptosis-like death rate (PADR), [Ca.sup.2+].sub.i concentration, ROS, the activities of caspase-3/9 and the lowest necrosis ratio (NER) were obtained at a concentration of 1 [mu]g/ml, which was considered the most suitable for inducing C. irritans tomont apoptosis-like death. When C. irritans tomonts were treated with 1 [mu]g/ml honokiol, the [Ca.sup.2+].sub.i concentration began to increase significantly at 1 h. Following this, the ROS, QDF and activities of caspase-3/9 began to increase significantly, and the [DELA]Ψm began to decrease significantly at 2 h; the highest PADR was obtained at 4 h. The mRNA expression of 14 genes was significantly upregulated during honokiol treatment. Of these genes, itpr2, capn1, mc, actg1, actb, parp2, traf2 and fos were enriched in the pathway related to apoptosis induced by endoplasmic reticulum (ER) stress. Conclusions This article shows that honokiol can induce C. irritans tomont apoptosis-like death. These results suggest that honokiol may disrupt [Ca.sup.2+].sub.i homeostasis in ER and then induce C. irritans tomont apoptosis-like death by caspase cascade or mitochondrial pathway, which might represent a novel therapeutic intervention for C. irritans infection. Graphical abstract Keywords: Cryptocaryon irritans, Honokiol, Apoptosis-like death, Endoplasmic reticulum stress Abstract Background Cryptocaryon irritans , a common parasite in tropical and subtropical marine teleost fish, has caused serious harm to the marine aquaculture industry. Honokiol was proven to induce C. irritans tomont cytoplasm shrinkage and death in our previous study, but the mechanism by which it works remains unknown. Methods In this study, the changes of apoptotic morphology and apoptotic ratio were detected by microscopic observation and AnnexinV-FITC/PI staining. The effects of honokiol on intracellular calcium ([Ca 2+ ] i ) concentration, mitochondrial membrane potential (Δ Ψ m), reactive oxygen species (ROS), quantity of DNA fragmentations (QDF) and caspase activities were detected by Fluo-3 staining, JC-1 staining, DCFH-DA staining, Tunel method and caspase activity assay kit. The effects of honokiol on mRNA expression levels of 61 apoptosis-related genes in tomonts of C. irritans were detected by real-time PCR. Results The results of the study on the effects of honokiol concentration on C. irritans tomont apoptosis-like death showed that the highest levels of prophase apoptosis-like death rate (PADR), [Ca 2+ ] i concentration, ROS, the activities of caspase-3/9 and the lowest necrosis ratio (NER) were obtained at a concentration of 1 μg/ml, which was considered the most suitable for inducing C. irritans tomont apoptosis-like death. When C. irritans tomonts were treated with 1 μg/ml honokiol, the [Ca 2+ ] i concentration began to increase significantly at 1 h. Following this, the ROS, QDF and activities of caspase-3/9 began to increase significantly, and the Δ Ψ m began to decrease significantly at 2 h; the highest PADR was obtained at 4 h. The mRNA expression of 14 genes was significantly upregulated during honokiol treatment. Of these genes, itpr2 , capn1 , mc , actg1 , actb , parp2 , traf2 and fos were enriched in the pathway related to apoptosis induced by endoplasmic reticulum (ER) stress. Conclusions This article shows that honokiol can induce C. irritans tomont apoptosis-like death. These results suggest that honokiol may disrupt [Ca 2+ ] i homeostasis in ER and then induce C. irritans tomont apoptosis-like death by caspase cascade or mitochondrial pathway, which might represent a novel therapeutic intervention for C. irritans infection. Graphical abstract Abstract Background Cryptocaryon irritans, a common parasite in tropical and subtropical marine