singleCellBase: a high-quality manually curated database of cell markers for single cell annotation across multiple species

• Published in: Biomarker research Vol. 11; no. 1; pp. 1 - 5
• Main Authors: Meng, Fan-Lin, Huang, Xiao-Ling, Qin, Wen-Yan, Liu, Kun-Bang, Wang, Yan, Li, Ming, Ren, Yong-Hong, Li, Yan-Ze, Sun, Yi-Min
• Format: Journal Article
• Language: English
• Published: London BioMed Central Ltd 20.09.2023; BioMed Central; BMC
• Subjects: Analysis; Annotations; Automation; Cell annotation; Correspondence; Datasets; Empowerment; Genes; Genetic markers; Genomics; Interfaces; Single-cell RNA-seq; Visualization

Annotating cells in the analysis of single-cell RNA-seq (scRNA-seq) data is one of the most challenging tasks that researchers are actively addressing. Manual cell annotation is generally considered the gold standard method, although it is labor intensive and independent of prior knowledge. At prese...