Overview of the Microbiome Among Nurses study (Micro-N) as an example of prospective characterization of the microbiome within cohort studies

• Published in: Nature protocols Vol. 16; no. 6; pp. 2724 - 2731
• Main Authors: Everett, Christine, Li, Chengchen, Wilkinson, Jeremy E., Nguyen, Long H., McIver, Lauren J., Ivey, Kerry, Izard, Jacques, Palacios, Natalia, Eliassen, A. Heather, Willett, Walter C., Ascherio, Alberto, Sun, Qi, Tworoger, Shelley S., Chan, Andrew T., Garrett, Wendy S., Huttenhower, Curtis, Rimm, Eric B., Song, Mingyang
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.06.2021; Nature Publishing Group
• Subjects: 631/1647/2234; 631/326/2565/2134; 692/53; Adult; Aged; Analytical Chemistry; Biological Techniques; Biomarkers; Biomedical and Life Sciences; Cohort analysis; Computational Biology/Bioinformatics; Digestive organs; Environmental factors; Epidemiology; Feces; Female; Gastrointestinal Microbiome; Health aspects; Humans; Life Sciences; Metadata; Microarrays; Microbiomes; Microbiota; Microbiota (Symbiotic organisms); Middle Aged; Modulators; Nurses; Oral mucosa; Organic Chemistry; Perspective; Physiological aspects; Prospective Studies; Public health; Specimen Handling - instrumentation; Specimen Handling - methods; Surveys and Questionnaires; United States

A lack of prospective studies has been a major barrier for assessing the role of the microbiome in human health and disease on a population-wide scale. To address this significant knowledge gap, we have launched a large-scale collection targeting fecal and oral microbiome specimens from 20,000 women...