teleost fish, has caused serious harm to the marine aquaculture industry. Honokiol was proven to induce C. irritans tomont cytoplasm shrinkage and death in our previous study, but the mechanism by which it works remains unknown. Methods In this study, the changes of apoptotic morphology and apoptotic ratio were detected by microscopic observation and AnnexinV-FITC/PI staining. The effects of honokiol on intracellular calcium ([Ca2+]i) concentration, mitochondrial membrane potential (ΔΨm), reactive oxygen species (ROS), quantity of DNA fragmentations (QDF) and caspase activities were detected by Fluo-3 staining, JC-1 staining, DCFH-DA staining, Tunel method and caspase activity assay kit. The effects of honokiol on mRNA expression levels of 61 apoptosis-related genes in tomonts of C. irritans were detected by real-time PCR. Results The results of the study on the effects of honokiol concentration on C. irritans tomont apoptosis-like death showed that the highest levels of prophase apoptosis-like death rate (PADR), [Ca2+]i concentration, ROS, the activities of caspase-3/9 and the lowest necrosis ratio (NER) were obtained at a concentration of 1 μg/ml, which was considered the most suitable for inducing C. irritans tomont apoptosis-like death. When C. irritans tomonts were treated with 1 μg/ml honokiol, the [Ca2+]i concentration began to increase significantly at 1 h. Following this, the ROS, QDF and activities of caspase-3/9 began to increase significantly, and the ΔΨm began to decrease significantly at 2 h; the highest PADR was obtained at 4 h. The mRNA expression of 14 genes was significantly upregulated during honokiol treatment. Of these genes, itpr2, capn1, mc, actg1, actb, parp2, traf2 and fos were enriched in the pathway related to apoptosis induced by endoplasmic reticulum (ER) stress. Conclusions This article shows that honokiol can induce C. irritans tomont apoptosis-like death. These results suggest that honokiol may disrupt [Ca2+]i homeostasis in ER and then induce C. irritans tomont apoptosis-like death by caspase cascade or mitochondrial pathway, which might represent a novel therapeutic intervention for C. irritans infection. Graphical abstract Cryptocaryon irritans, a common parasite in tropical and subtropical marine teleost fish, has caused serious harm to the marine aquaculture industry. Honokiol was proven to induce C. irritans tomont cytoplasm shrinkage and death in our previous study, but the mechanism by which it works remains unknown. In this study, the changes of apoptotic morphology and apoptotic ratio were detected by microscopic observation and AnnexinV-FITC/PI staining. The effects of honokiol on intracellular calcium ([Ca.sup.2+].sub.i) concentration, mitochondrial membrane potential ([DELA]Ψm), reactive oxygen species (ROS), quantity of DNA fragmentations (QDF) and caspase activities were detected by Fluo-3 staining, JC-1 staining, DCFH-DA staining, Tunel method and caspase activity assay kit. The effects of honokiol on mRNA expression levels of 61 apoptosis-related genes in tomonts of C. irritans were detected by real-time PCR. The results of the study on the effects of honokiol concentration on C. irritans tomont apoptosis-like death showed that the highest levels of prophase apoptosis-like death rate (PADR), [Ca.sup.2+].sub.i concentration, ROS, the activities of caspase-3/9 and the lowest necrosis ratio (NER) were obtained at a concentration of 1 [mu]g/ml, which was considered the most suitable for inducing C. irritans tomont apoptosis-like death. When C. irritans tomonts were treated with 1 [mu]g/ml honokiol, the [Ca.sup.2+].sub.i concentration began to increase significantly at 1 h. Following this, the ROS, QDF and activities of caspase-3/9 