NIK1-mediated translation suppression functions as a plant antiviral immunity mechanism

• Published in: Nature (London) Vol. 520; no. 7549; pp. 679 - 682
• Main Authors: Zorzatto, Cristiane, Machado, João Paulo B., Lopes, Kênia V. G., Nascimento, Kelly J. T., Pereira, Welison A., Brustolini, Otávio J. B., Reis, Pedro A. B., Calil, Iara P., Deguchi, Michihito, Sachetto-Martins, Gilberto, Gouveia, Bianca C., Loriato, Virgílio A. P., Silva, Marcos A. C., Silva, Fabyano F., Santos, Anésia A., Chory, Joanne, Fontes, Elizabeth P. B.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 30.04.2015; Nature Publishing Group
• Subjects: 13/106; 13/107; 13/109; 13/51; 13/95; 14/19; 14/63; 38/111; 38/15; 38/22; 38/39; 38/43; 38/77; 631/337/574; 631/449/2169; 631/449/2675; 82/29; Active Transport, Cell Nucleus; Arabidopsis - immunology; Arabidopsis - virology; Arabidopsis Proteins - metabolism; Begomovirus - immunology; Cell Nucleus - metabolism; Deoxyribonucleic acid; DNA; Down-Regulation; Food security; Gene expression; Gene Expression Regulation, Plant; Genetic aspects; Genotype & phenotype; Health aspects; Humanities and Social Sciences; Immune Tolerance; Immunity, Innate; Kinases; Leaves; letter; multidisciplinary; Pathogens; Plant defenses; Plant Immunity; Plant pathology; Plant-pathogen relationships; Protein Binding; Protein Biosynthesis - genetics; Protein Biosynthesis - immunology; Protein Serine-Threonine Kinases - metabolism; Protein synthesis; Proteins; Ribosomal Protein L10; Ribosomal Proteins - metabolism; Science; Transcription factors; Transcription Factors - metabolism; Translation (Genetics); Translocation; Viral infections

A new mechanism that plants use to combat begomoviruses—one of the most pathogenic groups of plant viruses, causing severe disease in major crops worldwide—is uncovered: plants inhibit the transcription of genes associated with the translational apparatus, thus causing a general reduction in protein...