Technical Note: Modulation of fMRI brainstem responses by transcutaneous vagus nerve stimulation

• Published in: NeuroImage (Orlando, Fla.) Vol. 244; p. 118566
• Main Authors: Borgmann, Diba, Rigoux, Lionel, Kuzmanovic, Bojana, Edwin Thanarajah, Sharmili, Münte, Thomas F., Fenselau, Henning, Tittgemeyer, Marc
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.12.2021; Elsevier Limited; Elsevier
• Subjects: Adaptation, Physiological; Adult; Affect; Afferent Pathways - physiology; Autonomic nervous system; Autonomic Nervous System - physiology; Brain mapping; Brain stem; Brain Stem - physiology; Cross-Over Studies; Data acquisition; Decision making; Diabetes mellitus; Digestive system; Female; Functional magnetic resonance imaging; Gastrointestinal tract; Humans; Magnetic Resonance Imaging - methods; Male; Metabolism; Neuromodulation; Peripheral Nervous System - physiology; Physiology; Scanners; Sensory neurons; Signal transduction; Solitary tract nucleus; Substantia nigra; Subthalamic nucleus; Transcutaneous Electric Nerve Stimulation; Vagus nerve; Vagus Nerve - physiology; Vagus Nerve Stimulation - methods; Germany

•taVNS effects on brainstem activity are assessed during fMRI.•taVNS modulates activity in brainstem vagal afferent targets (including the NTS).•The signal dynamics over time indicates both acute, persistent and delayed effects of taVNS. Our increasing knowledge about gut-brain interaction is revolu...