began to increase significantly, and the [DELA]Ψm began to decrease significantly at 2 h; the highest PADR was obtained at 4 h. The mRNA expression of 14 genes was significantly upregulated during honokiol treatment. Of these genes, itpr2, capn1, mc, actg1, actb, parp2, traf2 and fos were enriched in the pathway related to apoptosis induced by endoplasmic reticulum (ER) stress. This article shows that honokiol can induce C. irritans tomont apoptosis-like death. These results suggest that honokiol may disrupt [Ca.sup.2+].sub.i homeostasis in ER and then induce C. irritans tomont apoptosis-like death by caspase cascade or mitochondrial pathway, which might represent a novel therapeutic intervention for C. irritans infection. |
ArticleNumber | 287 |
Audience | Academic |
Author | Deng, Heng-Wei Zhou, Yong-Can Lin, Chuan Zhao, Zi-Chen Jiang, Man-Yi Huang, Ji-Hui Huang, Qing-Qin Liu, Shao-Long Zhong, Zhi-Hong Guo, Wei-Liang |
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CitedBy_id | crossref_primary_10_1016_j_ejmech_2024_116471 crossref_primary_10_1016_j_aquaculture_2024_740625 |
Cites_doi | 10.1186/s13071-016-1550-1 10.1086/379286 10.3390/cells10102509 10.1007/s10495-013-0832-8 10.1074/jbc.M110.201889 10.1016/j.molonc.2014.12.009 10.1089/ars.2006.8.1391 10.3389/fphar.2019.00790 10.1007/s00436-006-0151-x 10.1111/j.1471-4159.2012.07859.x 10.1016/j.pt.2007.06.004 10.1186/1471-2164-11-76 10.1186/s13071-016-1919-1 10.3390/ijms23094588 10.1016/j.semcdb.2015.01.006 10.3389/fcimb.2012.00095 10.1016/j.ijbiomac.2019.04.090 10.1093/nar/gks596 10.1042/BJ20081386 10.1038/s41467-018-05588-5 10.1073/pnas.1718336115 10.1111/j.1478-3231.2008.01767.x 10.1016/j.canlet.2015.08.030 10.1111/jfd.13346 10.1016/j.lfs.2019.01.046 10.1038/s41586-020-2725-7 10.1038/cdd.2008.150 10.1016/j.placenta.2017.07.004 10.1016/j.biomaterials.2015.02.091 10.1016/j.femsyr.2005.08.001 10.1007/s004360000364 10.3390/nu10081021 10.3147/jsfp.51.103 10.7314/APJCP.2015.16.6.2129 10.1080/01926230701320337 10.1002/cbin.11137 10.1371/journal.ppat.1002320 10.1210/en.2013-1519 10.3390/ph14060552 10.1007/s11033-018-4258-9 10.1186/s12864-018-4565-5 10.1016/j.canlet.2018.10.026 10.1016/j.aquaculture.2006.04.026 10.1038/s41418-017-0012-4 10.1111/j.1365-2761.2005.00622.x 10.1146/annurev-pathol-012513-104649 10.1111/j.1745-7270.2005.00108.x 10.1038/sj.onc.1202558 10.1016/j.ceca.2017.05.003 10.1038/s41467-021-23800-x 10.1038/sj.onc.1207108 10.1016/j.cell.2004.11.048 10.1016/j.molbiopara.2014.09.002 10.1016/j.placenta.2016.04.001 10.1007/978-94-007-2869-1_7 10.1002/bies.20085 10.1016/j.canlet.2009.08.032 10.1051/parasite/2019071 10.1016/j.aquaculture.2018.10.037 |
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References_xml | – volume: 137 start-page: 1755 year: 2018 ident: 5910_CR4 publication-title: IOP Conf Series: Earth Environ Sci contributor: fullname: KV Van – volume: 9 start-page: 280 year: 2016 ident: 5910_CR24 publication-title: Parasit Vectors doi: 10.1186/s13071-016-1550-1 contributor: fullname: F Yin – volume: 73 start-page: 1082 year: 2003 ident: 5910_CR61 publication-title: Am J Hum Genet doi: 10.1086/379286 contributor: fullname: M Zhu – volume: 10 start-page: 2509 year: 2021 ident: 5910_CR9 publication-title: Cells doi: 10.3390/cells10102509 contributor: fullname: R Sugiura – volume: 14 year: 2019 ident: 5910_CR19 publication-title: PLoS ONE contributor: fullname: Q Ye – volume: 18 start-page: 664 year: 2013 ident: 5910_CR18 publication-title: Apopt Int J Program Cell Death doi: 10.1007/s10495-013-0832-8 contributor: fullname: AD Ni Nyoman – volume: 286 start-page: 13638 year: 2011 ident: 5910_CR39 publication-title: J Biol Chem doi: 10.1074/jbc.M110.201889 contributor: fullname: S Dolai – volume: 11 start-page: 