Efficacy of 3 days/wk resistance training on myofiber hypertrophy and myogenic mechanisms in young vs. older adults

• Published in: Journal of applied physiology (1985) Vol. 101; no. 2; pp. 531 - 544
• Main Authors: Kosek, David J, Kim, Jeong-su, Petrella, John K, Cross, James M, Bamman, Marcas M
• Format: Journal Article
• Language: English
• Published: Bethesda, MD Am Physiological Soc 01.08.2006; American Physiological Society
• Subjects: Adult; Aged; Aging - physiology; Biological and medical sciences; Exercise; Exercise - physiology; Female; Fundamental and applied biological sciences. Psychology; Human subjects; Humans; Hypertrophy - pathology; Hypertrophy - physiopathology; Male; Middle Aged; Muscle Development - physiology; Muscular system; MyoD Protein - genetics; MyoD Protein - physiology; Myofibrils - pathology; Myofibrils - physiology; Myogenic Regulatory Factor 5 - genetics; Myogenic Regulatory Factor 5 - physiology; Myogenic Regulatory Factors - genetics; Myogenic Regulatory Factors - physiology; Myogenin - genetics; Myogenin - physiology; Older people; Physical training; RNA, Messenger - analysis; Sex Characteristics; Time Factors; Tissues; Weight Lifting; Human; myosin heavy chain; Vertebrata; Heavy peptide chain; Physical training; Mammalia; MyoD; myogenin; Myosin; Elderly; Hypertrophy; sarcopenia

Departments of 1 Physiology and Biophysics and 3 Surgery, University of Alabama at Birmingham, and 2 Geriatric Research, Education, and Clinical Center, Veterans Affairs Medical Center, Birmingham, Alabama Submitted 22 November 2005 ; accepted in final form 4 April 2006 Resistance training (RT) has...