Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS - Jovičić, Ana; Mertens, Jerome; Boeynaems, Steven; Bogaert, Elke; Chai, Noori; Yamada, Shizuka B; Paul, Joseph W; Sun, Shuying; Herdy, Joseph R; Bieri, Gregor; Kramer, Nicholas J; Gage, Fred H; et al. (Nature neuroscience, 2015)
Keywords: 14/63; 631/378/2583; 692/699/375/365/1917; Active Transport, Cell Nucleus - physiology; Amyotrophic lateral sclerosis; Amyotrophic Lateral Sclerosis - genetics; Amyotrophic Lateral Sclerosis - metabolism; Animal Genetics and Genomics; Animals; Behavioral Sciences; Biological Techniques; Biomedicine; brief-communication; C9orf72 Protein; Cell Nucleus - genetics; Cell Nucleus - metabolism; Cells, Cultured; Dipeptides - genetics; Dipeptides - metabolism; DNA Repeat Expansion - physiology; Frontotemporal dementia; Frontotemporal Dementia - genetics; Frontotemporal Dementia - metabolism; Gene Deletion; Gene mutations; Genes; Genetic aspects; Genomes; Health aspects; Humans; Localization; Medical research; Medicine; Mice; Neurobiology; Neurodegeneration; Neurosciences; Pathogenesis; Proteins; Proteins - genetics; Proteins - metabolism; Risk factors; Saccharomyces cerevisiae; Toxicity; Yeast; Yeasts; United States; La Jolla California; California; Belgium; United States--US