1 year: 1951 ident: 5910_CR1 publication-title: Sci Meet Zool Soc Lond contributor: fullname: EM Brown – volume: 9 start-page: 834 year: 2015 ident: 5910_CR42 publication-title: Mol Oncol doi: 10.1016/j.molonc.2014.12.009 contributor: fullname: SH Liu – volume: 8 start-page: 1391 year: 2006 ident: 5910_CR56 publication-title: Antioxid Redox Signal doi: 10.1089/ars.2006.8.1391 contributor: fullname: A Görlach – volume: 10 start-page: 790 year: 2019 ident: 5910_CR53 publication-title: Front Pharmacol doi: 10.3389/fphar.2019.00790 contributor: fullname: R Dixit – volume: 99 start-page: 160 year: 2006 ident: 5910_CR2 publication-title: Parasitol Res doi: 10.1007/s00436-006-0151-x contributor: fullname: HY Sun – volume: 123 start-page: 147 year: 2012 ident: 5910_CR51 publication-title: J Neurochem doi: 10.1111/j.1471-4159.2012.07859.x contributor: fullname: CM Kopil – volume: 23 start-page: 376 year: 2007 ident: 5910_CR17 publication-title: Trends Parasitol doi: 10.1016/j.pt.2007.06.004 contributor: fullname: I Bruchhaus – volume: 11 start-page: 76 year: 2010 ident: 5910_CR22 publication-title: BMC Genomics doi: 10.1186/1471-2164-11-76 contributor: fullname: Y Lokanathan – volume: 9 start-page: 630 year: 2016 ident: 5910_CR23 publication-title: Parasit Vectors doi: 10.1186/s13071-016-1919-1 contributor: fullname: ZQ Mo – volume: 27 start-page: 51 year: 2016 ident: 5910_CR47 publication-title: Reproduct Contraception contributor: fullname: KS Liu – volume: 23 start-page: 4588 year: 2022 ident: 5910_CR54 publication-title: Int J Mol Sci doi: 10.3390/ijms23094588 contributor: fullname: SU Huh – volume: 39 start-page: 20 year: 2015 ident: 5910_CR10 publication-title: Semin Cell Dev Biol doi: 10.1016/j.semcdb.2015.01.006 contributor: fullname: S Fulda – volume: 2 start-page: 95 year: 2012 ident: 5910_CR12 publication-title: Front Cell Infect Microbiol doi: 10.3389/fcimb.2012.00095 contributor: fullname: S Gannavaram – volume: 133 start-page: 316 year: 2019 ident: 5910_CR33 publication-title: Int J Biol Macromol doi: 10.1016/j.ijbiomac.2019.04.090 contributor: fullname: Z Li – volume: 40 year: 2012 ident: 5910_CR70 publication-title: Nucleic Acids Res doi: 10.1093/nar/gks596 contributor: fullname: A Untergasser – volume: 417 start-page: 1 year: 2009 ident: 5910_CR55 publication-title: Biochem J doi: 10.1042/BJ20081386 contributor: fullname: MP Murphy – volume: 8 start-page: 1775 year: 1988 ident: 5910_CR62 publication-title: Mol Cell Biol contributor: fullname: HP Erba – volume: 12 year: 2022 ident: 5910_CR34 publication-title: Front Genet contributor: fullname: Y Bai – volume: 9 start-page: 3233 year: 2018 ident: 5910_CR64 publication-title: Nat Commun doi: 10.1038/s41467-018-05588-5 contributor: fullname: Q Chen – volume: 115 start-page: 4399 year: 2018 ident: 5910_CR63 publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.1718336115 contributor: fullname: A Drazic – volume: 28 start-page: 1458 year: 2008 ident: 5910_CR27 publication-title: Liver Int doi: 10.1111/j.1478-3231.2008.01767.x contributor: fullname: J Deng – volume: 370 start-page: 66 year: 2016 ident: 5910_CR37 publication-title: Cancer Lett doi: 10.1016/j.canlet.2015.08.030 contributor: fullname: PS Yeh – volume: 44 start-page: 881 year: 2021 ident: 5910_CR21 publication-title: J Fish Dis doi: 10.1111/jfd.13346 contributor: fullname: S Qu – volume: 221 start-page: 204 year: 2019 ident: 5910_CR30 publication-title: Life Sci doi: 10.1016/j.lfs.2019.01.046 contributor: fullname: J Zhu – volume: 585 start-page: 609 year: 2020 ident: 5910_CR65 publication-title: Nature doi: 10.1038/s41586-020-2725-7 contributor: fullname: S Bilokapic – volume: 16 start-page: 3 year: 2009 ident: 5910_CR35 publication-title: Cell Death Differ doi: 10.1038/cdd.2008.150 contributor: fullname: G Kroemer – volume: 57 start-page: 163 year: 2017 ident: 5910_CR46 publication-title: Placenta doi: 10.1016/j.placenta.2017.07.004 contributor: fullname: D Bastida-Ruiz – volume: 53 start-page: 274 year: 2015 ident: 5910_CR48 publication-title: Biomaterials doi: 10.1016/j.biomaterials.2015.02.091 contributor: fullname: JH Cho – volume: 5 start-page: 1193 year: 2005 ident: 5910_CR60 publication-title: FEMS Yeast Res doi: 10.1016/j.femsyr.2005.08.001 contributor: fullname: CW Gourlay – volume: 87 start-page: 362 year: 2001 ident: 5910_CR15 publication-title: Parasitol Res doi: 10.1007/s004360000364 contributor: fullname: KS Tan – volume: 10 start-page: 1021 year: 2018 ident: 5910_CR8 publication-title: Nutrients doi: 10.3390/nu10081021 contributor: fullname: C Kim – volume: 51 start-page: 103 year: 2016 ident: 5910_CR3 publication-title: Japan Fish Pathol doi: 10.3147/jsfp.51.103 contributor: fullname: M Imajoh – volume: 16 start-page: 2129 year: 2015 ident: 5910_CR7 publication-title: Asian Pacific J Cancer Prev doi: 10.7314/APJCP.2015.16.6.2129 contributor: fullname: S Goldar – volume: 35 start-page: 495 year: 2007 ident: 5910_CR67 publication-title: Toxicol Pathol doi: 10.1080/01926230701320337 contributor: fullname: S Elmore – volume: 43 start-page: 582 year: 2019 ident: 5910_CR69 publication-title: Cell Biol Int doi: 10.1002/cbin.11137 contributor: fullname: MS D'Arcy – volume: 7 year: 2011 ident: 5910_CR13 publication-title: PLoS Pathog doi: 10.1371/journal.ppat.1002320 contributor: fullname: SE Reece – volume: 155 start-page: 758 year: 2014 ident: 5910_CR50 publication-title: Endocrinology doi: 10.1210/en.2013-1519 contributor: fullname: T Hara – volume: 14 start-page: 552 year: 2021 ident: 5910_CR20 publication-title: Pharmaceuticals doi: 10.3390/ph14060552 contributor: fullname: CJ Bethencourt-Estrella – volume: 45 start-page: 1469 year: 2018 ident: 5910_CR68 publication-title: Mol Biol Rep doi: 10.1007/s11033-018-4258-9 contributor: fullname: P Majtnerová – volume: 19 start-page: 192 year: 2018 ident: 5910_CR25 publication-title: Cryptocaryon Irritans BMC Geno doi: 10.1186/s12864-018-4565-5 contributor: fullname: R Chen – volume: 442 start-page: 113 year: 2019 ident: 5910_CR41 publication-title: Cancer Lett doi: 10.1016/j.canlet.2018.10.026 contributor: fullname: CS Chiu – volume: 258 start-page: 127 year: 2006 ident: 5910_CR5 publication-title: Aquaculture doi: 10.1016/j.aquaculture.2006.04.026 contributor: fullname: XM Dan – volume: 1 year: 2010 ident: 5910_CR14 publication-title: Cell Death Dis contributor: fullname: JH Ch'ng – volume: 25 start-page: 486 year: 2018 ident: 5910_CR6 publication-title: Cell Death Differ doi: 10.1038/s41418-017-0012-4 contributor: fullname: L Galluzzi – volume: 28 start-page: 213 year: 2005 ident: 5910_CR16 publication-title: J Fish Dis doi: 10.1111/j.1365-2761.2005.00622.x contributor: fullname: DH Xu – volume: 368 year: 2022 ident: 5910_CR32 publication-title: Food Chem contributor: fullname: L Zhang – volume: 10 start-page: 173 year: 2015 ident: 5910_CR40 publication-title: Annu Rev Pathol doi: 10.1146/annurev-pathol-012513-104649 contributor: fullname: SA Oakes – volume: 37 start-page: 719 year: 2005 ident: 5910_CR52 publication-title: Acta Biochim Biophys Sin doi: 10.1111/j.1745-7270.2005.00108.x contributor: fullname: TJ Fan – volume: 18 start-page: 2423 year: 1999 ident: 5910_CR58 publication-title: Oncogene doi: 10.1038/sj.onc.1202558 contributor: fullname: T Mashima – volume: 69 start-page: 62 year: 2018 ident: 5910_CR44 publication-title: Cell Calcium doi: 10.1016/j.ceca.2017.05.003 contributor: fullname: S Marchi – volume: 12 start-page: 3479 year: 2021 ident: 5910_CR66 