Confocal Laser Scanning Microscopy for Analysis of Pseudomonas aeruginosa Biofilm Architecture and Matrix Localization

• Published in: Frontiers in microbiology Vol. 10; p. 677
• Main Authors: Reichhardt, Courtney, Parsek, Matthew R
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 02.04.2019
• Subjects: biofilm; confocal laser scanning microscopy; exopolysaccharides; flow-cell; Microbiology; Pseudomonas aeruginosa; flow-cell; Pseudomonas aeruginosa; exopolysaccharides; confocal laser scanning microscopy; biofilm

Most microbes can produce surface-associated or suspended aggregates called biofilms, which are encased within a biopolymer-rich matrix. The biofilm matrix provides structural integrity to the aggregates and shields the resident cells against environmental stressors, including antibiotic treatment....