Dual interaction between heartbeat-evoked responses and stimuli

• Published in: NeuroImage (Orlando, Fla.) Vol. 266; p. 119817
• Main Authors: Zhang, Yihui, Zhang, Jianfeng, Xie, Musi, Ding, Nai, Zhang, Yang, Qin, Pengmin
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.02.2023; Elsevier Limited; Elsevier
• Subjects: Brain - physiology; Brain-heart interaction; Cognitive ability; Electrocardiography; Emotions; Experiments; External stimuli; Heart; Heart Rate - physiology; Heartbeat-evoked responses; Humans; Information processing; Judgment; Magnetoencephalography; MEG; Names; Perception; Subject's own name; Brain-heart interaction; Heartbeat-evoked responses; Subject's own name; MEG
• ISSN: 1053-8119; 1095-9572; 1095-9572
• DOI: 10.1016/j.neuroimage.2022.119817

•Prestimulus heartbeat-evoked responses can affect perception of subject's own name.•Subject's own name can affect heartbeat-evoked responses.•Dual interactions between heartbeat-evoked responses and subject's own name are associated with two distinct neural pathways. Heartbeat-evoked responses (HERs) can interact with external stimuli and play a crucial role in shaping perception, self-related processes, and emotional processes. On the one hand, the external stimulus could modulate HERs. On the other hand, the HERs could affect cognitive processing of the external stimulus. Whether the same neural mechanism underlies these two processes, however, remains unclear. Here, we investigated this interactive mechanism by measuring HERs using magnetoencephalography (MEG) and two name perception tasks. Specifically, we tested (1) how hearing a subject's own name (SON) modulates HERs and (2) how the judgment of an SON is biased by prestimulus HERs. The results showed a dual interaction between HERs and SON. In particular, SON can modulate HERs for heartbeats occurring from 200 to 1200 ms after SON presentation. In addition, prestimulus HERs can bias the SON judgment when a stimulus is presented. Importantly, MEG activities from these two types of interactions differed in spatial and temporal patterns, suggesting that they may be associated with distinct neural pathways. These findings extend our understanding of brain-heart interactions.