publication-title: Nat Commun doi: 10.1038/s41467-021-23800-x contributor: fullname: E Obaji – volume: 22 start-page: 8608 year: 2003 ident: 5910_CR43 publication-title: Oncogene doi: 10.1038/sj.onc.1207108 contributor: fullname: DG Breckenridge – volume: 120 start-page: 85 year: 2005 ident: 5910_CR49 publication-title: Cell doi: 10.1016/j.cell.2004.11.048 contributor: fullname: T Higo – volume: 197 start-page: 1 year: 2014 ident: 5910_CR36 publication-title: Mol Biochem Parasitol doi: 10.1016/j.molbiopara.2014.09.002 contributor: fullname: S Dolai – volume: 52 start-page: 146 year: 2017 ident: 5910_CR45 publication-title: Placenta doi: 10.1016/j.placenta.2016.04.001 contributor: fullname: GJ Burton – volume: 942 start-page: 157 year: 2012 ident: 5910_CR57 publication-title: Adv Exp Med Biol doi: 10.1007/978-94-007-2869-1_7 contributor: fullname: J Estaquier – volume: 26 start-page: 882 year: 2004 ident: 5910_CR59 publication-title: BioEssays doi: 10.1002/bies.20085 contributor: fullname: JC Amé – volume: 90 start-page: 153647 year: 2021 ident: 5910_CR29 publication-title: Phytomed Int J Phytother Phytopharmacol contributor: fullname: A Rauf – volume: 291 start-page: 20 year: 2010 ident: 5910_CR38 publication-title: Cancer Lett doi: 10.1016/j.canlet.2009.08.032 contributor: fullname: YJ Chen – volume: 15 year: 2020 ident: 5910_CR26 publication-title: PLoS ONE contributor: fullname: H Chi – volume: 26 start-page: 71 year: 2019 ident: 5910_CR11 publication-title: Parasite doi: 10.1051/parasite/2019071 contributor: fullname: L Basmaciyan – volume: 500 start-page: 398 year: 2019 ident: 5910_CR31 publication-title: Aquaculture doi: 10.1016/j.aquaculture.2018.10.037 contributor: fullname: ZH Zhong – volume: 12 year: 2017 ident: 5910_CR28 publication-title: PLoS ONE contributor: fullname: L Sun |
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Snippet | Abstract
Background
Cryptocaryon irritans
, a common parasite in tropical and subtropical marine teleost fish, has caused serious harm to the marine... Cryptocaryon irritans, a common parasite in tropical and subtropical marine teleost fish, has caused serious harm to the marine aquaculture industry. Honokiol... Background Cryptocaryon irritans, a common parasite in tropical and subtropical marine teleost fish, has caused serious harm to the marine aquaculture... BackgroundCryptocaryon irritans, a common parasite in tropical and subtropical marine teleost fish, has caused serious harm to the marine aquaculture industry.... BACKGROUNDCryptocaryon irritans, a common parasite in tropical and subtropical marine teleost fish, has caused serious harm to the marine aquaculture industry.... Abstract Background Cryptocaryon irritans, a common parasite in tropical and subtropical marine teleost fish, has caused serious harm to the marine aquaculture... |
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SubjectTerms | Apoptosis Apoptosis-like death Aquaculture Aquaculture industry Aqueous solutions Calcium Calcium (intracellular) Calcium (mitochondrial) Calcium homeostasis Calcium ions Caspase-3 Cryptocaryon irritans Cytoplasm Death Deoxyribonucleic acid Diagnosis DNA Endoplasmic reticulum Endoplasmic reticulum stress Ethanol Experiments Fish Fishes Fluo-3 Gene expression Genes Health aspects Homeostasis Honokiol Marine aquaculture Marine fish Marine fishes Membrane potential Mortality Necrosis Nucleotide sequence Parasites Parasitic diseases PCR Polyculture (aquaculture) Prophase Protozoa Reactive oxygen species RNA Staining TRAF2 protein Tropical diseases |
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Title | Honokiol induces apoptosis-like death in Cryptocaryon irritans Tomont |
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